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Article ; Online: État des lieux de la formation initiale de l’internat d’oncologie après la quatrième vague pandémie de la COVID-19 : une enquête AERIO-SFJRO.

Rousseau, Adrien / Laune, Quentin / Ollivier, Luc / Naoun, Natacha / Alexandre, Jérôme / Giraud, Philippe / Azria, David / Delaye, Matthieu

Bulletin du cancer

2022 Volume 109, Issue 7-8, Page(s) 834–843

Abstract: Background: COVID-19 pandemic troubled hospital and university's organization. Previous study showed oncology resident's formation has been impacted by pandemic. One year later, we aimed to evaluate the state of oncology resident's formation.: Methods! ...

Title translation	Formation of French oncology resident: A national survey.
Abstract	Background: COVID-19 pandemic troubled hospital and university's organization. Previous study showed oncology resident's formation has been impacted by pandemic. One year later, we aimed to evaluate the state of oncology resident's formation. Methods: We conducted a transversal study written by AERIO and SJRO, released via social networks and mail to the French oncology residents. Results: One hundred and sixty-four residents answered. Sixty-four (39%) were male and 99 (60.4%) were female, mean age was 26.8 years old, mean semester was 5.7. One hundred and five (64%) were medical oncologist and 53 (32.3%) were radiation oncologist. One hundred and forty residents (85.4%) had lectures during hospital internships, mainly in cancer center (77.1%) and academic hospitals (60.7%). One hundred and twenty-one residents (73.8%) had specialized diploma lectures, in 34.7% of case monthly. Respectively 42.7% and 18.3% of residents could access to their formation's day respectively rarely and never. Strengths of oncology residency were scientific dynamism (91.9%), clinical breadth (82%) and knowledge renewal (78.9%). Attractivity's obstacles to the residency were psychological arduousness (64%), administrative burden (48.2%) and too important worktime (47%). Conclusion: This survey shows the state of play of French oncology residency's formation at the end of 2021.
MeSH term(s)	Adult ; COVID-19/epidemiology ; Female ; Humans ; Internship and Residency ; Male ; Medical Oncology/education ; Pandemics ; Surveys and Questionnaires
Language	French
Publishing date	2022-06-04
Publishing country	France
Document type	Journal Article
ZDB-ID	213270-9
ISSN	1769-6917 ; 0007-4551
ISSN (online)	1769-6917
ISSN	0007-4551
DOI	10.1016/j.bulcan.2022.04.004
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Article ; Online: Tumeurs thyroïdiennes de l’adulte révélées par une paralysie laryngée unilatérale.

Alciato, Lauranne / Rubin, François / Villeneuve, Alexandre / La Croix, Candice / Bonfils, Pierre / Laccourreye, Ollivier

Presse medicale (Paris, France : 1983)

2019 Volume 48, Issue 9, Page(s) e267–e271

Abstract: Goal: To analyze the characteristic of thyroid tumor associated with ipsilateral unilateral laryngeal paralysis (ULP) in the adult patient.: Materials and methods: Retrospective analysis of a cohort of 30 patients with ULP related to an ipsilateral ... ...

Title translation	Thyroid tumors in the adult revealed by unilateral laryngeal paralysis.
Abstract	Goal: To analyze the characteristic of thyroid tumor associated with ipsilateral unilateral laryngeal paralysis (ULP) in the adult patient. Materials and methods: Retrospective analysis of a cohort of 30 patients with ULP related to an ipsilateral thyroid tumor (group A) and comparison with a cohort of 99 patients in whom ULP revealed a non-thyroid tumor (group B). Results: Group A consisted of 66.6% of women with a mean age of 69 years. Comparison between both groups noted that female gender was more frequent in group A (66.6% vs. 17.1%, P<0.0001), and the underlying tumor was more frequently malignant in group B (89.9% vs. 43.4%, P<0.0001). Within group A, the incidence for recovery of laryngeal motion varied form 0% for malignant tumor to 50% for benign tumor. In patients with a benign thyroid tumor in whom recovery of laryngeal motion did not occur, the watch policy initiated allowed to detect a pathology (malignant tumor or neurological) explaining persistent ULP in 57% of cases. Conclusion: The present series confirm that ULP in the face of thyroid tumor does not allow to distinguish formally between benign and malignant tumors and highlight the value of a long term watch policy in patients with benign thyroid tumor pathology in whom recovery of laryngeal mobility does not occur.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Deglutition Disorders/etiology ; Dysphonia/etiology ; Female ; Humans ; Male ; Middle Aged ; Recovery of Function ; Respiration Disorders/etiology ; Retrospective Studies ; Thyroid Neoplasms/complications ; Thyroid Neoplasms/surgery ; Treatment Outcome ; Vocal Cord Paralysis/etiology ; Vocal Cord Paralysis/surgery
Language	French
Publishing date	2019-08-27
Publishing country	France
Document type	Comparative Study ; Journal Article ; Review
ZDB-ID	120943-7
ISSN	2213-0276 ; 0032-7867 ; 0755-4982 ; 0301-1518
ISSN (online)	2213-0276
ISSN	0032-7867 ; 0755-4982 ; 0301-1518
DOI	10.1016/j.lpm.2019.07.036
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Book ; Online: Une requête lexicale pour capter les publications relatives à l’agriculture biologique dans ProdINRA

Ollivier, Guillaume

2019

Keywords	"Organics" in general
Publisher	HAL CCSD
Publishing country	dk
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: La place du bois dans l’architecture à Augustonemetum/Clermont-Ferrand

François Blondel / Damien Martinez / Julien Ollivier

Pallas, Vol 110, Pp 51-

les sites de la rue Fontgiève et de la Scène nationale (ier-iiie s. apr. J.-C.)

2019 Volume 67

Abstract: Two recent preventive excavations carried out in the centre of Clermont-Ferrand (Puy-de-Dôme) allowed to study the evolution of districts located in the outskirts of Augustonemetum, during the Early Roman Empire. The humidity of the ground ensured the ... ...

Abstract	Two recent preventive excavations carried out in the centre of Clermont-Ferrand (Puy-de-Dôme) allowed to study the evolution of districts located in the outskirts of Augustonemetum, during the Early Roman Empire. The humidity of the ground ensured the conservation of many timbers and allows to understand the place of this material in the urban architecture of the chief town of Arverni’s territory. The diversity of observed spaces and the variety of contexts (hostel, domus, craft workshops, place of worship) offer a first approach of the construction techniques, on the one hand thanks to the analysis of the various types of assemblages employed and of architectural devices, and, on the other hand, through the study of the strategies of supply and of management of wooden resources.
Keywords	wood ; architecture ; Early Roman Empire ; Augustonemetum/Clermont-Ferrand ; floor ; door sill ; Social Sciences ; H
Subject code	720
Language	French
Publishing date	2019-08-01T00:00:00Z
Publisher	Presses universitaires du Midi
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Impact du premier mois de confinement Covid 19 sur l’activité chirurgicale carcinologique des services universitaires d’otorhinolaryngologie en Ile de France

Laccourreye, Ollivier / Mirghani, Haitham / Evrard, Diane / Bonnefont, Pierre / Brugel, Lydia / Tankere, Frederic / Coste, André / Barry, Beatrix / Baujat, Bertrand / Atallah, Sarah / Kania, Romain

Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale

Abstract: Résumé Objectif: Evaluation de l’impact du premier mois de confinement lors de l’épidémie Covid 19 ... sur l’activité de chirurgie carcinologique des services universitaires d’otorhinolaryngologie en Ile ... Groupe A) et suivant (Groupe B) le confinement instauré le 17/03/2020 Objectif principal: évaluer l ...

Abstract	Résumé Objectif: Evaluation de l’impact du premier mois de confinement lors de l’épidémie Covid 19 sur l’activité de chirurgie carcinologique des services universitaires d’otorhinolaryngologie en Ile de France Matériel et Méthodes: Etude observationnelle, prospective, multicentrique menée au sein de 6 services universitaires (Paris Centre, Nord, Est et Sorbonne) d’otorhinolaryngologie sur le mois précédant (Groupe A) et suivant (Groupe B) le confinement instauré le 17/03/2020 Objectif principal: évaluer l’impact sur l’activité carcinologique chirurgicale Objectifs secondaires: évaluer les caractéristiques de la population, les modalités pratiques des interventions, les suites opératoires, l’évolution Covid des patients et des otorhinolaryngologistes et les effets néfastes Résultats: 224 interventions étaient réalisées Une diminution de 10,9 % de l’activité était notée, sans différence significative entre les services Les carcinomes épidermoïdes et la localisation au niveau du larynx, de l’hypopharynx, de l’oropharynx, de la cavité buccale, des fosses nasales et sinus de la face prédominaient, avec respectivement 79 % et 75,8 % des interventions, sans différence significative entre les groupes Les tumeurs classées T3/4 et N2/3 étaient plus fréquentes au sein du Groupe B (p = 0,002 et 0,0004) Il n’existait pas de différence significative entre les groupes en terme d’abord chirurgical, de modalités de reconstruction, de suites opératoires et de durée de séjour en soins intensifs ou en réanimation, de trachéotomie, de sonde naso-gastrique et d’hospitalisation Aucun patient n’était testé positif pour la Covid 19 au sein du Groupe A pour trois au sein du Groupe B, sans effets néfastes Les otorhinolaryngologistes qui participaient aux interventions ne développaient pas de symptômes évocateurs d’une infestation par la Covid 19 Conclusion: Cette étude souligne que l’épidémie Covid 19 et le confinement n’ont que légèrement altéré la chaine diagnostique et thérapeutique chirurgicale des cancers pris en charge dans les services universitaires ORL d’Ile de France, conservant toutes les chances de survie, sans favoriser la diffusion du virus
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #592206
Database	COVID19

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Book: L' économie des matières premières

Giraud, Pierre-Noël / Ollivier, Timothée

(Repères : Économie ; 663)

2015

Author's details	Pierre-Noël Giraud, Timothée Ollivier
Series title	Repères : Économie ; 663
Keywords	Rohstoffwirtschaft ; Rohstoff ; Rohstoffspekulation ; Welt
Language	French
Size	128 Seiten, Illustrationen, 19 cm
Document type	Book
Note	Bibliogr. p. 123-124
ISBN	2707188093 ; 9782707188090
Database	ECONomics Information System

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Article ; Online: Behavioral avoidance and biological safety of vetiver oil and its constituents against Aedes aegypti (L.), Aedes albopictus (Skuse) and Culex quinquefasciatus Say

Jirod Nararak / Carole Di Giorgio / Kanutcharee Thanispong / Chutipong Sukkanon / Unchalee Sanguanpong / Valerie Mahiou-Leddet / Evelyne Ollivier / Theeraphap Chareonviriyaphap / Sylvie Manguin

Current Research in Insect Science, Vol 2, Iss , Pp 100044- (2022)

2022

Abstract: ... mosquitoes. Vitiveria zizanioides (L.) Nash essential oil and its constituents have demonstrated various ...

Abstract	Numerous plant-based repellents are widely used for personal protection against host-seeking mosquitoes. Vitiveria zizanioides (L.) Nash essential oil and its constituents have demonstrated various mosquito repellent activities. In this study, three chemical actions of vetiver oil and five constituents (terpinen-4-ol, α-terpineol, valencene, vetiverol and vetivone) were characterized against Aedes aegypti, Aedes albopictus and Culex quinquefasciatus by using the high-throughput screening assay system (HITSS). Significant contact escape responses in Ae. aegypti and Ae. albopictus to all test compounds at concentrations between 2.5 and 5% were observed. Spatial repellency responses were also observed in some tested mosquito populations depending upon concentrations. The most significant toxic response on mosquitoes was found at the highest concentration, except for vetivone which had no toxic effect on Ae. aegypti and Ae. albopictus. Results on phototoxic and genotoxic hazard revealed that vetiver oil and their constituents showed no phototoxic potential or any significant genotoxic response. In conclusion, vetiver oil and two constituents, valencene and vetiverol, are potentials as active ingredients for mosquito repellency and present no toxicity.
Keywords	Plant-based repellent ; contact irritancy ; spatial repellent ; cytotoxicity ; mosquito vectors ; terpinen-4-ol ; Zoology ; QL1-991
Subject code	333
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: New sesquiterpene acid and inositol derivatives from Inula montana L.

Garayev, Elnur / Herbette, Gaëtan / Di Giorgio, Carole / Chiffolleau, Philippe / Roux, David / Sallanon, Huguette / Ollivier, Evelyne / Elias, Riad / Baghdikian, Béatrice

Fitoterapia

2017 Volume 120, Page(s) 79–84

Abstract: A phytochemical investigation of the ethanol extract of leaves and flowers of Inula montana L. led ...

Abstract	A phytochemical investigation of the ethanol extract of leaves and flowers of Inula montana L. led to the isolation of one new sesquiterpene acid called Eldarin (1) and four new inositol derivatives, Myoinositol,1,5-diangelate-4,6-diacetate (2), Myoinositol,1,6-diangelate-4,5-diacetate (3), Myoinositol-1-angelate-4,5-diacetate-6-(2-methylbutirate) (4), Myoinositol-1-angelate-4,5-diacetate-6-isovalerate (5) isolated for the first time, along with eleven known compounds described for the first time in Inula montana, 1β-Hydroxyarbusculin A (6), Artemorin (7), Santamarin (8), Chrysosplenol C (9), 6-Hydroxykaempferol 3,7-dimethyl ether (10), Reynosin (11), Calenduladiol-3-palmitate (12), Costunolide (13), 4-Hydroxy-3,5-dimethoxybenzenemethanol (14), 9β-Hydroxycostunolide (15) and Hispidulin (16). Structural elucidation has been carried out by spectral methods, such as 1D and 2D NMR, IR, UV and HR-ESI-MS. These compounds have been tested in vitro for anti-inflammatory and cytotoxic activity on macrophages RAW 264.7. As a result, compounds 2, 3, 7, 13, 14, 15 and 16 showed a release of NO with IC
MeSH term(s)	Animals ; Anti-Inflammatory Agents/isolation & purification ; Anti-Inflammatory Agents/pharmacology ; Flowers/chemistry ; Inositol/isolation & purification ; Inositol/pharmacology ; Inula/chemistry ; Macrophages/drug effects ; Mice ; Molecular Structure ; Nitric Oxide/metabolism ; Plant Leaves/chemistry ; RAW 264.7 Cells ; Sesquiterpenes/isolation & purification ; Sesquiterpenes/pharmacology
Chemical Substances	Anti-Inflammatory Agents ; Sesquiterpenes ; Nitric Oxide (31C4KY9ESH) ; Inositol (4L6452S749)
Language	English
Publishing date	2017-07
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	412385-2
ISSN	1873-6971 ; 0367-326X
ISSN (online)	1873-6971
ISSN	0367-326X
DOI	10.1016/j.fitote.2017.05.011
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Article: Impact de l’épidémie SARS-CoV-2 sur les consultations libérales d’otorhinolaryngologie lors du premier mois de confinement de l’île de la Réunion en 2020

Rubin, François / Vellin, Jean-François / Berkaoui, Julie / Assaf, Wared Al / Pennica, Angelo / Girard, Benoit / Hoarau, Patrick / Pescatori, Philippe / Dupre, Marie / Bensoussan, Serge / Vurpillot, Philippe / Challut, Nicolas / Laccourreye, Ollivier

Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale

Abstract: Résumé Objectif: Analyse de l’impact du premier mois de confinement lié à l’épidémie SARS-CoV-2 ... sur l’activité de consultation des otorhinolaryngologistes libéraux de l‘île de La Réunion Méthode ... Etude observationnelle, multicentrique, prospective analysant l’activité de consultation de douze ...

Abstract	Résumé Objectif: Analyse de l’impact du premier mois de confinement lié à l’épidémie SARS-CoV-2 sur l’activité de consultation des otorhinolaryngologistes libéraux de l‘île de La Réunion Méthode: Etude observationnelle, multicentrique, prospective analysant l’activité de consultation de douze praticiens Objectif principal: évaluer le nombre, les caractéristiques et les modalités des consultations réalisées Objectifs secondaires: préciser les symptômes amenant les patients à consulter, les diagnostics évoqués, les prescriptions instaurées, les éventuelles conséquences néfastes et l’impact sur le chiffre d‘affaire Résultats: 693 consultations étaient réalisées, don’t 50% étaient demandées en urgence 57,9 % des consultations étaient réalisées en présence du patient, 28,4% étaient effectuées au téléphone et 13,7% et en téléconsultation Lors des consultations présentielles, les otorhinolaryngologistes portaient des gants et un masque respectivement dans 53,8% et 92,2% des cas Le masque porté était de type chirurgical et de type FFP2 dans 71,6 % et 28,4 % de cas, respectivement Les trois symptômes les plus fréquents (48,5% des cas) étaient l’otalgie, les troubles de l’audition et les vertiges Les trois diagnostics les plus fréquents (60 6 % des cas) étaient, les otites, les corps étrangers d’oreille (cérumen inclus) et les infections pharyngées Les trois examens complémentaires les plus prescrits (74 3% des cas) étaient l’imagerie, l’audiométrie, et l’avis d’un spécialiste médical Les trois familles thérapeutiques les plus prescrites (52 7 % des cas) étaient les gouttes auriculaires, les antibiotiques, et les lavages de nez et/ou sprays nasaux L’incidence des conséquences néfastes était de 0,001 % et aucun des otorhinolaryngologistes ou des patients ne semblait avoir été infecté par la Covid 19 Une baisse de 47,3 % à 91 % (médiane : 75,6 %) du chiffre d’affaire de consultation était notée Conclusion: Cette étude souligne la disponibilité et l’adaptabilité des ORL réunionnais libéraux en contexte épidémique malgré un impact économique très négatif
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #603935
Database	COVID19

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Article ; Online: Dimeric bisindole alkaloids from the stem bark of Strychnos nux-vomica L.

Jonville, Marie-Caroline / Dive, Georges / Angenot, Luc / Bero, Joanne / Tits, Monique / Ollivier, Evelyne / Frédérich, Michel

Phytochemistry

2013 Volume 87, Page(s) 157–163

Abstract: Strychnos nux-vomica L. (Loganiaceae) is famous for its monomeric alkaloid content ...

Abstract	Strychnos nux-vomica L. (Loganiaceae) is famous for its monomeric alkaloid content, such as strychnine, a convulsant poison. The stem bark of the tree is traditionally used to treat intermittent fever in South East Asia. In various studies, it appeared that dimeric indolo-monoterpenic alkaloids possess a promising activity on Plasmodium falciparum. Three bisindolomonoterpenic alkaloids together with strychnochrysine, previously identified in the root bark of S. nux-vomica, were isolated from the stem bark. The structures of these compounds were established using NMR spectroscopy and mass spectrometry. Stereochemistry of the compounds was confirmed by molecular modelling. This then allowed the structural determination of strychnoflavine, a coloured bisindole alkaloid previously isolated from the root bark of the tree. Moreover, the conformational inversion in alkaloids possessing an ether bond in the strychnane moiety could be easily predicted by specific δ (13)C NMR values. These longicaudatine-type alkaloids were found to display in vitro antiplasmodial activity against a chloroquine resistant strain and a chloroquine sensitive strain. The most interesting was strychnochrysine showing an IC(50) value at around 10 μM.
MeSH term(s)	Alkaloids/chemistry ; Alkaloids/pharmacology ; Animals ; Antimalarials/chemistry ; Antimalarials/pharmacology ; Humans ; Magnetic Resonance Spectroscopy ; Mass Spectrometry ; Plant Bark/chemistry ; Plant Stems/chemistry ; Plasmodium falciparum/drug effects ; Strychnos nux-vomica/chemistry
Chemical Substances	Alkaloids ; Antimalarials
Language	English
Publishing date	2013-03
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	208884-8
ISSN	1873-3700 ; 0031-9422
ISSN (online)	1873-3700
ISSN	0031-9422
DOI	10.1016/j.phytochem.2012.11.002
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