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Article: Teachers' Emotional Intelligence, Burnout, Work Engagement, and Self-Efficacy during COVID-19 Lockdown.

Geraci, Alessandro / Di Domenico, Laura / Inguglia, Cristiano / D'Amico, Antonella

Behavioral sciences (Basel, Switzerland)

2023 Volume 13, Issue 4

Abstract: Teachers' psychological well-being is a crucial aspect that influences learning in a classroom climate. The aim of the study was to investigate teachers' emotional intelligence, burnout, work engagement, and self-efficacy in times of remote teaching ... ...

Abstract	Teachers' psychological well-being is a crucial aspect that influences learning in a classroom climate. The aim of the study was to investigate teachers' emotional intelligence, burnout, work engagement, and self-efficacy in times of remote teaching during COVID-19 lockdown. A sample of 65 teachers (M
Language	English
Publishing date	2023-03-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2651997-5
ISSN	2076-328X
ISSN	2076-328X
DOI	10.3390/bs13040296
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Limited data on infectious disease distribution exposes ambiguity in epidemic modeling choices

Di Domenico, Laura / Valdano, Eugenio / Colizza, Vittoria

2024

Abstract: Traditional disease transmission models assume that the infectious period is exponentially distributed with a recovery rate fixed in time and across individuals. This assumption provides analytical and computational advantages, however it is often ... ...

Abstract	Traditional disease transmission models assume that the infectious period is exponentially distributed with a recovery rate fixed in time and across individuals. This assumption provides analytical and computational advantages, however it is often unrealistic. Efforts in modeling non-exponentially distributed infectious periods are either limited to special cases or lead to unsolvable models. Also, the link between empirical data (infectious period distribution) and the modeling needs (corresponding recovery rates) lacks a clear understanding. Here we introduce a mapping of an arbitrary distribution of infectious periods into a distribution of recovery rates. We show that the same infectious period distribution at the population level can be reproduced by two modeling schemes -- host-based and population-based -- depending on the individual response to the infection, and aggregated empirical data cannot easily discriminate the correct scheme. Besides being conceptually different, the two schemes also lead to different epidemic trajectories. Although sharing the same behavior close to the disease-free equilibrium, the host-based scheme deviates from the expected epidemic when reaching the endemic equilibrium of an SIS transmission model, while the population-based scheme turns out to be equivalent to assuming a homogeneous recovery rate. We show this through analytical computations and stochastic epidemic simulations on a contact network, using both generative network models and empirical contact data. It is therefore possible to reproduce heterogeneous infectious periods in network-based transmission models, however the resulting prevalence is sensitive to the modeling choice for the interpretation of the empirically collected data on infection duration. In absence of higher resolution data, studies should acknowledge such deviations in the epidemic predictions.
Keywords	Quantitative Biology - Populations and Evolution ; Physics - Physics and Society
Subject code	612
Publishing date	2024-01-26
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The impact of spatial connectivity on NPIs effectiveness.

Sabbatini, Chiara E / Pullano, Giulia / Di Domenico, Laura / Rubrichi, Stefania / Bansal, Shweta / Colizza, Vittoria

BMC infectious diseases

2024 Volume 24, Issue 1, Page(s) 21

Abstract: Background: France implemented a combination of non-pharmaceutical interventions (NPIs) to manage the COVID-19 pandemic between September 2020 and June 2021. These included a lockdown in the fall 2020 - the second since the start of the pandemic - to ... ...

Abstract	Background: France implemented a combination of non-pharmaceutical interventions (NPIs) to manage the COVID-19 pandemic between September 2020 and June 2021. These included a lockdown in the fall 2020 - the second since the start of the pandemic - to counteract the second wave, followed by a long period of nighttime curfew, and by a third lockdown in the spring 2021 against the Alpha wave. Interventions have so far been evaluated in isolation, neglecting the spatial connectivity between regions through mobility that may impact NPI effectiveness. Methods: Focusing on September 2020-June 2021, we developed a regionally-based epidemic metapopulation model informed by observed mobility fluxes from daily mobile phone data and fitted the model to regional hospital admissions. The model integrated data on vaccination and variants spread. Scenarios were designed to assess the impact of the Alpha variant, characterized by increased transmissibility and risk of hospitalization, of the vaccination campaign and alternative policy decisions. Results: The spatial model better captured the heterogeneity observed in the regional dynamics, compared to models neglecting inter-regional mobility. The third lockdown was similarly effective to the second lockdown after discounting for immunity, Alpha, and seasonality (51% vs 52% median regional reduction in the reproductive number R Conclusions: Spatial connectivity induced by mobility impacted the effectiveness of interventions especially in regions with higher mobility rates. Early evening curfew with gastronomy sector closed allowed authorities to delay the third wave. Stop-and-go lockdowns could have substantially lowered both healthcare and societal burdens if implemented early enough, compared to the observed application of lockdown-curfew-lockdown, but likely at the expense of several labor sectors. These findings contribute to characterize the effectiveness of implemented strategies and improve pandemic preparedness.
MeSH term(s)	Humans ; Pandemics/prevention & control ; COVID-19/epidemiology ; COVID-19/prevention & control ; Cell Phone ; France/epidemiology ; Health Facilities
Language	English
Publishing date	2024-01-02
Publishing country	England
Document type	Journal Article
ZDB-ID	2041550-3
ISSN	1471-2334 ; 1471-2334
ISSN (online)	1471-2334
ISSN	1471-2334
DOI	10.1186/s12879-023-08900-x
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Article: Soft Tissue Substitutes in Periodontal and Peri-Implant Soft Tissue Augmentation: A Systematic Review.

Rotundo, Roberto / Pancrazi, Gian Luca / Grassi, Alessia / Ceresoli, Lara / Di Domenico, Giovanna Laura / Bonafede, Vanessa

Materials (Basel, Switzerland)

2024 Volume 17, Issue 5

Abstract: Background: Different extracellular matrix (ECM)-based technologies in periodontal and peri-implant soft tissue augmentation have been proposed in the market. The present review compared the efficacy of soft tissue substitutes (STSs) and autogenous free ...

Abstract	Background: Different extracellular matrix (ECM)-based technologies in periodontal and peri-implant soft tissue augmentation have been proposed in the market. The present review compared the efficacy of soft tissue substitutes (STSs) and autogenous free gingival grafts (FGGs) or connective tissue grafts (CTGs) in mucogingival procedures to increase keratinized tissue (KT) width around teeth and implants. Methods: Two independent examiners performed an electronic search on MEDLINE and the Cochrane Library based on the following PICOS format: (P) adult patients; (I) soft tissue substitutes and FGGs/CTGs; (C) STSs vs. CTGs; STSs vs. FGGs; STSs vs control; (O) KT width gain; (S) systematic reviews, randomized controlled trials. Studies published before November 2023 were included. Results: Around teeth, all biomaterials showed superior performance compared to a coronally advanced flap (CAF) alone for treating gingival recessions. However, when compared to CTGs, acellular dermal matrices (ADMs) yield the most similar outcomes to the gold standard (CTGs), even though in multiple recessions, CTGs continue to be considered the most favorable approach. The use of STSs (acellular matrix or tissue-engineered) in combination with apically positioned flaps (APF) resulted in significantly less gain in KT width compared to that achieved with FGGs and APFs. Around dental implants, free gingival grafts were deemed more effective than soft tissue substitutes in enhancing keratinized mucosa width. Conclusions: Based on the available evidence, questions remain about the alternative use of soft tissue substitutes for conventional grafting procedures using free gingival grafts or connective tissue grafts around teeth and implants.
Language	English
Publishing date	2024-03-06
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma17051221
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Article ; Online: Multiple coronally advanced flap with a selective use of connective tissue graft: A 3-year prospective clinical and histological study.

Di Domenico, Giovanna Laura / Di Martino, Maria / Arrigoni, Gianluigi / Aroca, Sofia / de Sanctis, Massimo

Journal of periodontology

2023 Volume 94, Issue 10, Page(s) 1200–1209

Abstract: Background: The purpose of the present study was to prospectively evaluate the 3-year changes in the gingival dimensions following multiple coronally advanced flap (MCAF) with selective use of connective tissue graft (CTG). In addition, the secondary ... ...

Abstract	Background: The purpose of the present study was to prospectively evaluate the 3-year changes in the gingival dimensions following multiple coronally advanced flap (MCAF) with selective use of connective tissue graft (CTG). In addition, the secondary aim was to histologically identify the factors related to phenotype changes. Methods: Twenty patients treated with MCAF and site-specific application of a CTG were available for the 3-year follow-up. Outcome measures included complete root coverage (CRC), recession reduction, keratinized tissue width (KTW), marginal tissue thickness changes, and primary flap position. Biopsies were harvested at one of the sites treated with the adjunct of CTG. All sections were stained with hematoxylin and eosin, Masson trichrome, Verhoeff-van Gieson, tenascin, and alcian blue stain for semiquantitative evaluation. Results: At 3 years, CRC was detected in 86% of sites treated with MCAF alone and 81% of sites treated with MCAF + CTG. The 47% of sites treated with MCAF + CTG presented an apical shift of primary flap from its original position. Linear regression showed a significant association between KTW change and the initial KTW in MCAF-treated sites, while both initial KTW and position of primary flap were statistically significantly associated factors with KTW changes in the MCAF + CTG group. In all the biopsies examined, there is always a marked and clear separation between the connective tissue of the gingival flap and the palatal connective tissue of the graft. Conclusions: The selective use of CTG is an effective treatment for multiple gingival recessions. Only a limited increase in KTW can be expected in a bilaminar technique if, during the healing phases, the connective tissue is maintained completely covered.
MeSH term(s)	Humans ; Prospective Studies ; Tooth Root/surgery ; Gingiva/transplantation ; Gingival Recession/surgery ; Connective Tissue/transplantation ; Treatment Outcome
Language	English
Publishing date	2023-04-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	390921-9
ISSN	1943-3670 ; 0022-3492 ; 1049-8885 ; 0095-960X
ISSN (online)	1943-3670
ISSN	0022-3492 ; 1049-8885 ; 0095-960X
DOI	10.1002/JPER.22-0632
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Article: SEM Evaluation of the Marginal Accuracy of Zirconia, Lithium Disilicate, and Composite Single Crowns Created by CAD/CAM Method: Comparative Analysis of Different Materials.

Ferrini, Francesco / Paolone, Gaetano / Di Domenico, Giovanna Laura / Pagani, Nicolò / Gherlone, Enrico Felice

Materials (Basel, Switzerland)

2023 Volume 16, Issue 6

Abstract: 1) Background: The objective of this in vitro study is to evaluate the marginal accuracy of crowns created by CAD/CAM. (2) Methods: A customized chrome-cobalt (Cr-Co) implant abutment simulating a maxillary right first molar was fixed in a hemi- ... ...

Abstract	(1) Background: The objective of this in vitro study is to evaluate the marginal accuracy of crowns created by CAD/CAM. (2) Methods: A customized chrome-cobalt (Cr-Co) implant abutment simulating a maxillary right first molar was fixed in a hemi-maxillary stone model and scanned. In total, 27 crowns were fabricated, including 9 lithium disilicate crowns, 9 composite crowns, and 9 zirconia crowns. The measurements were determined by scanning electron microscopy. Descriptive analysis was performed using the mean and standard deviation, while the Kruskal-Wallis test was performed to determine whether the marginal discrepancies were significantly different between each group (
Language	English
Publishing date	2023-03-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma16062413
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Article ; Online: Treatment of multiple adjacent gingival recessions with coronally advanced flap versus modified coronally advanced tunnel with a volumetrically stable collagen matrix: a 12-months randomized controlled clinical trial.

Di Domenico, Giovanna Laura / Guglielmi, Davide / Aroca, Sofia / de Sanctis, Massimo

The International journal of periodontics & restorative dentistry

2023

Abstract: Objective: The introduction of a new collagen substitute, that potentially will reduce the invasiveness of the two techniques, by avoiding the need for a second surgical site, i.e., the donor site, need to be evaluated in relation with the surgical ... ...

Abstract	Objective: The introduction of a new collagen substitute, that potentially will reduce the invasiveness of the two techniques, by avoiding the need for a second surgical site, i.e., the donor site, need to be evaluated in relation with the surgical procedure that could benefit the most by the utilization of such a matrix. The aim of this study was to compare the clinical outcomes following treatment of RT 1 multiple adjacent gingival recessions (MAGRs) using the modified coronally advanced tunnel technique (MCAT) or the multiple coronally advanced flap (MCAF) in conjunction with a new volume stable xenogeneic collagen matrix (VXCM). Secondarily, the study evaluated whether patients report a preference in terms of discomfort between the two surgical techniques. Methods: Twenty patients requiring treatment of MAGRs were randomly assigned to one of the two treatment groups (group A: MCAF+VCMX; group B: MCAT+VCMX). The following measurements were recorded at baseline (i.e. prior to surgery), at 6 and 12 months: gingival recession depth (REC), probing pocket depth (PPD), keratinized tissue width (KTW) and gingival thickness (GT). Post-operative pain and discomfort were recorded using a visual analogue scale (VAS) at 1 week. The primary outcome variable was mean root coverage (mRC), secondary outcomes were complete root coverage (CRC), change in KTW and GT, patient discomfort and satisfaction, and duration of surgery. Results: Healing was uneventful in both groups. At 12 months, both treatments resulted in statistically significant improvements of REC and GT compared with baseline (p < 0.05). The mRC measured 79.95 ± 29.92% at MCAF group, whereas 64.74 ± 40.5% MCAT group (p = 0.124). CRC was found at 65.6% of MCAF-treated sites and at 52% of MCAT-treated sites (p=0.181). Conclusions: Similar clinical results should be expected when MAGRs are treated with MCAF or MCAT, with the adjunct of VCMX.
Language	English
Publishing date	2023-07-20
Publishing country	United States
Document type	Journal Article
ISSN	1945-3388
ISSN (online)	1945-3388
DOI	10.11607/prd.6796
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Dental Restorations.

Mandurino, Mauro / Di Domenico, Giovanna Laura / Baldani, Sofia / Collivasone, Giacomo / Gherlone, Enrico Felice / Cantatore, Giuseppe / Paolone, Gaetano

Bioengineering (Basel, Switzerland)

2023 Volume 10, Issue 7

Abstract: Fulfilling a patient's request for a healthy, functional and esthetic smile represents a daily challenge for dental practitioners [ ... ]. ...

Abstract	Fulfilling a patient's request for a healthy, functional and esthetic smile represents a daily challenge for dental practitioners [...].
Language	English
Publishing date	2023-07-10
Publishing country	Switzerland
Document type	Editorial
ZDB-ID	2746191-9
ISSN	2306-5354
ISSN	2306-5354
DOI	10.3390/bioengineering10070820
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Article ; Online: Retraction notice to "Glycogen synthase kinase-3β inhibition attenuates the degree of arthritis caused by type II collagen in the mouse" [Clin. Immunol. 120/1 (2006) 57-67].

Cuzzocrea, Salvatore / Mazzon, Emanuela / Di Paola, Rosanna / Muià, Carmelo / Crisafulli, Concetta / Dugo, Laura / Collin, Marika / Britti, Domenico / Caputi, Achille P / Thiemermann, Christoph

Clinical immunology (Orlando, Fla.)

2024 Volume 262, Page(s) 110198

Language	English
Publishing date	2024-03-29
Publishing country	United States
Document type	Journal Article ; Retraction of Publication
ZDB-ID	1459903-x
ISSN	1521-7035 ; 1521-6616
ISSN (online)	1521-7035
ISSN	1521-6616
DOI	10.1016/j.clim.2024.110198
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Article: The Pharmaceutical Formulation Plays a Pivotal Role in Hydroxytyrosol Pharmacokinetics.

Di Renzo, Laura / Smeriglio, Antonella / Ingegneri, Mariarosaria / Gualtieri, Paola / Trombetta, Domenico

Pharmaceutics

2023 Volume 15, Issue 3

Abstract: Current evidence supports the use of extra virgin olive oil (EVOO) and its minor components such as hydroxytyrosol or 3,4-dihydroxyphenyl ethanol (DOPET), to improve cardiovascular and metabolic health. Nevertheless, more intervention studies in humans ... ...

Abstract	Current evidence supports the use of extra virgin olive oil (EVOO) and its minor components such as hydroxytyrosol or 3,4-dihydroxyphenyl ethanol (DOPET), to improve cardiovascular and metabolic health. Nevertheless, more intervention studies in humans are needed because some gaps remain in its bioavailability and metabolism. The aim of this study was to investigate the DOPET pharmacokinetics on 20 healthy volunteers by administering a hard enteric-coated capsule containing 7.5 mg of bioactive compound conveyed in EVOO. The treatment was preceded by a washout period with a polyphenol and an alcohol-free diet. Blood and urine samples were collected at baseline and different time points, and free DOPET and metabolites, as well as sulfo- and glucuro-conjugates, were quantified by LC-DAD-ESI-MS/MS analysis. The plasma concentration versus time profiles of free DOPET was analyzed by a non-compartmental approach, and several pharmacokinetic parameters (C
Language	English
Publishing date	2023-02-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527217-2
ISSN	1999-4923
ISSN	1999-4923
DOI	10.3390/pharmaceutics15030743
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