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  1. Book ; Online ; E-Book: Feedback control for personalized medicine

    Hernandez-Vargas, Esteban A.

    2022  

    Author's details edited by Esteban A. Hernandez-Vargas
    Keywords Precision medicine
    Subject code 610.28
    Language English
    Size 1 online resource (309 pages)
    Publisher Academic Press
    Publishing place London, England
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-323-90665-6 ; 9780323901710 ; 978-0-323-90665-4 ; 0323901719
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Mathematical modeling, simulations, and AI for emergent pandemic diseases

    Hernandez-Vargas, Esteban A. / Velasco-Hernández, Jorge X.

    lessons learned from COVID-19

    2023  

    Author's details edited by Esteban A. Hernandez-Vargas, Jorge X. Velasco-Hernández
    Keywords Artificial intelligence/Medical applications ; COVID-19 (Disease)/Computer simulation ; COVID-19 (Disease)/Epidemiology/Mathematical models
    Subject code 610.285
    Language English
    Dates of publication 2023-2023
    Size 1 online resource (xvii, 331 pages) :, illustrations
    Publisher Academic Press
    Publishing place London, England
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-323-95065-5 ; 0-323-95064-7 ; 978-0-323-95065-7 ; 978-0-323-95064-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online ; E-Book: Modeling and control of infectious diseases in the host

    Hernandez-Vargas, Esteban A.

    with MATLAB and R

    2019  

    Author's details Esteban A. Hernandez-Vargas
    Keywords Communicable diseases/Mathematical models ; Numerical analysis/Computer programs ; R (Computer program language)
    Subject code 616.9015118
    Language English
    Size 1 Online-Ressource (xiii, 243 Seiten), Illustrationen
    Publisher Elsevier AP Academic Press
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020030551
    ISBN 978-0-12-813111-4 ; 9780128130520 ; 0-12-813111-X ; 0128130520
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Integrative Computational Systems Biology Approaches in Immunology and Medicine

    Kaderali, Lars / Theis, Fabian / Hernandez-Vargas, Esteban A. / Ganusov, Vitaly V. / Ciupe, Stanca M. / Mehr, Ramit / Ribeiro, Ruy

    2019  

    Keywords Science: general issues ; Medical microbiology & virology ; Microbiology (non-medical) ; mathematical modeling ; multiscale modeling ; systems biolgoy ; immunology ; infections
    Size 1 electronic resource (290 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021229854
    ISBN 9782889458011 ; 2889458016
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Confinement tonicity on epidemic spreading.

    Almocera, Alexis Erich S / González, Alejandro H / Hernandez-Vargas, Esteban A

    Journal of mathematical biology

    2024  Volume 88, Issue 4, Page(s) 46

    Abstract: Emerging and re-emerging pathogens are latent threats in our society with the risk of killing millions of people worldwide, without forgetting the severe economic and educational backlogs. From COVID-19, we learned that self isolation and quarantine ... ...

    Abstract Emerging and re-emerging pathogens are latent threats in our society with the risk of killing millions of people worldwide, without forgetting the severe economic and educational backlogs. From COVID-19, we learned that self isolation and quarantine restrictions (confinement) were the main way of protection till availability of vaccines. However, abrupt lifting of social confinement would result in new waves of new infection cases and high death tolls. Here, inspired by how an extracellular solution can make water move into or out of a cell through osmosis, we define confinement tonicity. This can serve as a standalone measurement for the net direction and magnitude of flows between the confined and deconfined susceptible compartments. Numerical results offer insights on the effects of easing quarantine restrictions.
    MeSH term(s) Humans ; SARS-CoV-2 ; COVID-19/epidemiology ; COVID-19/prevention & control ; Epidemics/prevention & control ; Quarantine
    Language English
    Publishing date 2024-03-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 187101-8
    ISSN 1432-1416 ; 0303-6812
    ISSN (online) 1432-1416
    ISSN 0303-6812
    DOI 10.1007/s00285-024-02064-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1495: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Editorial: Multiscale computational approaches in infectious diseases.

    Hernandez-Vargas, Esteban A / Velasco-Hernández, Jorge X / Bruder, Dunja

    Frontiers in microbiology

    2022  Volume 13, Page(s) 947673

    Language English
    Publishing date 2022-07-29
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.947673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online ; Thesis: Modelling of resistant infections between-host and within-host

    Tetteh, Josephine Naa Ayeley [Verfasser] / Hernandez-Vargas, Esteban A. [Akademischer Betreuer] / Crauel, Hans [Akademischer Betreuer] / Hernandez-Vargas, Esteban A. [Gutachter] / Crauel, Hans [Gutachter]

    2023  

    Author's details Josephine Naa Ayeley Tetteh ; Gutachter: Esteban Abelardo Hernandez-Vargas, Hans Crauel ; Esteban A. Hernández-Vargas, Hans Crauel
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language English
    Publisher Universitätsbibliothek Johann Christian Senckenberg
    Publishing place Frankfurt am Main
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  8. Book ; Online ; Thesis: Influenza a infections in the host

    Hernández Meji̐a, Gustavo [Verfasser] / Hernandez-Vargas, Esteban A. [Akademischer Betreuer] / Matthäus, Franziska [Gutachter]

    modeling and control approaches

    2024  

    Author's details Gustavo Hernandez Mejia ; Gutachter: Franziska Matthäus ; Betreuer: Esteban Abelardo Hernandez Vargas
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language English
    Publisher Universitätsbibliothek Johann Christian Senckenberg
    Publishing place Frankfurt am Main
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  9. Article: Modeling Kick-Kill Strategies toward HIV Cure.

    Hernandez-Vargas, Esteban A

    Frontiers in immunology

    2017  Volume 8, Page(s) 995

    Abstract: Although combinatorial antiretroviral therapy (cART) potently suppresses the virus, a sterile or functional cure still remains one of the greatest therapeutic challenges worldwide. Reservoirs are infected cells that can maintain HIV persistence for ... ...

    Abstract Although combinatorial antiretroviral therapy (cART) potently suppresses the virus, a sterile or functional cure still remains one of the greatest therapeutic challenges worldwide. Reservoirs are infected cells that can maintain HIV persistence for several years in patients with optimal cART, which is a leading obstacle to eradicate the virus. Despite the significant progress that has been made in our understanding of the diversity of cells that promote HIV persistence, many aspects that are critical to the development of effective therapeutic approaches able to purge the latent CD4+ T cell reservoir are poorly understood. Simultaneous purging strategies known as "kick-kill" have been pointed out as promising therapeutic approaches to eliminate the viral reservoir. However, long-term outcomes of purging strategies as well as the effect on the HIV reservoir are still largely fragmented. In this context, mathematical modeling can provide a rationale not only to evaluate the impact on the HIV reservoir but also to facilitate the formulation of hypotheses about potential therapeutic strategies. This review aims to discuss briefly the most recent mathematical modeling contributions, harnessing our knowledge toward the uncharted territory of HIV eradication. In addition, problems associated with current models are discussed, in particular, mathematical models consider only T cell responses but HIV control may also depend on other cell responses as well as chemokines and cytokines dynamics.
    Language English
    Publishing date 2017
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2017.00995
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Online: Human Trafficking in Mexico

    Tostado, Sofía de la Mora / Núñez-López, Mayra / Hernández-Vargas, Esteban A.

    Data sources, Network Analysis and the Limits of Dismantling Strategies

    2022  

    Abstract: Human trafficking is a heartless crime that represents the second most profitable crime in the world. Mexico's geographical position makes it a country with high levels of human trafficking. Using the snowball sampling method, the major contribution of ... ...

    Abstract Human trafficking is a heartless crime that represents the second most profitable crime in the world. Mexico's geographical position makes it a country with high levels of human trafficking. Using the snowball sampling method, the major contribution of this paper is the abstraction of the human trafficking network on the southern border of Mexico. Based on a social network analysis, it is identified that the criminal network is moderately centralized (44.32%) and with medium density (0.401). Therefore, the network has minimal cohesiveness and members may find it difficult to share information, money, or products among themselves. To evaluate different dismantling strategies to tackle the criminal organization, three algorithms are evaluated. We found that the first actors to be removed are neither the most connected nor the most peripheral, but the actors who are moderately connected to people of their kind should be removed. In summary, this paper provides a significant step forward to understand quantitatively human trafficking networks and evaluate the limits of dismantling strategies.
    Keywords Computer Science - Social and Information Networks ; Mathematics - Optimization and Control
    Publishing date 2022-06-06
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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