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  1. Article: Study UNICO: Perception of Urologists and Andrologists, in Spain, about the Use of Sildenafil Oral Suspension in Patients with Erectile Dysfunction.

    Peinado Ibarra, François / García Gómez, Borja / Luján Marco, Saturnino / Segura Paños, Ana María

    Archivos espanoles de urologia

    2023  Volume 76, Issue 2, Page(s) 139–144

    Abstract: Objective: To describe the profile of patients with erectile dysfunction (ED), attending to consultation and satisfaction using sildenafil oral suspension, from the specialist's perception.: Materials and methods: This is a nationwide multicenter, ... ...

    Abstract Objective: To describe the profile of patients with erectile dysfunction (ED), attending to consultation and satisfaction using sildenafil oral suspension, from the specialist's perception.
    Materials and methods: This is a nationwide multicenter, epidemiological, descriptive and observational study, with the studied population as the unit of study. Thirty urologists and/or andrologists completed a questionnaire with questions about ED patients' profile attending to their practice, sildenafil oral suspension perception of effectiveness and safeness, and their opinion about patients' satisfaction after sildenafil oral suspension treatment. Aggregate data were collected for the last 6 patients treated or on treatment with sildenafil oral suspension.
    Results: Overall, 40.9% and 24.9% of patients had moderate or severe ED, respectively. Among the patients, 73.6% were older than 50 years. The disease progression was approximately one year (11.8 months). ED etiology was mostly organic (38.1%) and mixed (31.8%). Cardiovascular comorbidities were present in 57.4%, mental health problems in 16.4% and hormonal disorders in 10.2% of the patients. The main reason for choosing sildenafil oral suspension was the ease of dose adjustment. The specialists considered that 73.4% of the patients responded satisfactorily to treatment. They also rated the perceived effectiveness and safeness of the product as very good or good.
    Conclusions: Urologists and andrologists consider that most patients with ED achieve a high degree of satisfaction with sildenafil oral suspension. The main advantage of the treatment is the possibility of adjusting the dose according to patient's needs and circumstances.
    MeSH term(s) Male ; Humans ; Sildenafil Citrate/therapeutic use ; Erectile Dysfunction/drug therapy ; Spain ; Urologists ; Piperazines/adverse effects ; Purines/therapeutic use ; Patient Satisfaction ; Surveys and Questionnaires ; Perception ; Treatment Outcome
    Chemical Substances Sildenafil Citrate (BW9B0ZE037) ; Piperazines ; Purines
    Language English
    Publishing date 2023-04-17
    Publishing country Spain
    Document type Observational Study ; Multicenter Study ; Journal Article
    ZDB-ID 211673-x
    ISSN 0004-0614
    ISSN 0004-0614
    DOI 10.56434/j.arch.esp.urol.20237602.15
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Impact of the COVID-19 pandemic on the sexual behavior of the population. The vision of the east and the west.

    Ibarra, François Peinado / Mehrad, Mehri / Di Mauro, Marina / Godoy, María Fernanda Peraza / Cruz, Eduard García / Nilforoushzadeh, Mohammad Ali / Russo, Giorgio Ivan

    International braz j urol : official journal of the Brazilian Society of Urology

    2020  Volume 46, Issue suppl.1, Page(s) 104–112

    Abstract: The COVID-19 pandemic has radically changed the way of life around the World. The state of alarm has forced the population to stay at home, radically changing both interpersonal and partner relationships; work at home, social distancing, the continued ... ...

    Abstract The COVID-19 pandemic has radically changed the way of life around the World. The state of alarm has forced the population to stay at home, radically changing both interpersonal and partner relationships; work at home, social distancing, the continued presence of children at home, fear of infection and not being able to physically meet with others have changed most people's sexual habits. We conducted a review by exploring the impact of the COVID-19 pandemic on sexual behavior in the population from three different countries: Iran, Italy and Spain from each country's perspective. The impact of the coronavirus will be very important in the sexual life of the people and we will attend in the next months or years, to some changes in the relationships at all the levels. The pandemic will negatively affect sexual behaviors due to multiple contact restrictions. In the future, we will be able to assess these effects in more detail.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Humans ; Iran ; Italy ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Sexual Behavior ; Spain
    Keywords covid19
    Language English
    Publishing date 2020-04-14
    Publishing country Brazil
    Document type Journal Article ; Review
    ZDB-ID 2206649-4
    ISSN 1677-6119 ; 1677-5538
    ISSN (online) 1677-6119
    ISSN 1677-5538
    DOI 10.1590/S1677-5538.IBJU.2020.S116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Impact of the COVID-19 pandemic on the sexual behavior of the population. The vision of the east and the west

    Ibarra, François Peinado / Mehrad, Mehri / Di Mauro, Marina / Godoy, María Fernanda Peraza / Cruz, Eduard García / Nilforoushzadeh, Mohammad Ali / Russo, Giorgio Ivan

    Int Braz J Urol

    Abstract: The COVID-19 pandemic has radically changed the way of life around the World. The state of alarm has forced the population to stay at home, radically changing both interpersonal and partner relationships; work at home, social distancing, the continued ... ...

    Abstract The COVID-19 pandemic has radically changed the way of life around the World. The state of alarm has forced the population to stay at home, radically changing both interpersonal and partner relationships; work at home, social distancing, the continued presence of children at home, fear of infection and not being able to physically meet with others have changed most people's sexual habits. We conducted a review by exploring the impact of the COVID-19 pandemic on sexual behavior in the population from three different countries: Iran, Italy and Spain from each country's perspective. The impact of the coronavirus will be very important in the sexual life of the people and we will attend in the next months or years, to some changes in the relationships at all the levels. The pandemic will negatively affect sexual behaviors due to multiple contact restrictions. In the future, we will be able to assess these effects in more detail.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #603712
    Database COVID19

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  4. Article ; Online: Impact of the COVID-19 pandemic on the sexual behavior of the population. The vision of the east and the west

    Ibarra, François Peinado / Mehrad, Mehri / Mauro, Marina Di / Godoy, Maria Fernanda Peraza / Cruz, Eduard García / Nilforoushzadeh, Mohammad Ali / Russo, Giorgio Ivan

    2020  

    Abstract: ... n/ ... ...

    Abstract n/a
    Keywords Urology ; covid19
    Language Undetermined
    Publishing date 2020-07-27
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Multicenter Prospective Study of Grafting With Collagen Fleece TachoSil in Patients With Peyronie's Disease.

    Fernández-Pascual, Esaú / Manfredi, Celeste / Torremadé, Jose / Ibarra, François Peinado / Geli, Joaquim Sarquella / Romero-Otero, Javier / García-Baquero, Rodrigo / Poblador, Agustín Fraile / Barbará, Mariano Roselló / Campos-Juanatey, Félix / Rojo, Alejandra Egui / Iribarren, Ignacio Moncada / Rodríguez, Joaquín Carballido / Martínez-Salamanca, Juan Ignacio

    The journal of sexual medicine

    2020  Volume 17, Issue 11, Page(s) 2279–2286

    Abstract: Background: A xenograft consisting of equine collagen coated with human fibrinogen and thrombin (TachoSil; Baxter, CA) has recently been introduced in grafting procedures for Peyronie's disease (PD).: Aim: To describe the results of a multicenter ... ...

    Abstract Background: A xenograft consisting of equine collagen coated with human fibrinogen and thrombin (TachoSil; Baxter, CA) has recently been introduced in grafting procedures for Peyronie's disease (PD).
    Aim: To describe the results of a multicenter prospective registry on patients with PD undergoing plaque incision or and grafting (PIG) or plaque excision and grafting (PEG) with collagen fleece TachoSil, to evaluate the efficacy and safety of this procedure.
    Methods: A prospective non-controlled multicenter study of patients with PD was performed between May 2016 and March 2018. Patients from 10 centers with stable PD for at least 3 months, difficulties in sexual intercourse, normal erectile function with or without pharmacological treatment, curvature >45°, and/or penile shortening and/or complex deformities were included. All patients underwent PIG/PEG with collagen fleece TachoSil.
    Outcomes: The main outcome measure of this study were penile curvature correction (intraoperative), penile shortening (intraoperative), erectile function with the 5-item version of the International Index of Erectile Function (IIEF-5) and the Erection Hardness Score, subjective patient outcomes with non-validated questionnaires, and complications.
    Results: A total of 52 patients were enrolled in the study. The mean (SD) preoperative penile curvature was 72.8° (17.0). PIG was the preferred technique (80.8%). Intraoperatively, complete curvature correction was achieved in 92.3%, and no significant penile shortening was recorded in 80.8% of subjects. Subjective penile shortening was reported in 83.3% of patients at 6 months. No objective measurement of penile curvature and length was recorded during follow-up. No statistically significant difference from the baseline was found in IIEF-5 and Erection Hardness Score at 3 or at 6 months, although 16.7% of men experienced a worsening of IIEF-5 scores and 14.3% required de novo phosphodiesterase type 5 inhibitor use. 6 months after surgery, 78.5% of men were satisfied with intervention. Swelling and ecchymosis/hematoma were the most common perioperative complications (40.4%). 2 cases (3.8%) of wound infection were recorded. At 6 months, 35.7% of patients reported mild penile hypesthesia.
    Clinical implications: Our results confirm the high success rate of grafting with TachoSil, and the surgeon perceived low percentage of penile shortening.
    Strength & limitations: This is the first multicentre study on patients with PD undergoing grafting with TachoSil without concomitant placement of penile prosthesis. The main limitations are the short follow-up and the relatively small sample size.
    Conclusion: Grafting with TachoSil after PIG/PEG in patients with PD is an effective and safe procedure. Among the main advantages of this technique, there are ease of use of the graft and reduced operative time. Fernández-Pascual E, Manfredi C, Torremadé J, et al. Multicenter Prospective Study of Grafting With Collagen Fleece TachoSil in Patients With Peyronie's Disease. J Sex Med 2020;17:2279-2286.
    MeSH term(s) Animals ; Collagen ; Drug Combinations ; Fibrinogen/therapeutic use ; Horses ; Humans ; Male ; Patient Satisfaction ; Penile Induration/surgery ; Penis ; Prospective Studies ; Thrombin ; Treatment Outcome
    Chemical Substances Drug Combinations ; TachoSil ; Fibrinogen (9001-32-5) ; Collagen (9007-34-5) ; Thrombin (EC 3.4.21.5)
    Keywords covid19
    Language English
    Publishing date 2020-08-20
    Publishing country Netherlands
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2251959-2
    ISSN 1743-6109 ; 1743-6095
    ISSN (online) 1743-6109
    ISSN 1743-6095
    DOI 10.1016/j.jsxm.2020.07.079
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Multicenter Prospective Study of Grafting With Collagen Fleece TachoSil in Patients With Peyronie's Disease

    Fernández-Pascual, Esaú / Manfredi, Celeste / Torremadé, Jose / Ibarra, François Peinado / Geli, Joaquim Sarquella / Romero-Otero, Javier / García-Baquero, Rodrigo / Poblador, Agustín Fraile / Barbará, Mariano Roselló / Campos-Juanatey, Félix / Rojo, Alejandra Egui / Iribarren, Ignacio Moncada / Rodríguez, Joaquín Carballido / Martínez-Salamanca, Juan Ignacio

    J. sex. med

    Abstract: BACKGROUND: A xenograft consisting of equine collagen coated with human fibrinogen and thrombin (TachoSil; Baxter, CA) has recently been introduced in grafting procedures for Peyronie's disease (PD). AIM: To describe the results of a multicenter ... ...

    Abstract BACKGROUND: A xenograft consisting of equine collagen coated with human fibrinogen and thrombin (TachoSil; Baxter, CA) has recently been introduced in grafting procedures for Peyronie's disease (PD). AIM: To describe the results of a multicenter prospective registry on patients with PD undergoing plaque incision or and grafting (PIG) or plaque excision and grafting (PEG) with collagen fleece TachoSil, to evaluate the efficacy and safety of this procedure. METHODS: A prospective non-controlled multicenter study of patients with PD was performed between May 2016 and March 2018. Patients from 10 centers with stable PD for at least 3 months, difficulties in sexual intercourse, normal erectile function with or without pharmacological treatment, curvature >45°, and/or penile shortening and/or complex deformities were included. All patients underwent PIG/PEG with collagen fleece TachoSil. OUTCOMES: The main outcome measure of this study were penile curvature correction (intraoperative), penile shortening (intraoperative), erectile function with the 5-item version of the International Index of Erectile Function (IIEF-5) and the Erection Hardness Score, subjective patient outcomes with non-validated questionnaires, and complications. RESULTS: A total of 52 patients were enrolled in the study. The mean (SD) preoperative penile curvature was 72.8° (17.0). PIG was the preferred technique (80.8%). Intraoperatively, complete curvature correction was achieved in 92.3%, and no significant penile shortening was recorded in 80.8% of subjects. Subjective penile shortening was reported in 83.3% of patients at 6 months. No objective measurement of penile curvature and length was recorded during follow-up. No statistically significant difference from the baseline was found in IIEF-5 and Erection Hardness Score at 3 or at 6 months, although 16.7% of men experienced a worsening of IIEF-5 scores and 14.3% required de novo phosphodiesterase type 5 inhibitor use. 6 months after surgery, 78.5% of men were satisfied with intervention. Swelling and ecchymosis/hematoma were the most common perioperative complications (40.4%). 2 cases (3.8%) of wound infection were recorded. At 6 months, 35.7% of patients reported mild penile hypesthesia. CLINICAL IMPLICATIONS: Our results confirm the high success rate of grafting with TachoSil, and the surgeon perceived low percentage of penile shortening. STRENGTH & LIMITATIONS: This is the first multicentre study on patients with PD undergoing grafting with TachoSil without concomitant placement of penile prosthesis. The main limitations are the short follow-up and the relatively small sample size. CONCLUSION: Grafting with TachoSil after PIG/PEG in patients with PD is an effective and safe procedure. Among the main advantages of this technique, there are ease of use of the graft and reduced operative time. Fernández-Pascual E, Manfredi C, Torremadé J, et al. Multicenter Prospective Study of Grafting With Collagen Fleece TachoSil in Patients With Peyronie's Disease. J Sex Med 2020;XX:XXX-XXX.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32830078
    Database COVID19

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