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  1. Article ; Online: Comparison of sulfur ointment and permethrin treatments in scabies.

    Ertugrul, Goksen / Aktas, Habibullah

    Dermatologic therapy

    2022  Volume 35, Issue 12, Page(s) e15897

    Abstract: Scabies is a contagious, parasitic skin disease that adversely affects the quality of life and, can cause systemic complications if it is not properly treated. Sulfur ointment and permethrin cream are among the most used topical agents in the treatment ... ...

    Abstract Scabies is a contagious, parasitic skin disease that adversely affects the quality of life and, can cause systemic complications if it is not properly treated. Sulfur ointment and permethrin cream are among the most used topical agents in the treatment of scabies. In this study, we aimed to compare the efficacy of sulfur ointment and permethrin cream in the treatment of scabies. In this single-center study, patients who were diagnosed with scabies in the dermatology outpatient clinics of Karabuk University Training and Research Hospital between April, 2021 and September, 2021 were investigated retrospectively. Age, gender, date of diagnosis, topical agent used for scabies treatment, and response to the treatment at the control examination in the second week were recorded. The patients were divided into two groups those receiving 5% permethrin cream or 10% sulfur ointment, and the treatment efficacy of both agents was compared. This study showed that 10% sulfur ointment was significantly more effective in treating scabies than 5% permethrin cream (p < 0.001). Moreover, younger patients with scabies responded better to both treatments. 10% Sulfur ointment can be considered a safe and effective topical option in the treatment of scabies. The resistance to 5% permethrin cream, which is the most commonly used agent for scabies, can be a concern as an unexpected low success rate was obtained in this study.
    MeSH term(s) Humans ; Permethrin/adverse effects ; Scabies/diagnosis ; Scabies/drug therapy ; Ointments ; Quality of Life ; Retrospective Studies ; Sulfur/adverse effects ; Insecticides ; Ivermectin
    Chemical Substances Permethrin (509F88P9SZ) ; Ointments ; Sulfur (70FD1KFU70) ; Insecticides ; Ivermectin (70288-86-7)
    Language English
    Publishing date 2022-10-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.15897
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5181: Show issues Location:
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  2. Article ; Online: Herpes zoster cases increased during COVID-19 outbreak. Is it possible a relation?

    Ertugrul, Goksen / Aktas, Habibullah

    The Journal of dermatological treatment

    2020  Volume 33, Issue 2, Page(s) 1180

    MeSH term(s) COVID-19 ; Disease Outbreaks ; Herpes Zoster/epidemiology ; Herpesvirus 3, Human ; Humans
    Keywords covid19
    Language English
    Publishing date 2020-07-07
    Publishing country England
    Document type Letter
    ZDB-ID 1036299-x
    ISSN 1471-1753 ; 0954-6634
    ISSN (online) 1471-1753
    ISSN 0954-6634
    DOI 10.1080/09546634.2020.1789040
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    Zs.A 2627: Show issues Location:
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  3. Article ; Online: Does obesity prevent occurrence of genital ulcers in women with Behçet's disease? A striking observation in 17 consecutive patients.

    Aktas, Habibullah / Ertugrul, Goksen

    International journal of dermatology

    2020  Volume 59, Issue 9, Page(s) e342–e343

    MeSH term(s) Behcet Syndrome/complications ; Behcet Syndrome/epidemiology ; Female ; Genitalia ; Humans ; Obesity/complications ; Obesity/epidemiology ; Oral Ulcer ; Ulcer
    Language English
    Publishing date 2020-06-09
    Publishing country England
    Document type Letter
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.14992
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  4. Article ; Online: Indirect skin sign of COVID-19 days: Striae rubrae.

    Ertugrul, Goksen / Aktas, Habibullah

    Journal of cosmetic dermatology

    2020  Volume 19, Issue 9, Page(s) 2161

    MeSH term(s) COVID-19/epidemiology ; Humans ; SARS-CoV-2 ; Sedentary Behavior ; Striae Distensae/epidemiology ; Turkey/epidemiology ; Weight Gain ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-07-24
    Publishing country England
    Document type Letter
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.13607
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    Zs.A 6539: Show issues Location:
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  5. Article ; Online: Lower Levels of Vitamin B12 Among Patients with Viral Warts Compared with Control Subjects

    Habibullah Aktaş / Gökşen Ertuğrul

    Düzce Tıp Fakültesi Dergisi, Vol 24, Iss 1, Pp 74-

    A Retrospective Study

    2022  Volume 77

    Abstract: Aim: Viral wart is a common benign infectious dermatosis. It remains unclear why not everyone exposed to HPV develops warts. It is known that vitamin and mineral deficiencies can affect impair natural and acquired immunity and lead to a tendency to get ... ...

    Abstract Aim: Viral wart is a common benign infectious dermatosis. It remains unclear why not everyone exposed to HPV develops warts. It is known that vitamin and mineral deficiencies can affect impair natural and acquired immunity and lead to a tendency to get more infections. This study aimed to determine the potential utility of evaluating vitamin B12, folic acid, and ferritin levels in patients with viral warts. Material and Methods: In this retrospective study, 70 patients who were diagnosed with viral warts in the dermatology outpatient clinic of Karabük University Training and Research Hospital between January 2018 and December 2019 were included. 70 healthy individuals matched with viral wart patients in terms of gender and age were included as the control group. Serum vitamin B12, folic acid, and ferritin levels of both groups were detected and compared from the hospital automation system. Results: Vitamin B12 level was detected statistically significantly lower in the viral wart group as compared to the control group (p=0.046). Although serum ferritin levels were found lower in the viral wart group, this difference was not statistically significant (p=0.677). No statistically significant difference was detected between the viral wart and control groups in terms of folate levels (p=0.879). Conclusion: In patients with viral warts with low serum vitamin B12 levels, replacement therapy could be considered. Also, the evaluation of serum ferritin level, an iron storage parameter in the body, is important in patients with viral warts infection.
    Keywords wart ; vitamin b12 ; folic acid ; ferritin ; viral warts ; siğil ; b12 vitamini ; folik asit ; viral siğil ; Medicine ; R ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Duzce University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: There is no evidence of cochlear and vestibular melanocyte damage in patients with alopecia areata.

    Ertugrul, Goksen / Ertugrul, Suha / Soylemez, Emre

    International journal of clinical practice

    2021  Volume 75, Issue 5, Page(s) e14040

    Abstract: Purpose: Follicular melanocytes are known to be damaged in alopecia areata (AA). However, it is not clear whether melanocytes are the primary target of autoimmunity and whether melanocytes in the inner ear are affected. This study aimed to detect ... ...

    Abstract Purpose: Follicular melanocytes are known to be damaged in alopecia areata (AA). However, it is not clear whether melanocytes are the primary target of autoimmunity and whether melanocytes in the inner ear are affected. This study aimed to detect possible cochlear and/or vestibular melanocyte damage in AA patients.
    Methods: Thirty-two AA patients and 35 sex- and age-matched healthy volunteers were evaluated between November 2018 and March 2020 at the Karabük University Training and Research Hospital. The conventional pure tone audiometry test and distortion product otoacoustic emission test were performed to evaluate hearing. To evaluate the vestibular function, the following tests were performed: the vestibulospinal reflex tests (Romberg test, tandem stance test and tandem walking test); positional balance tests (Dix-Hallpike test, supine roll test and head hanging test); vestibulo-ocular reflex tests (caloric test, head shake test) and oculomotor tests (saccade, smooth pursuit and optokinetic).
    Results: The mean age of AA patients was 31.94 ± 11.86 years (range, 15-67 years). There were no significant differences in the results of the hearing and balance tests between the groups. Furthermore, disease parameters (duration of the last attack, recurrence, positive family history, positive pull test, the severity of the disease, etc) were not associated with hearing loss and vestibular damage.
    Conclusion: AA patients did not exhibit hearing loss or balance abnormalities that would indicate cochlear and vestibular melanocyte damage. The lack of damage to the inner ear melanocytes in AA patients may indicate that follicular melanocytes are affected secondary to autoimmune damage in the hair bulb, and melanocytes are not the primary target in the pathogenesis of AA.
    MeSH term(s) Adolescent ; Adult ; Aged ; Alopecia Areata ; Humans ; Melanocytes ; Middle Aged ; Physical Examination ; Young Adult
    Language English
    Publishing date 2021-01-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1386246-7
    ISSN 1742-1241 ; 1368-5031
    ISSN (online) 1742-1241
    ISSN 1368-5031
    DOI 10.1111/ijcp.14040
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    Ua VI Zs.301: Show issues Location:
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  9. Article ; Online: Indirect skin sign of COVID‐19 days

    Ertugrul, Goksen / Aktas, Habibullah

    Journal of Cosmetic Dermatology

    Striae rubrae

    2020  Volume 19, Issue 9, Page(s) 2161–2161

    Keywords Dermatology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2280551-5
    ISSN 1473-2130
    ISSN 1473-2130
    DOI 10.1111/jocd.13607
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Evaluation of audiovestibular system in psoriasis patients without joint involvement.

    Ertugrul, Goksen / Ertugrul, Suha / Soylemez, Emre

    Dermatologic therapy

    2020  Volume 33, Issue 3, Page(s) e13396

    Abstract: Inner ear involvement may occur in systemic autoimmune diseases. Although there are studies evaluating hearing in psoriasis patients, its effect on the balance system is not clear. The aim of the present study was to evaluate the audiovestibular system ... ...

    Abstract Inner ear involvement may occur in systemic autoimmune diseases. Although there are studies evaluating hearing in psoriasis patients, its effect on the balance system is not clear. The aim of the present study was to evaluate the audiovestibular system in psoriasis patients without joint involvement. In this prospective study, the audiovestibular system of 32 psoriasis patients without joint involvement and 35 healthy volunteers were evaluated. The severity of the disease was determined by the psoriasis area severity index (PASI). There was no significant difference between the groups in terms of hearing test results, while the abnormal caloric test response was significantly higher in the psoriatic patients. PASI scores of psoriasis patients with abnormal caloric test results were higher than those with normal caloric test response. In psoriasis patients without joint involvement, the hearing was not affected, but the vestibular system was. The severity of the disease was associated with vestibular involvement. Particularly in patients with severe psoriasis, it must be considered that the vestibular system might be affected, and vestibular evaluations should be performed.
    MeSH term(s) Humans ; Prospective Studies ; Psoriasis/diagnosis ; Severity of Illness Index
    Language English
    Publishing date 2020-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.13396
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    In stock of ZB MED Cologne/Königswinter

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