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  1. Article: Teaching in rural school

    Pratima Kumari

    Journal of international economic review Vol. 10, No. 1 , p. 61-65

    an experience with project method

    2017  Volume 10, Issue 1, Page(s) 61–65

    Author's details Pratima Kumari
    Keywords Constructivism ; Learner-oriented learning ; Facilitator ; Teacher-centered activities ; Projects
    Language English
    Dates of publication 2017-9999
    Publisher Serials Publ.
    Publishing place New Delhi
    Document type Article
    ZDB-ID 2426972-4
    ISSN 0975-2072
    Database ECONomics Information System

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  2. Article ; Online: Recent advancements in machine learning enabled portable and wearable biosensors

    Sachin Kadian / Pratima Kumari / Shubhangi Shukla / Roger Narayan

    Talanta Open, Vol 8, Iss , Pp 100267- (2023)

    2023  

    Abstract: Recent advances in noninvasive portable and wearable biosensors have attracted significant attention due to their capability to offer continual physiological information for continuous healthcare monitoring through the collection of biological signals. ... ...

    Abstract Recent advances in noninvasive portable and wearable biosensors have attracted significant attention due to their capability to offer continual physiological information for continuous healthcare monitoring through the collection of biological signals. To make the collected biological data understandable and improve the efficacy of these biosensors, scientists have integrated machine learning (ML) with biosensors to analyze large sensing data through various ML algorithms. In this article, we have highlighted the recent developments in ML-enabled noninvasive biosensors. Initially, we introduced and discussed the basic features of ML algorithms used in data processing to build an intelligent biosensor system and the capability to make clinical decisions. Next, the principles of portable and wearable biosensors, the application of different ML models in diverse biosensors for healthcare applications, and their impact on the performance of biosensors are discussed. The last section highlights the challenges (such as data privacy, consistency, stability, accuracy, scalable production, and adaptive learning capacity), future prospects, and necessary steps required to address these issues, spotlighting their revolutionizing impact on the healthcare industry for the development of next-generation ML-enabled efficient biosensors.
    Keywords Machine learning ; Clinical decision making ; Portable and wearable biosensors ; Analytical chemistry ; QD71-142
    Subject code 006
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Airport smoking zones as a potential public health hazard- Correspondence.

    Singh, Ravinder / Singh, Manjinder / Singh, Varinder / Kumari, Pratima / Chopra, Hitesh / Priyanka / Choudhary, Om Prakash

    International journal of surgery (London, England)

    2023  

    Language English
    Publishing date 2023-03-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1097/JS9.0000000000000120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Impact of lockdown on air quality over major cities across the globe during COVID-19 pandemic.

    Kumari, Pratima / Toshniwal, Durga

    Urban climate

    2020  Volume 34, Page(s) 100719

    Abstract: In present study, the variation in concentration of key air pollutants such ... ...

    Abstract In present study, the variation in concentration of key air pollutants such as
    Keywords covid19
    Language English
    Publishing date 2020-10-16
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2212-0955
    ISSN (online) 2212-0955
    DOI 10.1016/j.uclim.2020.100719
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: GeMemiOM: the curated database on genes, putative methylation study targets, and microRNA targets for otitis media.

    Abhishek, Kondyarpu / Mohanta, Bineet Kumar / Kumari, Pratima / Dixit, Anshuman / Ramchander, Puppala Venkat

    Journal of genetics and genomics = Yi chuan xue bao

    2023  Volume 51, Issue 2, Page(s) 260–263

    MeSH term(s) Humans ; MicroRNAs/genetics ; Otitis Media/genetics ; Databases, Factual ; Protein Processing, Post-Translational ; Methylation
    Chemical Substances MicroRNAs
    Language English
    Publishing date 2023-08-02
    Publishing country China
    Document type Letter
    ZDB-ID 2374568-X
    ISSN 1873-5533 ; 1673-8527
    ISSN (online) 1873-5533
    ISSN 1673-8527
    DOI 10.1016/j.jgg.2023.07.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Morphological changes in white blood cells in systemic inflammatory response syndrome (SIRS) with and without sepsis: An observational study.

    Sharma, Siddharth / Pratima, Kumari / Ambedkar, Shivlok Narayan / Kumar, Rajesh / Kundan, Meghraj

    Journal of family medicine and primary care

    2023  Volume 12, Issue 6, Page(s) 1179–1184

    Abstract: Background: This is an observational study which aims to research morphological changes of white blood cells in patients with Systemic Inflammatory Response Syndrome (SIRS) with and without sepsis and evaluate morphological changes in white blood cells ... ...

    Abstract Background: This is an observational study which aims to research morphological changes of white blood cells in patients with Systemic Inflammatory Response Syndrome (SIRS) with and without sepsis and evaluate morphological changes in white blood cells as predictors of sepsis.
    Methods: Patients aged 18 years or more with SIRS with sepsis and SIRS without sepsis were included and those with haematological disorders or pregnant patients were excluded. A total of 52 patients with SIRS with sepsis and 32 patients of SIRS without sepsis were included. Peripheral blood smear was prepared from the venous blood sample drawn. The presence of toxic granules, cytoplasmic vacuoles, and Dohle bodies in both cases of SIRS with sepsis without sepsis were assessed and it was compared with culture-positive sepsis and shock.
    Results: The difference in the presence of toxic granules (55.8% vs. 12.5%; p <0.001), cytoplasmic vacuoles (30.8% vs. 6.3%; p -0.012), and Dohle bodies (17.3% vs. 0%; p = 0.012) was significantly higher in the SIRS with sepsis group, compared to the SIRS without sepsis group. In the subgroup analysis of patients in the sepsis group, it was observed that patients with positive blood culture (9%) had a significantly higher proportion of toxic granules (100% vs. 51.1%; p=0.059), cytoplasmic vacuoles (40% vs. 29.8%; p=0.637) and Dohle bodies (40% vs. 14.9%; p=0.202). However, these differences were not statistically significant.
    Conclusion: Toxic granules and cytoplasmic vacuoles in the neutrophils of patients with SIRS with sepsis were found more frequently, compared to patients of SIRS without sepsis. Dohle bodies were found only in patients with sepsis and not in those with SIRS without sepsis.
    Language English
    Publishing date 2023-06-30
    Publishing country India
    Document type Journal Article
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_2512_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Anterior abdominal wall swelling as incarcerated Spigelian hernia in an elderly female: A diagnostic dilemma.

    Lamichhane, Samiksha / Kc, Suraj / Gupta, Rakesh Kumar / Khanal, Bhawani / Shah, Pratima Kumari

    Radiology case reports

    2024  Volume 19, Issue 7, Page(s) 2812–2815

    Abstract: Spigelian hernias are difficult to detect and palpate during physical examination due to their deeper location. They can be asymptomatic or present with acute complications such as incarceration, strangulation, or bowel obstruction. Here we present a ... ...

    Abstract Spigelian hernias are difficult to detect and palpate during physical examination due to their deeper location. They can be asymptomatic or present with acute complications such as incarceration, strangulation, or bowel obstruction. Here we present a case of a 58-year-old female with history of palpable swelling over the left iliac fossa region with abdominal distension. A computed tomography with oral contrast revealed features suggestive of incarcerated Spigelian hernia with small bowel obstruction, which was later managed with laparoscopic ventral hernia repair and repair of seromuscular tear of the small bowel. Computed tomography is the gold standard for diagnosing the condition and assessing bowel status. Conservative treatment is not effective due to the high likelihood of complications, and surgery is the mainstay of management. The approach to surgery depends on the patient's characteristics, the type of hernia, and the surgeon's experience. Mesh repair is advocated regardless of approach.
    Language English
    Publishing date 2024-04-24
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2024.03.068
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Serum versican as a potential biomarker in patients with uterine fibroids: A study from Eastern India.

    Jasti, Pratima / Kumari, Suchitra / Singh, Sweta / Anudeep, P P

    Journal of family medicine and primary care

    2023  Volume 12, Issue 8, Page(s) 1704–1709

    Abstract: Objective: Versican is a chondroitin sulphate proteoglycan with raised expression at site of inflammation, and uterine fibroids are associated with local inflammation. Hence, this study aimed to estimate serum Versican levels in pre-menopausal women ... ...

    Abstract Objective: Versican is a chondroitin sulphate proteoglycan with raised expression at site of inflammation, and uterine fibroids are associated with local inflammation. Hence, this study aimed to estimate serum Versican levels in pre-menopausal women with uterine fibroids to evaluate its diagnostic efficiency.
    Materials and methods: This case-control study included forty uterine fibroid cases and 40 healthy controls. Cases clinically evaluated with USG findings, that is number, location of fibroid and volume calculated by prolate ellipse formula a × b × c × 0.523 (a - height, b - width, c - depth). Biochemical investigations, that is serum Versican levels, were estimated by ELISA with total cholesterol, HDLc and LDLc. Triglycerides by fully automated chemistry analysers. Serum biochemical parameters were compared and correlated with volume of fibroid. Area under receiver operating characteristic curve was calculated along with cut-off value to determine diagnostic potential of Versican, differentiating women with fibroids.
    Results: In the present study, patients with fibroids had decreased levels of serum Versican (79.43 ± 18.60) as compared to healthy controls (101.81 ± 28.24,
    Conclusion: Serum Versican levels were found significantly lower in women with fibroid with a negative correlation with volume of fibroid uterus. Furthermore, extensive study would help in substantiating diagnostic potential of serum Versican in fibroid uterus patients.
    Language English
    Publishing date 2023-08-29
    Publishing country India
    Document type Journal Article
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_320_23
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  9. Article ; Online: ICAM-1 and VCAM-1: Gatekeepers in various inflammatory and cardiovascular disorders.

    Singh, Varinder / Kaur, Rupinder / Kumari, Pratima / Pasricha, Chirag / Singh, Ravinder

    Clinica chimica acta; international journal of clinical chemistry

    2023  Volume 548, Page(s) 117487

    Abstract: Leukocyte migration from the vascular compartment is critical fornormal lymphocyte recirculation in specific tissues and immune response in inflammatory locations. Leukocyte recruitment, migration to inflammatory areas, and targeting in the extravascular ...

    Abstract Leukocyte migration from the vascular compartment is critical fornormal lymphocyte recirculation in specific tissues and immune response in inflammatory locations. Leukocyte recruitment, migration to inflammatory areas, and targeting in the extravascular space are caused by cellular stimulation and local expression of adhesion molecules. Intercellular adhesion molecule 1 (ICAM-1) and Vascular cell adhesion molecule 1 (VCAM-1) belong to the immunoglobulin superfamily of cell adhesion molecules (CAM) with a crucial role in mediating the strong adherence of leukocytes to endothelial cells in numerous acute as well as chronic diseases. ICAM-1 and VCAM-1 mediate inflammation and promote leukocyte migration during inflammation. ICAM-1 and VCAM-1 have a large role in regulating homeostasis and in pathologic states such as cancer, atherosclerosis, atrial fibrillation, myocardial infarction, stroke, asthma, obesity, kidney diseases, and much more. In inflammatory conditions and infectious disorders, leukocytes move and cling to the endothelium via multiple intracellular adhesive interactions. It is suggested that combining membrane-bound and soluble ICAM-1 and VCAM-1 into a single unit functional system will further our understanding of their immunoregulatory role as well as their pathophysiological effects on disease. This review focuses on the pathophysiological roles of ICAM-1 and VCAM-1 in various inflammatory and other diseases as well as their emerging cardiovascular role during the COVID-19 pandemic.
    MeSH term(s) Humans ; Cell Adhesion Molecules ; COVID-19 ; Endothelial Cells/metabolism ; Endothelium, Vascular ; Inflammation/metabolism ; Intercellular Adhesion Molecule-1/metabolism ; Pandemics ; Vascular Cell Adhesion Molecule-1/metabolism ; Cardiovascular Diseases/metabolism
    Chemical Substances Cell Adhesion Molecules ; Intercellular Adhesion Molecule-1 (126547-89-5) ; Vascular Cell Adhesion Molecule-1
    Language English
    Publishing date 2023-07-11
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 80228-1
    ISSN 1873-3492 ; 0009-8981
    ISSN (online) 1873-3492
    ISSN 0009-8981
    DOI 10.1016/j.cca.2023.117487
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  10. Article: Oral Potentially Malignant Disorders: Etiology, Pathogenesis, and Transformation Into Oral Cancer.

    Kumari, Pratima / Debta, Priyanka / Dixit, Anshuman

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 825266

    Abstract: Among oral diseases, oral cancer is a critical health issue due to its life-threatening potential. Globocan, in its 2020 report, estimated ∼0.37 million new cases of oral cancer, with the majority of them coming from the Asian continent. The WHO has ... ...

    Abstract Among oral diseases, oral cancer is a critical health issue due to its life-threatening potential. Globocan, in its 2020 report, estimated ∼0.37 million new cases of oral cancer, with the majority of them coming from the Asian continent. The WHO has anticipated a rise in the incidences of oral cancer in the coming decades. Various factors, such as genetic, epigenetic, microbial, habitual, and lifestyle factors, are closely associated with oral cancer occurrence and progression. Oral lesions, inherited genetic mutations (dyskeratosis congenital syndrome), and viral infections (HPV) are early signs of oral cancer. Lesions with dysplastic features have been categorized under oral potentially malignant disorders (OPMDs), such as oral leukoplakia, erythroplakia, oral submucous fibrosis (OSMF), and proliferative verrucous leukoplakia, are assumed to have a high risk of malignancy. The incidence and prevalence of OPMDs are recorded as being high in South-Asian countries. Early detection, prevention, and treatment of OPMDs are needed to prevent its malignant transformation into oral cancer. Many advanced diagnostic techniques are used to predict their progression and to assess the risk of malignant transformation. This communication provides insight into the importance of early detection and prevention of OPMDs.
    Language English
    Publishing date 2022-04-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.825266
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