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  1. Article: [Status and associated factors of pre-exposure prophylaxis use among men who have sex with men in 24 cities in China].

    Pan, L / Xue, H / Yu, F / Shan, D / Zhang, D P / Wang, J J

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2023  Volume 44, Issue 6, Page(s) 905–911

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Male ; Homosexuality, Male ; Pre-Exposure Prophylaxis ; Cities ; Sexual and Gender Minorities ; Sexual Behavior ; China ; HIV Infections/prevention & control
    Language Chinese
    Publishing date 2023-06-28
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
    DOI 10.3760/cma.j.cn112338-20220831-00749
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Application and Inspiration of Information System used in National Health and Nutrition Examination Survey of America].

    Tu, J / He, H J / Hu, Y D / Pan, L / Shan, G L

    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi

    2022  Volume 43, Issue 7, Page(s) 1127–1133

    Abstract: The National Health and Nutrition Examination Survey (NHANES) of America has been running for more than 60 years and has achieved many significant achievements with international influence. The application of modern information technologies in NHANES ... ...

    Abstract The National Health and Nutrition Examination Survey (NHANES) of America has been running for more than 60 years and has achieved many significant achievements with international influence. The application of modern information technologies in NHANES provides a supplementary tool for the project's high quality and refined implementation. This paper introduces the information system of NHANES from seven aspects: project management, survey participant interview, physical examination, laboratory examination, field follow-up, data sharing, and social services. The construction and application prospects of the China National Health Survey Information System, suitable for China's native conditions, are also discussed in this article.
    MeSH term(s) China ; Humans ; Information Systems ; Nutrition Surveys ; Physical Examination ; Surveys and Questionnaires
    Language Chinese
    Publishing date 2022-07-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 645026-x
    ISSN 0254-6450
    ISSN 0254-6450
    DOI 10.3760/cma.j.cn112338-20211109-00871
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: From fighting COVID-19 pandemic to tackling sustainable development goals: An opportunity for responsible information systems research.

    Pan, Shan L / Zhang, Sixuan

    International journal of information management

    2020  Volume 55, Page(s) 102196

    Abstract: The recent outbreak of the COVID-19 pandemic has posed a significant threat to the healthy lives and well-being of billions of people worldwide. As the world begins to open up from lockdowns and enters an unprecedented state of vulnerability, or what ... ...

    Abstract The recent outbreak of the COVID-19 pandemic has posed a significant threat to the healthy lives and well-being of billions of people worldwide. As the world begins to open up from lockdowns and enters an unprecedented state of vulnerability, or what many have called "the new normal", it makes sense to reflect on what we have learned, revisit our fundamental assumptions, and start charting the way forward to contribute to building a sustainable world. In this essay, we argue that despite its significant damage to human lives and livelihoods, the coronavirus pandemic presents an excellent opportunity for the human family to act in solidarity and turn this crisis into an impetus to achieve the United Nation's (UN) Sustainable Development Goals (SDG). In this article, we will highlight the six relevant themes that have evolved during the pandemic and the corresponding topics that future researchers could focus on. We conclude by issuing a call for more research attention on tackling SDG through developing the concept and practice of digital sustainability.
    Keywords covid19
    Language English
    Publishing date 2020-07-06
    Publishing country Netherlands
    Document type Journal Article
    ISSN 0268-4012
    ISSN 0268-4012
    DOI 10.1016/j.ijinfomgt.2020.102196
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Fine mapping and candidate gene analysis of CaFCD1 affecting cuticle biosynthesis in Capsicum annuum L.

    Wang, Jin / Shan, Qingyun / Yi, Ting / Ma, Yanqing / Zhou, Xiaoxun / Pan, Luzhao / Miao, Wu / Zou, Xuexiao / Xiong, Cheng / Liu, Feng

    TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

    2023  Volume 136, Issue 3, Page(s) 46

    Abstract: Key message: CaFCD1 gene regulates pepper cuticle biosynthesis. Pepper (Capsicum annuum L.) is ...

    Abstract Key message: CaFCD1 gene regulates pepper cuticle biosynthesis. Pepper (Capsicum annuum L.) is an economically important vegetable crop that easily loses water after harvesting, which seriously affects the quality of its product. The cuticle is the lipid water-retaining layer on the outside of the fruit epidermis, which regulates the biological properties and reduces the rate of water-loss. However, the key genes involved in pepper fruit cuticle development are poorly understood. In this study, a pepper fruit cuticle development mutant fcd1 (fruit cuticle deficiency 1) was obtained by ethyl methanesulfonate mutagenesis. The mutant has great defects in fruit cuticle development, and the fruit water-loss rate of fcd1is significantly higher than that of the wild-type '8214' line. Genetic analysis suggested that the phenotype of the mutant fcd1 cuticle development defect was controlled by a recessive candidate gene CaFCD1 (Capsicum annuum fruit cuticle deficiency 1) on chromosome 12, which is mainly transcribed during fruit development. In fcd1, a base substitution within the CaFCD1 domain resulted in the premature termination of transcription, which affected cutin and wax biosynthesis in pepper fruit, as revealed by the GC-MS and RNA-seq analysis. Furthermore, the yeast one-hybrid and dual-luciferase reporter assays verified that the cutin synthesis protein CaCD2 was directly bound to the promoter of CaFCD1, suggesting that CaFCD1 may be a hub node in the cutin and wax biosynthetic regulatory network in pepper. This study provides a reference for candidate genes of cuticle synthesis and lays a foundation for breeding excellent pepper varieties.
    MeSH term(s) Capsicum/genetics ; Capsicum/metabolism ; Plant Breeding ; Phenotype ; Fruit/metabolism ; Water/metabolism ; Genetic Association Studies ; Gene Expression Regulation, Plant
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2023-03-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2170-2
    ISSN 1432-2242 ; 0040-5752
    ISSN (online) 1432-2242
    ISSN 0040-5752
    DOI 10.1007/s00122-023-04330-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: From fighting COVID-19 pandemic to tackling sustainable development goals

    Pan, Shan L. / Zhang, Sixuan

    International Journal of Information Management

    An opportunity for responsible information systems research

    2020  Volume 55, Page(s) 102196

    Keywords Computer Networks and Communications ; Library and Information Sciences ; Information Systems ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 0268-4012
    DOI 10.1016/j.ijinfomgt.2020.102196
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Optimizing the medical equipment investment in primary care centres in rural China: evidence from a panel threshold model.

    Xu, Wanchun / Pan, Zijing / Zhang, Liang / Lu, Shan

    BMC health services research

    2024  Volume 24, Issue 1, Page(s) 160

    Abstract: Background: The previous "one-size-fits-all" practice in resource allocation can no longer adapt to the spatial variation in population and health needs. This study aimed to investigate the spatially heterogeneous effect of medical equipment investment ... ...

    Abstract Background: The previous "one-size-fits-all" practice in resource allocation can no longer adapt to the spatial variation in population and health needs. This study aimed to investigate the spatially heterogeneous effect of medical equipment investment in the township health centres in rural China to optimize the investment strategies.
    Methods: Based on the national-scale stratified multistage cluster sampling, 319 township health centres from six provinces were included in the study. The retrospective data from 2013 to 2017 were collected for each sampled township health centres and the corresponding township community. The panel threshold regression model was applied to estimate the nonlinear effect of medical equipment increment on the service utilization due to the township communities' urbanization degree. The influence of township community remoteness on the effects of equipment increment was investigated through subgroup analysis.
    Results: Among the township health centres in the neighbouring towns of the county seat (travel time to the county seat < 1 h), the significant effect of medical equipment increment was only found in the township health centres of the towns with high urbanization degrees (the proportion of the residents living in the built-up area > 69.89%), of which the effect size was 774.81 (95% CI 495.63, 1053.98, p < 0.05). Among the township health centres in the remote towns (travel time ≥ 1 h), the effect of medical equipment increment in the township health centres of the low urbanized towns (urban ≤ 5.99%, β = 1052.54, p < 0.01) was around four times the size of that of the counterparts (urban > 5.99%, β = 237.00, p < 0.01).
    Conclusion: This study demonstrated the spatially heterogeneous effect of medical equipment investment in the primary care centres in rural China. The priority of the equipment investment was suggested to be given to the township health centres in the remote towns with a low urbanization degree and those in the highly-urbanized neighbouring towns of the county seats.
    MeSH term(s) Humans ; Retrospective Studies ; China/epidemiology ; Rural Population ; Urbanization ; Primary Health Care
    Language English
    Publishing date 2024-02-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050434-2
    ISSN 1472-6963 ; 1472-6963
    ISSN (online) 1472-6963
    ISSN 1472-6963
    DOI 10.1186/s12913-024-10596-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: HER catalytic activity and regulation of a transition metal atom-anchored BC

    Pan, Liying / Kang, Xuxin / Gao, Shan / Duan, Xiangmei

    Physical chemistry chemical physics : PCCP

    2024  Volume 26, Issue 2, Page(s) 1011–1016

    Abstract: An atomic-level understanding of the hydrogen evolution reaction (HER) on a transition metal (TM) atom-anchored 2D monolayer is vital to explore highly efficient catalysts for hydrogen production. Here, the catalytic activities and modulation of TM atom ( ...

    Abstract An atomic-level understanding of the hydrogen evolution reaction (HER) on a transition metal (TM) atom-anchored 2D monolayer is vital to explore highly efficient catalysts for hydrogen production. Here, the catalytic activities and modulation of TM atom (Ti, Fe, Cu, Zn, Mo, Ag, Au)-doped BC
    Language English
    Publishing date 2024-01-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp04660e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Rational design and synthesis of 2,4-dichloro-6-methyl pyrimidine derivatives as potential selective EGFR

    Duan, Lei / Chu, Cilong / Huang, Xiaoling / Yao, Huizhi / Wen, Jie / Chen, Rui / Wang, Caolin / Tu, Yuanbiao / Lv, Qiaoli / Pan, Qingshan / Xu, Shan

    Archiv der Pharmazie

    2024  , Page(s) e2300736

    Abstract: ... inhibitors of the EGFR kinase. The most promising compound, L-18, showed better inhibitory activity (81.9 ...

    Abstract Many patients with non-small cell lung cancer (NSCLC) initially benefit from epidermal growth factor receptor (EGFR) targeted therapy. Unfortunately, varying degrees of resistance or side effects eventually develop. Overcoming and preventing the resistance and side effects of EGFR inhibitors has become a hot topic of research today. Based on the previous studies on AZD-9291, we designed and synthesized two series of 2,4-dichloro-6-methylpyrimidine derivatives, 19 compounds in total, as potential inhibitors of the EGFR kinase. The most promising compound, L-18, showed better inhibitory activity (81.9%) and selectivity against EGFR
    Language English
    Publishing date 2024-02-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 6381-2
    ISSN 1521-4184 ; 0365-6233 ; 1437-1014
    ISSN (online) 1521-4184
    ISSN 0365-6233 ; 1437-1014
    DOI 10.1002/ardp.202300736
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Nanomaterial-based magnetic surface molecularly imprinted polymers for specific extraction and efficient recognition of dibutyl phthalate.

    Wang, Shan / Yang, Jingying / Sun, Jiaqing / Liu, Kaixin / Xie, Xiaoqian / Hong, Liping / Wang, Shuo / Pan, Mingfei

    Food chemistry

    2023  Volume 426, Page(s) 136621

    Abstract: ... combined with GC-MS method showed good linearity in DBP concentration range of 0.02-1.0 mg L ...

    Abstract A rapid and selective sorbent for the enrichment of dibutyl phthalate (DBP) from water and Chinese Baijiu samples was established using magnetic surface molecularly imprinted polymers (MSMIPs) combined with gas chromatography-mass spectrometer (GC-MS). The MSMIPs were synthesized using a magnetic nanosphere material with silica layer, increasing the polymer surface area as a carrier. Compared with the traditional methods, the addition of magnetic microspheres simplified the process of food substrate purification and significantly shortened the pre-concentration time. The MSMIPs adsorption conforms to the Freundlich isotherm model as multilayer adsorption on an inhomogeneous surface and the pseudo-second-order model. The developed MSMIPs combined with GC-MS method showed good linearity in DBP concentration range of 0.02-1.0 mg L
    MeSH term(s) Dibutyl Phthalate ; Molecularly Imprinted Polymers ; Molecular Imprinting/methods ; Nanostructures ; Adsorption ; Magnetic Phenomena ; Solid Phase Extraction/methods
    Chemical Substances Dibutyl Phthalate (2286E5R2KE) ; Molecularly Imprinted Polymers
    Language English
    Publishing date 2023-06-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2023.136621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Information resource orchestration during the COVID-19 pandemic: A study of community lockdowns in China.

    Pan, Shan L / Cui, Miao / Qian, Jinfang

    International journal of information management

    2020  Volume 54, Page(s) 102143

    Abstract: The outbreak of the COVID-19 pandemic has created significant challenges for people worldwide. To combat the virus, one of the most dramatic measures was the lockdown of 4 billion people in what is believed to be the largest quasi-quarantine in human ... ...

    Abstract The outbreak of the COVID-19 pandemic has created significant challenges for people worldwide. To combat the virus, one of the most dramatic measures was the lockdown of 4 billion people in what is believed to be the largest quasi-quarantine in human history. As a response to the call to study information behavior during a global health crisis, we adopted a resource orchestration perspective to investigate six Chinese families who survived the lockdown. We explored how elderly, young and middle-aged individuals and children resourced information and how they adapted their information behavior to emerging online technologies. Two information resource orchestration practices (information resourcing activities and information behavior adaptation activities) and three mechanisms (online emergence and convergence in community resilience, the overcoming of information flow impediments, and the application of absorptive capacity) were identified in the study.
    Keywords covid19
    Language English
    Publishing date 2020-05-11
    Publishing country Netherlands
    Document type Case Reports
    ISSN 0268-4012
    ISSN 0268-4012
    DOI 10.1016/j.ijinfomgt.2020.102143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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