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  1. Article: Tubular carcinoma of the breast: mammographic, sonographic, clinical and pathologic findings.

    Günhan-Bilgen, Işil / Oktay, Ayşenur

    European journal of radiology

    2007  Volume 61, Issue 1, Page(s) 158–162

    Abstract: Purpose: To determine and quantitate the radiological characteristics of tubular carcinoma of the breast, to report clinical and pathologic findings and to define findings at follow-up.: Materials and methods: A retrospective review of records of ... ...

    Abstract Purpose: To determine and quantitate the radiological characteristics of tubular carcinoma of the breast, to report clinical and pathologic findings and to define findings at follow-up.
    Materials and methods: A retrospective review of records of 2872 women who received a diagnosis of breast carcinoma between January 1988 and January 2006 revealed 32 histopathologically proven pure tubular carcinoma of the breast. Analysis included history; findings at physical examination, mammography, and sonography (US) at the time of diagnosis and in postoperative follow-up and histopathological results.
    Results: Fifty-nine percent of the patients (n=19) presented with a palpable mass. The mammographic findings were a mass in 23 (72%), a mass with microcalcifications in 2 (6%), asymmetric focal density in 1 (3%), architectural distortion in 1 (3%) and negative in 5 (16%) of the 32 patients. Most (96%) masses had spiculated margins. US depicted 30 masses in 29 patients, all of which were hypoechoic, mostly (n=27, 90%) with posterior acoustic shadowing. The cancer was clinically occult in 41% (n=13), mammographically occult in 16% (n=5), and sonographically occult in 6% (n=2) of the patients. Histologically, the tumor was multifocal in 3% (n=1) of the patients. Four (13%) patients developed contralateral breast carcinoma at follow-up.
    Conclusion: Tubular carcinoma has a variety of presentations, but it is mostly seen on mammography as a small spiculated mass, and on sonography as an irregular mass with posterior acoustic shadowing. Although tubular carcinoma is known as a well-differentiated tumor with excellent prognosis, the mammographic follow-up of the contralateral breast is important.
    MeSH term(s) Adenocarcinoma/diagnostic imaging ; Adenocarcinoma/epidemiology ; Adenocarcinoma/pathology ; Adult ; Aged ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/epidemiology ; Breast Neoplasms/pathology ; Female ; Humans ; Middle Aged ; Neoplasms, Multiple Primary/diagnostic imaging ; Neoplasms, Multiple Primary/epidemiology ; Neoplasms, Multiple Primary/pathology ; Neoplasms, Second Primary/diagnostic imaging ; Neoplasms, Second Primary/epidemiology ; Neoplasms, Second Primary/pathology ; Prevalence ; Retrospective Studies ; Risk Assessment/methods ; Risk Factors ; Severity of Illness Index ; Turkey/epidemiology ; Ultrasonography, Mammary/statistics & numerical data
    Language English
    Publishing date 2007-01
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2006.08.021
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  2. Article ; Online: Management of microcalcifications developing at the lumpectomy bed after conservative surgery and radiation therapy.

    Günhan-Bilgen, Işil / Oktay, Ayşenur

    AJR. American journal of roentgenology

    2007  Volume 188, Issue 2, Page(s) 393–398

    Abstract: Objective: The purpose of our study was to determine whether the mammographic features (morphology and distribution) of new microcalcifications that develop in women treated with lumpectomy and radiation therapy can allow differentiation of benign ... ...

    Abstract Objective: The purpose of our study was to determine whether the mammographic features (morphology and distribution) of new microcalcifications that develop in women treated with lumpectomy and radiation therapy can allow differentiation of benign changes from recurrent neoplasm.
    Materials and methods: A retrospective review of mammograms of 402 patients who were treated with conservative surgery and radiation therapy between 1987 and 2005 revealed 68 cases of new calcifications (in 66 patients) with follow-up (n = 55) or biopsy (n = 13) results. Analysis included the time between completion of radiation therapy and the appearance of calcifications; location of calcifications relative to the site of the original lesion; the morphology and distribution of calcifications; and changes in number, density, morphology, and rate of change of calcifications.
    Results: The median rate of development after lumpectomy was 24 months (range, 6-84 months) for benign and 52 months (range, 20-90 months) for malignant calcifications. In 63 cases (93%), the new calcifications developed in the same quadrant as the primary tumor. None of the calcifications initially interpreted as BI-RADS category 2 (n = 40/68; 59%) and category 3 (n = 19/68; 28%) represented recurrent disease. Nine (13%) of 68 calcifications were initially classified as BI-RADS category 4 or 5; six (67%) of the nine were malignant and three (33%) were benign at biopsy.
    Conclusion: Newly occurring calcifications in the treated breast are usually benign, and they can be managed conservatively in many cases by using morphology and pattern of distribution as a guide.
    MeSH term(s) Adult ; Breast Neoplasms/epidemiology ; Breast Neoplasms/radiotherapy ; Breast Neoplasms/surgery ; Calcinosis/diagnostic imaging ; Calcinosis/epidemiology ; Female ; Humans ; Incidence ; Mastectomy, Segmental/statistics & numerical data ; Middle Aged ; Neoplasm Recurrence, Local/diagnostic imaging ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/therapy ; Precancerous Conditions/diagnostic imaging ; Precancerous Conditions/epidemiology ; Precancerous Conditions/therapy ; Prognosis ; Radiography ; Risk Assessment/methods ; Risk Factors ; Treatment Outcome
    Language English
    Publishing date 2007-02
    Publishing country United States
    Document type Controlled Clinical Trial ; Journal Article
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/AJR.06.0106
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  3. Article: Paget's disease of the breast: clinical, mammographic, sonographic and pathologic findings in 52 cases.

    Günhan-Bilgen, Işil / Oktay, Ayşenur

    European journal of radiology

    2006  Volume 60, Issue 2, Page(s) 256–263

    Abstract: Purpose: To determine and quantitate radiologic characteristics of Paget's disease of the breast and to report clinical and pathologic findings.: Materials and methods: A retrospective review of records of 2872 women who received a diagnosis of ... ...

    Abstract Purpose: To determine and quantitate radiologic characteristics of Paget's disease of the breast and to report clinical and pathologic findings.
    Materials and methods: A retrospective review of records of 2872 women who received a diagnosis of breast carcinoma between January 1988 and January 2006 revealed 52 histologically proved Paget's disease of the breast. Analysis included history, findings at physical examination, mammography and sonography (US) and histologic type of Paget's disease.
    Results: At physical examination, palpable mass (n=33, 63%), nipple erythema-eczema-ulceration (n=17, 33%) and blood-stained nipple discharge (n=5, 10%) were noted. Among 17 patients who had clinically evident Paget's disease, the mammographic findings were isolated microcalcifications in 3 (18%), mass associated with microcalcifications in 5 (29%), mass in 2 (12%) and negative in 7 (41%) patients. In the 35 patients with clinically inevident Paget's disease, these mammographic findings were 43% (n=15), 34% (n=12), 20% (n=7) and 3% (n=1), respectively. US depicted 43 masses in 35 patients, all of which were lobulated or irregularly contoured, mostly (n=41, 95%) without posterior acoustic shadowing. The cancer was clinically occult in 10% (n=5), mammographically occult in 15% (n=8) and radiologically occult in 13% (n=7) of the 52 patients. Histologically, the tumor was multifocal and/or multicentric in 11 (21%) patients.
    Conclusion: The clinical features of Paget's disease are characteristic and should alert the clinician to the likelihood of an underlying carcinoma, which should be evaluated radiologically. However, as Paget's disease is primarily a clinical diagnosis and mammograms may be negative, screening programs without clinical examination may result with delay in diagnosis. As a result, both clinical and imaging findings are complementary and should be correlated to confirm or exclude a diagnosis of Paget's disease.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Axilla ; Breast Neoplasms/diagnosis ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/pathology ; Calcinosis/diagnosis ; Carcinoma in Situ/diagnosis ; Carcinoma, Ductal, Breast/diagnosis ; Female ; Humans ; Lymphatic Metastasis ; Mammography ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Staging ; Nipples/diagnostic imaging ; Nipples/pathology ; Paget's Disease, Mammary/diagnosis ; Paget's Disease, Mammary/diagnostic imaging ; Paget's Disease, Mammary/pathology ; Retrospective Studies ; Sensitivity and Specificity ; Ultrasonography, Mammary
    Language English
    Publishing date 2006-11
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2006.06.010
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  4. Article: Tubulolobular carcinoma of the breast: clinical, mammographic and sonographic findings.

    Günhan-Bilgen, Işil / Oktay, Ayşenur

    European journal of radiology

    2006  Volume 60, Issue 3, Page(s) 418–424

    Abstract: Purpose: To determine and quantitate radiologic characteristics of tubulolobular carcinoma of the breast and to report clinical and pathologic findings.: Materials and methods: A retrospective review of records of 2872 women who received a diagnosis ... ...

    Abstract Purpose: To determine and quantitate radiologic characteristics of tubulolobular carcinoma of the breast and to report clinical and pathologic findings.
    Materials and methods: A retrospective review of records of 2872 women who received a diagnosis of breast carcinoma between January 1988 and January 2006 revealed 26 histopathologically proven tubulolobular carcinoma of the breast. Analysis included history; findings at physical examination, mammography, and sonography (US) at the time of diagnosis and in postoperative follow-up, and histopathological results.
    Results: At physical examination, palpable mass was present in 85% (n=22) of the patients. The mammographic findings were mass in 17 (65%), asymmetric focal density in 2 (8%), architectural distortion in 2 (8%) and negative mammograms in 5 (19%) of the 26 patients. US depicted 25 masses in 24 patients, all of which were hypoechoic, with spiculated (n=13) or microlobulated (n=12) margins. The cancer was clinically occult in 12% (n=3), mammographically occult in 19% (n=5), and radiologically occult in 4% (n=1) of the patients. Histologically, the mean size of the tumor was 1.7cm and 18 (69%) patients were node negative.
    Conclusion: Tubulolobular carcinoma of the breast usually manifests clinically as a firm, immobile mass and mammographically as a spiculated or ill-defined, irregular, isodense mass without microcalcifications. Common findings on sonography include a homogeneously hypoechoic, spiculated or microlobulated mass with posterior acoustic shadowing or normal acoustic transmission. Tubulolobular carcinoma should be included in the differential diagnosis for breast masses with these imaging features.
    MeSH term(s) Adult ; Aged ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/pathology ; Carcinoma, Lobular/diagnostic imaging ; Carcinoma, Lobular/pathology ; Female ; Humans ; Mammography ; Middle Aged ; Retrospective Studies ; Ultrasonography, Mammary
    Language English
    Publishing date 2006-12
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2006.06.011
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  5. Article: Inflammatory breast carcinoma: mammographic, ultrasonographic, clinical, and pathologic findings in 142 cases.

    Günhan-Bilgen, Işil / Ustün, Esin Emin / Memiş, Ayşenur

    Radiology

    2002  Volume 223, Issue 3, Page(s) 829–838

    Abstract: Purpose: To determine and quantitate radiologic characteristics of inflammatory breast carcinoma and to report clinical and pathologic findings.: Materials and methods: A retrospective review of records of 2,733 women who received a diagnosis of ... ...

    Abstract Purpose: To determine and quantitate radiologic characteristics of inflammatory breast carcinoma and to report clinical and pathologic findings.
    Materials and methods: A retrospective review of records of 2,733 women who received a diagnosis of breast carcinoma between January 1988 and May 2000 revealed 142 histologically proved inflammatory carcinomas. Analysis included history; findings at physical examination, mammography, and ultrasonography (US); and histologic type of inflammatory carcinoma.
    Results: At physical examination, skin changes (n = 115, 81%) were the most common findings. A palpable mass was noted in 62% (n = 88), with axillary lymph node involvement in 68% (n = 96) of the carcinomas. Mammography revealed findings in carcinomas: skin thickening, 84% (n = 119); diffusely increased density, 37% (n = 53); trabecular thickening, 81% (n = 115); mass, 16% (n = 23); asymmetric focal density, 61% (n = 87); microcalcifications, 56% (n = 80); nipple retraction, 43% (n = 61); and axillary lymphadenopathy, 24% (n = 34). US showed changes in carcinomas: skin thickening, 96% (n = 136); parenchymal echogenicity changes, 73% (n = 104); dilated lymphatic channels, 68% (n = 96); solid mass, 80% (n = 114); pectoral muscle invasion, 10% (n = 14); focal areas of parenchymal acoustic shadowing, 37% (n = 52); and axillary lymphadenopathy, 73% (n = 104).
    Conclusion: Presence of isolated inflammatory signs is sufficient to suggest inflammatory breast carcinoma clinically. Inflammatory breast carcinoma has a mammographic pattern of inflammatory changes, such as skin thickening and stromal coarsening and/or diffusely increased breast density with or without an associated mass and/or malignant-type microcalcifications. US is helpful not only in depiction of masses masked by the edema pattern but also in demonstration of skin and pectoral muscle invasion and axillary involvement.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/pathology ; Diagnosis, Differential ; Female ; Humans ; Mammography ; Middle Aged ; Neoplasm Invasiveness ; Palpation ; Physical Examination ; Retrospective Studies ; Ultrasonography, Mammary
    Language English
    Publishing date 2002-06
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.2233010198
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  6. Article: Breast metastasis from low-grade endometrial stromal sarcoma after a 17-year period.

    Günhan-Bilgen, Isil / Memis, Aysenur / Ustün, Esin Emin / Ozdemir, Necmettin

    European radiology

    2002  Volume 12, Issue 12, Page(s) 3023–3025

    Abstract: Metastases to the breast are rare with an incidence of 0.5-3% of patients with extramammary carcinomas. We report a unique case of an endometrial stromal sarcoma metastasizing to the breast after a 17-year-period. Mammographic and ultrasonographic ... ...

    Abstract Metastases to the breast are rare with an incidence of 0.5-3% of patients with extramammary carcinomas. We report a unique case of an endometrial stromal sarcoma metastasizing to the breast after a 17-year-period. Mammographic and ultrasonographic findings with histopathological correlation are described.
    MeSH term(s) Breast Neoplasms/diagnosis ; Breast Neoplasms/secondary ; Disease Progression ; Endometrial Neoplasms/diagnosis ; Endometrial Neoplasms/pathology ; Female ; Humans ; Mammography ; Middle Aged ; Neoplasm Staging ; Sarcoma, Endometrial Stromal/diagnosis ; Sarcoma, Endometrial Stromal/pathology ; Ultrasonography, Mammary
    Language English
    Publishing date 2002-02-02
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-001-1294-x
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  7. Article: Male breast disease: clinical, mammographic, and ultrasonographic features.

    Günhan-Bilgen, Işil / Bozkaya, Halil / Ustün, Esin Emim / Memiş, Ayşenur

    European journal of radiology

    2002  Volume 43, Issue 3, Page(s) 246–255

    Abstract: Purpose: To describe and quantitate the radiological (mammographic and ultrasonographic) characteristics of male breast disease and to report the clinical and pathological findings.: Materials and methods: Two-hundred-thirty-six male patients with ... ...

    Abstract Purpose: To describe and quantitate the radiological (mammographic and ultrasonographic) characteristics of male breast disease and to report the clinical and pathological findings.
    Materials and methods: Two-hundred-thirty-six male patients with different male breast diseases, diagnosed at our institution between January 1990 and July 2001, were retrospectively evaluated. The history, physical examination, mammographic and ultrasonographic findings were analyzed.
    Results: The spectrum of the disease in 236 male patients were gynecomastia (n=206), primary breast carcinoma (n=14), fat necrosis (n=5), lipoma (n=3), subareolar abscess (n=2), epidermal inclusion cyst (n=1), sebaceous cyst (n=1), hematoma (n=1), myeloma (n=1), and metastatic carcinoma (n=2). The distribution of patterns of gynecomastia were; 34% (n=71) nodular, 35% (n=73) dendritic and 31% (n=62) diffuse glandular. Gynecomastia was unilateral in 55% (n=113) and bilateral in 45% (n=93) of the patients. Male breast cancer presented as a mass without microcalcifications in 86% (n=12) and with microcalcifications in 7% (n=1) of patients. The mass was obscured by gynecomastia, partially in two, totally in one patient. The location of the mass was retroareolar in 46% (n=6) and eccentric to the nipple in 54% (n=7) of patients. On ultrasonography (US), the contours were well-circumscribed in 20% (n=3) and irregular in 80% (n=12) of the masses.
    Conclusion: Male breast has a wide spectrum of diseases, some of which have characteristic radiological appearances that can be correlated with their pathologic diagnosis. In the evaluation of the male breast, mammography and US are essential and should be performed along with physical examination.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biopsy ; Breast Diseases/diagnosis ; Breast Diseases/diagnostic imaging ; Breast Diseases/pathology ; Diagnosis, Differential ; Humans ; Male ; Mammography ; Middle Aged ; Palpation ; Retrospective Studies ; Risk Factors ; Sensitivity and Specificity ; Ultrasonography, Mammary
    Language English
    Publishing date 2002-07-10
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/s0720-048x(01)00483-1
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  8. Article ; Online: Imaging characteristics of male breast disease.

    Adibelli, Zehra Hilal / Oztekin, Ozgur / Gunhan-Bilgen, Işil / Postaci, Hakan / Uslu, Adam / Ilhan, Enver

    The breast journal

    2010  Volume 16, Issue 5, Page(s) 510–518

    Abstract: The purpose of the study was to describe the imaging findings of male breast disease. One hundred and sixty-four male patients, who underwent mammography and ultrasonography (US) between January 1999 and December 2008, were retrospectively evaluated. ... ...

    Abstract The purpose of the study was to describe the imaging findings of male breast disease. One hundred and sixty-four male patients, who underwent mammography and ultrasonography (US) between January 1999 and December 2008, were retrospectively evaluated. Seventy-five patients (46%) underwent biopsy, and 89 patients (54%) were diagnosed radiologically. The radiologic and pathologic diagnoses in 164 cases of this series were 13 cancers (8%), including one ipsilateral and one contralateral breast cancers, 147 cases of gynecomastia (90%), one fibroadenoma (0.6%), two cases of fibrocystic disease of the breast (1.2%), and one epidermoid inclusion cyst (0.6%). Three mammographic patterns were adequate to describe all 147 cases of gynecomastia in our series: 53 patients (36%) had nodular gynecomastia, 46 patients (31%) had dendritic gynecomastia, and 48 patients (33%) had diffuse gynecomastia. Gynecomastia was unilateral in 65% of cases (n=95), and bilateral in 35% of cases (n=52). On physical examination, two of the malignant lesions had no clinic features of malignancy (15%). On mammography, 11 of 13 malignant masses were demonstrated (85%). A mass with microcalcifications was seen on mammograms in one case (9%). The contours of the masses were irregular in nine cases (82%), well-circumscribed in two cases (18%). The location of the masses was retroareolar in seven cases (64%) and eccentric to the nipple in four cases (36%). The size of the masses varied between 0.5 cm and 5 cm (mean 2.4 cm). Nipple retraction was evident in five cases (45%), and skin thickening in four cases (36%). All of the malignant masses were demonstrated on ultrasound; however, one of them was seen retrospectively after mammography. All of the masses were hypoechoic and solid, the contours were well-defined and smooth in two masses (15%), and irregular in 11 masses (85%), and five masses (39%) had posterior prominent shadowing. Axillary lymphadenopathia was detected in two cases (15%). One patient had a previous contralateral breast cancer, and one had an ipsilateral. On mammography, breast cancer characteristically exhibits an irregular subareolar mass, nipple retraction, and skin ulceration or thickening, but sometimes breast cancer has a well-circumscribed contour and punctuated microcalcifications. Ultrasonography is essential and useful for further characterization and helpful for demonstrating lymphadenopathies of the axillary region.
    MeSH term(s) Adult ; Breast Diseases/diagnostic imaging ; Breast Diseases/pathology ; Humans ; Male ; Mammography ; Middle Aged ; Retrospective Studies ; Ultrasonography, Mammary
    Language English
    Publishing date 2010-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1289960-4
    ISSN 1524-4741 ; 1075-122X
    ISSN (online) 1524-4741
    ISSN 1075-122X
    DOI 10.1111/j.1524-4741.2010.00951.x
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  9. Article: Neuroendocrine differentiated breast carcinoma: imaging features correlated with clinical and histopathological findings.

    Günhan-Bilgen, Isil / Zekioglu, Osman / Ustün, Esin Emin / Memis, Aysenur / Erhan, Yildiz

    European radiology

    2002  Volume 13, Issue 4, Page(s) 788–793

    Abstract: The aim of this study was to describe the imaging features of neuroendocrine differentiated breast carcinoma (NEDBC) and to correlate the radiological findings with the clinical and histopathological findings. A retrospective review of the mammograms of ... ...

    Abstract The aim of this study was to describe the imaging features of neuroendocrine differentiated breast carcinoma (NEDBC) and to correlate the radiological findings with the clinical and histopathological findings. A retrospective review of the mammograms of 1845 histopathologically proven breast cancer cases revealed five NEDBC. The clinical, imaging, and histopathological findings were analyzed. On mammography, a high-density mass was seen in all patients. The shape of the mass was round in 4 and irregular in 1 patient. The margins were spiculated in 2, indistinct in 1, microlobulated in 1, and partially obscured in 1 patient. On sonography, 4 patients had homogeneously hypoechoic masses with normal sound transmission. In 1 patient the mass was heterogeneously hypoechoic with mild posterior acoustic enhancement. The margins were microlobulated in 2, irregular in 2, and well-circumscribed in 1 patient. Neuroendocrine differentiated breast carcinoma should be included in the differential diagnosis of mammographically dense, round masses with predominantly spiculated or lobulated margins. Sonographically, they mostly present as irregular or microlobulated, homogeneously hypoechoic masses with normal sound transmission.
    MeSH term(s) Aged ; Breast/pathology ; Breast Neoplasms/diagnosis ; Carcinoma, Neuroendocrine/diagnosis ; Diagnosis, Differential ; Female ; Humans ; Magnetic Resonance Imaging ; Mammography ; Middle Aged ; Retrospective Studies ; Ultrasonography, Mammary
    Language English
    Publishing date 2002-08-14
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1085366-2
    ISSN 1432-1084 ; 0938-7994 ; 1613-3749
    ISSN (online) 1432-1084
    ISSN 0938-7994 ; 1613-3749
    DOI 10.1007/s00330-002-1567-z
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  10. Article: Invasive micropapillary carcinoma of the breast: clinical, mammographic, and sonographic findings with histopathologic correlation.

    Günhan-Bilgen, Isil / Zekioglu, Osman / Ustün, Esin Emin / Memis, Aysenur / Erhan, Yildiz

    AJR. American journal of roentgenology

    2002  Volume 179, Issue 4, Page(s) 927–931

    Abstract: Objective: The purpose of our study was to investigate the imaging features of invasive micropapillary carcinoma of the breast, which is a recently described, rare variant of infiltrating ductal carcinoma.: Conclusion: Invasive micropapillary ... ...

    Abstract Objective: The purpose of our study was to investigate the imaging features of invasive micropapillary carcinoma of the breast, which is a recently described, rare variant of infiltrating ductal carcinoma.
    Conclusion: Invasive micropapillary carcinoma of the breast usually manifests as a firm, immobile mass. Findings on mammography are of a spiculated, irregular or round, high density mass with or without associated microcalcifications. On sonography, the common findings are of a homogeneously hypoechoic, irregular or microlobulated mass with posterior acoustic shadowing or normal sound transmission. Axillary lymph nodes are frequently involved. Although these findings are not specific and may be seen with other breast malignancies, invasive micropapillary carcinoma should be included in the differential diagnosis for breast masses with these imaging features. Also, radiologic findings may help in the histopathologic differentiation of cases that are difficult to diagnose, such as metastatic tumors.
    MeSH term(s) Adult ; Aged ; Biopsy ; Breast Neoplasms/diagnosis ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/pathology ; Carcinoma, Ductal, Breast/diagnosis ; Carcinoma, Ductal, Breast/diagnostic imaging ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Papillary/diagnosis ; Carcinoma, Papillary/diagnostic imaging ; Carcinoma, Papillary/pathology ; Diagnosis, Differential ; Female ; Humans ; Mammography ; Middle Aged ; Neoplasm Invasiveness ; Ultrasonography, Mammary
    Language English
    Publishing date 2002-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82076-3
    ISSN 1546-3141 ; 0361-803X ; 0092-5381
    ISSN (online) 1546-3141
    ISSN 0361-803X ; 0092-5381
    DOI 10.2214/ajr.179.4.1790927
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