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  1. Article: Computational modeling of PET imaging agents for vesicular acetylcholine transporter (VAChT) protein binding affinity: application of 2D-QSAR modeling and molecular docking techniques.

    De, Priyanka / Roy, Kunal

    In silico pharmacology

    2023  Volume 11, Issue 1, Page(s) 9

    Language English
    Publishing date 2023-04-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2702993-1
    ISSN 2193-9616
    ISSN 2193-9616
    DOI 10.1007/s40203-023-00146-4
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  2. Article: Breeding Habitat Preference of the Dengue Vector Mosquitoes

    Herath, J M Manel K / De Silva, W A Priyanka P / Weeraratne, Thilini C / Karunaratne, S H P Parakrama

    Journal of tropical medicine

    2024  Volume 2024, Page(s) 4123543

    Abstract: Elimination of vector mosquito larvae and their breeding environments is an effective strategy in dengue disease control. Present study examined larval density and water quality in breeding habitats and container preference of dengue ... ...

    Abstract Elimination of vector mosquito larvae and their breeding environments is an effective strategy in dengue disease control. Present study examined larval density and water quality in breeding habitats and container preference of dengue vectors
    Language English
    Publishing date 2024-01-29
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2546526-0
    ISSN 1687-9694 ; 1687-9686
    ISSN (online) 1687-9694
    ISSN 1687-9686
    DOI 10.1155/2024/4123543
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  3. Article ; Online: Key Concerns and Drivers of Low-Cost Air Quality Sensor Use

    Priyanka Nadia deSouza

    Sustainability, Vol 14, Iss 584, p

    2022  Volume 584

    Abstract: Low-cost sensors are revolutionizing air pollution monitoring by providing real-time, highly localized air quality information. The relatively low-cost nature of these devices has made them accessible to the broader public. Although there have been ... ...

    Abstract Low-cost sensors are revolutionizing air pollution monitoring by providing real-time, highly localized air quality information. The relatively low-cost nature of these devices has made them accessible to the broader public. Although there have been several fitness-of-purpose appraisals of the various sensors on the market, little is known about what drives sensor usage and how the public interpret the data from their sensors. This article attempts to answer these questions by analyzing the key themes discussed in the user reviews of low-cost sensors on Amazon. The themes and use cases identified have the potential to spur interventions to support communities of sensor users and inform the development of actionable data-visualization strategies with the measurements from such instruments, as well as drive appropriate ‘fitness-of-purpose’ appraisals of such devices.
    Keywords low-cost air quality monitors ; citizen science ; Amazon reviews ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 333
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Nitroaromatics as hypoxic cell radiosensitizers

    Priyanka De / Kunal Roy

    European Journal of Medicinal Chemistry Reports, Vol 4, Iss , Pp 100035- (2022)

    A 2D-QSAR approach to explore structural features contributing to radiosensitization effectiveness

    2022  

    Abstract: Hypoxia is the prime component of tumor microenvironment that plays a pivotal role in cancer progression. Nitroaromatic compounds are known to enhance the sensitivity of hypoxic cells to ionizing radiation. The application of computational tools like ... ...

    Abstract Hypoxia is the prime component of tumor microenvironment that plays a pivotal role in cancer progression. Nitroaromatic compounds are known to enhance the sensitivity of hypoxic cells to ionizing radiation. The application of computational tools like Quantitative Structure-Activity Relationship (QSAR) can be used to predict newly developed nitroaromatics or compounds with missing data. In the present work, three datasets consisting of 18 nitrofurans, 11 nitrothiophenes and 84 nitroimidazoles were utilised for two-dimensional QSAR modeling to retrieve their structural features essential to elicit radiosensitivity. The work comprises two parts: (i) local modeling using individual datasets; and (ii) global modeling by clubbing the three datasets. The two-dimensional descriptors were calculated using Dragon (version 7.0) software. The developed models were obtained using various feature selection techniques applied in “Small Dataset Modeling” and “Double Cross Validation” tools available from https://dtclab.webs.com/software-tools. Finally, the models were validated using stringent metrics following the Organisation for Economic Co-operation and Development (OECD) guidelines. The developed models are robust, predictive, and are useful tools to predict the radiosensitization of newly developed nitroaromatics. Furthermore, the global model was used to predict two external sets comprising 10 and 47 compounds, and the prediction ability was validated using the “Prediction Reliability Indicator” tool.
    Keywords Hypoxia ; Nitroaromatics ; Radiosensitization ; Radiosentization effectiveness ; QSAR ; Pharmacy and materia medica ; RS1-441 ; Other systems of medicine ; RZ201-999
    Subject code 540
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Editorial: Gene Regulation Explored by Systems Biology in Livestock Science.

    Banerjee, Priyanka / Cesar, Aline Silva Mello / Lima, Andressa Oliveira De

    Frontiers in genetics

    2022  Volume 13, Page(s) 859061

    Language English
    Publishing date 2022-04-08
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.859061
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  6. Article ; Online: Lessons for the clinical nephrologist: an unusual cause of isolated proteinuria in a child with Familial Mediterranean Fever.

    Vanden Eynde, Nathalie / Koshy, Priyanka / De Somer, Lien / Knops, Noël

    Journal of nephrology

    2023  Volume 36, Issue 6, Page(s) 1699–1702

    MeSH term(s) Humans ; Child ; Familial Mediterranean Fever/complications ; Familial Mediterranean Fever/diagnosis ; Familial Mediterranean Fever/drug therapy ; Nephrologists ; Proteinuria/etiology ; Proteinuria/complications ; Amyloidosis
    Language English
    Publishing date 2023-04-10
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1120-3625 ; 1121-8428
    ISSN (online) 1724-6059
    ISSN 1120-3625 ; 1121-8428
    DOI 10.1007/s40620-023-01619-7
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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: Auditory chaos classification in real-world environments

    Priyanka Khante / Edison Thomaz / Kaya de Barbaro

    Frontiers in Digital Health, Vol

    2023  Volume 5

    Abstract: Background & motivationHousehold chaos is an established risk factor for child development. However, current methods for measuring household chaos rely on parent surveys, meaning existing research efforts cannot disentangle potentially dynamic ... ...

    Abstract Background & motivationHousehold chaos is an established risk factor for child development. However, current methods for measuring household chaos rely on parent surveys, meaning existing research efforts cannot disentangle potentially dynamic bidirectional relations between high chaos environments and child behavior problems.Proposed approachWe train and make publicly available a classifier to provide objective, high-resolution predictions of household chaos from real-world child-worn audio recordings. To do so, we collect and annotate a novel dataset of ground-truth auditory chaos labels compiled from over 411 h of daylong recordings collected via audio recorders worn by N=22 infants in their homes. We leverage an existing sound event classifier to identify candidate high chaos segments, increasing annotation efficiency 8.32× relative to random sampling.ResultOur best-performing model successfully classifies four levels of real-world household auditory chaos with a macro F1 score of 0.701 (Precision: 0.705, Recall: 0.702) and a weighted F1 score of 0.679 (Precision: 0.685, Recall: 0.680).SignificanceIn future work, high-resolution objective chaos predictions from our model can be leveraged for basic science and intervention, including testing theorized mechanisms by which chaos affects children’s cognition and behavior. Additionally, to facilitate further model development we make publicly available the first and largest balanced annotated audio dataset of real-world household chaos.
    Keywords auditory classification ; deep learning ; household chaos ; real-world dataset ; developmental psychology ; Medicine ; R ; Public aspects of medicine ; RA1-1270 ; Electronic computers. Computer science ; QA75.5-76.95
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Efficacy of the insect growth regulator novaluron in the control of dengue vector mosquitoes Aedes aegypti and Ae. albopictus.

    Herath, J M Manel K / De Silva, W A Priyanka P / Weeraratne, Thilini C / Karunaratne, S H P Parakrama

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 1988

    Abstract: Insect Growth Regulator (IGR) novaluron is an alternative to synthetic neuro-inhibitory insecticides. Present study was designed to assess appropriate dosages of novaluron for dengue vector control. Larvae of Aedes aegypti and Ae. albopictus were exposed ...

    Abstract Insect Growth Regulator (IGR) novaluron is an alternative to synthetic neuro-inhibitory insecticides. Present study was designed to assess appropriate dosages of novaluron for dengue vector control. Larvae of Aedes aegypti and Ae. albopictus were exposed to a concentration series of novaluron (Rimon EC10) for two fixed exposure periods of 7-days and 14-days to determined LC
    MeSH term(s) Animals ; Aedes ; Mosquito Vectors ; Juvenile Hormones ; Larva ; Dengue ; Phenylurea Compounds
    Chemical Substances novaluron (Z8H1B3CW0B) ; Juvenile Hormones ; Phenylurea Compounds
    Language English
    Publishing date 2024-01-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-52384-x
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  9. Article ; Online: Auditory chaos classification in real-world environments.

    Khante, Priyanka / Thomaz, Edison / de Barbaro, Kaya

    Frontiers in digital health

    2023  Volume 5, Page(s) 1261057

    Abstract: Background & motivation: Household chaos is an established risk factor for child development. However, current methods for measuring household chaos rely on parent surveys, meaning existing research efforts cannot disentangle potentially dynamic ... ...

    Abstract Background & motivation: Household chaos is an established risk factor for child development. However, current methods for measuring household chaos rely on parent surveys, meaning existing research efforts cannot disentangle potentially dynamic bidirectional relations between high chaos environments and child behavior problems.
    Proposed approach: We train and make publicly available a classifier to provide objective, high-resolution predictions of household chaos from real-world child-worn audio recordings. To do so, we collect and annotate a novel dataset of ground-truth auditory chaos labels compiled from over 411 h of daylong recordings collected via audio recorders worn by
    Result: Our best-performing model successfully classifies four levels of real-world household auditory chaos with a macro F1 score of 0.701 (Precision: 0.705, Recall: 0.702) and a weighted F1 score of 0.679 (Precision: 0.685, Recall: 0.680).
    Significance: In future work, high-resolution objective chaos predictions from our model can be leveraged for basic science and intervention, including testing theorized mechanisms by which chaos affects children's cognition and behavior. Additionally, to facilitate further model development we make publicly available the first and largest balanced annotated audio dataset of real-world household chaos.
    Language English
    Publishing date 2023-12-21
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-253X
    ISSN (online) 2673-253X
    DOI 10.3389/fdgth.2023.1261057
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  10. Article ; Online: Maternal contingent responses to distress facilitate infant soothing but not in mothers with depression or infants high in negative affect.

    de Barbaro, Kaya / Khante, Priyanka / Maier, Meeka / Goodman, Sherryl

    Developmental psychology

    2023  Volume 60, Issue 2, Page(s) 294–305

    Abstract: Depression in mothers is consistently associated with reduced caregiving sensitivity and greater infant negative affect expression. The current article examined the real-time behavioral mechanisms underlying these associations using Granger causality ... ...

    Abstract Depression in mothers is consistently associated with reduced caregiving sensitivity and greater infant negative affect expression. The current article examined the real-time behavioral mechanisms underlying these associations using Granger causality time series analyses in a sample of mothers (
    MeSH term(s) Infant ; Humans ; Female ; Male ; Maternal Behavior/physiology ; Mother-Child Relations ; Depression ; Mothers
    Language English
    Publishing date 2023-11-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2066223-3
    ISSN 1939-0599 ; 0012-1649
    ISSN (online) 1939-0599
    ISSN 0012-1649
    DOI 10.1037/dev0001607
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