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  1. Book: Dental functional morphology

    Lucas, Peter W.

    how teeth work

    2004  

    Author's details Peter W. Lucas
    Keywords Säugetiere ; Zahn ; Evolution ; Anthropologie ; Funktionsmorphologie
    Subject Funktionale Morphologie ; Funktionelle Morphologie ; Morphologie ; Menschenkunde ; Abstammung ; Mammalia ; Säuger ; Säugetier
    Language English
    Size XVI, 355 S. : Ill., graph. Darst.
    Publisher Cambridge Univ. Press
    Publishing place Cambridge u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT013927940
    ISBN 0-521-56236-8 ; 978-0-521-56236-2
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2004 A 2506 order for loan Magazin

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  2. Article ; Online: Toughness and fiber content of major leaf foods of Japanese macaques (Macaca fuscata yakui) in Yakushima.

    Hill, David A / Lucas, Peter W

    American journal of primatology

    2019  Volume 38, Issue 3, Page(s) 221–231

    Abstract: During the spring, Japanese macaques in Yakushima feed predominantly on mature leaves of trees, vines, and ferns. They are selective in which parts of leaves they eat, and this study examines potential cues and consequences of typical patterns of ... ...

    Abstract During the spring, Japanese macaques in Yakushima feed predominantly on mature leaves of trees, vines, and ferns. They are selective in which parts of leaves they eat, and this study examines potential cues and consequences of typical patterns of selection. Toughness and fiber content (NDF) were assessed for 13 of the major leaf-food species from samples collected in the spring of 1994. The toughness of the petiole, the midrib, and two parts of the lamina were tested separately. Petioles were generally the toughest part of the leaf, followed by the midribs. For both midrib and lamina, there was a positive correlation between toughness and fiber content, but the toughness of midribs was at least three times that of laminae at similar fiber contents. A clear relationship was found between the toughness of plant parts and whether or not they were eaten: no plant parts with a toughness greater than 2,300 J m
    Language English
    Publishing date 2019-12-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1495834-X
    ISSN 1098-2345 ; 0275-2565
    ISSN (online) 1098-2345
    ISSN 0275-2565
    DOI 10.1002/(SICI)1098-2345(1996)38:3<221::AID-AJP3>3.0.CO;2-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Switching the spin cycloid in BiFeO

    Meisenheimer, Peter / Moore, Guy / Zhou, Shiyu / Zhang, Hongrui / Huang, Xiaoxi / Husain, Sajid / Chen, Xianzhe / Martin, Lane W / Persson, Kristin A / Griffin, Sinéad / Caretta, Lucas / Stevenson, Paul / Ramesh, Ramamoorthy

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 2903

    Abstract: Bismuth ferrite ( ... ...

    Abstract Bismuth ferrite (BiFeO
    Language English
    Publishing date 2024-04-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-47232-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Diverse material properties and morphology of moth proboscises relates to the feeding habits of some macromoth and other lepidopteran lineages.

    Bast, Elaine M / Marshall, Natalie T / Myers, Kendall O / Marsh, Lucas W / Hurtado, Martin Walschburger / Van Zandt, Peter A / Lehnert, Matthew S

    Interface focus

    2024  Volume 14, Issue 2, Page(s) 20230051

    Abstract: Insects have evolved unique structures that host a diversity of material and mechanical properties, and the mouthparts (proboscis) of butterflies and moths (Lepidoptera) are no exception. Here, we examined proboscis morphology and material properties ... ...

    Abstract Insects have evolved unique structures that host a diversity of material and mechanical properties, and the mouthparts (proboscis) of butterflies and moths (Lepidoptera) are no exception. Here, we examined proboscis morphology and material properties from several previously unstudied moth lineages to determine if they relate to flower visiting and non-flower visiting feeding habits. Scanning electron microscopy and three-dimensional imaging were used to study proboscis morphology and assess surface roughness patterns on the galeal surface, respectively. Confocal laser scanning microscopy was used to study patterns of cuticular autofluorescence, which was quantified with colour analysis software. We found that moth proboscises display similar autofluorescent signals and morphological patterns in relation to feeding habits to those previously described for flower and non-flower visiting butterflies. The distal region of proboscises of non-flower visitors is brush-like for augmented capillarity and exhibited blue autofluorescence, indicating the possible presence of resilin and increased flexibility. Flower visitors have smoother proboscises and show red autofluorescence, an indicator of high sclerotization, which is adaptive for floral tube entry. We propose the lepidopteran proboscis as a model structure for understanding how insects have evolved a suite of morphological and material adaptations to overcome the challenges of acquiring fluids from diverse sources.
    Language English
    Publishing date 2024-04-12
    Publishing country England
    Document type Journal Article
    ISSN 2042-8898
    ISSN 2042-8898
    DOI 10.1098/rsfs.2023.0051
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  5. Article ; Online: Acuity Comparison Methods via Timed Test-Retest Precision of Matching-Card e-ETDRS Compared to PDI Check in Treated Amblyopes and Superb Normals.

    Hepler, Lucas E / Martin, Samuel J / Fuglseth, Kennedy / Cuddihee, Laney / Giannulis, Peter / Arnold, Robert W

    Clinical optometry

    2023  Volume 15, Page(s) 81–95

    Abstract: Purpose: Existing and emerging visual acuity methods like dynamic and dichoptic presentation, preferential looking and eye tracking promise to afford better and earlier assessment in children with and without amblyopia so we propose methods needed to ... ...

    Abstract Purpose: Existing and emerging visual acuity methods like dynamic and dichoptic presentation, preferential looking and eye tracking promise to afford better and earlier assessment in children with and without amblyopia so we propose methods needed to easily evaluate and compare their metrics.
    Subjects and methods: Patients older than 8 years with treated amblyopia and superb vision (logMAR -0.1 to -0.3) normals performed timed, patched eETDRS with Sloan matching card at 3.00 m and PDI Check dichoptic near rivalry dynamic test to demonstrate test re-Test and compared disparate acuity with intraclass correlation (ICC) and Bland Altman 95% limits of agreement (LOA) to generate a simple method of qualifying acuity test matching.
    Results: 26 amblyopic patients and 11 superb-vision normals performed eETDRS retest, PDI Check retest and combined ICC of 0.98, 0.60 and 0.27, respectively, and Bland Altman LOA of 0.24, 2.06 and 2.28 logMAR. The time to test one eye with eETDRS had median (interquartile range; IQR) duration of 280 (205 to 346) seconds, while the PDI Check autostereoscopic dichoptic for both eyes only took 39 (30 to 47) seconds. Optimum ICC and LOA for visual acuity comparison should be >0.95 and <0.3 logMAR, whereas "good" ICC and should be 0.75-0.89 ICC and 1.0-1.49 logMAR LOA.
    Conclusion: Superb vision subjects (logMAR < -0.1) and treated amblyopic patients confirmed optimum comparable eETDRS, and fair test re-Test PDI Check but suppression on near dichoptic testing confirmed disparity compared to optimized eETDRS distance acuity.
    Language English
    Publishing date 2023-05-02
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2587459-7
    ISSN 1179-2752 ; 1179-2752
    ISSN (online) 1179-2752
    ISSN 1179-2752
    DOI 10.2147/OPTO.S409358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Interactions between native and invasive species

    Lucas A. Wauters / Peter W. W. Lurz / Francesca Santicchia / Claudia Romeo / Nicola Ferrari / Adriano Martinoli / John Gurnell

    Frontiers in Ecology and Evolution, Vol

    A systematic review of the red squirrel-gray squirrel paradigm

    2023  Volume 11

    Abstract: The eastern gray squirrel (Sciurus carolinensis) has been labeled as one of the 100 worst invasive alien species by the IUCN. In Europe, the species has been introduced to Britain, Ireland and Italy, and its subsequent spread has resulted in wide-scale ... ...

    Abstract The eastern gray squirrel (Sciurus carolinensis) has been labeled as one of the 100 worst invasive alien species by the IUCN. In Europe, the species has been introduced to Britain, Ireland and Italy, and its subsequent spread has resulted in wide-scale extinction of native Eurasian red squirrels (Sciurus vulgaris) from the areas colonized by the gray squirrel. This replacement of a native by an alien competitor is one of the best documented cases of the devastating effects of biological invasions on native fauna. To understand how this replacement occurs, we present a systematic review of the literature on competition and interactions between red and gray squirrels. We describe the patterns of red and gray squirrel distribution in those parts of Europe where gray squirrels occur and summarize the evidence on the different processes and mechanisms determining the outcome of competition between the native and alien species including the influence of predators and pathogens. Some of the drivers behind the demise of the red squirrel have been intensively studied and documented in the past 30 years, but recent field studies and mathematical models revealed that the mechanisms underlying the red-gray paradigm are more complex than previously thought and affected by landscape-level processes. Therefore, we consider habitat type and multi-species interactions, including host-parasite and predator-prey relationships, to determine the outcome of the interaction between the two species and to better address gray squirrel control efforts.
    Keywords exploitation competition ; apparent competition ; interspecific competition ; Sciurus vulgaris ; Sciurus carolinensis ; mathematical models ; Evolution ; QH359-425 ; Ecology ; QH540-549.5
    Subject code 590
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Visual Assistance in Development and Validation of Bayesian Networks for Clinical Decision Support.

    Muller-Sielaff, Juliane / Beladi, Seyed Behnam / Vrede, Stephanie W / Meuschke, Monique / Lucas, Peter J F / Pijnenborg, Johanna M A / Oeltze-Jafra, Steffen

    IEEE transactions on visualization and computer graphics

    2023  Volume 29, Issue 8, Page(s) 3602–3616

    Abstract: The development and validation of Clinical Decision Support Models (CDSM) based on Bayesian networks (BN) is commonly done in a collaborative work between medical researchers providing the domain expertise and computer scientists developing the decision ... ...

    Abstract The development and validation of Clinical Decision Support Models (CDSM) based on Bayesian networks (BN) is commonly done in a collaborative work between medical researchers providing the domain expertise and computer scientists developing the decision support model. Although modern tools provide facilities for data-driven model generation, domain experts are required to validate the accuracy of the learned model and to provide expert knowledge for fine-tuning it while computer scientists are needed to integrate this knowledge in the learned model (hybrid modeling approach). This generally time-expensive procedure hampers CDSM generation and updating. To address this problem, we developed a novel interactive visual approach allowing medical researchers with less knowledge in CDSM to develop and validate BNs based on domain specific data mainly independently and thus, diminishing the need for an additional computer scientist. In this context, we abstracted and simplified the common workflow in BN development as well as adjusted the workflow to medical experts' needs. We demonstrate our visual approach with data of endometrial cancer patients and evaluated it with six medical researchers who are domain experts in the gynecological field.
    MeSH term(s) Humans ; Decision Support Systems, Clinical ; Bayes Theorem ; Computer Graphics
    Language English
    Publishing date 2023-06-29
    Publishing country United States
    Document type Journal Article
    ISSN 1941-0506
    ISSN (online) 1941-0506
    DOI 10.1109/TVCG.2022.3166071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Benchmarking Thiolate-Driven Photoswitching of Cyanine Dyes.

    Herdly, Lucas / Tinning, Peter W / Geiser, Angéline / Taylor, Holly / Gould, Gwyn W / van de Linde, Sebastian

    The journal of physical chemistry. B

    2023  Volume 127, Issue 3, Page(s) 732–741

    Abstract: Carbocyanines are among the best performing dyes in single-molecule localization microscopy (SMLM), but their performance critically relies on optimized photoswitching buffers. Here, we study the versatile role of thiols in cyanine photoswitching at ... ...

    Abstract Carbocyanines are among the best performing dyes in single-molecule localization microscopy (SMLM), but their performance critically relies on optimized photoswitching buffers. Here, we study the versatile role of thiols in cyanine photoswitching at varying intensities generated in a single acquisition by a microelectromechanical systems (MEMS) mirror placed in the excitation path. The key metrics we have analyzed as a function of the thiolate concentration are photon budget, on-state and off-state lifetimes and the corresponding impact on image resolution. We show that thiolate acts as a concentration bandpass filter for the maximum achievable resolution and determine a minimum of ∼1 mM is necessary to facilitate SMLM measurements. We also identify a concentration bandwidth of 1-16 mM in which the photoswitching performance can be balanced between high molecular brightness and high off-time to on-time ratios. Furthermore, we monitor the performance of the popular oxygen scavenger system based on glucose and glucose oxidase over time and show simple measures to avoid acidification during prolonged measurements. Finally, the impact of buffer settings is quantitatively tested on the distribution of the glucose transporter protein 4 within the plasma membrane of adipocytes. Our work provides a general strategy for achieving optimal resolution in SMLM with relevance for the development of novel buffers and dyes.
    MeSH term(s) Benchmarking ; Fluorescent Dyes ; Carbocyanines ; Single Molecule Imaging/methods ; Quinolines
    Chemical Substances Fluorescent Dyes ; Carbocyanines ; Quinolines
    Language English
    Publishing date 2023-01-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/acs.jpcb.2c06872
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Cooking clue to human dietary diversity.

    Lucas, Peter W

    Proceedings of the National Academy of Sciences of the United States of America

    2011  Volume 108, Issue 48, Page(s) 19101–19102

    MeSH term(s) Animals ; Energy Intake/physiology ; Food Handling/methods ; Food Handling/statistics & numerical data ; Humans ; Male ; Meat
    Language English
    Publishing date 2011-11-16
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.1116813108
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1148: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article ; Online: A simulation study of disaggregation regression for spatial disease mapping.

    Arambepola, Rohan / Lucas, Tim C D / Nandi, Anita K / Gething, Peter W / Cameron, Ewan

    Statistics in medicine

    2021  Volume 41, Issue 1, Page(s) 1–16

    Abstract: Disaggregation regression has become an important tool in spatial disease mapping for making fine-scale predictions of disease risk from aggregated response data. By including high resolution covariate information and modeling the data generating process ...

    Abstract Disaggregation regression has become an important tool in spatial disease mapping for making fine-scale predictions of disease risk from aggregated response data. By including high resolution covariate information and modeling the data generating process on a fine scale, it is hoped that these models can accurately learn the relationships between covariates and response at a fine spatial scale. However, validating these high resolution predictions can be a challenge, as often there is no data observed at this spatial scale. In this study, disaggregation regression was performed on simulated data in various settings and the resulting fine-scale predictions are compared to the simulated ground truth. Performance was investigated with varying numbers of data points, sizes of aggregated areas and levels of model misspecification. The effectiveness of cross validation on the aggregate level as a measure of fine-scale predictive performance was also investigated. Predictive performance improved as the number of observations increased and as the size of the aggregated areas decreased. When the model was well-specified, fine-scale predictions were accurate even with small numbers of observations and large aggregated areas. Under model misspecification predictive performance was significantly worse for large aggregated areas but remained high when response data was aggregated over smaller regions. Cross-validation correlation on the aggregate level was a moderately good predictor of fine-scale predictive performance. While these simulations are unlikely to capture the nuances of real-life response data, this study gives insight into the effectiveness of disaggregation regression in different contexts.
    MeSH term(s) Computer Simulation ; Humans
    Language English
    Publishing date 2021-10-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 843037-8
    ISSN 1097-0258 ; 0277-6715
    ISSN (online) 1097-0258
    ISSN 0277-6715
    DOI 10.1002/sim.9220
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