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  1. Article ; Online: Innovations and Challenges in Implant-Free Breast Augmentation: Moving Towards Safer, Personalized Plastic Surgery.

    Guo, Qirui / Li, Wenbo

    Aesthetic plastic surgery

    2024  

    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Letter
    ZDB-ID 532791-x
    ISSN 1432-5241 ; 0364-216X
    ISSN (online) 1432-5241
    ISSN 0364-216X
    DOI 10.1007/s00266-024-04013-1
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1296: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Revisiting the link between body composition and lung function in youth: A critical analysis of methodological and demographic considerations.

    Guo, Qirui / Li, Wenbo

    Clinical nutrition (Edinburgh, Scotland)

    2024  

    Language English
    Publishing date 2024-02-28
    Publishing country England
    Document type Letter
    ZDB-ID 604812-2
    ISSN 1532-1983 ; 0261-5614
    ISSN (online) 1532-1983
    ISSN 0261-5614
    DOI 10.1016/j.clnu.2024.02.027
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    Zs.A 1774: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Letter to the Editor: Is right heart assessment vital for evaluating terlipressin-related outcomes in hepatorenal syndrome-acute kidney injury?

    Guo, Qirui / Wang, Jie / Wang, Guangjian / Wang, Xiaoting

    Hepatology (Baltimore, Md.)

    2024  

    Language English
    Publishing date 2024-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604603-4
    ISSN 1527-3350 ; 0270-9139
    ISSN (online) 1527-3350
    ISSN 0270-9139
    DOI 10.1097/HEP.0000000000000832
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1660: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: SPANN: annotating single-cell resolution spatial transcriptome data with scRNA-seq data.

    Yuan, Musu / Wan, Hui / Wang, Zihao / Guo, Qirui / Deng, Minghua

    Briefings in bioinformatics

    2024  Volume 25, Issue 2

    Abstract: Motivation: The rapid development of spatial transcriptome technologies has enabled researchers to acquire single-cell-level spatial data at an affordable price. However, computational analysis tools, such as annotation tools, tailored for these data ... ...

    Abstract Motivation: The rapid development of spatial transcriptome technologies has enabled researchers to acquire single-cell-level spatial data at an affordable price. However, computational analysis tools, such as annotation tools, tailored for these data are still lacking. Recently, many computational frameworks have emerged to integrate single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics datasets. While some frameworks can utilize well-annotated scRNA-seq data to annotate spatial expression patterns, they overlook critical aspects. First, existing tools do not explicitly consider cell type mapping when aligning the two modalities. Second, current frameworks lack the capability to detect novel cells, which remains a key interest for biologists.
    Results: To address these problems, we propose an annotation method for spatial transcriptome data called SPANN. The main tasks of SPANN are to transfer cell-type labels from well-annotated scRNA-seq data to newly generated single-cell resolution spatial transcriptome data and discover novel cells from spatial data. The major innovations of SPANN come from two aspects: SPANN automatically detects novel cells from unseen cell types while maintaining high annotation accuracy over known cell types. SPANN finds a mapping between spatial transcriptome samples and RNA data prototypes and thus conducts cell-type-level alignment. Comprehensive experiments using datasets from various spatial platforms demonstrate SPANN's capabilities in annotating known cell types and discovering novel cell states within complex tissue contexts.
    Availability: The source code of SPANN can be accessed at https://github.com/ddb-qiwang/SPANN-torch.
    Contact: dengmh@math.pku.edu.cn.
    MeSH term(s) Transcriptome ; Single-Cell Gene Expression Analysis ; Sequence Analysis, RNA/methods ; Single-Cell Analysis/methods ; Gene Expression Profiling/methods ; Software
    Language English
    Publishing date 2024-01-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2068142-2
    ISSN 1477-4054 ; 1467-5463
    ISSN (online) 1477-4054
    ISSN 1467-5463
    DOI 10.1093/bib/bbad533
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6262: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  5. Article ; Online: Superassembled MXene-carboxymethyl chitosan nanochannels for the highly sensitive recognition and detection of copper ions.

    Hu, Xiaomeng / Zhou, Shan / Zhang, Xin / Zeng, Hui / Guo, Yaxin / Xu, Yeqing / Liang, Qirui / Wang, Jinqiang / Jiang, Lei / Kong, Biao

    The Analyst

    2024  Volume 149, Issue 5, Page(s) 1464–1472

    Abstract: Copper ions ( ... ...

    Abstract Copper ions (Cu
    MeSH term(s) Copper ; Chitosan/chemistry ; Trace Elements ; Ions/chemistry ; Nitrites ; Transition Elements
    Chemical Substances Copper (789U1901C5) ; Chitosan (9012-76-4) ; MXene ; Trace Elements ; Ions ; Nitrites ; Transition Elements
    Language English
    Publishing date 2024-02-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d3an02190d
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    Zs.A 2423: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Cystatin C is associated with poor survival in amyotrophic lateral sclerosis patients.

    Jiang, Qirui / Guo, Yuan / Yang, Tianmi / Li, Shirong / Hou, Yanbing / Lin, Junyu / Xiao, Yi / Ou, Ruwei / Wei, Qianqian / Shang, Huifang

    Frontiers in neuroscience

    2024  Volume 17, Page(s) 1309568

    Abstract: Background: Cystatin C (CysC) levels in amyotrophic lateral sclerosis (ALS) have been found changes, however, the associations between serum CysC levels and the progression and survival of ALS remain largely unknown.: Methods: A total of 1,086 ALS ... ...

    Abstract Background: Cystatin C (CysC) levels in amyotrophic lateral sclerosis (ALS) have been found changes, however, the associations between serum CysC levels and the progression and survival of ALS remain largely unknown.
    Methods: A total of 1,086 ALS patients and 1,026 sex-age matched healthy controls (HCs) were enrolled in this study. Serum CysC, other renal function, and metabolic parameters were measured. Correlation analysis and binary logistic regression were used to explore the factors related to serum CysC. Kaplan-Meier curve and Cox regression model were used for survival analysis.
    Results: CysC levels were significantly higher in ALS patients compared to HCs (0.94 vs. 0.85 mg/L,
    Conclusion: CysC levels in ALS patients were higher compared to HCs. Higher CysC levels were associated with greater disease severity, faster progression rate and shorter survival, needing early intervention.
    Language English
    Publishing date 2024-01-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2023.1309568
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  7. Article ; Online: Effect of Bond-Slip on Dynamic Response of FRP-Confined RC Columns with Non-Linear Damping

    Kun Guo / Qirui Guo / Yuanfeng Wang

    Applied Sciences, Vol 11, Iss 5, p

    2021  Volume 2124

    Abstract: As a composite material, the damping energy consumption mechanism of fiber reinforced polymer-confined reinforced concrete (FRP-C RC) structure is very complex. In previous dynamic calculation models, the bond-slip effect for steel bars was often ignored, ...

    Abstract As a composite material, the damping energy consumption mechanism of fiber reinforced polymer-confined reinforced concrete (FRP-C RC) structure is very complex. In previous dynamic calculation models, the bond-slip effect for steel bars was often ignored, which would lead to a considerable error in the response of the FRP-C RC structures. In this paper, a new numerical model of FRP-C RC columns considering the bond-slip for steel bars is established using a zero-length element and nonlinear beam-column elements in the OpenSees software, and the results of the model are verified by experimental results. Based on the complex damping theory, the loss factor expression and nonlinear damping model of FRP-C RC columns with the bond slip effect are proposed. Finally, the dynamic response of FRP-C RC columns with nonlinear damping under harmonic load is calculated and compared with the results available in literature. The results show that the proposed model considering steel bars’ bond-slip can provide better prediction for dynamic response of FRP-C RC columns and make the future seismic design of FRP-C RC columns safer.
    Keywords FRP-C RC columns ; bond-slip ; zero-length element ; nonlinear damping ; dynamic response ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 621
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Polystyrene microplastics induced inflammation with activating the TLR2 signal by excessive accumulation of ROS in hepatopancreas of carp (Cyprinus carpio)

    Jie Cui / Yanhe Zhang / Lin Liu / Qirui Zhang / Shiwen Xu / Meng-yao Guo

    Ecotoxicology and Environmental Safety, Vol 251, Iss , Pp 114539- (2023)

    2023  

    Abstract: Polystyrene microplastics (PS-MPs) affect the immune defense function on carp (Cyprinus carpio). The PS-MPs model of carp was established by feeding with PS-MPs particle size of 8 µm and concentration of 1000 ng/L water. Hepatopancreas function test ... ...

    Abstract Polystyrene microplastics (PS-MPs) affect the immune defense function on carp (Cyprinus carpio). The PS-MPs model of carp was established by feeding with PS-MPs particle size of 8 µm and concentration of 1000 ng/L water. Hepatopancreas function test revealed the activities of AKP, ALT, AST and LDH abnormal increase. PS-MPs induced tissue damage and lead to abnormal hepatopancreas function. The PS-MPs also induced a oxidative stress with the antioxidant enzymes SOD, CAT, GSH-PX, and T-AOC activities decreasing and reactive oxygen species (ROS) excessive accumulation. PS-MPs activated the Toll like receptor-2 (TLR2) signaling pathway. The mRNA and protein expressions of TLR2, Myeloid differentiation primary response 88 (MyD88), tumor necrosis factor receptor-associated factor 6 (TRAF6), NF-κB p65, Tumor necrosis factor (TNF-α), Interleukin-1β (IL-1β), Inducible Nitric Oxide Synthase (iNOS), and cycooxygenase 2(COX2) was revealed increased in both hepatopancreas and hepatocytes with the qPCR and Western blotting analysis mode. ELISA showed the expressions of TNF-α, IL-1β, iNOS, and COX2 inflammatory molecule were increased in both hepatopancreas and hepatocytes. The results showed that PS-MPs caused a serious injure in the hepatopancreas and brought serious effects on the inflammatory response of carp. The present study displayed the harm caused by PS-MPs in freshwater fish, and provided some suggestions and references for toxicological studies of microplastics in freshwater environment.
    Keywords Liver ; Toxicology ; Oxidative stress ; Polystyrene microplastics ; Cell signaling ; Environmental pollution ; TD172-193.5 ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Prevalence and Molecular Characterization of

    Gao, Haihui / Liang, Gaoxing / Su, Na / Li, Qirui / Wang, Dong / Wang, Jiandong / Zhao, Long / Kang, Xiaodong / Guo, Kangkang

    Animals : an open access journal from MDPI

    2023  Volume 13, Issue 12

    Abstract: ... ...

    Abstract Cryptosporidium
    Language English
    Publishing date 2023-06-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani13121983
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  10. Article ; Online: Effect of phosphorus concentration and light/dark condition on phosphorus uptake and distribution with microalgae.

    Wu, Qirui / Guo, Liang / Li, Xunzhou / Wang, Yu

    Bioresource technology

    2021  Volume 340, Page(s) 125745

    Abstract: In this study, the effects of P concentration and light/dark condition on the distribution of P in microalgae were tracked with Scenedesmus sp.393. Results showed that different culture conditions affected the accumulation capacity and transformation of ... ...

    Abstract In this study, the effects of P concentration and light/dark condition on the distribution of P in microalgae were tracked with Scenedesmus sp.393. Results showed that different culture conditions affected the accumulation capacity and transformation of P in intracellular polymeric substances (IPS), extracellular polymeric substances (EPS), and soluble microbial products (SMP). At low P concentration (0.70 mg P/L), inorganic phosphorus (IP) absorbed in EPS (19.40%) and organic phosphorus (OP) accumulated in IPS (70.98%) were mainly P forms in microalgae. High P concentration (>21.42 mg P/L) promoted the luxury uptake and accumulation of IP by IPS, and the conversion of IP to OP. However, the adsorption of IP by EPS was inhibited when exposed to high external P concentration. Continuous illumination promoted the microalgae growth, and dark condition stimulated the P accumulation in microalgae biomass. The results of this study could provide valuable information for P recovery with microalgae.
    MeSH term(s) Biomass ; Extracellular Polymeric Substance Matrix ; Microalgae ; Nitrogen ; Phosphorus ; Scenedesmus
    Chemical Substances Phosphorus (27YLU75U4W) ; Nitrogen (N762921K75)
    Language English
    Publishing date 2021-08-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 1065195-0
    ISSN 1873-2976 ; 0960-8524
    ISSN (online) 1873-2976
    ISSN 0960-8524
    DOI 10.1016/j.biortech.2021.125745
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    Z 3258: Show issues

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