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Article ; Online: Nursing management for temporary lodging facilities in Japan in the early stages of the COVID-19 pandemic: A multiple-case study.

Kida, Ryohei / Takemura, Yukie / Inoue, Maho / Ichikawa, Naoko / Koyanagi, Hiroe

2022 , Page(s) e12507

Abstract: Aim: Temporary lodging facilities which were non-medical facilities were established to secure beds for severely and moderately ill patients with COVID-19, as well as for isolation, non-contact observation, and care of mildly ill and asymptomatic ... ...

Abstract	Aim: Temporary lodging facilities which were non-medical facilities were established to secure beds for severely and moderately ill patients with COVID-19, as well as for isolation, non-contact observation, and care of mildly ill and asymptomatic patients in Japan. This study aims to understand nursing management practices adopted in these facilities by examining cases of their establishment and operation. Methods: A multiple-case study design was used. Interviews for qualitative data collection were conducted from August to October 2020. After analyzing the nursing management practices in four temporary lodging facilities, common points were collated and integrated. Results: For the establishment and operation of temporary lodging facilities, a three-layer structure based on disaster management methods was adopted: headquarters at the helm as overseers, field supervisors in the middle, and frontline nursing staff at the base. The structure had clear roles, facilitated information exchange, and provided efficient and effective nursing care. Field supervisors mainly provided psychological and clinical support for staff and served as information and interprofessional hubs. Conclusion: It is recommended that temporary lodging facilities should be organized based on principles of the division of labor. The workforce should comprise nursing staff, and experienced nursing professionals should be recruited to the higher echelons.
Language	English
Publishing date	2022-08-03
Publishing country	Japan
Document type	Journal Article
ZDB-ID	2156618-5
ISSN	1742-7924 ; 1742-7932
ISSN (online)	1742-7924
ISSN	1742-7932
DOI	10.1111/jjns.12507
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Article ; Online: Key strategies for managing nursing care under the COVID-19 pandemic: A multiple-case study of nursing directors.

Takemura, Yukie / Inoue, Maho / Ichikawa, Naoko / Kida, Ryohei / Koyanagi, Hiroe / Ikezaki, Sumie / Ikeda, Mari

Journal of nursing management

2022 Volume 30, Issue 8, Page(s) 4042–4053

Abstract: Aim: We aim to identify measures implemented by hospital nursing directors early in the COVID-19 pandemic and enabling factors.: Background: Managerial factors affect nurses' physical and mental health and willingness to work, especially early in a ... ...

Abstract	Aim: We aim to identify measures implemented by hospital nursing directors early in the COVID-19 pandemic and enabling factors. Background: Managerial factors affect nurses' physical and mental health and willingness to work, especially early in a pandemic. Method: We used multiple-case study of 15 hospitals, comparing management approaches by interviewing 28 nursing directors and their assistants from August to December 2020. Results: Hospitals that accepted COVID-19 patients and hospitals that unexpectedly experienced clusters underwent a nursing provision system organization phase, followed by an adjustment phase to maintain nursing organization function. Two factors aided measure implementation: an emergency system and staff protection policies. Conclusion: Early epidemic management strategies apply across contexts. The hospital's basic attitude is key to effective implementation of the strategies. Implications for nursing management: The results suggest that hospitals, nursing directors and nurses can each prepare for future emerging infectious disease epidemics.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Pandemics ; Hospitals ; Nursing Care
Language	English
Publishing date	2022-10-12
Publishing country	England
Document type	Journal Article
ZDB-ID	1162321-4
ISSN	1365-2834 ; 0966-0429
ISSN (online)	1365-2834
ISSN	0966-0429
DOI	10.1111/jonm.13844
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Article ; Online: Exploring nurses' clinical reasons for bed transfers in acute care wards: An observational study.

Tanaka, Shingo / Kunie, Keiko / Takemura, Yukie / Ichikawa, Naoko / Kida, Ryohei

Journal of nursing management

2021 Volume 29, Issue 7, Page(s) 2297–2306

Abstract: Aims: To investigate the number of bed transfers (patient transfers within the same ward) and their reasons in acute care wards of mid-sized hospitals with multibed and private rooms.: Background: Bed transfers, even when necessary, are burdensome ... ...

Abstract	Aims: To investigate the number of bed transfers (patient transfers within the same ward) and their reasons in acute care wards of mid-sized hospitals with multibed and private rooms. Background: Bed transfers, even when necessary, are burdensome for patients; however, the reasons for bed transfers in various types of rooms remain unclear. Methods: An observational study was conducted in seven wards in three hospitals in Japan. Nurses completed a questionnaire regarding each bed transfer, which elicited the reasons for the transfer. We classified transfer patterns based on the functions of the patients' rooms and the number of beds in each room and analysed scores. Results: Overall, 560 responses were analysed. The average number of bed transfers per day was 2.7. In total, 43% of bed transfers were conducted for patients aged over 70. The most frequent bed transfer pattern was 'transfer between patient rooms with the same number of beds', and the most frequent reason was 'patient did not need that bed'. Conclusions: Unnecessary bed transfers could be reduced by ward designs that reflect nurses' clinical judgement. Implications for nursing management: Monitoring data for the reason regarding bed transfer contributes to hospital planning and decreases unnecessary bed transfers.
MeSH term(s)	Aged ; Critical Care ; Hospitals ; Humans ; Nurses ; Patients' Rooms ; Surveys and Questionnaires
Language	English
Publishing date	2021-06-22
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	1162321-4
ISSN	1365-2834 ; 0966-0429
ISSN (online)	1365-2834
ISSN	0966-0429
DOI	10.1111/jonm.13352
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Article ; Online: Work-related communication mediates the relationship between perceived diversity climate and psychological empowerment among part-time nurses: A cross-sectional study.

Susuki, Tsuyoshi / Kida, Ryohei / Takemura, Yukie / Ichikawa, Naoko / Kunie, Keiko / Koyanagi, Hiroe

Journal of nursing management

2022 Volume 30, Issue 7, Page(s) 3041–3050

Abstract: Aim: This study investigates which work-related communication mediates the relationship between diversity climate and psychological empowerment among part-time nurses.: Background: Part-time nurses' high psychological empowerment is desirable because ...

Abstract	Aim: This study investigates which work-related communication mediates the relationship between diversity climate and psychological empowerment among part-time nurses. Background: Part-time nurses' high psychological empowerment is desirable because it may lead to high quality nursing practice. Methods: Anonymous self-report questionnaires or web-based surveys were used to measure diversity climate (Climate for Inclusion Scale), psychological empowerment (Japanese version of the Psychological Empowerment Scale) and work-related communication (scale developed in this study). The respondents were part-time nurses from departments with shift work in six Japanese hospitals having over 200 beds. The surveys were conducted from September to October 2020. Multiple regression analyses and a significance test of indirect effects were then conducted. Results: Among the work-related communication components, 'expressing thoughts about their work' fully mediated the relationship between diversity climate and psychological empowerment. Conclusions: It is important for part-time nurses to be actively 'expressing thoughts about their work' to enhance their psychological empowerment. Positive diversity climate is also important because it allows part-time nurses to express their thoughts regarding work. Implications for nursing management: Managers can enhance part-time nurses' psychological empowerment by encouraging them to express their work-related opinions based on the diversity climate.
Language	English
Publishing date	2022-06-28
Publishing country	England
Document type	Journal Article
ZDB-ID	1162321-4
ISSN	1365-2834 ; 0966-0429
ISSN (online)	1365-2834
ISSN	0966-0429
DOI	10.1111/jonm.13703
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Article: Inflammatory Cytokine-Induced HIF-1 Activation Promotes Epithelial-Mesenchymal Transition in Endometrial Epithelial Cells.

Hashimoto, Yoshiko / Tsuzuki-Nakao, Tomoko / Kida, Naoko / Matsuo, Yoshiyuki / Maruyama, Tetsuo / Okada, Hidetaka / Hirota, Kiichi

Biomedicines

2023 Volume 11, Issue 1

Abstract: The endometrium undergoes repeated proliferation and shedding during the menstrual cycle. Significant changes to this environment include fluctuations in the partial pressure of oxygen, exposure to a high-cytokine environment associated with intrauterine ...

Abstract	The endometrium undergoes repeated proliferation and shedding during the menstrual cycle. Significant changes to this environment include fluctuations in the partial pressure of oxygen, exposure to a high-cytokine environment associated with intrauterine infection, and inflammation. Chronic endometritis is a condition wherein mild inflammation persists in the endometrium and is one of the causes of implantation failure and miscarriage in early pregnancy. It is thought that the invasion of embryos into the endometrium requires epithelial-mesenchymal transition (EMT)-associated changes in the endometrial epithelium. However, the effects of inflammation on the endometrium remain poorly understood. In this study, we investigated the effects of the intrauterine oxygen environment, hypoxia-inducible factor (HIF), and inflammation on the differentiation and function of endometrial epithelial cells. We elucidated the ways in which inflammatory cytokines affect HIF activity and EMT in an immortalized cell line (EM-E6/E7/TERT) derived from endometrial epithelium. Pro-inflammatory cytokines caused significant accumulation of HIF-1α protein, increased HIF-1α mRNA levels, and enhanced hypoxia-induced accumulation of HIF-1α protein. The combined effect of inflammatory cytokines and hypoxia increased the expression of EMT-inducing factors and upregulated cell migration. Our findings indicate that pro-inflammatory factors, including cytokines and LPS, work synergistically with hypoxia to activate HIF-1 and promote EMT in endometrial epithelial cells.
Language	English
Publishing date	2023-01-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720867-9
ISSN	2227-9059
ISSN	2227-9059
DOI	10.3390/biomedicines11010210
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Article ; Online: The influence of learning circumstances and on-the-job opportunities for professional growth on perceived person-environment fit among hospital nurses: A longitudinal study.

Inoue, Maho / Kunie, Keiko / Takemura, Yukie / Kida, Ryohei / Ichikawa, Naoko

Journal of nursing management

2020 Volume 29, Issue 4, Page(s) 776–784

Abstract: Aims: The study aimed to determine the influence of learning circumstances (learning inside and outside hospitals, and communication about the nursing practice with colleagues) and on-the-job opportunities for professional growth on each dimension of ... ...

Abstract	Aims: The study aimed to determine the influence of learning circumstances (learning inside and outside hospitals, and communication about the nursing practice with colleagues) and on-the-job opportunities for professional growth on each dimension of person-environment fit (needs-supplies, demands-abilities, person-organisation and person-group fit) among nurses. Background: It is desirable for each dimension of person-environment fit to be high, as it links to many work-related outcomes. Methods: A longitudinal survey using a questionnaire was conducted in February 2019 (Time 1) and October 2019 (Time 2). A simple linear regression analysis and a multiple linear regression analysis were conducted, using data from 324 nurses. Results: The results of the simple regression analysis showed that three variables related to learning circumstances at Time 1 were positively related to each dimension of person-environment fit at Time 2. The multiple regression analysis showed on-the-job opportunities for professional growth at Time 1 related to person-environment fit at Time 2. Conclusions: To achieve high person-environment fit, nurses should be aware of on-the-job opportunities for professional growth. Implications for nursing management: To achieve high person-environment fit, nurse managers should evaluate nurses' abilities and assign them jobs that would help improve their nursing skills.
MeSH term(s)	Cross-Sectional Studies ; Hospitals ; Humans ; Job Satisfaction ; Longitudinal Studies ; Nurses ; Nursing Staff, Hospital ; Surveys and Questionnaires
Language	English
Publishing date	2020-12-24
Publishing country	England
Document type	Journal Article
ZDB-ID	1162321-4
ISSN	1365-2834 ; 0966-0429
ISSN (online)	1365-2834
ISSN	0966-0429
DOI	10.1111/jonm.13218
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Article: Synthesis, Properties, and Biodegradability of Thermoplastic Elastomers Made from 2-Methyl-1,3-propanediol, Glutaric Acid and Lactide.

Zahir, Lamya / Kida, Takumitsu / Tanaka, Ryo / Nakayama, Yuushou / Shiono, Takeshi / Kawasaki, Norioki / Yamano, Naoko / Nakayama, Atsuyoshi

Life (Basel, Switzerland)

2021 Volume 11, Issue 1

Abstract: An innovative type of biodegradable thermoplastic elastomers with improved mechanical properties from very common and potentially renewable sources, poly(L-lactide)- ...

Abstract	An innovative type of biodegradable thermoplastic elastomers with improved mechanical properties from very common and potentially renewable sources, poly(L-lactide)-
Language	English
Publishing date	2021-01-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662250-6
ISSN	2075-1729
ISSN	2075-1729
DOI	10.3390/life11010043
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Article ; Online: Extraction of the CDRH3 sequence of the mouse antibody repertoire selected upon influenza virus infection by subtraction of the background antibody repertoire.

Shingai, Masashi / Iida, Sayaka / Kawai, Naoko / Kawahara, Mamiko / Sekiya, Toshiki / Ohno, Marumi / Nomura, Naoki / Handabile, Chimuka / Kawakita, Tomomi / Omori, Ryosuke / Yamagishi, Junya / Sano, Kaori / Ainai, Akira / Suzuki, Tadaki / Ohnishi, Kazuo / Ito, Kimihito / Kida, Hiroshi

Journal of virology

2024 Volume 98, Issue 3, Page(s) e0199523

Abstract: Historically, antibody reactivity to pathogens and vaccine antigens has been evaluated using serological measurements of antigen-specific antibodies. However, it is difficult to evaluate all antibodies that contribute to various functions in a single ... ...

Abstract	Historically, antibody reactivity to pathogens and vaccine antigens has been evaluated using serological measurements of antigen-specific antibodies. However, it is difficult to evaluate all antibodies that contribute to various functions in a single assay, such as the measurement of the neutralizing antibody titer. Bulk antibody repertoire analysis using next-generation sequencing is a comprehensive method for analyzing the overall antibody response; however, it is unreliable for estimating antigen-specific antibodies due to individual variation. To address this issue, we propose a method to subtract the background signal from the repertoire of data of interest. In this study, we analyzed changes in antibody diversity and inferred the heavy-chain complementarity-determining region 3 (CDRH3) sequences of antibody clones that were selected upon influenza virus infection in a mouse model using bulk repertoire analysis. A decrease in the diversity of the antibody repertoire was observed upon viral infection, along with an increase in neutralizing antibody titers. Using kernel density estimation of sequences in a high-dimensional sequence space with background signal subtraction, we identified several clusters of CDRH3 sequences induced upon influenza virus infection. Most of these repertoires were detected more frequently in infected mice than in uninfected control mice, suggesting that infection-specific antibody sequences can be extracted using this method. Such an accurate extraction of antigen- or infection-specific repertoire information will be a useful tool for vaccine evaluation in the future. Importance: As specific interactions between antigens and cell-surface antibodies trigger the proliferation of B-cell clones, the frequency of each antibody sequence in the samples reflects the size of each clonal population. Nevertheless, it is extremely difficult to extract antigen-specific antibody sequences from the comprehensive bulk antibody sequences obtained from blood samples due to repertoire bias influenced by exposure to dietary antigens and other infectious agents. This issue can be addressed by subtracting the background noise from the post-immunization or post-infection repertoire data. In the present study, we propose a method to quantify repertoire data from comprehensive repertoire data. This method allowed subtraction of the background repertoire, resulting in more accurate extraction of expanded antibody repertoires upon influenza virus infection. This accurate extraction of antigen- or infection-specific repertoire information is a useful tool for vaccine evaluation.
MeSH term(s)	Animals ; Mice ; Antibodies, Neutralizing/blood ; Antibodies, Neutralizing/chemistry ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/blood ; Antibodies, Viral/chemistry ; Antibodies, Viral/immunology ; B-Lymphocytes/cytology ; B-Lymphocytes/immunology ; Clone Cells/cytology ; Clone Cells/immunology ; Complementarity Determining Regions/immunology ; Influenza Vaccines/immunology ; Orthomyxoviridae/immunology ; Orthomyxoviridae Infections/blood ; Orthomyxoviridae Infections/immunology ; Orthomyxoviridae Infections/virology
Chemical Substances	Antibodies, Neutralizing ; Antibodies, Viral ; Complementarity Determining Regions ; Influenza Vaccines
Language	English
Publishing date	2024-02-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	80174-4
ISSN	1098-5514 ; 0022-538X
ISSN (online)	1098-5514
ISSN	0022-538X
DOI	10.1128/jvi.01995-23
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Article: Cigarette Smoke Extract Activates Hypoxia-Inducible Factors in a Reactive Oxygen Species-Dependent Manner in Stroma Cells from Human Endometrium.

Kida, Naoko / Matsuo, Yoshiyuki / Hashimoto, Yoshiko / Nishi, Kenichiro / Tsuzuki-Nakao, Tomoko / Bono, Hidemasa / Maruyama, Tetsuo / Hirota, Kiichi / Okada, Hidetaka

Antioxidants (Basel, Switzerland)

2021 Volume 10, Issue 1

Abstract: Cigarette smoking (CS) is a major contributing factor in the development of a large number of fatal and debilitating disorders, including degenerative diseases and cancers. Smoking and passive smoking also affect the establishment and maintenance of ... ...

Abstract	Cigarette smoking (CS) is a major contributing factor in the development of a large number of fatal and debilitating disorders, including degenerative diseases and cancers. Smoking and passive smoking also affect the establishment and maintenance of pregnancy. However, to the best of our knowledge, the effects of smoking on the human endometrium remain poorly understood. In this study, we investigated the regulatory mechanism underlying CS-induced hypoxia-inducible factor (HIF)-1α activation using primary human endometrial stromal cells and an immortalized cell line (KC02-44D). We found that the CS extract (CSE) increased reactive oxygen species levels and stimulated HIF-1α protein stabilization in endometrial stromal cells, and that CS-induced HIF-1α-dependent gene expression under non-hypoxic conditions in a concentration- and time-dependent manner. Additionally, we revealed the upregulated expression of a hypoxia-induced gene set following the CSE treatment, even under normoxic conditions. These results indicated that HIF-1α might play an important role in CS-exposure-induced cellular stress, inflammation, and endometrial remodeling.
Language	English
Publishing date	2021-01-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704216-9
ISSN	2076-3921
ISSN	2076-3921
DOI	10.3390/antiox10010048
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Article ; Online: Synthesis, Properties, and Biodegradability of Thermoplastic Elastomers Made from 2-Methyl-1,3-propanediol, Glutaric Acid and Lactide

Lamya Zahir / Takumitsu Kida / Ryo Tanaka / Yuushou Nakayama / Takeshi Shiono / Norioki Kawasaki / Naoko Yamano / Atsuyoshi Nakayama

Life, Vol 11, Iss 1, p

2021 Volume 43

Abstract: An innovative type of biodegradable thermoplastic elastomers with improved mechanical properties from very common and potentially renewable sources, poly(L-lactide)- b -poly(2-methyl-1,3-propylene glutarate)- b -poly(L-lactide) (PLA- b -PMPG- b -PLA)s, ... ...

Abstract	An innovative type of biodegradable thermoplastic elastomers with improved mechanical properties from very common and potentially renewable sources, poly(L-lactide)- b -poly(2-methyl-1,3-propylene glutarate)- b -poly(L-lactide) (PLA- b -PMPG- b -PLA)s, has been developed for the first time. PLA- b -PMPG- b -PLAs were synthesized by polycondensation of 2-methyl-1,3-propanediol and glutaric acid and successive ring-opening polymerization of L-lactide, where PMPG is an amorphous central block with low glass transition temperature and PLA is hard semicrystalline terminal blocks. The copolymers showed glass transition temperature at lower than −40 °C and melting temperature at 130–152 °C. The tensile tests of these copolymers were also performed to evaluate their mechanical properties. The degradation of the copolymers and PMPG by enzymes proteinase K and lipase PS were investigated. Microbial biodegradation in seawater was also performed at 27 °C. The triblock copolymers and PMPG homopolymer were found to show 9–15% biodegradation within 28 days, representing their relatively high biodegradability in seawater. The macromolecular structure of the triblock copolymers of PLA and PMPG can be controlled to tune their mechanical and biodegradation properties, demonstrating their potential use in various applications.
Keywords	poly(L-lactide) ; triblock copolymers ; thermoplastic elastomer ; poly(2-methyl-1,3-propylene glutarate) ; biodegradability ; Science ; Q
Subject code	540
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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