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Article ; Online: Cross-state Border Nicotine Vaping Products Purchase - Early Evidence from State Emergency Sales Restrictions in 2019.

Cheng, Kai-Wen / Liber, Alex C / Levy, David T

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco

2024

Abstract: Introduction: While retail sales and retailer inspection studies generally indicate high compliance with state sales restrictions on Nicotine Vaping Products (NVPs) within the restricted area, studies using survey data generally indicate that most users ...

Abstract	Introduction: While retail sales and retailer inspection studies generally indicate high compliance with state sales restrictions on Nicotine Vaping Products (NVPs) within the restricted area, studies using survey data generally indicate that most users could readily continue gaining access to restricted NVPs. Our study bridges a gap in the current literature and investigates the potential role of cross-state border purchases to evade state emergency NVP sales restrictions in 2019. Methods: The study sample was restricted to NVP sales from the states neighboring Massachusetts (MA), Rhode Island (RI), and Washington (WA), three states that implemented all NVP or flavored NVP sales restrictions in 2019. Among these neighboring states, the 2019 weekly county-level NVP sales by flavors (tobacco, mint/menthol, and other flavors) were compiled using Nielsen Scanner data. A quasi-experimental, comparison group pre-post study design was used to study the impacts of NVP sales restrictions on cross-state border NVP purchases. Results: Weekly NVP sales for border counties significantly increased in response to the MA, RI, and WA bans for tobacco flavored (56%, 45%, 14%, respectively), menthol/mint flavored (51%, 2%, 41%, respectively), and other flavored (79%, 3%, 4%, respectively) products, compared to sales for non-border counties (all p-values <0.01). Conclusions: Our study identified significant cross-state border NVP purchases in all studied states to circumvent NVP emergency sales restrictions in response to the EVALI outbreak. Policymakers should factor in these purchasing behaviors to evade sales restrictions when evaluating any future potential policies at the state or local levels. Implications: While retail sales data and retailer inspections indicate high compliance with Nicotine Vaping Product (NVP) flavor sales restrictions from major retail outlets, survey data obtain mixed findings on the effects of sales restrictions on vaping behaviors. Our study identified a significant increase in cross-state border NVP purchases to circumvent NVP sales restrictions in 2019, consistent across all three settings of Massachusetts, Rhode Island, and Washington. Policymakers should factor in these cross-state border NVP purchases in response to sales restrictions when evaluating any future potential NVP sales restrictions.
Language	English
Publishing date	2024-01-31
Publishing country	England
Document type	Journal Article
ZDB-ID	1452315-2
ISSN	1469-994X ; 1462-2203
ISSN (online)	1469-994X
ISSN	1462-2203
DOI	10.1093/ntr/ntae017
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Zs.A 5789: Show issues

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Article ; Online: Application of Bidirectional Long Short-Term Memory to Adaptive Streaming for Internet of Autonomous Vehicles.

Huang, Chenn-Jung / Hu, Kai-Wen / Cheng, Hao-Wen

Biomimetics (Basel, Switzerland)

2023 Volume 8, Issue 6

Abstract: It is expected that interconnected networks of autonomous vehicles, especially during peak traffic, will face congestion challenges. Moreover, the existing literature lacks discussions on integrating next-generation wireless communication technologies ... ...

Abstract	It is expected that interconnected networks of autonomous vehicles, especially during peak traffic, will face congestion challenges. Moreover, the existing literature lacks discussions on integrating next-generation wireless communication technologies into connected vehicular networks. Hence, this paper introduces a tailored bandwidth management algorithm for streaming applications of autonomous vehicle passengers. It leverages cutting-edge 6G wireless technology to create a network with high-speed transmission and broad coverage, ensuring smooth streaming application performance. The key features of bandwidth allocation for diverse streaming applications in this work include bandwidth relay and pre-loading of video clips assisted by vehicle-to-vehicle communication. Through simulations, this research effectively showcases the algorithm's ability to fulfill the bandwidth needs of diverse streaming applications for autonomous vehicle passengers. Specifically, during periods of peak user bandwidth demand, it notably increases the bandwidth accessible for streaming applications. On average, users experience a substantial 55% improvement in the bandwidth they can access. This validation affirms the viability and promise of the proposed approach in efficiently managing the intricate complexities of bandwidth allocation issues for streaming services within the connected autonomous vehicular networks.
Language	English
Publishing date	2023-10-01
Publishing country	Switzerland
Document type	Journal Article
ISSN	2313-7673
ISSN (online)	2313-7673
DOI	10.3390/biomimetics8060467
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Article ; Online: An Adaptive Bandwidth Management Algorithm for Next-Generation Vehicular Networks.

Huang, Chenn-Jung / Hu, Kai-Wen / Cheng, Hao-Wen

Sensors (Basel, Switzerland)

2023 Volume 23, Issue 18

Abstract: The popularity of video services such as video call or video on-demand has made it impossible for people to live without them in their daily lives. It can be anticipated that the explosive growth of vehicular communication owing to the widespread use of ... ...

Abstract	The popularity of video services such as video call or video on-demand has made it impossible for people to live without them in their daily lives. It can be anticipated that the explosive growth of vehicular communication owing to the widespread use of in-vehicle video infotainment applications in the future will result in increasing fragmentation and congestion of the wireless transmission spectrum. Accordingly, effective bandwidth management algorithms are demanded to achieve efficient communication and stable scalability in next-generation vehicular networks. To the best of our current knowledge, a noticeable gap remains in the existing literature regarding the application of the latest advancements in network communication technologies. Specifically, this gap is evident in the lack of exploration regarding how cutting-edge technologies can be effectively employed to optimize bandwidth allocation, especially in the realm of video service applications within the forthcoming vehicular networks. In light of this void, this paper presents a seamless integration of cutting-edge 6G communication technologies, such as terahertz (THz) and visible light communication (VLC), with the existing 5G millimeter-wave and sub-6 GHz base stations. This integration facilitates the creation of a network environment characterized by high transmission rates and extensive coverage. Our primary aim is to ensure the uninterrupted playback of real-time video applications for vehicle users. These video applications encompass video conferencing, live video, and on-demand video services. The outcomes of our simulations convincingly indicate that the proposed strategy adeptly addresses the challenge of bandwidth competition among vehicle users. Moreover, it notably boosts the efficient utilization of bandwidth from less crowded base stations, optimizes the fulfillment of bandwidth prerequisites for various video applications, and elevates the overall video quality experienced by users. Consequently, our findings serve as a successful validation of the practicality and effectiveness of the proposed methodology.
Language	English
Publishing date	2023-09-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s23187767
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Lactic acidosis in a patient who ingested rotenone-containing beans (

Cheng, Kai-Wen / Chen, Hsien-Yi / Huang, Chun-Fa / Wang, Te-Hao / Yu, Jiun-Hao

Clinical toxicology (Philadelphia, Pa.)

2023 Volume 61, Issue 4, Page(s) 316–317

MeSH term(s)	Humans ; Pachyrhizus ; Rotenone ; Acidosis, Lactic
Chemical Substances	Rotenone (03L9OT429T)
Language	English
Publishing date	2023-03-29
Publishing country	England
Document type	Letter
ZDB-ID	204476-6
ISSN	1556-9519 ; 0009-9309 ; 0731-3810 ; 1556-3650
ISSN (online)	1556-9519
ISSN	0009-9309 ; 0731-3810 ; 1556-3650
DOI	10.1080/15563650.2023.2185495
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Zs.B 419: Show issues

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Article: LINKIN-associated proteins necessary for tissue integrity during collective cell migration.

Tan, Chieh-Hsiang / Cheng, Kai-Wen / Park, Heenam / Chou, Tsui-Fen / Sternberg, Paul W

bioRxiv : the preprint server for biology

2023

Abstract: Cell adhesion plays essential roles in almost every aspect of metazoan biology. LINKIN (Human: ITFG1, ...

Abstract	Cell adhesion plays essential roles in almost every aspect of metazoan biology. LINKIN (Human: ITFG1,
Language	English
Publishing date	2023-08-04
Publishing country	United States
Document type	Preprint
DOI	10.1101/2023.02.08.527750
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Article ; Online: A Mission-Oriented Flight Path and Charging Mechanism for Internet of Drones.

Huang, Chenn-Jung / Hu, Kai-Wen / Cheng, Hao-Wen / Sie Lin, Yi-Sin

Sensors (Basel, Switzerland)

2023 Volume 23, Issue 9

Abstract: In addition to traditional battery exchange services and stationary charging stations, researchers have proposed wireless charging technology, such as decentralized laser charging or drone-to-drone charging in flight, to provide power to drones with ... ...

Abstract	In addition to traditional battery exchange services and stationary charging stations, researchers have proposed wireless charging technology, such as decentralized laser charging or drone-to-drone charging in flight, to provide power to drones with insufficient battery electricity. However, the charging methods presented in the literature will inevitably cause drones to wait in line for charging during peak hours and disrupt their scheduled trips when the number of drones grows rapidly in the future. To the best of our knowledge, there have been no integrated solutions for drone flight path and charging planning to alleviate charging congestion, taking into account the different mission characteristics of drones and the charging cost considerations of drone operators. Accordingly, this paper provides adaptive charging options to help drone operators to solve the above-mentioned problems. Drones on ordinary missions can use conventional battery swap services, wired charging stations, or electromagnetic wireless charging stations to recharge their batteries as usual, whereas drones on time-critical missions can choose drone-to-drone wireless charging or decentralized laser charging deployed along the fight paths to charge the batteries of drones in flight. Notably, since fixed-wing drones have larger wing areas to install solar panels, they can also use solar energy to charge during flight if the weather is clear. The simulation results exhibited that the proposed work reduced the power load of the power grid during peak hours, met the charging needs of each individual drone during flight, and cut down the charging costs of drone operators. As a result, an all-win situation for drone operators, drone customers, and power grid operators was achieved.
Language	English
Publishing date	2023-04-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s23094269
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Article ; Online: The Experiences of Female Partners of Patients With Erectile Dysfunction Due to Prostate Cancer Treatment in China: A Qualitative Exploration.

Wang, Tong / Cheng, Hui-Lin / Li, Kai-Wen / Wong, Ping Kit Kitty / Dong, Wen

Cancer nursing

2023

Abstract: Background: Because of sociocultural factors, Chinese female partners of patients with prostate cancer (PC) may have perspectives and needs that differ from the more published reports of female partners living in Western cultures.: Objectives: The ... ...

Abstract	Background: Because of sociocultural factors, Chinese female partners of patients with prostate cancer (PC) may have perspectives and needs that differ from the more published reports of female partners living in Western cultures. Objectives: The aim of this study was to explore the experiences of female partners of patients with PC experiencing erectile dysfunction in China. Interventions/methods: In this interpretive descriptive design, qualitative data were collected from semistructured telephone interviews with purposively sampled participants from the urology outpatient unit in a hospital in South China. The interviews were audiotaped, transcribed, and analyzed using a constant comparison approach. Results: Three themes emerged from the analysis of the participants' narratives: (a) acceptance of ceasing sex; (b) preserving intimacy through caregiving; and (c) the need for sexual health-related information. Conclusion: Participants in this study reported that their own sexuality and intimacy were affected by their partner's erectile dysfunction, but they adjusted to sexuality and intimacy changes through their caregiving of their husbands owing to Chinese traditional perspectives on women's obligations. They also reported having unmet informational needs in improving sexual well-being for the sake of their partners, lending further support to the likely benefit of couple-based educational interventions addressing sexual wellness in dyads affected by PC and erectile dysfunction. Implications for practice: The present study findings highlighted the need for more research attention to the support of Chinese female partners of patients with PC regarding sexual and intimate topics.
Language	English
Publishing date	2023-10-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	391995-x
ISSN	1538-9804 ; 0162-220X
ISSN (online)	1538-9804
ISSN	0162-220X
DOI	10.1097/NCC.0000000000001282
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Zs.A 1538: Show issues

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Article ; Online: Rapid Screening of New Psychoactive Substances Using pDART-QqQ-MS.

Hsu, Wei-Hsin / Cheng, Kai-Wen / Feng, Tzu-Hsuan / Chen, Ju-Yu / Chen, Guan-Yuan / Chen, Lian-Yu / Weng, Te I / Hsu, Cheng-Chih

Journal of the American Society for Mass Spectrometry

2024

Abstract: Drug abuse is a severe social problem worldwide. Particularly, the issue of new psychoactive substances (NPSs) have increasingly emerged. NPSs are structural or functional analogs of traditional illicit drugs, such as cocaine, cannabis, and amphetamine; ... ...

Abstract	Drug abuse is a severe social problem worldwide. Particularly, the issue of new psychoactive substances (NPSs) have increasingly emerged. NPSs are structural or functional analogs of traditional illicit drugs, such as cocaine, cannabis, and amphetamine; these molecules provide the same or more severe neurological effects. Usually, immunoassays are utilized in the preliminary screening method. However, NPSs have poor detectability in commercially available immunoassay kits. Meanwhile, various chromatography combined with the mass spectrometry platform have been developed to quantify NPSs. Still, a significant amount of time and resources are required during these procedures. Therefore, we established a rapid analytical platform for NPSs employing paper-loaded direct analysis in real time triple quadrupole mass spectrometry (pDART-QqQ-MS). We implemented this platform for the semiquantitative analysis of forensic drug tests in urine. This platform significantly shrinks the analytical time of a single sample within 30 s and requires a low volume of the specimen. The platform can detect 21 NPSs in urine mixtures at a lower limit of qualification of concentration ranging from 20 to 75 nanograms per milliliter (ng mL
Language	English
Publishing date	2024-04-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	1073671-2
ISSN	1879-1123 ; 1044-0305
ISSN (online)	1879-1123
ISSN	1044-0305
DOI	10.1021/jasms.4c00124
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Zs.A 4618: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 241: Show issues

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Article ; Online: Investigating the Metabolic Heterogeneity of Cancer Cells Using Functional Single-Cell Selection and nLC Combined with Multinozzle Emitter Mass Spectrometry.

Cheng, Kai-Wen / Su, Pin-Rui / Feller, Kate Jo-Ann / Chien, Miao-Ping / Hsu, Cheng-Chih

Analytical chemistry

2023 Volume 96, Issue 2, Page(s) 624–629

Abstract: Tumor metastasis and cancer recurrence are often a result of cell heterogeneity, where specific subpopulations of tumor cells may be resistant to radio- or chemotherapy. To investigate this physiological and phenotypic diversity, single-cell metabolomics ...

Abstract	Tumor metastasis and cancer recurrence are often a result of cell heterogeneity, where specific subpopulations of tumor cells may be resistant to radio- or chemotherapy. To investigate this physiological and phenotypic diversity, single-cell metabolomics provides a powerful approach at the chemical level, where distinct lipid profiles can be found in different tumor cells. Here, we established a highly sensitive platform using nanoflow liquid chromatography (nLC) combined with multinozzle emitter electrospray ionization mass spectrometry for more in-depth metabolomics profiling. Our platform identified 15 and 17 lipids from individual osteosarcoma (U2OS) and glioblastoma (GBM) cells when analyzing single-cell samples. Additionally, we used the functional single-cell selection (fSCS) pipeline to analyze the subpopulations of cells with a DNA damage response (DDR) in U2OS cells and fast migration in GBM cells. Specifically, we observed a down-regulation of polyunsaturated fatty acids (PUFAs) in U2OS cells undergoing DDR, such as fatty acids FA 20:3; O2 and FA 17:4; O3. Furthermore, ceramides (Cer 38:0; O3) and triglycerides (TG 36:0) were found to be down-regulated in fast-migrating GBM cells compared to the slow-migrating subpopulation. These findings suggest the potential roles of these metabolites and/or lipids in the cellular behavior of the subpopulations.
MeSH term(s)	Humans ; Chromatography, Liquid/methods ; Spectrometry, Mass, Electrospray Ionization/methods ; Metabolomics/methods ; Fatty Acids, Unsaturated/metabolism ; Triglycerides ; Glioblastoma
Chemical Substances	Fatty Acids, Unsaturated ; Triglycerides
Language	English
Publishing date	2023-12-29
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1508-8
ISSN	1520-6882 ; 0003-2700
ISSN (online)	1520-6882
ISSN	0003-2700
DOI	10.1021/acs.analchem.3c03688
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Zs.A 4033: Show issues

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Article ; Online: National emergency medical teleconsultation: A novel system applied during the COVID-19 pandemic in Taiwan.

Cheng, Kai-Wen / Shih, Hong-Mo / Ng, Chip-Jin / Shih, Chung-Liang / Chen, Wei-Kung

Journal of telemedicine and telecare

2023 , Page(s) 1357633X231217326

Abstract: Objective: Telemedicine can facilitate social distancing during an infectious disease pandemic and reduce the burden on health-care resources. Moreover, telemedicine can be utilized for medical care in remote island regions, in home health care, and ... ...

Abstract	Objective: Telemedicine can facilitate social distancing during an infectious disease pandemic and reduce the burden on health-care resources. Moreover, telemedicine can be utilized for medical care in remote island regions, in home health care, and during isolated major disasters such as regional earthquakes. However, the effectiveness of telemedicine for emergency consultation remains unclear. This study introduced and analyzed the national emergency medical teleconsultation (NEMTC) established in Taiwan in 2022 during the COVID-19 pandemic. Methods: In response to the COVID-19 pandemic, Taiwan's Centers for Disease Control established a temporary 24-h NEMTC contingency system. Patient information was collected from consultations through the NEMTC from April 28 to June 28, 2022. After successful consultation, physicians made recommendations for home observation, emergency department (ED) visit, or outpatient follow-up. ED visits were divided into two categories, namely self-transport and transport, by the emergency medical service system (EMSS). Results: During the aforementioned period, 20,902 consultation requests were made through the NEMTC, and 11,804 consultations (56.5% of 20,902) were successful. Consultation success rates were significantly higher for those who had a consultation between 08:00 and 16:00, had a waiting time of less than 10 min, and were not aged between 18 and 45 years. Moreover, 8.2% of the analyzed patients were advised to visit the ED, and only 0.4% required ambulance transportation. Children and older individuals and patients with cardiovascular symptoms, shortness of breath, or neurological or abdominal symptoms had a significantly higher chance of being referred to the ED than did other individuals. Conclusions: The NEMTC response system can enhance the efficiency of the EMSS and can reduce the burden of patients with mild conditions overloading the EMSS and EDs. The NEMTC could serve as an effective rapid response system during future pandemics.
Language	English
Publishing date	2023-12-21
Publishing country	England
Document type	Journal Article
ZDB-ID	1340281-x
ISSN	1758-1109 ; 1357-633X
ISSN (online)	1758-1109
ISSN	1357-633X
DOI	10.1177/1357633X231217326
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