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Article: Electrochromic detection of a coherent component in the formation of the charge pair P(+)H(L)(-) in bacterial reaction centers.

Vos, M H / Rischel, C / Jones, M R / Martin, J L

2000 Volume 39, Issue 29, Page(s) 8353–8361

Abstract: ... motions. The kinetics of charge separation toward the radical pair state P(+)H(L)(-) were studied ... reported absolute absorption spectrum of the P(+)H(L)(-) state is discussed in terms of this shift. In wild ...

Abstract	We demonstrate coupling of an intraprotein electron transfer reaction to coherent vibrational motions. The kinetics of charge separation toward the radical pair state P(+)H(L)(-) were studied in reaction centers of Rhodobacter sphaeroides at 15 K. The electrochromic shift of the bacteriochlorophyll monomers is the most prominent spectral feature associated with this charge displacement. The newly reported absolute absorption spectrum of the P(+)H(L)(-) state is discussed in terms of this shift. In wild-type reaction centers, the rise kinetics of the electrochromic shift display a small but significant 30 cm(-)(1) periodic modulation (period of approximately 1 ps). This modulation is also present in FL181Y mutant reaction centers, where overall charge separation is somewhat more rapid than in the wild-type reaction center. In contrast, in YM210L mutant reaction centers, where the charge separation is much slower, the modulation is absent. The conclusion that the motion along the reaction coordinate has a 30 cm(-)(1) coherent component is discussed in light of possible mechanisms of electron transfer.
MeSH term(s)	Electrochemistry ; Electron Transport ; Kinetics ; Light-Harvesting Protein Complexes ; Mutation ; Photosynthetic Reaction Center Complex Proteins/chemistry ; Photosynthetic Reaction Center Complex Proteins/genetics ; Photosynthetic Reaction Center Complex Proteins/metabolism ; Rhodobacter sphaeroides/genetics ; Rhodobacter sphaeroides/metabolism ; Spectrophotometry, Infrared
Chemical Substances	Light-Harvesting Protein Complexes ; Photosynthetic Reaction Center Complex Proteins
Language	English
Publishing date	2000-07-25
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1108-3
ISSN	1520-4995 ; 0006-2960
ISSN (online)	1520-4995
ISSN	0006-2960
DOI	10.1021/bi000759n
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Article: Safety and Feasibility of the BYCROSS

van Leeuwen, Goudje L / Bokkers, Reinoud P H / Oldenziel, Job / Schuurmann, Richte C L / Vos, Cornelis G / de Vries, Jean-Paul P M

Journal of clinical medicine

2024 Volume 13, Issue 6

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2024-03-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm13061809
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Article ; Online: Association between days post conception and lactation persistency in dairy cattle.

Chen, Y / Steeneveld, W / Frankena, K / Leemans, I / Aardema, H / Vos, P L A M / Nielen, M / Hostens, M

Journal of dairy science

2024

Abstract: Determining the optimal insemination moment for individual cows is complex, particularly when considering the impact of pregnancy on milk production. The effect of pregnancy on the absolute milk yield has already been reported in several studies. ... ...

Abstract	Determining the optimal insemination moment for individual cows is complex, particularly when considering the impact of pregnancy on milk production. The effect of pregnancy on the absolute milk yield has already been reported in several studies. Currently, there is limited quantitative knowledge about the association between days post conception (DPC) and lactation persistency, based on a lactation curve model, and, specifically, how persistency changes during pregnancy and relates to the days in milk at conception (DIMc). Understanding this association might provide valuable insights to determine the optimal insemination moment. This study, therefore, aimed to investigate the association between DPC and lactation persistency, with an additional focus on the influence of DIMc. Available milk production data from 2005 to 2022 were available for 23,908 cows from 87 herds located throughout the Netherlands and Belgium. Persistency was measured by a lactation curve characteristic decay, representing the time taken to halve milk production after peak yield. Decay was calculated for 8 DPC (0, 30, 60, 90, 120, 150, 180 and 210 d after DIMc) and served as the dependent variable. Independent variables included DPC, DIMc (< = 60, 61-90, 91-120, 121-150, 151-180, 181-210, > 210), parity group, DPC × parity group, DPC × DIMc and variables from 30 d before DIMc as covariates. The results showed an increase in decay, i.e., a decrease in persistency, during pregnancy for both parity groups, albeit in different ways. Specifically, from DPC 150 to DPC 210, multiparous cows showed a higher decline in persistency compared with primiparous cows. Furthermore, a later DIMc (cows conceiving later) was associated with higher persistency. Except for the early DIMc groups (DIMc < 90), DIMc does not impact the change in persistency by gestation. The findings from this study contribute to a better understanding of how DPC and DIMc during lactation influence lactation persistency, enabling more informed decision-making by farmers who wish to take persistency into account in their reproduction management.
Language	English
Publishing date	2024-04-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	242499-x
ISSN	1525-3198 ; 0022-0302
ISSN (online)	1525-3198
ISSN	0022-0302
DOI	10.3168/jds.2023-24282
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Article ; Online: Presence of digestible starch impacts

Klostermann, Cynthia E / Endika, Martha F / Kouzounis, Dimitrios / Buwalda, Piet L / de Vos, Paul / Zoetendal, Erwin G / Bitter, Johannes H / Schols, Henk A

Food & function

2024 Volume 15, Issue 1, Page(s) 223–235

Abstract: Starch is an important energy source for humans. Starch escaping digestion in the small intestine will transit to the colon to be fermented by gut microbes. Many gut microbes express α-amylases that can degrade soluble starch, but only a few are able to ... ...

Abstract	Starch is an important energy source for humans. Starch escaping digestion in the small intestine will transit to the colon to be fermented by gut microbes. Many gut microbes express α-amylases that can degrade soluble starch, but only a few are able to degrade intrinsic resistant starch (RS), which is insoluble and highly resistant to digestion (≥80% RS). We studied the
MeSH term(s)	Infant ; Adult ; Humans ; Resistant Starch/metabolism ; Fermentation ; Starch/metabolism ; Feces/microbiology ; Acetates ; Digestion
Chemical Substances	Resistant Starch ; Starch (9005-25-8) ; Acetates
Language	English
Publishing date	2024-01-02
Publishing country	England
Document type	Journal Article
ZDB-ID	2612033-1
ISSN	2042-650X ; 2042-6496
ISSN (online)	2042-650X
ISSN	2042-6496
DOI	10.1039/d3fo01763j
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Article ; Online: Efficacy of Walking Adaptability Training on Walking Capacity in Ambulatory People With Motor Incomplete Spinal Cord Injury: A Multicenter Pragmatic Randomized Controlled Trial.

Zwijgers, Eline / van Dijsseldonk, Rosanne B / Vos-van der Hulst, Marije / Hijmans, Juha M / Geurts, Alexander C H / Keijsers, Noël L W

Neurorehabilitation and neural repair

2024 , Page(s) 15459683241248088

Abstract: Background and objective: Balance and walking capacity are often impaired in people with motor incomplete spinal cord injury (iSCI), frequently resulting in reduced functional ambulation and participation. This study aimed to assess the efficacy of ... ...

Abstract	Background and objective: Balance and walking capacity are often impaired in people with motor incomplete spinal cord injury (iSCI), frequently resulting in reduced functional ambulation and participation. This study aimed to assess the efficacy of walking adaptability training compared to similarly dosed conventional locomotor and strength training for improving walking capacity, functional ambulation, balance confidence, and participation in ambulatory people with iSCI. Methods: We conducted a 2-center, parallel-group, pragmatic randomized controlled trial. Forty-one people with iSCI were randomized to 6 weeks of (i) walking adaptability training (11 hours of Gait Real-time Analysis Interactive Lab (GRAIL) training-a treadmill in a virtual reality environment) or (ii) conventional locomotor and strength training (11 hours of treadmill training and lower-body strength exercises). The primary measure of walking capacity was maximal walking speed, measured with an overground 2-minute walk test. Secondary outcome measures included the Spinal Cord Injury Functional Ambulation Profile (SCI-FAP), the Activities-specific Balance Confidence (ABC) scale, and the Utrecht Scale for Evaluation of Rehabilitation-Participation (USER-P). Results: No significant difference in maximal walking speed between the walking adaptability (n = 17) and conventional locomotor and strength (n = 18) training groups was found 6 weeks after training at follow-up (-0.05 m/s; 95% CI = -0.12-0.03). In addition, no significant group differences in secondary outcomes were found. However, independent of intervention, significant improvements over time were found for maximal walking speed, SCI-FAP, ABC, and USER-P restrictions scores. Trial registration: Dutch Trial Register; Effect of GRAIL training in iSCI.
Language	English
Publishing date	2024-04-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491637-x
ISSN	1552-6844 ; 1545-9683 ; 0888-4390
ISSN (online)	1552-6844
ISSN	1545-9683 ; 0888-4390
DOI	10.1177/15459683241248088
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Article ; Online: HPV-specific antibodies in female genital tract secretions captured via first-void urine retain their neutralizing capacity.

Téblick, Laura / Lipovac, Marijana / Molenberghs, Freya / Delputte, Peter / De Vos, Winnok H / Vorsters, Alex

Human vaccines & immunotherapeutics

2024 Volume 20, Issue 1, Page(s) 2330168

Abstract: Human papillomavirus (HPV) vaccines, primarily relying on neutralizing antibodies, have proven highly effective. Recently, HPV-specific antibodies have been detected in the female genital tract secretions captured by first-void urine (FVU), offering a ... ...

Abstract	Human papillomavirus (HPV) vaccines, primarily relying on neutralizing antibodies, have proven highly effective. Recently, HPV-specific antibodies have been detected in the female genital tract secretions captured by first-void urine (FVU), offering a minimally invasive diagnostic approach. In this study, we investigated whether HPV16-specific antibodies present in FVU samples retain their neutralizing capacity by using pseudovirion-based neutralization assays. Paired FVU and serum samples (vaccinated
MeSH term(s)	Humans ; Female ; Adolescent ; Young Adult ; Adult ; Papillomavirus Infections/prevention & control ; Reproducibility of Results ; Antibodies, Viral ; Antibodies, Neutralizing ; Papillomavirus Vaccines ; Neutralization Tests/methods ; Genitalia, Female ; Human papillomavirus 16 ; Immunoglobulin G
Chemical Substances	Antibodies, Viral ; Antibodies, Neutralizing ; Papillomavirus Vaccines ; Immunoglobulin G
Language	English
Publishing date	2024-04-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2664176-8
ISSN	2164-554X ; 2164-5515
ISSN (online)	2164-554X
ISSN	2164-5515
DOI	10.1080/21645515.2024.2330168
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Zs.A 6967: Show issues

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Article ; Conference proceedings: Cellular Components in Whole Blood Contribute to the Development of Thromboembolic Events in Patients with Pancreatic Cancer

Willems, R. A.L. / Roest, M. / de Vos-Geelen, J. / de Laat, B. / ten Cate, H.

Hämostaseologie

2024 Volume 44, Issue S 01

Event/congress	GTH Congress 2024 - 68th Annual Meeting of the Society of Thrombosis and Haemostasis Research - Building Bridges in Coagulation, Vienna, Austria, 2024-03-27
Language	English
Publishing date	2024-02-01
Publisher	Georg Thieme Verlag
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	801512-0
ISSN	2567-5761 ; 0720-9355
ISSN (online)	2567-5761
ISSN	0720-9355
DOI	10.1055/s-0044-1779099
Database	Thieme publisher's database

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Zs.A 1631: Show issues

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Article ; Online: A 10-year follow-up of reproductive outcomes in women attempting motherhood after elective oocyte cryopreservation.

Loreti, S / Darici, E / Nekkebroeck, J / Drakopoulos, P / Van Landuyt, L / De Munck, N / Tournaye, H / De Vos, M

Human reproduction (Oxford, England)

2023 Volume 39, Issue 2, Page(s) 355–363

Abstract: Study question: Which reproductive treatment outcomes are observed in women who underwent elective oocyte cryopreservation (EOC) and who returned to the clinic with a desire for a child?: Summary answer: Whether to warm oocytes or to first use fresh ... ...

Abstract	Study question: Which reproductive treatment outcomes are observed in women who underwent elective oocyte cryopreservation (EOC) and who returned to the clinic with a desire for a child? Summary answer: Whether to warm oocytes or to first use fresh own oocytes for ART depends on age upon returning, but both strategies result in favorable reproductive outcomes. What is known already: Most affluent countries have observed a trend toward postponement of childbearing, and EOC is increasingly used based on the assumption that oocytes cryopreserved at a younger age may extend a woman's reproductive lifespan and mitigate her age-related fertility decline. Although most follow-up studies after EOC have focused on women who requested oocyte warming, a substantial proportion of women who do not conceive naturally will embark on fertility treatment without using their cryopreserved oocytes. Reports on reproductive outcomes in past EOC users are scarce, and the lack of reproductive treatment algorithms in this group of women hampers counseling toward the most efficient clinical strategy. Study design, size, duration: This retrospective observational single-center study encompasses 843 women who had elective oocyte vitrification between 2009 and 2019 at our fertility clinic. Women who underwent fertility preservation for medical or oncological reasons were excluded. This study describes the outcomes of the diverse reproductive treatment strategies performed until May 2022 in women returning to our clinic to attempt motherhood. Participants/materials, setting, methods: Using descriptive statistics, patient characteristics and data of ovarian stimulation (OS) of EOC cycles were analyzed, as well as data related to OS and laboratory data of ART in women who pursued fertility treatment with and/or without using their cryopreserved oocytes. The primary outcome was live birth rate (LBR) per patient after oocyte warming and after ART using fresh oocytes. Secondary outcomes were return rate, utilization rate of the cryopreserved oocytes, laboratory outcomes upon return, and LBR per embryo transfer. A multivariable regression model was developed to identify factors associated with the decision to thaw oocytes as the primary strategy and factors associated with ongoing pregnancy upon return to the clinic. Main results and the role of chance: A total of 1353 EOC cycles (mean ± SD, 1.6 ± 0.9 per patient) were performed. At the time of EOC, the mean age was 36.5 ± 2.8 years, mean anti-Müllerian hormone (AMH) was 2.3 ± 2.0 ng/ml, and 174 (20.6%) women had a partner. On average, 13.9 ± 9.2 mature oocytes were cryopreserved. Two hundred thirty-one (27.4%) women returned to the clinic, an average of 39.9 ± 23.4 months after EOC. Upon returning, their mean age was 40.4 ± 3.1 years, mean AMH was 1.5 ± 1.5 ng/ml, and 158/231 (68.3%) patients had a partner. As a primary approach, 110/231 (47.6%) past EOC users embarked on oocyte warming, 50/231 (21.6%) had intrauterine insemination, and 71/231 (30.7%) had ART using fresh own oocytes. Cumulative LBR (CLBR) was 45.9% (106/231) notwithstanding a miscarriage rate (MR) of 30.7% (51/166) in the entire cohort. In total, 141 women performed oocyte warming at some stage in their treatment trajectory. A subset of 90/231 (39.0%) patients exclusively had oocyte warming (41.6 ± 3.0 years, with 10.0 ± 5.2 oocytes warmed per patient). 52/231 (22.5%) patients exclusively had ART using fresh own oocytes (mean age of 39.0 ± 2.8 years, with 9.9 ± 7.4 mature oocytes retrieved per patient). CLBR was 37/90 (41.1%) in the oocyte warming-only group and 25/52 (48.1%) in the OS-only group. MR/transfer was 25.0% and 29.3% in the oocyte warming-only group and the OS-only group, respectively. Limitations, reasons for caution: Both sample size and the retrospective design are limitations of this study. The decision to embark on a specific reproductive treatment strategy was based on patient preference, after counseling on their treatment options. This precludes direct comparison of the efficiency of reproductive treatment options in past EOC users in this study. Wider implications of the findings: Reporting on clinical outcomes of women who underwent EOC and returned to the clinic to embark on divergent reproductive treatment strategies is mandatory to establish guidelines for best clinical practice in this growing patient population. Study funding/competing interest(s): None. Trial registration number: N/A.
MeSH term(s)	Humans ; Pregnancy ; Child ; Female ; Adult ; Male ; Follow-Up Studies ; Oocyte Retrieval ; Retrospective Studies ; Cryopreservation ; Oocytes ; Live Birth/epidemiology ; Pregnancy Rate
Language	English
Publishing date	2023-12-23
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	632776-x
ISSN	1460-2350 ; 0268-1161 ; 1477-741X
ISSN (online)	1460-2350
ISSN	0268-1161 ; 1477-741X
DOI	10.1093/humrep/dead267
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Article ; Online: Reply: Further Insights Into the Prognostic Value of Left Atrial Strain in Dilated Cardiomyopathy?

Raafs, Anne G / Henkens, Michiel T H M / Vos, Jacqueline L / Nijveldt, Robin / Verdonschot, Job A J

JACC. Cardiovascular imaging

2022 Volume 15, Issue 12, Page(s) 2156–2157

MeSH term(s)	Humans ; Cardiomyopathy, Dilated/diagnostic imaging ; Prognosis ; Atrial Fibrillation ; Predictive Value of Tests ; Atrial Appendage
Language	English
Publishing date	2022-11-16
Publishing country	United States
Document type	Letter
ZDB-ID	2491503-8
ISSN	1876-7591 ; 1936-878X
ISSN (online)	1876-7591
ISSN	1936-878X
DOI	10.1016/j.jcmg.2022.09.017
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Article ; Online: ASO Author Reflections: Colonoscopic-Assisted Laparoscopic Wedge Resection Seems a Valuable Addition to the Current Local Resection Techniques in Case of Suspected Deep-Invasive T1 Colon Cancer.

Hanevelt, Julia / Moons, Leon M G / de Vos Tot Nederveen Cappel, Wouter H / van Westreenen, Henderik L

Annals of surgical oncology

2023 Volume 30, Issue 4, Page(s) 2066–2067

MeSH term(s)	Humans ; Colonic Neoplasms/surgery ; Colonoscopy/methods ; Laparoscopy/methods
Language	English
Publishing date	2023-01-04
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	1200469-8
ISSN	1534-4681 ; 1068-9265
ISSN (online)	1534-4681
ISSN	1068-9265
DOI	10.1245/s10434-022-13051-5
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