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  1. Article ; Online: Evolutionary and ecological correlates of thiaminase in fishes.

    Rowland, Freya E / Richter, Catherine A / Tillitt, Donald E / Walters, David M

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 18147

    Abstract: Thiamine (vitamin ... ...

    Abstract Thiamine (vitamin B
    MeSH term(s) Humans ; Animals ; Thiamine/metabolism ; Fishes/metabolism ; Thiamine Deficiency ; Hydrolases/metabolism ; Salmonidae/metabolism
    Chemical Substances thiaminase II (EC 3.5.99.2) ; Thiamine (X66NSO3N35) ; Hydrolases (EC 3.-)
    Language English
    Publishing date 2023-10-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-44654-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Genetic basis of thiaminase I activity in a vertebrate, zebrafish Danio rerio.

    Richter, Catherine A / Evans, Allison N / Heppell, Scott A / Zajicek, James L / Tillitt, Donald E

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 698

    Abstract: Thiamine (vitamin ... ...

    Abstract Thiamine (vitamin B
    MeSH term(s) Animals ; Thiamine ; Thiamine Deficiency ; Zebrafish/genetics ; Alkyl and Aryl Transferases/genetics
    Chemical Substances thiamin pyridinylase (EC 2.5.1.2) ; Thiamine (X66NSO3N35) ; Alkyl and Aryl Transferases (EC 2.5.-)
    Language English
    Publishing date 2023-01-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-27612-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Declines in Reproductive Condition of Male Largemouth Bass (

    Leet, Jessica K / Richter, Catherine A / Gale, Robert W / Tillitt, Donald E / Jenkins, Jill A

    International journal of molecular sciences

    2022  Volume 23, Issue 24

    Abstract: Reproductive abnormalities, that could lead to possible effects at the population level, have been observed in wild fish throughout the United States, with high prevalence in largemouth bass (LMB; ...

    Abstract Reproductive abnormalities, that could lead to possible effects at the population level, have been observed in wild fish throughout the United States, with high prevalence in largemouth bass (LMB;
    Language English
    Publishing date 2022-12-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms232416131
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  4. Article ; Online: Change in blood test results prior to diagnosis in multiple myeloma.

    Atkin, Catherine / Sapey, Elizabeth / Richter, Alex

    Clinical medicine (London, England)

    2020  Volume 20, Issue Suppl 2, Page(s) s99–s100

    MeSH term(s) Hematologic Tests ; Humans ; Multiple Myeloma/diagnosis
    Language English
    Publishing date 2020-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmed.20-2-s99
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5439: Show issues Location:
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  5. Article ; Online: Evolutionary and ecological correlates of thiaminase in fishes

    Freya E. Rowland / Catherine A. Richter / Donald E. Tillitt / David M. Walters

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    2023  Volume 9

    Abstract: Abstract Thiamine (vitamin B1) is required by all living organisms in multiple metabolic pathways. It is scarce in natural systems, and deficiency can lead to reproductive failure, neurological issues, and death. One major cause of thiamine deficiency is ...

    Abstract Abstract Thiamine (vitamin B1) is required by all living organisms in multiple metabolic pathways. It is scarce in natural systems, and deficiency can lead to reproductive failure, neurological issues, and death. One major cause of thiamine deficiency is an overreliance on diet items containing the enzyme thiaminase. Thiaminase activity has been noted in many prey fishes and linked to cohort failure in salmonid predators that eat prey fish with thiaminase activity, yet it is generally unknown whether evolutionary history, fish traits, and/or environmental conditions lead to production of thiaminase. We conducted literature and GenBank BLAST sequence searches to collect thiaminase activity data and sequence homology data in expressed protein sequences for 300 freshwater and marine fishes. We then tested whether presence or absence of thiaminase could be predicted by evolutionary relationships, trophic level, omega-3 fatty acid concentrations, habitat, climate, invasive potential, and body size. There was no evolutionary relationship with thiaminase activity. It first appears in Class Actinoptergyii (bony ray-finned fishes) and is present across the entire Actinoptergyii phylogeny in both primitive and derived fish orders. Instead, ecological factors explained the most variation in thiaminase: fishes were more likely to express thiaminase if they fed closer to the base of the food web, were high in polyunsaturated fatty acids, lived in freshwater, and were from tropical climates. These data provide a foundation for understanding sources of thiaminase leading to thiamine deficiency in fisheries and other organisms, including humans that eat uncooked fish.
    Keywords Medicine ; R ; Science ; Q
    Subject code 333 ; 590
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques.

    Jacob-Dolan, Catherine / Ty, Darren / Hope, David / McMahan, Katherine / Liu, Jinyan / Powers, Olivia C / Cotter, Catherine A / Sciacca, Michela / Wu, Cindy / Borducchi, Erica / Bouffard, Emily / Richter, Hannah / Velasco, Jason / Teow, Elyse / Boursiquot, Mona / Cook, Anthony / Feliciano, Karen / Yalley-Ogunro, Jake / Seaman, Michael S /
    Pessiant, Laurent / Lewis, Mark G / Andersen, Hanne / Moss, Bernard / Barouch, Dan H

    Science translational medicine

    2024  Volume 16, Issue 740, Page(s) eadl4317

    Abstract: The 2022-2023 mpox outbreak triggered vaccination efforts using smallpox vaccines that were approved for mpox, including modified vaccinia Ankara (MVA; JYNNEOS), which is a safer alternative to live replicating vaccinia virus (ACAM2000). Here, we compare ...

    Abstract The 2022-2023 mpox outbreak triggered vaccination efforts using smallpox vaccines that were approved for mpox, including modified vaccinia Ankara (MVA; JYNNEOS), which is a safer alternative to live replicating vaccinia virus (ACAM2000). Here, we compare the immunogenicity and protective efficacy of JYNNEOS by the subcutaneous or intradermal routes, ACAM2000 by the percutaneous route, and subunit Ad35 vector-based L1R/B5R or L1R/B5R/A27L/A33R vaccines by the intramuscular route in rhesus macaques. All vaccines provided robust protection against high-dose intravenous mpox virus challenge with the current outbreak strain, with ACAM2000 providing near complete protection and JYNNEOS and Ad35 vaccines providing robust but incomplete protection. Protection correlated with neutralizing antibody responses as well as L1R/M1R- and B5R/B6R-specific binding antibody responses, although additional immune responses likely also contributed to protection. This study demonstrates the protective efficacy of multiple vaccine platforms against mpox virus challenge, including both current clinical vaccines and vectored subunit vaccines.
    MeSH term(s) Animals ; Vaccinia virus/genetics ; Macaca mulatta ; Mpox (monkeypox) ; Antibodies, Viral ; Smallpox Vaccine ; Vaccines, Subunit
    Chemical Substances ACAM2000 ; Antibodies, Viral ; Smallpox Vaccine ; Vaccines, Subunit
    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2518854-9
    ISSN 1946-6242 ; 1946-6234
    ISSN (online) 1946-6242
    ISSN 1946-6234
    DOI 10.1126/scitranslmed.adl4317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6941: Show issues Location:
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  7. Article ; Online: Grass Carp Reproduction in Small Tributaries of Harry S. Truman Reservoir, Missouri: Implications for Establishment in Novel Habitats

    Hayer, Cari‐Ann / Bayless, Michael A. / Richter, Catherine A. / George, Amy E. / Chapman, Duane C.

    North American Journal of Fisheries Management. 2023 Feb., v. 43, no. 1 p.154-163

    2023  

    Abstract: Substantial work has been conducted to estimate the river length required for recruitment of invasive Grass Carp Ctenopharyngodon idella and bigheaded carps (Bighead Carp Hypophthalmichthys nobilis and Silver Carp H. molitrix); however, the distance ... ...

    Abstract Substantial work has been conducted to estimate the river length required for recruitment of invasive Grass Carp Ctenopharyngodon idella and bigheaded carps (Bighead Carp Hypophthalmichthys nobilis and Silver Carp H. molitrix); however, the distance upstream and size of stream required for spawning remain unclear. Adult Grass Carp are regularly captured in Harry S. Truman Reservoir, Missouri, although there have been only unconfirmed sightings of Silver Carp. Fertile diploid Grass Carp are used legally for vegetation control in Missouri; however, it is uncertain whether Grass Carp in Harry S. Truman Reservoir are the result of natural reproduction or escapees. We used ichthyoplankton tows and environmental DNA (eDNA) to investigate which carp species were present in the reservoir basin and to determine whether these carps were spawning in reservoir tributaries. Grass Carp eggs were collected in four of five tributaries during June 2014. We did not detect eggs, larvae, or eDNA of Bighead Carp or Silver Carp. The occurrence of Grass Carp eggs generally coincided with rapid increases in discharge and turbidity. These tributaries may be the smallest rivers worldwide in which spawning of Grass Carp has been documented. We infer from the developmental stages captured and the distance from the reservoir that sufficient river length exists for egg survival. These results have broad implications concerning the establishment of Grass Carp in other novel habitats, including other reservoirs and lake basins, smaller rivers, and the Laurentian Great Lakes ecosystem.
    Keywords Ctenopharyngodon idella ; Hypophthalmichthys molitrix ; Hypophthalmichthys nobilis ; administrative management ; adults ; basins ; carp ; diploidy ; ecosystems ; eggs ; environmental DNA ; ichthyoplankton ; invasive species ; lakes ; reproduction ; rivers ; streams ; turbidity ; vegetation ; Missouri
    Language English
    Dates of publication 2023-02
    Size p. 154-163.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 779391-1
    ISSN 0275-5947
    ISSN 0275-5947
    DOI 10.1002/nafm.10670
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 4271: Show issues

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  8. Article ; Online: The life cycle of

    Boshoff, Willem H P / Wood, Alan R / Visser, Botma / Bender, Cornel M / Joubert, Lize / Richter, Jan / Aime, M Catherine / Pretorius, Zacharias A

    Mycologia

    2022  Volume 114, Issue 2, Page(s) 319–336

    Abstract: Rust fungi are important plant pathogens and have been extensively studied on crops and other host plants worldwide. This study describes the heterecious life cycle of a rust fungus ... ...

    Abstract Rust fungi are important plant pathogens and have been extensively studied on crops and other host plants worldwide. This study describes the heterecious life cycle of a rust fungus on
    MeSH term(s) Animals ; Basidiomycota ; Digitaria ; Life Cycle Stages ; Phylogeny ; Plant Diseases/microbiology ; Plants ; Puccinia ; Solanum ; South Africa
    Language English
    Publishing date 2022-04-01
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 281335-x
    ISSN 1557-2536 ; 0027-5514
    ISSN (online) 1557-2536
    ISSN 0027-5514
    DOI 10.1080/00275514.2022.2031493
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1291: Show issues Location:
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  9. Article ; Online: Toward invasive mussel genetic biocontrol: Approaches, challenges, and perspectives.

    Hernández Elizárraga, Víctor H / Ballantyne, Scott / O'Brien, Lindsey G / Americo, Juliana A / Suhr, Steven T / Senut, Marie-Claude / Minerich, Ben / Merkes, Christopher M / Edwards, Thea M / Klymus, Katy / Richter, Catherine A / Waller, Diane L / Passamaneck, Yale J / Rebelo, Mauro F / Gohl, Daryl M

    iScience

    2023  Volume 26, Issue 10, Page(s) 108027

    Abstract: Invasive freshwater mussels, such as the zebra ( ...

    Abstract Invasive freshwater mussels, such as the zebra (
    Language English
    Publishing date 2023-09-28
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2023.108027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Genetic duplication of tissue factor reveals subfunctionalization in venous and arterial hemostasis.

    Grzegorski, Steven J / Zhao, Yakun / Richter, Catherine E / Ku, Chia-Jui / Lavik, Kari I / Paul, Divyani / Morrissey, James H / Shavit, Jordan A

    PLoS genetics

    2022  Volume 18, Issue 11, Page(s) e1010534

    Abstract: Tissue factor (TF) is an evolutionarily conserved protein necessary for initiation of hemostasis. Zebrafish have two copies of the tissue factor gene (f3a and f3b) as the result of an ancestral teleost fish duplication event (so called ohnologs). In vivo ...

    Abstract Tissue factor (TF) is an evolutionarily conserved protein necessary for initiation of hemostasis. Zebrafish have two copies of the tissue factor gene (f3a and f3b) as the result of an ancestral teleost fish duplication event (so called ohnologs). In vivo physiologic studies of TF function have been difficult given early lethality of TF knockout in the mouse. We used genome editing to produce knockouts of both f3a and f3b in zebrafish. Since ohnologs arose through sub- or neofunctionalization, they can unmask unknown functions of non-teleost genes and could reveal whether mammalian TF has developmental functions distinct from coagulation. Here we show that a single copy of either f3a or f3b is necessary and sufficient for normal lifespan. Complete loss of TF results in lethal hemorrhage by 2-4 months despite normal embryonic and vascular development. Larval vascular endothelial injury reveals predominant roles for TFa in venous circulation and TFb in arterial circulation. Finally, we demonstrate that loss of TF predisposes to a stress-induced cardiac tamponade independent of its role in fibrin formation. Overall, our data suggest partial subfunctionalization of TFa and TFb. This multigenic zebrafish model has the potential to facilitate study of the role of TF in different vascular beds.
    MeSH term(s) Animals ; Mice ; Gene Duplication ; Larva ; Thromboplastin/genetics ; Thromboplastin/physiology ; Zebrafish/genetics ; Zebrafish/metabolism ; Zebrafish Proteins/genetics ; Hemostasis/genetics ; Veins/physiology ; Arteries/physiology
    Chemical Substances Thromboplastin (9035-58-9) ; Zebrafish Proteins
    Language English
    Publishing date 2022-11-30
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2186725-2
    ISSN 1553-7404 ; 1553-7390
    ISSN (online) 1553-7404
    ISSN 1553-7390
    DOI 10.1371/journal.pgen.1010534
    Database MEDical Literature Analysis and Retrieval System OnLINE

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