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  1. AU=Das Ananya
  2. AU="Dave, Riya"
  3. AU=Kwon Okyu
  4. AU="Ortiz-López, Francisco Javier"
  5. AU="Churiwal, Mehal"
  6. AU="Nandi, Asoke K"
  7. AU="Fishchenko, I"
  8. AU="Yong, Ken-Tye"
  9. AU="Alexander, Regi T"
  10. AU=Weng Cheng-Hao
  11. AU="Christine Hamel"

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  1. Artikel ; Online: Awareness regarding oral cancer amongst the dental, medical, and nursing students: Is something lacking?

    Das, Rupsa / Misra, Satya Ranjan / Nayak, Ananya

    Oral oncology

    2024  Band 152, Seite(n) 106790

    Mesh-Begriff(e) Humans ; Mouth Neoplasms ; Students, Nursing/psychology ; Students, Medical/psychology ; Students, Dental/statistics & numerical data ; Students, Dental/psychology ; Health Knowledge, Attitudes, Practice ; Female ; Male
    Sprache Englisch
    Erscheinungsdatum 2024-04-03
    Erscheinungsland England
    Dokumenttyp Letter
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2024.106790
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Impact of the COVID-19 pandemic on the workflow of an ambulatory endoscopy center: an assessment by discrete event simulation.

    Das, Ananya

    Gastrointestinal endoscopy

    2020  Band 92, Heft 4, Seite(n) 914–924

    Abstract: Background and aims: As community-based ambulatory endoscopy centers (AECs) across the nation are trying to reopen and safely resume outpatient endoscopic procedures after the unprecedented lockdown related to the coronavirus disease 2019 (COVID-19) ... ...

    Abstract Background and aims: As community-based ambulatory endoscopy centers (AECs) across the nation are trying to reopen and safely resume outpatient endoscopic procedures after the unprecedented lockdown related to the coronavirus disease 2019 (COVID-19) pandemic, guidelines recommend pretesting and screening for COVID-19 along with other mitigation measures for the safety of patients and staff. The impact of such changes in the workflow of AECs on throughput and other performance indicators is largely unknown, although a significant reduction in revenue stream is expected.
    Methods: A discrete event simulation-based model was developed in the setting of a small to medium community-based single-specialty AEC to quantify the impact of COVID-19-related workflow changes on performance indicators and cost per case compared with the pre-COVID-19 baseline.
    Results: In the simulation model, post-COVID-19 recommended workflow changes significantly impacted the operational and productivity metrics and, in turn, adversely affected financial metrics. Overall, there was a significant decrease in staff utilization and consequent increase in total facility time, waiting time for patients, and cost per case because of a bottleneck at the time of preprocedure COVID-19 screening and testing while practicing social distancing. Strategies to minimize this adverse impact on productivity were assessed.
    Conclusions: Pretesting and screening for COVID-19 as recommended by current guidelines will significantly impact the productivity and revenue stream of AECs. Urgent measures by payors are needed to adjust the facility reimbursement of endoscopy centers to ensure successful reopening and ramping up outpatient endoscopy services in these facilities already hit hard by the pandemic.
    Mesh-Begriff(e) Ambulatory Care/organization & administration ; Ambulatory Care Facilities/organization & administration ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Endoscopy ; Humans ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; SARS-CoV-2 ; Workflow
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-06-10
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2020.06.008
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  3. Artikel ; Online: Landscape assessment of the cities in the state of Maharashtra: first step towards air quality management (AQM) and strategic implementation of mitigation plans.

    Das, Ananya / Ghosh, Arpita

    Environmental science and pollution research international

    2023  Band 30, Heft 21, Seite(n) 59233–59248

    Abstract: Objective of the study: This study aims to understand the need for landscape assessment of the 18 non-attainment cities in the state of Maharashtra, to understand and rank the cities according to the need and necessity for strategic implementation of ... ...

    Abstract Objective of the study: This study aims to understand the need for landscape assessment of the 18 non-attainment cities in the state of Maharashtra, to understand and rank the cities according to the need and necessity for strategic implementation of air quality management. This air quality management is a National Clean Air Programme initiative to curb the air pollution level in all the highly polluted Indian cities by 20-30% till 2024.
    Methodology: The ranking and selection of the cities consisted of a two-phase approach including (a) desk research and (b) field interventions and stakeholders' consultations. The first phase included (a
    Results and discussion: The screening of cities from the first phase gave a possible list of 8 cities-Aurangabad, Kolhapur, Mumbai, Nagpur, Nashik, Navi Mumbai, Pune, Solapur. Further, the second round of analysis involving field interventions and stakeholder consultations was done within the 8 cities to find out the most suitable list of two to 5 cities. The second research analysis gave Aurangabad, Kolhapur, Mumbai, Navi Mumbai and Pune. A more granular stakeholder consultation resulted in the selection of cities like Navi Mumbai and Pune as the cities where implementation of new strategies seemed feasible.
    Intervention and activities: New strategic interventions like (a) strengthen the clean air ecosystem/institutions, (b) air quality monitoring and health impact assessment, and (c) skill development to ensure the long-term sustainability of initiatives planned for the cities.
    Mesh-Begriff(e) Cities ; Ecosystem ; India ; Air Pollution/analysis ; Data Collection ; Air Pollutants/analysis
    Chemische Substanzen Air Pollutants
    Sprache Englisch
    Erscheinungsdatum 2023-03-31
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-023-26668-0
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Bonn

    Z 5915: Hefte anzeigen

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  4. Artikel ; Online: Knockdown Experiment Reveals an Essential GTPase CgtA's Involvement in Growth, Viability, Motility, Morphology, and Persister Phenotypes in Vibrio cholerae.

    Das, Sagarika / Chatterjee, Ananya / Datta, Partha Pratim

    Microbiology spectrum

    2023  , Seite(n) e0318122

    Abstract: CgtA is an essential bacterial GTPase consisting of a highly conserved N-terminal ... ...

    Abstract CgtA is an essential bacterial GTPase consisting of a highly conserved N-terminal Spo
    Sprache Englisch
    Erscheinungsdatum 2023-03-14
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.03181-22
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Impact of the COVID-19 pandemic on the workflow of an ambulatory endoscopy center

    Das, Ananya

    Gastrointestinal Endoscopy

    an assessment by discrete event simulation

    2020  Band 92, Heft 4, Seite(n) 914–924

    Schlagwörter Gastroenterology ; Radiology Nuclear Medicine and imaging ; covid19
    Sprache Englisch
    Verlag Elsevier BV
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2020.06.008
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel: A Critical evaluation of beneficial gut flora: probiotics, prebiotics postbiotics and synbiotics in the treatment of constipation and hemorrhoids

    Pandey, Ananya / Mazumder, Avijit / Das, Saumya / Das, Salauddin

    Allelopathy journal

    2023  Band 59, Heft 2, Seite(n) 187

    Dokumenttyp Artikel
    ZDB-ID 1232515-6
    ISSN 0971-4693
    Datenquelle Current Contents Medizin

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  7. Artikel: Comparing FRET pairs that report on intersubunit rotation in bacterial ribosomes.

    Das, Ananya / Bao, Chen / Ermolenko, Dmitri N

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Mediated by elongation factor G (EF-G), ribosome translocation along mRNA is accompanied by rotational movement between ribosomal subunits. Here, we reassess whether the intersubunit rotation requires GTP hydrolysis by EF-G or can occur spontaneously. To ...

    Abstract Mediated by elongation factor G (EF-G), ribosome translocation along mRNA is accompanied by rotational movement between ribosomal subunits. Here, we reassess whether the intersubunit rotation requires GTP hydrolysis by EF-G or can occur spontaneously. To that end, we employ two independent FRET assays, which are based on labeling either ribosomal proteins (bS6 and bL9) or rRNAs (h44 of 16S and H101 of 23S rRNA). Both FRET pairs reveal three FRET states, corresponding to the non-rotated, rotated and semi-rotated conformations of the ribosome. Both FRET assays show that in the absence of EF-G, pre-translocation ribosomes containing deacylated P-site tRNA undergo spontaneous intersubunit rotations between non-rotated and rotated conformations. While the two FRET pairs exhibit largely similar behavior, they substantially differ in the fraction of ribosomes showing spontaneous fluctuations. Nevertheless, instead of being an invariable intrinsic property of each FRET pair, the fraction of spontaneously fluctuating molecules changes in both FRET assays depending on experimental conditions. Our results underscore importance of using multiple FRET pairs in studies of ribosome dynamics and highlight the role of thermally-driven large-scale ribosome rearrangements in translation.
    Sprache Englisch
    Erscheinungsdatum 2023-05-09
    Erscheinungsland United States
    Dokumenttyp Preprint
    DOI 10.1101/2023.05.09.540051
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  8. Artikel: Impact of the COVID-19 pandemic on the workflow of an ambulatory endoscopy center: an assessment by discrete event simulation

    Das, Ananya

    Gastrointest Endosc

    Abstract: BACKGROUND AND AIMS: As community-based ambulatory endoscopy centers (AECs) across the nation are trying to reopen and safely resume outpatient endoscopic procedures after the unprecedented lockdown related to the coronavirus disease 2019 (COVID-19) ... ...

    Abstract BACKGROUND AND AIMS: As community-based ambulatory endoscopy centers (AECs) across the nation are trying to reopen and safely resume outpatient endoscopic procedures after the unprecedented lockdown related to the coronavirus disease 2019 (COVID-19) pandemic, guidelines recommend pretesting and screening for COVID-19 along with other mitigation measures for the safety of patients and staff. The impact of such changes in the workflow of AECs on throughput and other performance indicators is largely unknown, although a significant reduction in revenue stream is expected. METHODS: A discrete event simulation-based model was developed in the setting of a small to medium community-based single-specialty AEC to quantify the impact of COVID-19-related workflow changes on performance indicators and cost per case compared with the pre-COVID-19 baseline. RESULTS: In the simulation model, post-COVID-19 recommended workflow changes significantly impacted the operational and productivity metrics and, in turn, adversely affected financial metrics. Overall, there was a significant decrease in staff utilization and consequent increase in total facility time, waiting time for patients, and cost per case because of a bottleneck at the time of preprocedure COVID-19 screening and testing while practicing social distancing. Strategies to minimize this adverse impact on productivity were assessed. CONCLUSIONS: Pretesting and screening for COVID-19 as recommended by current guidelines will significantly impact the productivity and revenue stream of AECs. Urgent measures by payors are needed to adjust the facility reimbursement of endoscopy centers to ensure successful reopening and ramping up outpatient endoscopy services in these facilities already hit hard by the pandemic.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #595521
    Datenquelle COVID19

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  9. Artikel ; Online: Comparing the bone regeneration potential between a trabecular bone and a porous scaffold through osteoblast migration and differentiation: A multiscale approach.

    Majumder, Santanu / Gupta, Abhisek / Das, Ankita / Barui, Ananya / Das, Mitun / Chowdhury, Amit Roy

    International journal for numerical methods in biomedical engineering

    2024  , Seite(n) e3821

    Abstract: Both cell migration and osteogenic differentiation are critical for successful bone regeneration. Therefore, understanding the mechanobiological aspects that govern these two processes is essential in designing effective scaffolds that promote faster ... ...

    Abstract Both cell migration and osteogenic differentiation are critical for successful bone regeneration. Therefore, understanding the mechanobiological aspects that govern these two processes is essential in designing effective scaffolds that promote faster bone regeneration. Studying these two factors at different locations is necessary to manage bone regeneration in various sections of a scaffold. Hence, a multiscale computational model was used to observe the mechanical responses of osteoblasts placed in different positions of the trabecular bone and gyroid scaffold. Fluid shear stresses in scaffolds at cell seeded locations (representing osteogenic differentiation) and strain energy densities in cells at cell substrate interface (representing cell migration) were observed as mechanical response parameters in this study. Comparison of these responses, as two critical factors for bone regeneration, between the trabecular bone and gyroid scaffold at different locations, is the overall goal of the study. This study reveals that the gyroid scaffold exhibits higher osteogenic differentiation and cell migration potential compared to the trabecular bone. However, the responses in the gyroid only mimic the trabecular bone in two out of nine positions. These findings can guide us in predicting the ideal cell seeded sites within a scaffold for better bone regeneration and in replicating a replaced bone condition by altering the physical parameters of a scaffold.
    Sprache Englisch
    Erscheinungsdatum 2024-04-18
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2540968-2
    ISSN 2040-7947 ; 2040-7939
    ISSN (online) 2040-7947
    ISSN 2040-7939
    DOI 10.1002/cnm.3821
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  10. Artikel ; Online: Determining the Efficacy of Pembrolizumab in Patients With Previously Treated Advanced Hepatocellular Carcinoma.

    Lin, Timothy A / Das, Ananya / McCaw, Zachary / Ludmir, Ethan B

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2023  Band 41, Heft 16, Seite(n) 3074–3075

    Mesh-Begriff(e) Humans ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/drug therapy ; Liver Neoplasms/pathology ; Antibodies, Monoclonal, Humanized/therapeutic use ; Lung Neoplasms/drug therapy
    Chemische Substanzen pembrolizumab (DPT0O3T46P) ; Antibodies, Monoclonal, Humanized
    Sprache Englisch
    Erscheinungsdatum 2023-04-04
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.23.00072
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