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Article ; Online: Assessing radical scavenging activity, potential antidiabetic, antigout and in vitro anti-inflammatory properties of Syzygium nervosum A.Cunn. ex DC. grown in Vietnam

Trang H.D. Nguyen

Journal of Agriculture and Food Research, Vol 12, Iss , Pp 100614- (2023)

2023

Abstract: Syzygium nervosum A.Cunn. ex DC., commonly grown in Southern China, Southeast Asia and part of Australia, is among the well-known herbal teas in Vietnam and China. The study aimed to determine phenolics, antioxidant, potential anti-inflammatory, antigout ...

Abstract	Syzygium nervosum A.Cunn. ex DC., commonly grown in Southern China, Southeast Asia and part of Australia, is among the well-known herbal teas in Vietnam and China. The study aimed to determine phenolics, antioxidant, potential anti-inflammatory, antigout and antidiabetic properties of various extracts of the plant leaves obtained from methanol, ethanol and ethyl acetate. The use of the solvents had considerable impacts upon the phenolic composition and bioactivities of the extracts. The methanolic extract contained significantly higher levels of most of the phenolics in comparison to the ethanolic and ethyl acetate extracts. It also exhibited the most potent DPPH radical scavenging activity (IC50 = 11.76 μg/mL), comparable to that of ascorbic acid. The results demonstrated that the methanolic extract may possess the strongest inhibitory effects on α-glucosidase and bovine albumin denaturation with IC50 values averaging 27.66 and 156.55 μg/mL, respectively. Regarding antigout potential, the ethanolic and ethyl acetate extracts presented higher activity to inhibit xanthine oxidase. The research provides a better understanding of phenolic constituents and potential health-endorsing properties of S. nervosum, which is important for developing plant-derived agents for disease prevention and treatment.
Keywords	Syzygium nervosum ; Phenolics ; Antioxidant ; Antidiabetic ; Anti-inflammatory ; Agriculture (General) ; S1-972 ; Nutrition. Foods and food supply ; TX341-641
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Facile synthesis of gold nanostars for the duplex detection of pesticide residues in grapes using SERS.

Zhai, Kairui / Sun, Lin / Nguyen, Trang H D / Lin, Mengshi

Journal of food science

2024 Volume 89, Issue 4, Page(s) 2512–2521

Abstract: In recent years, concerns have been raised regarding the contamination of grapes with pesticide residues. As consumer demand for safer food products grows, regular monitoring of pesticide residues in food has become essential. This study sought to ... ...

Abstract	In recent years, concerns have been raised regarding the contamination of grapes with pesticide residues. As consumer demand for safer food products grows, regular monitoring of pesticide residues in food has become essential. This study sought to develop a rapid and sensitive technique for detecting two specific pesticides (phosmet and paraquat) present on the grape surface using the surface-enhanced Raman spectroscopy (SERS) method. Gold nanostars (AuNS) particles were synthesized, featuring spiky tips that act as hot spots for localized surface plasmon resonance, thereby enhancing Raman signals. Additionally, the roughened surface of AuNS increases the surface area, resulting in improved interactions between the substrate and analyte molecules. Prominent Raman peaks of mixed contaminants were acquired and used to characterize and quantify the pesticides. It was observed that the SERS intensity of the Raman peaks changed in proportion to the concentration ratio of phosmet and paraquat. Moreover, AuNS exhibited superior SERS enhancement compared to gold nanoparticles. The results demonstrate that the lowest detectable concentration for both pesticides on grape surfaces is 0.5 mg/kg. These findings suggest that SERS coupled with AuNS constitutes a practical and promising approach for detecting and quantifying trace contaminants in food. PRACTICAL APPLICATION: This research established a novel surface-enhanced Raman spectroscopy (SERS) method coupled with a simplified extraction protocol and gold nanostar substrates to detect trace levels of pesticides in fresh produce. The detection limits meet the maximum residue limits set by the EPA. This substrate has great potential for rapid measurements of chemical contaminants in foods.
MeSH term(s)	Pesticide Residues/analysis ; Vitis ; Gold/chemistry ; Phosmet ; Paraquat ; Metal Nanoparticles/chemistry ; Pesticides/analysis ; Spectrum Analysis, Raman/methods
Chemical Substances	Pesticide Residues ; Gold (7440-57-5) ; Phosmet (VN04LI540Y) ; Paraquat (PLG39H7695) ; Pesticides
Language	English
Publishing date	2024-02-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	241615-3
ISSN	1750-3841 ; 0022-1147
ISSN (online)	1750-3841
ISSN	0022-1147
DOI	10.1111/1750-3841.16986
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: May New Locally Acquired Cases of COVID-19 Have Been Linked to Illegal Entry into Vietnam?

Nguyen, Trang H D

Disaster medicine and public health preparedness

2020 Volume 15, Issue 4, Page(s) e36–e37

MeSH term(s)	COVID-19/epidemiology ; COVID-19/transmission ; Community-Acquired Infections/epidemiology ; Contact Tracing ; Emigration and Immigration/legislation & jurisprudence ; Humans ; Vietnam/epidemiology
Keywords	covid19
Language	English
Publishing date	2020-10-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	2375268-3
ISSN	1938-744X ; 1935-7893
ISSN (online)	1938-744X
ISSN	1935-7893
DOI	10.1017/dmp.2020.414
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Lifting of Social Distancing Measures: Perspectives From Vietnam.

Nguyen, Trang H D

Disaster medicine and public health preparedness

2020 Volume 15, Issue 2, Page(s) e40–e42

Abstract: ... COVID-19), Vietnam has seen no new locally acquired cases since April 16. After implementing 22 d ...

Abstract	While many nations are struggling to slow the transmission rate of the coronavirus disease 2019 (COVID-19), Vietnam has seen no new locally acquired cases since April 16. After implementing 22 d of nationwide social distancing, on April 23, the government of Vietnam announced the easing of social distancing measures. This allows the country to restart its socio-economic activities in a gradual, prudent manner. Domestic tourism and exports of agricultural and anti-COVID-19 medical products take priority over the other sectors in this postpandemic economic recovery. Importantly, the country needs to stay vigilant on the fight against the disease to prevent a possibility of another outbreak.
Keywords	covid19
Language	English
Publishing date	2020-07-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2375268-3
ISSN	1938-744X ; 1935-7893
ISSN (online)	1938-744X
ISSN	1935-7893
DOI	10.1017/dmp.2020.238
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Influence of sprouting on phenolic acids, carotenoids, and antioxidant activity of millet varieties

Trang H.D. Nguyen / Lien L.P. Nguyen / Laszlo Baranyai

Journal of Agriculture and Food Research, Vol 14, Iss , Pp 100810- (2023)

2023

Abstract: The kernels of two millet varieties (foxtail and red proso) were germinated for 24, 48, and 72 h ... scavenged ABTS free radicals, increasing from 351.47 (0 h) to 521.58 μg AAE/g (72 h) in foxtail and from 288 ... 12 (0 h) to 692.46 μg AAE/g (72 h) in red proso. A similar trend was observed in the millets ...

Abstract	The kernels of two millet varieties (foxtail and red proso) were germinated for 24, 48, and 72 h at 30 °C. Changes in free and bound forms of phenolic acids, lutein/zeaxanthin, and antioxidant activity were evaluated in wholegrain flours from the germinated seeds. Lutein/zeaxanthin increased from 4.08 to 6.65 μg/g in foxtail and from 1.62 to 4.85 μg/g in red proso millets. The two millets significantly scavenged ABTS free radicals, increasing from 351.47 (0 h) to 521.58 μg AAE/g (72 h) in foxtail and from 288.12 (0 h) to 692.46 μg AAE/g (72 h) in red proso. A similar trend was observed in the millets regarding the DPPH assay, in which DPPH free radicals were scavenged from 140.69 (0 h) to 314.25 μg AAE/g (72 h) and from 290.59 to 432.05 μg AAE/g, respectively. Free ferulic acid content was higher in germinated flour for 24 h (1.57 mg/kg dry weight basis) than in ungerminated grains (0.05 mg/kg). The concentrations of bound caffeic acid increased with germination time, from 12.78 mg/kg (0 h) to 31.2 mg/kg in germinated flour for 24 h. The foxtail millet had significant changes in phenolic acid content during germination. This study may provide insights into utilizing different millet varieties and their sprouted flours in food industry.
Keywords	Germination ; Phenolic acids ; Millet ; Foxtail ; Red proso ; Agriculture (General) ; S1-972 ; Nutrition. Foods and food supply ; TX341-641
Subject code	630
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A Review on Phytochemical Composition and Potential Health-promoting Properties of Walnuts

Nguyen, Trang H.D. / Vu, Danh C.

Food Reviews International. 2023 Jan. 02, v. 39, no. 1 p.397-423

2023

Abstract: Walnuts are among the commonly consumed oil nuts in the world. The nuts typically contain 40–70% oil, and are a rich source of fatty acids, phenolics, phytosterols, tocopherols and carotenoids. The levels of unsaturated fatty acids and tocopherols in ... ...

Abstract	Walnuts are among the commonly consumed oil nuts in the world. The nuts typically contain 40–70% oil, and are a rich source of fatty acids, phenolics, phytosterols, tocopherols and carotenoids. The levels of unsaturated fatty acids and tocopherols in walnuts were significantly higher than those of many other widely consumed oil nuts. The presence of phytochemicals in walnuts gives rise to multiple bioactivities, such as antioxidant, anti-inflammatory properties, and cholesterol lowering activity. The addition of walnut to a diet could enable delay of the onset of neurodegenerative disorders, protection against the development of certain cancers. Agronomic practices, environmental and climatic conditions, geographic locations, harvesting and postharvest handling practices have impacts upon phytochemical levels in walnuts. Abbreviations: LDL: low-density lipoprotein; HDL: high-density lipoprotein; GC-FID: gas chromatography-flame ionization detector; GC-MS: gas chromatography-mass spectrometry; HPLC-DAD: high-performance liquid chromatography-diode array detector; LC-MS/MS: liquid chromatography-tandem mass spectrometry; CE-MS: capillary electrophoresis–mass spectrometry; NMR: nuclear magnetic resonance; Aβ: amyloid beta protein; ROS: reactive oxygen species; DCF: dichlorofluorescein; DCFH-DA: dichlorofluorescin diacetate; SOD: superoxide dismutase; CAT: catalase; GR: glutathione reductase; GPx: glutathione peroxidase; GST: glutathione S-transferase; GSH: glutathione; LDH: lactate dehydrogenase; VCAM-1: vascular cell adhesion molecule: ICAM-1: intracellular adhesion molecule; TNF-α: tumor necrosis factor α; IL-6: interleukin 6; NF-κB: nuclear factor kappa light chain enhancer of activated B cells; IL-1β: interleukin 1β; IL-8: interleukin 8; IL-10: interleukin 10; MCP-1: monocyte chemoattractant protein 1; mTOR: mammalian target of rapamycin; ATG7: autophagy related 7; MAP1BLC3: microtubule-associated proteins 1A/1B light chain 3; PMA: phorbol 12-myristate 13-acetate; LPS: lipopolysaccharide; iNOS: inducible nitric oxide synthase; COX-2: cyclooxygenase 2; IGF-1: plasma insulin-like growth factor 1; GSTT2: glutathione S-transferase theta 2; GSK3β: glycogen synthase kinase 3 beta; ALA: α-linolenic acid; CD133: CD133 antigen; CD44: CD44 antigen; DLK1: Protein delta homolog 1; EPA: eicosapentaenoic acid; DHA: docosahexaenoic acid; Bcl-2: B-cell lymphoma 2; IL-1α: interleukin 1α; MAO-B: monoamine oxidase B; MPTP: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP⁺: 1-methyl-4-phenylpyridinium; BLM: bleomycin; CSE: cigarette smoke emission.
Keywords	B-cell lymphoma ; adhesion ; amine oxidase (flavin-containing) ; amyloid ; antigens ; autophagy ; capillary electrophoresis ; carotenoids ; catalase ; chemical constituents of plants ; chemokine CCL2 ; cholesterol ; cigarettes ; diet ; docosahexaenoic acid ; eicosapentaenoic acid ; flame ionization ; gas chromatography-mass spectrometry ; glutathione ; glutathione peroxidase ; glutathione transferase ; glutathione-disulfide reductase ; health promotion ; high density lipoprotein ; inducible nitric oxide synthase ; insulin-like growth factor I ; intercellular adhesion molecule-1 ; interleukin-10 ; interleukin-6 ; interleukin-8 ; lactate dehydrogenase ; lipopolysaccharides ; liquid chromatography ; low density lipoprotein ; mammals ; nuclear magnetic resonance spectroscopy ; oils ; phenolic compounds ; phytosterols ; prostaglandin synthase ; rapamycin ; reactive oxygen species ; smoke ; superoxide dismutase ; tandem mass spectrometry ; tau-protein kinase ; tocopherols ; tumor necrosis factors ; vascular cell adhesion molecules ; walnuts ; Walnut ; juglans ; phytochemicals ; phenolics ; antioxidant
Language	English
Dates of publication	2023-0102
Size	p. 397-423.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	53834-6
ISSN	1525-6103 ; 8755-9129
ISSN (online)	1525-6103
ISSN	8755-9129
DOI	10.1080/87559129.2021.1912084
Database	NAL-Catalogue (AGRICOLA)

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Z 5497: Show issues

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Article: May the new locally-acquired cases of COVID-19 have been linked to illegal entry into Vietnam?

Nguyen, Trang H D

Disaster Med Public Health Prep

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #889073
Database	COVID19

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Article ; Online: May the Vietnam Response Have Reduced Daily New Cases of COVID-19 in the Country?

Vu, Danh C / Nguyen, Trang H D / Ho, Thi L

Disaster medicine and public health preparedness

2022 Volume 17, Page(s) e124

Abstract: Vietnam, a Southeast Asian country, has documented 1,515 polymerase chain reaction-positive confirmed coronavirus disease 2019 (COVID-19) cases with 35 deaths a year after the first infection recorded in Ha Noi on January 23, 2020. Half of the infected ... ...

Abstract	Vietnam, a Southeast Asian country, has documented 1,515 polymerase chain reaction-positive confirmed coronavirus disease 2019 (COVID-19) cases with 35 deaths a year after the first infection recorded in Ha Noi on January 23, 2020. Half of the infected patients are at the age of 21 to 40 y. While numbers of infections in many countries in the region continue to surge, Vietnam is seeing decreases in the number of daily new cases. As a result of COVID-19 trajectory different from the other countries, as of April 23, 2020, Vietnam is no longer under lockdown and is slowly restarting its socioeconomic activities. This report aims to provide a summary of the COVID-19 situation and response to the pandemic in Vietnam.
MeSH term(s)	Humans ; Communicable Disease Control ; COVID-19/epidemiology ; COVID-19/prevention & control ; Vietnam/epidemiology ; Young Adult ; Adult
Language	English
Publishing date	2022-02-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2375268-3
ISSN	1938-744X ; 1935-7893
ISSN (online)	1938-744X
ISSN	1935-7893
DOI	10.1017/dmp.2022.33
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: May the new locally-acquired cases of COVID-19 have been linked to illegal entry into Vietnam?

Nguyen, Trang H.D.

Disaster Medicine and Public Health Preparedness

2020 , Page(s) 1–5

Keywords	Public Health, Environmental and Occupational Health ; covid19
Language	English
Publisher	Cambridge University Press (CUP)
Publishing country	uk
Document type	Article ; Online
ZDB-ID	2375268-3
ISSN	1938-744X ; 1935-7893
ISSN (online)	1938-744X
ISSN	1935-7893
DOI	10.1017/dmp.2020.414
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Estimation of place-based vulnerability scores for HIV viral non-suppression: an application leveraging data from a cohort of people with histories of using drugs.

Nguyen, Trang Quynh / Roberts Lavigne, Laken C / Brantner, Carly Lupton / Kirk, Gregory D / Mehta, Shruti H / Linton, Sabriya L

BMC medical research methodology

2024 Volume 24, Issue 1, Page(s) 21

Abstract: The relationships between place (e.g., neighborhood) and HIV are commonly investigated. As measurements of place are multivariate, most studies apply some dimension reduction, resulting in one variable (or a small number of variables), which is then used ...

Abstract	The relationships between place (e.g., neighborhood) and HIV are commonly investigated. As measurements of place are multivariate, most studies apply some dimension reduction, resulting in one variable (or a small number of variables), which is then used to characterize place. Typical dimension reduction methods seek to capture the most variance of the raw items, resulting in a type of summary variable we call "disadvantage score". We propose to add a different type of summary variable, the "vulnerability score," to the toolbox of the researchers doing place and HIV research. The vulnerability score measures how place, as known through the raw measurements, is predictive of an outcome. It captures variation in place characteristics that matters most for the particular outcome. We demonstrate the estimation and utility of place-based vulnerability scores for HIV viral non-suppression, using data with complicated clustering from a cohort of people with histories of injecting drugs.
MeSH term(s)	Humans ; HIV Infections/drug therapy ; Residence Characteristics
Language	English
Publishing date	2024-01-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2041362-2
ISSN	1471-2288 ; 1471-2288
ISSN (online)	1471-2288
ISSN	1471-2288
DOI	10.1186/s12874-023-02133-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

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