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  1. Article: Innovative Techniques for Infection Control and Surveillance in Hospital Settings and Long-Term Care Facilities: A Scoping Review.

    Arzilli, Guglielmo / De Vita, Erica / Pasquale, Milena / Carloni, Luca Marcello / Pellegrini, Marzia / Di Giacomo, Martina / Esposito, Enrica / Porretta, Andrea Davide / Rizzo, Caterina

    Antibiotics (Basel, Switzerland)

    2024  Volume 13, Issue 1

    Abstract: Healthcare-associated infections (HAIs) pose significant challenges in healthcare systems, with preventable surveillance playing a crucial role. Traditional surveillance, although effective, is resource-intensive. The development of new technologies, ... ...

    Abstract Healthcare-associated infections (HAIs) pose significant challenges in healthcare systems, with preventable surveillance playing a crucial role. Traditional surveillance, although effective, is resource-intensive. The development of new technologies, such as artificial intelligence (AI), can support traditional surveillance in analysing an increasing amount of health data or meeting patient needs. We conducted a scoping review, following the PRISMA-ScR guideline, searching for studies of new digital technologies applied to the surveillance, control, and prevention of HAIs in hospitals and LTCFs published from 2018 to 4 November 2023. The literature search yielded 1292 articles. After title/abstract screening and full-text screening, 43 articles were included. The mean study duration was 43.7 months. Surgical site infections (SSIs) were the most-investigated HAI and machine learning was the most-applied technology. Three main themes emerged from the thematic analysis: patient empowerment, workload reduction and cost reduction, and improved sensitivity and personalization. Comparative analysis between new technologies and traditional methods showed different population types, with machine learning methods examining larger populations for AI algorithm training. While digital tools show promise in HAI surveillance, especially for SSIs, challenges persist in resource distribution and interdisciplinary integration in healthcare settings, highlighting the need for ongoing development and implementation strategies.
    Language English
    Publishing date 2024-01-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics13010077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Investigating Resistance to Carbapenems in Enterobacterales: A Descriptive Epidemiological Study of 2021 Screening in an Italian Teaching Hospital.

    De Vita, Erica / De Angelis, Luigi / Arzilli, Guglielmo / Baglivo, Francesco / Barnini, Simona / Vecchione, Alessandra / Baggiani, Angelo / Rizzo, Caterina / Porretta, Andrea Davide / Teams Aid

    Pathogens (Basel, Switzerland)

    2023  Volume 12, Issue 9

    Abstract: Antimicrobial resistance (AMR) presents a growing threat to global healthcare. This descriptive epidemiological study investigates the prevalence and characteristics of Enterobacterales with AMR factors in a tertiary teaching hospital in Italy over the ... ...

    Abstract Antimicrobial resistance (AMR) presents a growing threat to global healthcare. This descriptive epidemiological study investigates the prevalence and characteristics of Enterobacterales with AMR factors in a tertiary teaching hospital in Italy over the course of the year 2021. In 2021, the prevalence of colonisation by Enterobacterales with AMR factors in patients was 1.08%. During the observation period, a total of 8834 rectal swabs were performed, with 1453 testing positive. A total of 5639 rectal swabs were performed according to a hospital procedure for the active screening of MDRO colonisation at the time of admission. Of these, 679 were positive for microorganisms under surveillance, and 74 patients were colonised with Enterobacterales, predominantly
    Language English
    Publishing date 2023-09-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12091140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Assessing vaccine hesitancy and health literacy using a new Italian vaccine confidence index and a modified Italian medical term recognition test: A cross-sectional survey on Italian parents.

    Arzilli, Guglielmo / Stacchini, Lorenzo / Casigliani, Virginia / Mazzilli, Sara / Aquino, Francesco / Oradini-Alacreu, Aurea / Bruni, Beatrice / Quattrone, Filippo / Papini, Francesca / Sironi, Daniele / Porretta, Andrea Davide / Privitera, Gaetano Pierpaolo / Rizzo, Caterina / Tavoschi, Lara / Lopalco, Pier Luigi

    Human vaccines & immunotherapeutics

    2023  Volume 19, Issue 3, Page(s) 2271765

    Abstract: The decline in children's vaccination coverage and the resurgence of preventable infectious diseases draw attention to parents' vaccine hesitancy. Our study introduces two validated tools to independently assess vaccine hesitancy and health literacy ... ...

    Abstract The decline in children's vaccination coverage and the resurgence of preventable infectious diseases draw attention to parents' vaccine hesitancy. Our study introduces two validated tools to independently assess vaccine hesitancy and health literacy among parents with school-age children. We developed a Vaccine Confidence Index (VCI) from 10 Likert items, exploring their relationships through exploratory and confirmatory factor analyses. We modified the IMETER (Italian medical term recognition test) to measure health literacy. We assessed the internal consistency of the modified IMETER and the 10 Likert items using Cronbach's alpha test (α) and McDonald's omega total coefficient (ω) with good results (ω = 0.92, α = 0.90; ω = 0.87, α = 0.82 respectively). We used these tools within a questionnaire conducted on 743 parents recruited from pediatric clinic waiting rooms in Italy, collecting demographic data, information sources on vaccines and vaccine-preventable diseases knowledge. The VCI resulting from factor analyses consisted of six items on a ten-point Likert scale, reflecting the ratio of positive to negative items. The survey revealed significant variations in the VCI according to individual features such as education, use of social networks, or Health institutions as sources of information. Multivariate logistic regression identified an association between vaccine intention and the VCI. Health literacy was functional for 91.2% of participants, but knowledge about vaccine-preventable diseases was generally low. The VCI showed no significant association with health literacy and vaccine-preventable diseases knowledge. The VCI and the modified IMETER effectively assess vaccination attitude and health literacy, offering valuable public health tools for tailoring vaccination campaigns to hesitant population subgroups.
    MeSH term(s) Child ; Humans ; Cross-Sectional Studies ; Health Literacy ; Vaccination Hesitancy ; Vaccine-Preventable Diseases ; Vaccines ; Italy ; Parents
    Chemical Substances Vaccines
    Language English
    Publishing date 2023-10-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2023.2271765
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy

    Porretta, Andrea Davide / Baggiani, Angelo / Arzilli, Guglielmo / Casigliani, Virginia / Mariotti, Tommaso / Mariottini, Francesco / Scardina, Giuditta / Sironi, Daniele / Totaro, Michele / Barnini, Simona / Privitera, Gaetano Pierpaolo

    Pathogens. 2020 Aug. 05, v. 9, no. 8

    2020  

    Abstract: We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital. These patients had an increased risk of ... ...

    Abstract We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital. These patients had an increased risk of NDM-CRE acquisition versus the usual patients (75.9 vs. 25.3 cases/10,000 patient days). The co-infection significantly increased the duration of hospital stay (32.9 vs. 15.8 days).
    Keywords Coronavirus infections ; duration ; epidemiology ; hospitals ; mixed infection ; pathogens ; patients ; risk ; India ; Italy
    Language English
    Dates of publication 2020-0805
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    Note NAL-light
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens9080635
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Screening for antimicrobial-resistant Gram-negative bacteria in hospitalised patients, and risk of progression from colonisation to infection: Systematic review.

    Arzilli, Guglielmo / Scardina, Giuditta / Casigliani, Virginia / Petri, Davide / Porretta, Andrea / Moi, Marco / Lucenteforte, Ersilia / Rello, Jordi / Lopalco, Pierluigi / Baggiani, Angelo / Privitera, Gaetano Pierpaolo / Tavoschi, Lara

    The Journal of infection

    2021  Volume 84, Issue 2, Page(s) 119–130

    Abstract: Background: Transmission of antimicrobial-resistant Gram-negative bacteria (AMR-GNB) amongst hospitalised patients can lead to new cases of carriage, infection and outbreaks, hence the need for early carrier identification. We aim to explore two key ... ...

    Abstract Background: Transmission of antimicrobial-resistant Gram-negative bacteria (AMR-GNB) amongst hospitalised patients can lead to new cases of carriage, infection and outbreaks, hence the need for early carrier identification. We aim to explore two key elements that may guide control policies for colonisation/infection in hospital settings: screening practices on admission to hospital wards and risk of developing infection from colonisation.
    Methods: We searched on PubMed, Scopus and Cochrane databases for studies published from 2010 up to 2021 reporting on adult patients hospitalised in high-income countries.
    Results: The search retrieved 11,853 articles. After screening, 100 studies were included. Combining target patient groups and setting type, we identified six screening approaches. The most reported approach was all admitted patients to high-risk (HR) wards (49.4%). The overall prevalence of AMR-GNB was 13.8% (95%CI 9.3-19.0) with significant differences across regions and time. Risk of progression to infection amongst colonised patients was 11.0% (95%CI 8.0-14.3) and varied according to setting and pathogens' group (p value<0.0001), with higher values reported for Klebsiella species (18.1%; 95%CI 8.9-29.3).
    Conclusions: While providing a comprehensive overview of the screening approaches, our study underlines the considerable burden of AMR-GNB colonisation and risk of progression to infection in hospitals by pathogen, setting and time.
    MeSH term(s) Adult ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Bacteria ; Cross Infection/microbiology ; Gram-Negative Bacteria ; Gram-Negative Bacterial Infections/microbiology ; Humans
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-11-15
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2021.11.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy.

    Porretta, Andrea Davide / Baggiani, Angelo / Arzilli, Guglielmo / Casigliani, Virginia / Mariotti, Tommaso / Mariottini, Francesco / Scardina, Giuditta / Sironi, Daniele / Totaro, Michele / Barnini, Simona / Privitera, Gaetano Pierpaolo

    Pathogens (Basel, Switzerland)

    2020  Volume 9, Issue 8

    Abstract: We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital. These patients had an increased risk of ... ...

    Abstract We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital. These patients had an increased risk of NDM-CRE acquisition versus the usual patients (75.9 vs. 25.3 cases/10,000 patient days). The co-infection significantly increased the duration of hospital stay (32.9 vs. 15.8 days).
    Keywords covid19
    Language English
    Publishing date 2020-08-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens9080635
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy

    Andrea Davide Porretta / Angelo Baggiani / Guglielmo Arzilli / Virginia Casigliani / Tommaso Mariotti / Francesco Mariottini / Giuditta Scardina / Daniele Sironi / Michele Totaro / Simona Barnini / Gaetano Pierpaolo Privitera

    Pathogens, Vol 9, Iss 635, p

    2020  Volume 635

    Abstract: We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital. These patients had an increased risk of ... ...

    Abstract We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital. These patients had an increased risk of NDM-CRE acquisition versus the usual patients (75.9 vs. 25.3 cases/10,000 patient days). The co-infection significantly increased the duration of hospital stay (32.9 vs. 15.8 days).
    Keywords COVID-19 ; health care related infections ; surveillance ; New Delhi metallo-beta-lactamase ; Medicine ; R ; covid19
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy

    Porretta, Andrea Davide / Baggiani, Angelo / Arzilli, Guglielmo / Casigliani, Virginia / Mariotti, Tommaso / Mariottini, Francesco / Scardina, Giuditta / Sironi, Daniele / Totaro, Michele / Barnini, Simona / Privitera, Gaetano Pierpaolo

    Abstract: We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital. These patients had an increased risk of ... ...

    Abstract We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital. These patients had an increased risk of NDM-CRE acquisition versus the usual patients (75.9 vs. 25.3 cases/10,000 patient days). The co-infection significantly increased the duration of hospital stay (32.9 vs. 15.8 days).
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32764228
    Database COVID19

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