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  1. Article: [Risk Factors, Prevention, Diagnosis, and Treatment of Bronchopleural Fistula After Lung Resection].

    Suzuki, Makoto

    Kyobu geka. The Japanese journal of thoracic surgery

    2023  Volume 76, Issue 10, Page(s) 865–869

    Abstract: Postoperative bronchopleural fistula (BPF) is a rare but severe and sometimes life-threatening complication that needs immediate and proper treatment. Thoracic surgeons should strictly manage the comorbidities such as diabetes mellitus for BPF prevention. ...

    Abstract Postoperative bronchopleural fistula (BPF) is a rare but severe and sometimes life-threatening complication that needs immediate and proper treatment. Thoracic surgeons should strictly manage the comorbidities such as diabetes mellitus for BPF prevention. Also, coverage of the bronchial stump with pericardial fat tissue will prevent BPF, or at least prevent the turning severe of BPF. However, when BPF occurs, we must promptly determine whether to perform conservative treatment or invasive treatment such as fenestration.
    MeSH term(s) Humans ; Pneumonectomy/adverse effects ; Bronchial Fistula/etiology ; Bronchial Fistula/prevention & control ; Pleural Diseases/diagnosis ; Pleural Diseases/etiology ; Pleural Diseases/prevention & control ; Risk Factors ; Postoperative Complications/prevention & control ; Postoperative Complications/etiology ; Lung ; Lung Neoplasms/surgery
    Language Japanese
    Publishing date 2023-12-06
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 603899-2
    ISSN 0021-5252
    ISSN 0021-5252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Three main factors associated with fatal destiny of infective endocarditis.

    Suzuki, Makoto

    International journal of cardiology

    2021  Volume 333, Page(s) 184–185

    MeSH term(s) Endocarditis/diagnostic imaging ; Endocarditis, Bacterial/diagnostic imaging ; Follow-Up Studies ; Humans ; Tertiary Care Centers
    Language English
    Publishing date 2021-03-26
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2021.03.036
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  3. Article ; Online: Progress of research on coronaviruses and toroviruses in large domestic animals using reverse genetics systems.

    Ujike, Makoto / Suzuki, Tohru

    Veterinary journal (London, England : 1997)

    2024  , Page(s) 106122

    Abstract: The generation of genetically engineered recombinant viruses from modified DNA/RNA is commonly referred to as reverse genetics, which allows the introduction of desired mutations into the viral genome. Reverse genetics systems (RGSs) are powerful tools ... ...

    Abstract The generation of genetically engineered recombinant viruses from modified DNA/RNA is commonly referred to as reverse genetics, which allows the introduction of desired mutations into the viral genome. Reverse genetics systems (RGSs) are powerful tools for studying fundamental viral processes, mechanisms of infection, pathogenesis and vaccine development. However, establishing RGS for coronaviruses (CoVs) and toroviruses (ToVs), which have the largest genomes among vertebrate RNA viruses, is laborious and hampered by technical constraints. Hence, little research has focused on animal CoVs using RGSs, especially in large domestic animals such as pigs and cattle. In the last decade, however, studies of porcine CoVs and bovine ToVs using RGSs have been reported. In addition, the coronavirus disease-2019 pandemic has prompted the development of new and simple CoV RGSs, which will accelerate RGS-based research on animal CoVs and ToVs. In this review, we summarise the general characteristics of CoVs and ToVs, the RGSs available for CoVs and the progress made in the last decade in RGS-based research on porcine CoVs and bovine ToVs.
    Language English
    Publishing date 2024-04-17
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 428614-5
    ISSN 1532-2971 ; 0372-5545 ; 1090-0233
    ISSN (online) 1532-2971
    ISSN 0372-5545 ; 1090-0233
    DOI 10.1016/j.tvjl.2024.106122
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  4. Article: [Two Rare Resected Cases of Left Upper Lobe Infectious Nodule:Video-assisted Thoracic Surgery or Open Thoracotomy].

    Suzuki, Makoto

    Kyobu geka. The Japanese journal of thoracic surgery

    2021  Volume 74, Issue 7, Page(s) 528–532

    Abstract: Lobectomy for infectious nodules with suspected adhesion is depressing. Initially, we start the surgery through a thoracoscopic approach, but for unavoidable reasons, we sometimes convert it to an open thoracotomy. Here we experienced two rare resected ... ...

    Abstract Lobectomy for infectious nodules with suspected adhesion is depressing. Initially, we start the surgery through a thoracoscopic approach, but for unavoidable reasons, we sometimes convert it to an open thoracotomy. Here we experienced two rare resected cases of left upper lobe infectious nodule. We completed the left upper lobectomies with a thoracoscopic approach for one case and with an open thoracotomy for another. I will mainly report on the techniques of both approaches.
    MeSH term(s) Humans ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/surgery ; Pneumonectomy ; Thoracic Surgery, Video-Assisted ; Thoracotomy
    Language Japanese
    Publishing date 2021-07-01
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 603899-2
    ISSN 0021-5252
    ISSN 0021-5252
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  5. Article: [Lung Cancer Resection with Large Vessel Invasion and Its Perioperative Management].

    Suzuki, Makoto

    Kyobu geka. The Japanese journal of thoracic surgery

    2020  Volume 73, Issue 10, Page(s) 824–828

    Abstract: In case of direct invasion to the large vessel of lung cancer, combined resection of the involved lobe and the large vessel with its reconstruction are needed for complete resection. It is most important to secure the center side of the invaded blood ... ...

    Abstract In case of direct invasion to the large vessel of lung cancer, combined resection of the involved lobe and the large vessel with its reconstruction are needed for complete resection. It is most important to secure the center side of the invaded blood vessel during this operation. The approach to thoracic cavity is decided according to the approach of the center side of the invaded vessel. The cases of invasion to superior vena cava, subclavian artery, pulmonary artery, and pulmonary vein are discussed. The method of securing and clamping the above vessels are also important in case of injury of these vessels during surgery. After clamping the center side of the injured vessel, blood flow will be decreased and repairing the vessel will be accomplished with calm. Therefore, the method of securing the center side of the vessels is a technique should to be mastered for all thoracic surgeons.
    MeSH term(s) Humans ; Lung Neoplasms/surgery ; Neoplasm Invasiveness ; Pulmonary Surgical Procedures ; Vena Cava, Superior
    Language Japanese
    Publishing date 2020-10-22
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 603899-2
    ISSN 0021-5252
    ISSN 0021-5252
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  6. Article ; Online: Generation of Specific Aptamers.

    Liu, Shuang / Suzuki, Yasuyuki / Inui, Makoto

    Methods in molecular biology (Clifton, N.J.)

    2024  Volume 2766, Page(s) 129–137

    Abstract: Nucleic acid aptamers are therapeutic agents consisting of short single-strand DNA or RNA oligonucleotides, which have the ability to bind to target therapeutic molecules with high affinity and specificity and have been developed as potent drugs for the ... ...

    Abstract Nucleic acid aptamers are therapeutic agents consisting of short single-strand DNA or RNA oligonucleotides, which have the ability to bind to target therapeutic molecules with high affinity and specificity and have been developed as potent drugs for the treatment of rheumatoid arthritis. Aptamers have unique and advantageous features over antibodies, such as superior affinity with nano- or pico-molar dissociation constants and ease of chemical synthesis, modification, and inactivation by designing antisense sequences. In this chapter, using a DNA-oligonucleotide pool, the technology of proteoliposome-systematic evolution of ligands by exponential enrichment (SELEX) is introduced. By using this technique, potential therapeutic agents with high affinity and specificity could be obtained.
    MeSH term(s) Humans ; Antibodies ; Arthritis, Rheumatoid ; DNA, Single-Stranded ; Molar ; Oligonucleotides
    Chemical Substances Antibodies ; DNA, Single-Stranded ; Oligonucleotides
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3682-4_13
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  7. Article: Tracheostomy for the pediatric patient with fibrodysplasia ossificans progressiva: a case report.

    Kobayashi, Megumi / Hirai, Misako / Suzuki, Makoto / Sasaki, Akira

    Surgical case reports

    2024  Volume 10, Issue 1, Page(s) 61

    Abstract: Background: Fibrodysplasia ossificans progressiva (FOP) is an extremely rare connective tissue disease characterized by subsequent ossification of skeletal muscles, tendons, ligaments, and other fibrous tissues. The ossification of these tissues ... ...

    Abstract Background: Fibrodysplasia ossificans progressiva (FOP) is an extremely rare connective tissue disease characterized by subsequent ossification of skeletal muscles, tendons, ligaments, and other fibrous tissues. The ossification of these tissues progresses during childhood and leads to limb and trunk deformities. Since any surgery may trigger subsequent ossification, it is relatively contraindicated for patients with FOP. In this report, we describe our experience in performing tracheostomy in a pediatric patient with FOP who developed a restrictive respiratory disorder due to progressive deformity of the trunk.
    Case presentation: A 12-year-old boy, diagnosed with FOP at the age of one, was referred for a tracheotomy after requiring 2 months of oral intubation and mechanical ventilation due to severe deformity-induced dyspnea. After changing from oral intubation to nasal intubation, we carefully considered the indications and benefits of tracheostomy in patients with FOP. Eventually, tracheostomy was successfully performed using our surgical design: creating a skin incision at the level of the cricoid cartilage that can always be identified, creating inverted U-shaped incision on the anterior tracheal wall to make a flap, and suturing the entire circumference of the tracheotomy and skin. One month after the surgery, he regained normal breathing and pronunciation and returned to school. The patient showed no unfavorable postoperative outcomes over a 4-year follow-up period.
    Conclusions: Tracheostomy in our pediatric case of FOP required careful perioperative management. However, it could effectively improve the patient's quality of life.
    Language English
    Publishing date 2024-03-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2809613-7
    ISSN 2198-7793
    ISSN 2198-7793
    DOI 10.1186/s40792-024-01864-3
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  8. Article ; Online: Changes in the excitability of anterior horn cells in a mental rotation task of body parts.

    Nomura, Makoto / Aoyagi, Yoichiro / Suzuki, Toshiaki

    Muscle & nerve

    2024  Volume 69, Issue 5, Page(s) 643–646

    Abstract: Introduction/aims: Mental rotation (MR), a tool of implicit motor imagery, is the ability to rotate mental representations of two- or three-dimensional objects. Although many reports have described changes in brain activity during MR tasks, it is not ... ...

    Abstract Introduction/aims: Mental rotation (MR), a tool of implicit motor imagery, is the ability to rotate mental representations of two- or three-dimensional objects. Although many reports have described changes in brain activity during MR tasks, it is not clear whether the excitability of anterior horn cells in the spinal cord can be changed. In this study, we examined whether MR tasks of hand images affect the excitability of anterior horn cells using F-wave analysis.
    Methods: Right-handed, healthy participants were recruited for this study. F-waves of the right abductor pollicis brevis were recorded after stimulation of the right median nerve at rest, during a non-MR task, and during an MR task. The F-wave persistence and the F/M amplitude ratio were calculated and analyzed.
    Results: Twenty participants (11 men and 9 women; mean age, 29.2 ± 4.4 years) were initially recruited, and data from the 18 that met the inclusion criteria were analyzed. The F-wave persistence was significantly higher in the MR task than in the resting condition (p = .001) or the non-MR task (p = .012). The F/M amplitude ratio was significantly higher in the MR task than in the resting condition (p = .019).
    Discussion: The MR task increases the excitability of anterior horn cells corresponding to the same body part. MR tasks may have the potential for improving motor function in patients with reduced excitability of the anterior horn cells, although this methodology must be further verified in a clinical setting.
    MeSH term(s) Male ; Humans ; Female ; Young Adult ; Adult ; Anterior Horn Cells/physiology ; Human Body ; Muscle, Skeletal/physiology ; Spinal Cord ; Median Nerve/physiology ; Evoked Potentials, Motor/physiology ; Electromyography
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 438353-9
    ISSN 1097-4598 ; 0148-639X
    ISSN (online) 1097-4598
    ISSN 0148-639X
    DOI 10.1002/mus.28082
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  9. Article: [The Current Status of Standardizing Healthcare Information].

    Suzuki, Makoto

    Nihon Hoshasen Gijutsu Gakkai zasshi

    2018  Volume 74, Issue 9, Page(s) 1113–1115

    MeSH term(s) Delivery of Health Care ; Humans ; Information Services
    Language Japanese
    Publishing date 2018-09-20
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2269092-X
    ISSN 1881-4883 ; 0369-4305
    ISSN (online) 1881-4883
    ISSN 0369-4305
    DOI 10.6009/jjrt.2018_JSRT_74.9.1113
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  10. Article ; Online: Intranasal oxytocin suppresses seizure-like behaviors in a mouse model of NGLY1 deficiency.

    Makita, Yukimasa / Asahina, Makoto / Fujinawa, Reiko / Yukitake, Hiroshi / Suzuki, Tadashi

    Communications biology

    2024  Volume 7, Issue 1, Page(s) 460

    Abstract: NGLY1 deficiency is a genetic disease caused by biallelic mutations of the Ngly1 gene. Although epileptic seizure is one of the most severe symptoms in patients with NGLY1 deficiency, preclinical studies have not been conducted due to the lack of animal ... ...

    Abstract NGLY1 deficiency is a genetic disease caused by biallelic mutations of the Ngly1 gene. Although epileptic seizure is one of the most severe symptoms in patients with NGLY1 deficiency, preclinical studies have not been conducted due to the lack of animal models for epileptic seizures in NGLY1 deficiency. Here, we observed the behaviors of male and female Ngly1
    Language English
    Publishing date 2024-04-22
    Publishing country England
    Document type Journal Article
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-024-06131-7
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