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  1. Article ; Online: Configuration of Aerosol Delivery Devices and Their Placement: Let's Be Sure We're Paying Attention to the Literature.

    Op't Holt, Timothy B

    Respiratory care

    2016  Volume 61, Issue 3, Page(s) 389

    MeSH term(s) Aerosols ; Attention ; Humans ; Salaries and Fringe Benefits
    Chemical Substances Aerosols
    Language English
    Publishing date 2016-03
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.04699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Intratracheal albuterol: a potential intervention for the asthma toolbox.

    Op't Holt, Timothy B

    Respiratory care

    2015  Volume 60, Issue 5, Page(s) 756

    MeSH term(s) Albuterol/administration & dosage ; Bronchoalveolar Lavage/methods ; Bronchoconstriction/drug effects ; Bronchodilator Agents/administration & dosage ; Female ; Humans ; Male ; Respiratory Insufficiency/drug therapy
    Chemical Substances Bronchodilator Agents ; Albuterol (QF8SVZ843E)
    Language English
    Publishing date 2015-05
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.04202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Additional evidence to support the use of noninvasive ventilation in asthma exacerbation.

    Op't Holt, Timothy B

    Respiratory care

    2013  Volume 58, Issue 2, Page(s) 380–382

    MeSH term(s) Adrenergic beta-Agonists/administration & dosage ; Asthma/physiopathology ; Asthma/therapy ; Bronchodilator Agents/administration & dosage ; Continuous Positive Airway Pressure ; Female ; Humans ; Male ; Radiopharmaceuticals ; Technetium Tc 99m Pentetate
    Chemical Substances Adrenergic beta-Agonists ; Bronchodilator Agents ; Radiopharmaceuticals ; Technetium Tc 99m Pentetate (VW78417PU1)
    Language English
    Publishing date 2013-02
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.02314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Assessment-based respiratory care

    Op'T Holt, Timothy B.

    1986  

    Author's details Timothy B. Op't Holt
    Keywords Respiratory Therapy ; Respiratory Tract Diseases / therapy
    Size XIV, 265 S. : Ill., graph. Darst.
    Publisher Wiley
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT002965939
    ISBN 0-471-80965-9 ; 978-0-471-80965-4
    Database Catalogue ZB MED Medicine, Health

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  5. Article: E-mail communication in a smoking-cessation program.

    Op't Holt, Timothy B

    Respiratory care

    2009  Volume 54, Issue 8, Page(s) 1024–1025

    MeSH term(s) Directive Counseling ; Electronic Mail ; Female ; Humans ; Male ; Smoking Cessation/methods
    Language English
    Publishing date 2009-08
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 603252-7
    ISSN 0020-1324 ; 0098-9142
    ISSN 0020-1324 ; 0098-9142
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Inhaled beta agonists.

    Op't Holt, Timothy B

    Respiratory care

    2007  Volume 52, Issue 7, Page(s) 820–832

    Abstract: The beta(2) adrenoreceptor is a large molecule of some 413 amino acids. The duration of stimulation of this receptor depends on where and for how long a beta(2) adrenergic drug attaches itself to the beta(2) adrenoreceptor. beta(2) adrenergic drugs have ... ...

    Abstract The beta(2) adrenoreceptor is a large molecule of some 413 amino acids. The duration of stimulation of this receptor depends on where and for how long a beta(2) adrenergic drug attaches itself to the beta(2) adrenoreceptor. beta(2) adrenergic drugs have been used for over 5,000 years, but only recently have we had the advantage of adrenergic drugs specific to the beta(2) adrenoreceptor. The short-acting beta(2) adrenergic drugs most frequently used include albuterol, pirbuterol, and levalbuterol. Levalbuterol, the R enantiomer of albuterol, has been described by some as a more effective bronchodilator than racemic albuterol, because it contains none of the S enantiomer. Some contend that the S isomer has pro-inflammatory properties. The 2 long-acting beta(2) adrenergic drugs are salmeterol and formoterol. These drugs have a duration of 12 h and reportedly improve forced expiratory volume in the first second, quality of life, and symptoms. Some recent reports indicate that these drugs are associated with higher mortality, but several authors have registered the opinion that it is not the bronchodilator that should be questioned, but instead that the fault lies in the patient recruitment in those studies. Regardless, if these long-acting drugs are effective for a given patient, it would seem inadvisable to withdraw them, given the current state of evidence. Arformoterol tartrate, the R enantiomer of formoterol, was approved by the U.S. Food and Drug Administration in October 2006; it is available as a nebulizer solution, to be administered every 12 h. Several other long-acting R isomers and RR isomers are in the approval pipeline.
    MeSH term(s) Administration, Inhalation ; Adrenergic beta-Agonists/administration & dosage ; Adrenergic beta-Agonists/chemistry ; Adrenergic beta-Agonists/pharmacokinetics ; Bronchodilator Agents/administration & dosage ; Bronchodilator Agents/chemistry ; Bronchodilator Agents/pharmacokinetics ; Humans ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Receptors, Adrenergic, beta-2/administration & dosage ; Receptors, Adrenergic, beta-2/chemistry ; United States
    Chemical Substances Adrenergic beta-Agonists ; Bronchodilator Agents ; Receptors, Adrenergic, beta-2
    Language English
    Publishing date 2007-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 603252-7
    ISSN 0020-1324 ; 0098-9142
    ISSN 0020-1324 ; 0098-9142
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Problem-based and case-based learning in respiratory care education.

    Op't Holt, Timothy B

    Respiratory care clinics of North America

    2005  Volume 11, Issue 3, Page(s) 489–504

    Abstract: Problem-based learning has been used in respiratory therapy education for a relatively short time. The purpose of PBL is to produce a graduate who has improved critical thinking and life-long learning skills. On a practical note, another goal is to help ... ...

    Abstract Problem-based learning has been used in respiratory therapy education for a relatively short time. The purpose of PBL is to produce a graduate who has improved critical thinking and life-long learning skills. On a practical note, another goal is to help the graduate pass the NBRC Clinical Simulation examination. PBL is the use of cases to provide a stimulus for the specification of learning issues, or objectives, which the students research and discuss. The heart of the PBL process is the tutorial group, composed ofa group of five to seven students and a faculty facilitator. Students work through the case, listing facts, testing hypotheses, learning pharmacology,and studying the learning issues of the case. Information is learned in thecontext of the patient case, rather than in isolated classes. Cases are presented in the progressive-disclosure model. Student evaluation consists of written examinations, self- and peer evaluation, and with an independent case study process. Program evaluation has shown that students enjoy the process and think that they are performing clinically better than their non-PBL peers. Pass rates for the Clinical Simulation examination are above the national average. A more in-depth study of program outcomes is indicated.
    MeSH term(s) Allied Health Personnel/education ; Educational Measurement/methods ; Educational Measurement/standards ; Humans ; Mentors/education ; Problem-Based Learning/methods ; Respiratory Therapy/education ; Students, Health Occupations ; Teaching/methods ; Teaching/standards ; Thinking
    Language English
    Publishing date 2005-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1384525-1
    ISSN 1078-5337
    ISSN 1078-5337
    DOI 10.1016/j.rcc.2005.04.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book: Assessment-based respiratory care

    Op't Holt, Timothy B

    (Wiley medical publication)

    1986  

    Title variant Assessment based respiratory care
    Author's details Timothy B. Op't Holt
    Series title Wiley medical publication
    MeSH term(s) Respiratory Therapy ; Respiratory Tract Diseases/diagnosis ; Respiratory Tract Diseases/therapy
    Language English
    Size xiv, 265 p. :, ill.
    Publisher Wiley
    Publishing place New York
    Document type Book
    Note Cover and spine title: Assessment based respiratory care.
    ISBN 9780471809654 ; 0471809659
    Database Catalogue of the US National Library of Medicine (NLM)

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