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  1. Article ; Online: Reflections upon the intrauterine repair of myelomeningocele.

    Talamonti, Giuseppe

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2024  Volume 40, Issue 5, Page(s) 1571–1575

    Abstract: The intrauterine repair of myelomeningocele presents certain advantages and has gained widespread acceptance. It significantly reduces the incidence of Chiari-2 anomalies and hydrocephalus, and it is thought to enhance the neurologic outcome. ... ...

    Abstract The intrauterine repair of myelomeningocele presents certain advantages and has gained widespread acceptance. It significantly reduces the incidence of Chiari-2 anomalies and hydrocephalus, and it is thought to enhance the neurologic outcome. Nevertheless, several issues remain unsettled and there are no negligible disadvantages. After working with patients with myelomeningocele for 30 years, I thought about how we currently treat them. There are ethical, organizational, neurological, obstetrical, and postnatal aspects worth discussing.
    MeSH term(s) Humans ; Meningomyelocele/surgery ; Arnold-Chiari Malformation/complications ; Hydrocephalus/surgery ; Incidence
    Language English
    Publishing date 2024-03-22
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-024-06365-0
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    Zs.A 2036: Show issues Location:
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  2. Article ; Online: PEG hydrogel sealant versus fibrin glue in posterior fossa surgery: an economic comparison across five European countries.

    Talamonti, Giuseppe / Horaczek, Jörn-Andre / Torres, Rafael Torrejon / Deppo, Lisa Da / Carter, Marissa J

    Journal of comparative effectiveness research

    2024  Volume 13, Issue 4, Page(s) e230047

    Abstract: Aim: ...

    Abstract Aim:
    MeSH term(s) Humans ; Fibrin Tissue Adhesive/therapeutic use ; Neurosurgical Procedures/adverse effects ; Neurosurgical Procedures/methods ; Cerebrospinal Fluid Leak/prevention & control ; Cerebrospinal Fluid Leak/etiology ; Cerebrospinal Fluid Rhinorrhea/etiology ; Cerebrospinal Fluid Rhinorrhea/prevention & control ; Postoperative Complications/epidemiology ; Hydrogels
    Chemical Substances Fibrin Tissue Adhesive ; Hydrogels
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2669725-7
    ISSN 2042-6313 ; 2042-6305
    ISSN (online) 2042-6313
    ISSN 2042-6305
    DOI 10.57264/cer-2023-0047
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  3. Article ; Online: In Reply: COVID-19 Infection Affects Surgical Outcome of Chronic Subdural Hematoma.

    Talamonti, Giuseppe / D'Aliberti, Giuseppe / Cenzato, Marco

    Neurosurgery

    2020  Volume 87, Issue 2, Page(s) E172

    Keywords covid19
    Language English
    Publishing date 2020-05-05
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1093/neuros/nyaa210
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  4. Article ; Online: Chiari malformation type 1: are we doing less with more? Illustrative case.

    Talamonti, Giuseppe / Ferrari, Erika / D'Aliberti, Giuseppe

    Journal of neurosurgery. Case lessons

    2021  Volume 1, Issue 6, Page(s) CASE20145

    Abstract: Background: Classic treatment of Chiari malformation type 1 consists of foramen magnum decompression. Selected patients may require occipitocervical fixation, transoral odontoidectomy, tonsillectomy, and so forth. Treatment standardization does not yet ... ...

    Abstract Background: Classic treatment of Chiari malformation type 1 consists of foramen magnum decompression. Selected patients may require occipitocervical fixation, transoral odontoidectomy, tonsillectomy, and so forth. Treatment standardization does not yet exist, and some patients risk being overtreated.
    Observations: A 20-year-old man with headache and Chiari malformation type 1 underwent extradural bone decompression. One year later, he was managed with the extradural section of his filum terminale. Eighteen months later, the patient underwent monitoring of intracranial pressure, occipitocervical stabilization, transoral odontoidectomy, minimally invasive subpial tonsillectomy, and occipital cranioplasty. His headache never changed, and he progressively developed hemiparesis and swallowing and respiratory disturbances. Two years later, a new magnetic resonance imaging scan showed extended syringomyelia with scarce peritonsillar subarachnoid space. The umpteenth operation consisted of the removal of a constricting epidural scar, arachnoid dissection, total tonsillectomy, creation of a wide subarachnoid space, and dural sac augmentation. The patient's initial postoperative course was smooth, and his headache improved. However, 8 days after surgery, the patient acutely presented with vegetative disturbances and died because of malignant brainstem edema of unknown origin.
    Lessons: The story of this patient is not so uncommon. He underwent all the possible surgical treatments rather than a timely adequate osteodural decompression. Probably, he received less with more.
    Language English
    Publishing date 2021-02-08
    Publishing country United States
    Document type Case Reports
    ISSN 2694-1902
    ISSN (online) 2694-1902
    DOI 10.3171/CASE20145
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  5. Article ; Online: Dural arteriovenous fistula with varix: proposal as a subtype of spinal arteriovenous malformation type 1: a personal experience.

    D'Aliberti, Giuseppe A / Bosnjakovic, Petar / Al-Sheikh, Tarek / Crisà, Francesco M / Talamonti, Giuseppe / Jadik, Senol

    Journal of neurosurgical sciences

    2023  Volume 67, Issue 5, Page(s) 667–669

    MeSH term(s) Humans ; Arteriovenous Malformations/surgery ; Varicose Veins ; Central Nervous System Vascular Malformations/surgery
    Language English
    Publishing date 2023-05-11
    Publishing country Italy
    Document type Letter
    ZDB-ID 193139-8
    ISSN 1827-1855 ; 0390-5616 ; 0026-4881
    ISSN (online) 1827-1855
    ISSN 0390-5616 ; 0026-4881
    DOI 10.23736/S0390-5616.23.06046-0
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  6. Article: Reoperation in Chiari-1 Malformations.

    Talamonti, Giuseppe / Picano, Marco / Fragale, Maria / Marcati, Eleonora / Meccariello, Giulia / Boeris, Davide / Cenzato, Marco

    Journal of clinical medicine

    2023  Volume 12, Issue 8

    Abstract: 1) Background: The issue of unsuccessful surgery for Chiari-1 malformation (CM-1), as well as its potential causes and possible solutions, remains poorly documented and studied. (2) Methods: From a retrospective review of a personal series of 98 ... ...

    Abstract (1) Background: The issue of unsuccessful surgery for Chiari-1 malformation (CM-1), as well as its potential causes and possible solutions, remains poorly documented and studied. (2) Methods: From a retrospective review of a personal series of 98 patients undergoing treatment for CM-1 during the past 10 years, we created two study groups. Group 1: 8 patients (8.1%) requiring additional surgeries owing to postoperative complications (7 cerebrospinal fluid leakage, 1 extradural hematoma); 7 patients (7.1%) undergoing reoperations for failed decompression during the follow-up. Group 2: During the same period, we also managed 19 patients who had previously been operated on elsewhere: 8 patients who required adequate CM-1 treatment following extradural section of the filum terminale; 11 patients requiring reoperations for failed decompression. Failed decompression was managed by adequate osteodural decompression, which was associated with tonsillectomy (6 cases), subarachnoid exploration (8 cases), graft substitution (6 cases), and occipito-cervical fixation/revision (1 case). (3) Results: There was no mortality or surgical morbidity in Group 1. However, one patient's condition worsened due to untreatable syrinx. In Group 2, there were two cases of mortality, and surgical morbidity was represented by functional limitation and pain in the patient who needed revision of the occipitocervical fixation. Twenty patients improved (58.8%), 6 remained unchanged (32.3%), 1 worsened (2.9%) and 2 died (5.9%). (4) Conclusions: The rate of complications remains high in CM-1 treatment. Unfortunately, a certain rate of treatment failure is unavoidable, but it appears that a significant number of re-operations could have been avoided using proper indications and careful technique.
    Language English
    Publishing date 2023-04-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12082853
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  7. Article ; Online: Surgical Treatment of Complex Craniofacial Fractures.

    Talamonti, Giuseppe / Fragale, Maria / Carrassi, Erika / Meccariello, Giulia / Pozza, Alessandro / Canzi, Gabriele

    World neurosurgery

    2023  Volume 183, Page(s) e462–e469

    Abstract: Objective: Severe craniofacial fractures may present different needs in treating intracranial lesions over facial injuries. This paper examines the results of our strategy, consisting of a single-stage combined neurosurgical-maxillofacial treatment.: ... ...

    Abstract Objective: Severe craniofacial fractures may present different needs in treating intracranial lesions over facial injuries. This paper examines the results of our strategy, consisting of a single-stage combined neurosurgical-maxillofacial treatment.
    Methods: A retrospective review was conducted of 33 consecutive patients with complex fractures of the anterior cranial fossa and facial skeleton, who required elective surgery for craniofacial reconstruction. Patients who required emergency surgery for intracranial clots or penetrating wounds were excluded. In all cases, all or almost all the anterior skull-base was injured with compound fractures of the frontal sinus, the orbital roofs, the lamina cribrosa, and the planum sphenoidale. In all cases, the prioritization of treatment was carefully discussed, and surgical timing and strategy were agreed.
    Results: There was 1 dead. Olfactory injuries were always found intraoperatively. There were no mucoceles, CSF-leak recurrences, cranial infections, or neurologic worsening. The functional and neurologic results were highly satisfactory.
    Conclusions: The one-stage surgical treatment of complex craniofacial fractures has numerous advantages, including the possibility of reducing facial fractures without the risk of CSF leaks. It also eliminates the need for repeated procedures in fragile patients, and the need to dismantle the facial reconstruction if the skull base repair is performed later. The main issue is the surgical timing, considering that the maxillofacial surgeon usually favors early facial repair, whereas the neurosurgeon generally prefers delayed manipulation of the contused frontal lobes. A timeframe of 10-14 days after trauma may be a good compromise for safe procedures with excellent neurologic and functional outcomes.
    MeSH term(s) Humans ; Skull Base/surgery ; Skull Fractures/surgery ; Ethmoid Bone/surgery ; Plastic Surgery Procedures ; Cranial Fossa, Anterior/surgery
    Language English
    Publishing date 2023-12-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.12.121
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    Zs.A 1159: Show issues Location:
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  8. Article ; Online: Surgical pathway proposal for severe paralytic scoliosis in adolescents with myelomeningocele.

    Giorgi, Pietro Domenico / Schirò, Giuseppe Rosario / Capitani, Paolo / D'Aliberti, Giuseppe Antonio / Talamonti, Giuseppe

    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery

    2021  Volume 37, Issue 7, Page(s) 2279–2287

    Abstract: Purpose: The increased life expectancy of patients with myelomeningocele led to the necessity of new management for addressing complex spine deformities with severe pelvic obliquity. Tethered cord release (TCR) and spinal fusion were described as ... ...

    Abstract Purpose: The increased life expectancy of patients with myelomeningocele led to the necessity of new management for addressing complex spine deformities with severe pelvic obliquity. Tethered cord release (TCR) and spinal fusion were described as treatment options. However, nowadays, the surgical strategy is not well defined and high rates of mechanical failures and complications are reported. Our aim was to propose a new two-stage surgical pathway to treat a selected group of severe myelomeningocele scoliosis.
    Methods: This is a retrospective series of myelomeningocele scoliosis in paralytic adolescent patients treated with concurrent TCR and posterior spinal fusion (PSF), followed by delayed anterior fusion (ASF) through minimally invasive lateral approach. Inclusion criteria were as follows: evolutive scoliosis in tethered cord syndrome and paraplegia, main curve >70°, pelvic obliquity >20°, and age between 10 and 18 years. Clinical, surgical, and radiographic parameters were evaluated preoperatively and at a mean follow-up (FU) of 2.8 years.
    Results: Six patients out of 58 met the inclusion criteria and were included in the study (mean age 12.3 years old). The mean curve and pelvic obliquity correction were 68.8% and 82%, respectively. No loss of correction was recorded at FU. One case of cerebrospinal fluid leakage requiring revision surgery was recorded.
    Conclusion: To the best of our knowledge, this is the first study proposing a two-stage surgical pathway for severe MMC spinopelvic deformity treatment. Concurrent TCR and PSF with delayed minimally invasive ASF permitted to minimize complications providing good fusion rates without loss of correction and implant failure.
    MeSH term(s) Adolescent ; Child ; Humans ; Meningomyelocele/complications ; Meningomyelocele/diagnostic imaging ; Meningomyelocele/surgery ; Neural Tube Defects ; Retrospective Studies ; Scoliosis/complications ; Scoliosis/diagnostic imaging ; Spinal Fusion ; Treatment Outcome
    Language English
    Publishing date 2021-02-14
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 605988-0
    ISSN 1433-0350 ; 0302-2803 ; 0256-7040
    ISSN (online) 1433-0350
    ISSN 0302-2803 ; 0256-7040
    DOI 10.1007/s00381-021-05079-x
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  10. Article ; Online: Clinical considerations on a right operculo-insular cavernous angioma: an illustrative case.

    Marcati, Eleonora / Ferrari, Erika / Fava, Enrica / Talamonti, Giuseppe / D'Aliberti, Giuseppe A

    Acta neurochirurgica

    2021  Volume 163, Issue 10, Page(s) 2755–2759

    Abstract: The insular cortex is considered one of the most complex regions of the brain, defined as the "hub" of somatosensory areas. Here, we examine the case of a surgically treated haemorrhagic cavernoma involving the middle and posterior insular cortex, ... ...

    Abstract The insular cortex is considered one of the most complex regions of the brain, defined as the "hub" of somatosensory areas. Here, we examine the case of a surgically treated haemorrhagic cavernoma involving the middle and posterior insular cortex, presenting both sensory, gustative and speech symptoms. By reviewing the recent findings in humans' and primates' basic research, we illustrated clinical and radiological correlations of the reported case, confirming insular role in sensitive and gustatory functions.
    MeSH term(s) Animals ; Cerebral Cortex/diagnostic imaging ; Cerebral Cortex/surgery ; Hemangioma, Cavernous/diagnostic imaging ; Hemangioma, Cavernous/surgery ; Radiography
    Language English
    Publishing date 2021-08-07
    Publishing country Austria
    Document type Case Reports ; Journal Article
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-021-04947-4
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