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Article ; Online: Indoor air quality and COVID-19.

Abouleish, M Y Z

2020 Volume 191, Page(s) 1–2

MeSH term(s)	Air Pollution, Indoor ; COVID-19 ; Humans ; SARS-CoV-2
Language	English
Publishing date	2020-05-07
Publishing country	Netherlands
Document type	Letter ; Comment
ZDB-ID	427333-3
ISSN	1476-5616 ; 0033-3506
ISSN (online)	1476-5616
ISSN	0033-3506
DOI	10.1016/j.puhe.2020.04.047
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Article ; Online: COVID-19 Vaccination and Healthcare Demand.

Betti, Matthew I / Abouleish, Amira Hassan / Spofford, Victoria / Peddigrew, Cory / Diener, Alan / Heffernan, Jane M

Bulletin of mathematical biology

2023 Volume 85, Issue 5, Page(s) 32

Abstract: One of the driving concerns during any epidemic is the strain on the healthcare system. As we have seen many times over the globe with the COVID-19 pandemic, hospitals and ICUs can quickly become overwhelmed by cases. While strict periods of public ... ...

Abstract	One of the driving concerns during any epidemic is the strain on the healthcare system. As we have seen many times over the globe with the COVID-19 pandemic, hospitals and ICUs can quickly become overwhelmed by cases. While strict periods of public health mitigation have certainly helped decrease incidence and thus healthcare demand, vaccination is the only clear long-term solution. In this paper, we develop a two-module model to forecast the effects of relaxation of non-pharmaceutical intervention and vaccine uptake on daily incidence, and the cascade effects on healthcare demand. The first module is a simple epidemiological model which incorporates non-pharmaceutical intervention, the relaxation of such measures and vaccination campaigns to predict caseloads into the Fall of 2021. This module is then fed into a healthcare module which can forecast the number of doctor visits, the number of occupied hospital beds, number of occupied ICU beds and any excess demand of these. From this module, we can also estimate the length of stay of individuals in ICU. For model verification and forecasting, we use the four most populous Canadian provinces as a case study.
MeSH term(s)	Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; SARS-CoV-2 ; COVID-19 Vaccines ; Pandemics/prevention & control ; Canada ; Mathematical Concepts ; Models, Biological ; Health Services Needs and Demand ; Vaccination
Chemical Substances	COVID-19 Vaccines
Language	English
Publishing date	2023-03-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	184905-0
ISSN	1522-9602 ; 0007-4985 ; 0092-8240
ISSN (online)	1522-9602
ISSN	0007-4985 ; 0092-8240
DOI	10.1007/s11538-023-01130-x
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Article: Evaluation of fluoride levels in bottled water and their contribution to health and teeth problems in the United Arab Emirates.

Abouleish, Mohamed Yehia Z

The Saudi dental journal

2016 Volume 28, Issue 4, Page(s) 194–202

Abstract: Fluoride is needed for better health, yet if ingested at higher levels it may lead to health problems. Fluoride can be obtained from different sources, with drinking water being a major contributor. In the United Arab Emirates (UAE), bottled water is the ...

Abstract	Fluoride is needed for better health, yet if ingested at higher levels it may lead to health problems. Fluoride can be obtained from different sources, with drinking water being a major contributor. In the United Arab Emirates (UAE), bottled water is the major source for drinking. The aim of this research is to measure fluoride levels in different bottled water brands sold in UAE, to determine whether fluoride contributes to better health or health problems. The results were compared to international and local standards. Fluoride was present in seven out of 23 brands. One brand exhibited high fluoride levels, which exceeded all standards, suggesting it may pose health problems. Other brands were either below or above standards, suggesting either contribution to better health or health problems, depending on ingested amount. A risk assessment suggested a potential for non-cancer effects from some brands. The results were compared to fluoride levels in bottled water sold in UAE and neighboring countries (e.g. Saudi Arabia, Qatar, Kuwait, and Bahrain), over 24 years, to reflect on changes in fluoride levels in bottled water in this region. The research presents the need for creating, stricter regulations that require careful fluoride monitoring and new regulations that require listing fluoride level on the bottled water label, internationally and regionally. The research will have local and global health impact, as bottled water sold in UAE and neighboring countries, is produced locally and imported from international countries, e.g. Switzerland, the USA, France, Italy, New Zealand, and Fiji.
Language	English
Publishing date	2016-10-08
Publishing country	Saudi Arabia
Document type	Journal Article
ZDB-ID	1058421-3
ISSN	1658-3558 ; 1013-9052
ISSN (online)	1658-3558
ISSN	1013-9052
DOI	10.1016/j.sdentj.2016.08.002
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Article ; Online: Comparison of central-line-associated bloodstream infections between central venous catheters lined by combined chlorhexidine and silver sulfadiazine versus silver ionotrophes alone: A before-after-before retrospective study - CORRIGENDUM.

Abouleish, Youssef Z / Oldfield, Edward C / Marik, Paul E

Infection control and hospital epidemiology

2020 Volume 42, Issue 2, Page(s) 251

Language	English
Publishing date	2020-12-17
Publishing country	United States
Document type	Journal Article ; Published Erratum
ZDB-ID	639378-0
ISSN	1559-6834 ; 0195-9417 ; 0899-823X
ISSN (online)	1559-6834
ISSN	0195-9417 ; 0899-823X
DOI	10.1017/ice.2020.1381
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Article ; Online: Comparison of central-line-associated bloodstream infections between central venous catheters lined by combined chlorhexidine and silver sulfadiazine versus silver ionotrophes alone: A before-after-before retrospective study.

Abouleish, Youssef Z / Oldfield, Edward C / Marik, Paul E

Infection control and hospital epidemiology

2020 Volume 42, Issue 2, Page(s) 225–227

Abstract: A before-after-before direct comparison between catheters lined with chlorhexidine and silver sulfadiazine (CHSS) versus silver ionotrophes (SI) with a primary objective of comparison of rate of central-line-associated infection (CLABSI) in three 10- ... ...

Abstract	A before-after-before direct comparison between catheters lined with chlorhexidine and silver sulfadiazine (CHSS) versus silver ionotrophes (SI) with a primary objective of comparison of rate of central-line-associated infection (CLABSI) in three 10-month windows. The CHSS catheters were associated with a lower rate of CLABSI.
MeSH term(s)	Anti-Infective Agents, Local ; Catheter-Related Infections/epidemiology ; Catheter-Related Infections/prevention & control ; Catheterization, Central Venous/adverse effects ; Central Venous Catheters/adverse effects ; Chlorhexidine ; Humans ; Retrospective Studies ; Sepsis ; Silver ; Silver Sulfadiazine
Chemical Substances	Anti-Infective Agents, Local ; Silver (3M4G523W1G) ; Chlorhexidine (R4KO0DY52L) ; Silver Sulfadiazine (W46JY43EJR)
Language	English
Publishing date	2020-09-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	639378-0
ISSN	1559-6834 ; 0195-9417 ; 0899-823X
ISSN (online)	1559-6834
ISSN	0195-9417 ; 0899-823X
DOI	10.1017/ice.2020.423
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Article ; Online: Evolutionary relevance of metabolite production in relation to marine sponge bacteria symbiont.

Hamoda, Alshaimaa M / Hamdy, Rania / Fayed, Bahgat / Abouleish, Mohamed / Sulaiman, Ashna / Hamad, Mohamad / Soliman, Sameh S M

Applied microbiology and biotechnology

2023 Volume 107, Issue 16, Page(s) 5225–5240

Abstract: Sponges are habitats for a diverse community of microorganisms. Sponges provide shelter, whereas microbes provide a complementary defensive mechanism. Here, a symbiotic bacterium, identified as Bacillus spp., was isolated from a marine sponge following ... ...

Abstract	Sponges are habitats for a diverse community of microorganisms. Sponges provide shelter, whereas microbes provide a complementary defensive mechanism. Here, a symbiotic bacterium, identified as Bacillus spp., was isolated from a marine sponge following culture enrichment. Fermentation-assisted metabolomics using thin-layer chromatography (TLC) and gas chromatography-mass spectrometry (GC-MS) indicated that marine simulated nutrition and temperature was the optimum in metabolite production represented by the highest number of metabolites and the diverse chemical classes when compared to other culture media. Following large-scale culture in potato dextrose broth (PDB) and dereplication, compound M1 was isolated and identified as octadecyl-1-(2',6'-di-tert-butyl-1'-hydroxyphenyl) propionate. M1, at screening concentrations up to 10 mg/ml, showed no activity against prokaryotic bacteria including Staphylococcus aureus and Escherichia coli, while 1 mg/ml of M1 was sufficient to cause a significant killing effect on eukaryotic cells including Candida albicans, Candida auris, and Rhizopus delemar fungi and different mammalian cells. M1 exhibited MIC
MeSH term(s)	Animals ; Porifera ; Bacteria/metabolism ; Antifungal Agents/chemistry ; Biological Evolution ; Bacillus ; Candida albicans ; Mammals
Chemical Substances	Antifungal Agents
Language	English
Publishing date	2023-06-26
Publishing country	Germany
Document type	Journal Article
ZDB-ID	392453-1
ISSN	1432-0614 ; 0171-1741 ; 0175-7598
ISSN (online)	1432-0614
ISSN	0171-1741 ; 0175-7598
DOI	10.1007/s00253-023-12649-3
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Article ; Online: Trihalomethane formation potential of aquatic and terrestrial fulvic and humic acids: Sorption on activated carbon.

Abouleish, Mohamed Y Z / Wells, Martha J M

The Science of the total environment

2015 Volume 521-522, Page(s) 293–304

Abstract: Humic substances (HSs) are precursors for the formation of hazardous disinfection by-products (DBPs) during chlorination of water. Various surrogate parameters have been used to investigate the generation of DBPs by HS precursors and the removal of these ...

Abstract	Humic substances (HSs) are precursors for the formation of hazardous disinfection by-products (DBPs) during chlorination of water. Various surrogate parameters have been used to investigate the generation of DBPs by HS precursors and the removal of these precursors by activated carbon treatment. Dissolved organic carbon (DOC)- and ultraviolet absorbance (UVA254)-based isotherms are commonly reported and presumed to be good predictors of the trihalomethane formation potential (THMFP). However, THMFP-based isotherms are rarely published such that the three types of parameters have not been compared directly. Batch equilibrium experiments on activated carbon were used to generate constant-initial-concentration sorption isotherms for well-characterized samples obtained from the International Humic Substances Society (IHSS). HSs representing type (fulvic acid [FA], humic acid [HA]), origin (aquatic, terrestrial), and geographical source (Nordic, Suwannee, Peat, Soil) were examined at pH6 and pH9. THMFP-based isotherms were generated and compared to determine if DOC- and UVA254-based isotherms were good predictors of the THMFP. The sorption process depended on the composition of the HSs and the chemical nature of the activated carbon, both of which were influenced by pH. Activated carbon removal of THM-precursors was pH- and HS-dependent. In some instances, the THMFP existed after UVA254 was depleted.
MeSH term(s)	Benzopyrans/chemistry ; Charcoal ; Disinfection ; Humic Substances/analysis ; Models, Chemical ; Trihalomethanes/analysis ; Trihalomethanes/chemistry ; Water Pollutants, Chemical/analysis ; Water Pollutants, Chemical/chemistry ; Water Purification
Chemical Substances	Benzopyrans ; Humic Substances ; Trihalomethanes ; Water Pollutants, Chemical ; Charcoal (16291-96-6) ; fulvic acid (XII14C5FXV)
Language	English
Publishing date	2015-07-15
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2015.03.090
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Article: Trihalomethane formation potential of aquatic and terrestrial fulvic and humic acids: Sorption on activated carbon

Abouleish, Mohamed Y.Z / Martha J.M. Wells

Science of the total environment. 2015 July 15, v. 521-522

2015

Abstract	Humic substances (HSs) are precursors for the formation of hazardous disinfection by-products (DBPs) during chlorination of water. Various surrogate parameters have been used to investigate the generation of DBPs by HS precursors and the removal of these precursors by activated carbon treatment. Dissolved organic carbon (DOC)- and ultraviolet absorbance (UVA254)-based isotherms are commonly reported and presumed to be good predictors of the trihalomethane formation potential (THMFP). However, THMFP-based isotherms are rarely published such that the three types of parameters have not been compared directly. Batch equilibrium experiments on activated carbon were used to generate constant-initial-concentration sorption isotherms for well-characterized samples obtained from the International Humic Substances Society (IHSS). HSs representing type (fulvic acid [FA], humic acid [HA]), origin (aquatic, terrestrial), and geographical source (Nordic, Suwannee, Peat, Soil) were examined at pH6 and pH9. THMFP-based isotherms were generated and compared to determine if DOC- and UVA254-based isotherms were good predictors of the THMFP. The sorption process depended on the composition of the HSs and the chemical nature of the activated carbon, both of which were influenced by pH. Activated carbon removal of THM-precursors was pH- and HS-dependent. In some instances, the THMFP existed after UVA254 was depleted.
Keywords	absorbance ; activated carbon ; byproducts ; chlorination ; disinfection ; dissolved organic carbon ; fulvic acids ; humic acids ; pH ; peat ; soil ; sorption ; sorption isotherms
Language	English
Dates of publication	2015-0715
Size	p. 293-304.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2015.03.090
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Article ; Online: Importance of Environmental Factors on Production of Computationally- Defined Natural Molecules against COVID-19 Pandemic.

Abouleish, Mohamed / El-Keblawy, Ali / Mosa, Kareem A / Soliman, Sameh S M

Current topics in medicinal chemistry

2020 Volume 20, Issue 22, Page(s) 1958–1961

MeSH term(s)	Betacoronavirus/drug effects ; Betacoronavirus/isolation & purification ; Biological Products/therapeutic use ; COVID-19 ; Computational Biology/methods ; Coronavirus Infections/drug therapy ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Environment ; Humans ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; SARS-CoV-2
Chemical Substances	Biological Products
Keywords	covid19
Language	English
Publishing date	2020-10-11
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	2064823-6
ISSN	1873-4294 ; 1568-0266
ISSN (online)	1873-4294
ISSN	1568-0266
DOI	10.2174/156802662022200917110430
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Article ; Online: Antibacterial effects of octadecyl trimethylammonium micelle-clay complex against bacterial eye pathogens: potential as a contact lens disinfectant.

Siddiqui, Ruqaiyyah / Shah, Rida Arshad / Akbar, Noor / Khamis, Mustafa / Ibrahim, Taleb / Abouleish, Mohamed Yehia / Khan, Naveed Ahmed

International ophthalmology

2021 Volume 42, Issue 3, Page(s) 939–944

Abstract: ... aeruginosa, S. epidermidis, and M. luteus. Cytotoxicity assays revealed that ODTMA-clay complex exhibited ...

Abstract	Aim: In this study, we utilized a micelle-clay complex composed of the surfactant octadecyltrimethylammonium bromide and montmorillonite clay and evaluated its antibacterial effects. Methods: Using Pseudomonas aeruginosa, Staphylococcus epidermidis, and Micrococcus luteus, bactericidal assays were performed to determine the effects of ODTMA-clay complex on the viability of bacterial pathogen at various doses and different intervals of time. Cytotoxicity assays were performed to investigate ODTMA-clay complex effects on human cells, as determined by release of intracellular lactate dehydrogenase. Results: The results revealed that ODTMA-clay complex abolished bacterial viability at 100 μg/mL within 45 min against P. aeruginosa, S. epidermidis, and M. luteus. Cytotoxicity assays revealed that ODTMA-clay complex exhibited minimal toxicity of the human cells. Conclusion: Rapid and potent antibacterial effects of ODTMA micelle-clay complex were observed in vitro; however, research is needed to determine precise formulation of contact lens disinfectants comprising ODTMA micelle-clay complex. Additionally, studies should be conducted using in vivo models of keratitis, progressing to pre-clinical and clinical trials. ODTMA micelle-clay complex is an ideal candidate to be incorporated in a novel contact lens disinfectant given the cost-effectiveness and ease of application and can be incorporated as an effective preventative strategy.
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Clay ; Contact Lens Solutions/pharmacology ; Contact Lenses ; Disinfectants/pharmacology ; Humans ; Micelles ; Pseudomonas aeruginosa
Chemical Substances	Anti-Bacterial Agents ; Contact Lens Solutions ; Disinfectants ; Micelles ; Clay (T1FAD4SS2M)
Language	English
Publishing date	2021-10-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	800087-6
ISSN	1573-2630 ; 0165-5701
ISSN (online)	1573-2630
ISSN	0165-5701
DOI	10.1007/s10792-021-02075-7
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