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  1. Article: Three new 2-(2-phenylethyl)chromones from ‘Chong-lou’ agarwood of Aquilaria sinensis

    Su, Xin / Cai, Cai-Hong / Dong, Wen-Hua / Gai, Cui-Juan / Wang, Ya-Li / Mei, Wen-Li / Xu, Xing-Lian / Dai, Hao-Fu / Chen, Hui-Qin

    Phytochemical Society of Europe Phytochemistry letters. 2022 Oct., v. 51

    2022  

    Abstract: ... isolated from ‘Chong-lou’ agarwood originating from Aquilaria sinensis for the first time. Their new ...

    Abstract Three new 2-(2-phenylethyl)chromones (1, 2 and 3), together with four known analogues 4~7 were isolated from ‘Chong-lou’ agarwood originating from Aquilaria sinensis for the first time. Their new structures were elucidated on the basis of spectroscopic techniques (UV, IR, MS, 1D and 2D NMR), as well as by comparison with the literature data. Compounds 6 and 7 exhibited significant cytotoxicity against human cancer cell line K562 with IC₅₀ values of 19.79 ± 0.03 and 21.39 ± 0.05 μM, respectively.
    Keywords Aquilaria sinensis ; cytotoxicity ; humans ; neoplasm cells ; plant biochemistry
    Language English
    Dates of publication 2022-10
    Size p. 86-90.
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 1874-3900
    DOI 10.1016/j.phytol.2022.07.009
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Bu Shen Tiao Chong recipe restores diminished ovary reserve through the BDNF pathway.

    Xia, Tian / Fu, Yu / Li, Shuang / Ma, Ruihong / Zhao, Zhimei / Wang, Baojuan / Chao, Chune

    Journal of assisted reproduction and genetics

    2016  Volume 33, Issue 6, Page(s) 795–805

    Abstract: ... Chong recipe) in retrieving diminished ovary reserve (DOR).: Methods: The DOR model was established ...

    Abstract Purpose: The purpose of this study was to explore the molecular pathway of BSTCR (Bu Shen Tiao Chong recipe) in retrieving diminished ovary reserve (DOR).
    Methods: The DOR model was established through injecting cyclophosphamide and the effect of BSTCR was examined under this background.
    Results: BSTCR was shown to restore depleted brain-derived neurotrophic factor (BDNF), CDC2, cyclin B, GSH1, and P38 levels as well as impaired oocyte maturation and the higher apoptosis induced in DOR. BSTCR also enhances the response of oocytes to in vitro fertilization, with higher implantation rate, birth rate, and placenta weight.
    Conclusion: BSTCR might exert its beneficial role in oocyte maturation and restore DOR through regulating the BDNF pathway. And this pathway itself is probably through the consequence on several serum hormones such as FSH, E2, Inhibin B, etc.
    MeSH term(s) Animals ; Brain-Derived Neurotrophic Factor/genetics ; Brain-Derived Neurotrophic Factor/metabolism ; DNA, Mitochondrial/drug effects ; Drugs, Chinese Herbal/therapeutic use ; Embryo Implantation/drug effects ; Female ; Gene Expression Regulation/drug effects ; Mice ; Ovarian Follicle/drug effects ; Ovarian Follicle/growth & development ; Ovarian Reserve/drug effects ; RNA, Messenger
    Chemical Substances Brain-Derived Neurotrophic Factor ; DNA, Mitochondrial ; Drugs, Chinese Herbal ; RNA, Messenger
    Language English
    Publishing date 2016-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1112577-9
    ISSN 1573-7330 ; 1058-0468
    ISSN (online) 1573-7330
    ISSN 1058-0468
    DOI 10.1007/s10815-016-0697-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Factors associated with utilization of reproductive healthcare services among migrant women workers in Chong Qing, China.

    Su, Shu / Zhang, Fan / Liu, Qin / Wang, Yang / Wen, Jing / Tang, Xiaojun / Zhang, Lei

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2014  Volume 127, Issue 1, Page(s) 66–68

    Abstract: ... in Chong Qing, China, and provide suggestions to improve the utilization of these services by young women ... policy-makers in Chong Qing, China.: Results: Women workers seldom visited hospitals and did so only ...

    Abstract Objective: To investigate the use of reproductive healthcare services among migrant women workers in Chong Qing, China, and provide suggestions to improve the utilization of these services by young women.
    Methods: In a qualitative interview-based study between March, 2013 and June, 2013, personal in-depth interviews were conducted among young women workers, factory doctors, healthcare service providers, and policy-makers in Chong Qing, China.
    Results: Women workers seldom visited hospitals and did so only when their pain became unbearable. The workers' use of reproductive healthcare services was particularly influenced by the high cost of hospitalization and long waiting periods. Factory doctors could only solve minor problems. Public healthcare providers stated that migrant women had a higher morbidity rate from reproductive tract infections as compared with local women. The policy-makers considered that the health system was beneficial to women's reproductive health; however, few workers had good comprehension of government policies.
    Conclusion: Migrant women workers are vulnerable owing to lack of reproductive health care. The government and both social and health enterprise should consider the convenience of these women and the affordability of treatments when formulating reproductive healthcare policies. Effective measures should be taken to improve the use of these services by migrant women workers.
    MeSH term(s) Adolescent ; Adult ; China ; Female ; Humans ; Reproductive Health Services/utilization ; Transients and Migrants/statistics & numerical data ; Young Adult
    Language English
    Publishing date 2014-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1016/j.ijgo.2014.04.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The multi-herbal formula Chong-Myung-Tang improves spatial memory and increases cell genesis in the dentate gyrus of aged mice.

    Liu, Lei / Zhang, Mingwei / Zhang, Ruifen / Lee, Mira / Wang, Zhen / Hou, Jingang / Sung, Chang-Keun

    Bioscience, biotechnology, and biochemistry

    2014  Volume 78, Issue 10, Page(s) 1710–1715

    Abstract: Chong-Myung-Tang (CMT) is a multi-herbal formula that has been used to improve memory ...

    Abstract Chong-Myung-Tang (CMT) is a multi-herbal formula that has been used to improve memory. However, the potential mechanism remains unknown. The present study investigated the effects of CMT (50, 100, and 200 mg/kg) on spatial memory of aged mice. The behavioral training tests indicated that 200 mg/kg CMT treatment can significantly improve spatial memory of aged mice in the Morris water maze. Moreover, cell survival was examined by injecting bromodeoxyuridine (BrdU) on the first three days. The result showed that 200 mg/kg CMT treatment significantly increased cell survival in the dentate gyrus. Cell proliferation was determined by injecting BrdU 2 h before the mice were killed. The result suggested that CMT treatments had no influence on cell proliferation in the dentate gyrus. Thus, an increase in cell survival in the dentate gyrus stimulated by CMT may be involved in the effect of CMT on spatial memory improvement.
    MeSH term(s) Aging/physiology ; Animals ; Behavior, Animal/drug effects ; Behavior, Animal/physiology ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Chemistry, Pharmaceutical ; Dentate Gyrus/cytology ; Dentate Gyrus/drug effects ; Dentate Gyrus/physiology ; Male ; Maze Learning/drug effects ; Mice ; Mice, Inbred ICR ; Neurogenesis/drug effects ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Spatial Memory/drug effects
    Chemical Substances Plant Extracts ; chong-myung-tang
    Language English
    Publishing date 2014
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1106450-x
    ISSN 1347-6947 ; 0916-8451
    ISSN (online) 1347-6947
    ISSN 0916-8451
    DOI 10.1080/09168451.2014.930319
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Evaluation of the liver protection and toxicity of Da-Huang-Zhe-Chong pill in rats.

    Xing, Xiao-yan / Zhao, Yan-ling / Jia, Lei / Kong, Wei-jun / Zhong, Yan-wei / Wang, Jia-bo / Zhang, Ping / Ren, Hui-ling / Xiao, Xiao-he

    Pharmaceutical biology

    2012  Volume 50, Issue 3, Page(s) 344–350

    Abstract: Context: Da-Huang-Zhe-Chong pill (DHZCP), a classical traditional Chinese formula, consists of 12 ...

    Abstract Context: Da-Huang-Zhe-Chong pill (DHZCP), a classical traditional Chinese formula, consists of 12 crude drugs which have been widely used with significant therapeutic effects. Some drugs in this formula have toxicities that might result in some adverse effects of DHZCP.
    Objective: The liver protection and toxicity of DHZCP were first evaluated against chronic carbon tetrachloride (CCl(4))-induced liver injury in rats.
    Materials and methods: The rats were treated by intraperitoneal injection of 10% CCl(4) for 12 weeks. At the end of week 4, DHZCP at doses of 44 g/kg (high-dose group) and 22 g/kg (low-dose group) was intragastrically administered to CCl(4)-treated rats, once a day for four weeks. At the end of weeks 8 and 12, the general status of the rats, histopathology of liver, serum alanine aminotransaminase (ALT), aspartate aminotransaminase (AST), alkaline phosphatase (ALP) and total bilirubin (TBIL) levels were observed or determined and recorded. By correspondence analysis (CA) on biochemical markers and liver histopathological score (HS), the "dose-time-response" relationship of DHZCP on the hepatic injury rats was evaluated.
    Results: The results showed that DHZCP exhibited a significant protective effect on liver injury by reversing the biochemical parameters and histopathological changes. However, this hepatoprotective effect may be weakened, or even be transferred to toxicity with the increase of the administration dose (44 g·kg(-1)·d(-1)) and time (more than 2 months) of this formula. These results were consistent with the histopathological observation and the serum levels.
    Discussion and conclusion: Administration of proper dose and time of DHZCP could well play its hepatoprotective effect and even treat hepatitis, but the safety on liver should be considered when large-dose (44 g·kg(-1)·d(-1)) DHZCP is used for long time (more than 2 months). We suggest that the administration dose and time of DHZCP in clinical use should not be increased and prolonged, and simultaneously liver function should be regularly monitored.
    MeSH term(s) Animals ; Carbon Tetrachloride/toxicity ; Dose-Response Relationship, Drug ; Drugs, Chinese Herbal/administration & dosage ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/toxicity ; Female ; Injections, Intraperitoneal ; Liver Diseases/physiopathology ; Liver Diseases/prevention & control ; Liver Function Tests ; Male ; Protective Agents/administration & dosage ; Protective Agents/pharmacology ; Protective Agents/toxicity ; Rats ; Rats, Sprague-Dawley ; Time Factors
    Chemical Substances Dahuang Zhechong pill ; Drugs, Chinese Herbal ; Protective Agents ; Carbon Tetrachloride (CL2T97X0V0)
    Language English
    Publishing date 2012-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1440131-9
    ISSN 1744-5116 ; 1388-0209
    ISSN (online) 1744-5116
    ISSN 1388-0209
    DOI 10.3109/13880209.2011.604333
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Cao ping hai chong

    Zhang, Qingwen / Liu, Kaijian / Wang, Gang

    (Cao ping quan jing)

    1999  

    Author's details Zhu bian Zhang Qingwen, Liu Kaijian, Wang Gang, fu zhu bian Ding Jun, Xu Jing
    Series title Cao ping quan jing
    Keywords Turfgrasses/Diseases and pests/Control
    Language Chinese ; Latin
    Size 1, 3, 247 p., [2] p. of plates :, ill. (some col.) ;, 23 cm.
    Edition Di 1 ban.
    Publisher Zhongguo ling ye chu ban she ; Xin hua shu dian Beijing fa xing suo fa xing
    Publishing place Beijing Shi
    Document type Book
    Note Terminologies also in Latin.
    ISBN 750382249X ; 9787503822490
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: The multi-herbal formula Chong-Myung-Tang improves spatial memory and increases cell genesis in the dentate gyrus of aged mice

    Liu, Lei / Zhang, Mingwei / Zhang, Ruifen / Lee, Mira / Wang, Zhen / Hou, Jingang / Sung, Chang-Keun

    Bioscience, biotechnology, and biochemistry. 2014 Oct. 3, v. 78, no. 10

    2014  

    Abstract: Chong-Myung-Tang (CMT) is a multi-herbal formula that has been used to improve memory ...

    Abstract Chong-Myung-Tang (CMT) is a multi-herbal formula that has been used to improve memory. However, the potential mechanism remains unknown. The present study investigated the effects of CMT (50, 100, and 200 mg/kg) on spatial memory of aged mice. The behavioral training tests indicated that 200 mg/kg CMT treatment can significantly improve spatial memory of aged mice in the Morris water maze. Moreover, cell survival was examined by injecting bromodeoxyuridine (BrdU) on the first three days. The result showed that 200 mg/kg CMT treatment significantly increased cell survival in the dentate gyrus. Cell proliferation was determined by injecting BrdU 2 h before the mice were killed. The result suggested that CMT treatments had no influence on cell proliferation in the dentate gyrus. Thus, an increase in cell survival in the dentate gyrus stimulated by CMT may be involved in the effect of CMT on spatial memory improvement.
    Keywords biochemistry ; biotechnology ; cell proliferation ; cell viability ; spatial memory
    Language English
    Dates of publication 2014-1003
    Size p. 1710-1715.
    Publishing place Taylor & Francis
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 1106450-x
    ISSN 1347-6947 ; 0916-8451
    ISSN (online) 1347-6947
    ISSN 0916-8451
    DOI 10.1080/09168451.2014.930319
    Database NAL-Catalogue (AGRICOLA)

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  8. Book: Kun chong sheng wu hua xue

    Wang, Yinchang

    2001  

    Author's details Wang Yinchang zhu bian
    Keywords Insects/Physiology. ; Insect biochemistry.
    Language Chinese
    Size 2, 11, 488 p. :, ill. ;, 27 cm.
    Edition Di 1 ban.
    Publisher Zhongguo nong ye chu ban she ; Xin hua shu dian Beijing fa xing suo fa xing
    Publishing place Beijing shi
    Document type Book
    ISBN 7109065626 ; 9787109065628
    Database NAL-Catalogue (AGRICOLA)

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  9. Book: Kan tu zhen zhi shi yong jun bing chong hai

    Wang, Bo

    (Kan tu zhen zhi zhi wu bing chong hai cong shu)

    2003  

    Author's details Wang Bo bian zhu
    Series title Kan tu zhen zhi zhi wu bing chong hai cong shu
    Keywords Edible mushrooms/Diseases and pests/Control.
    Language Chinese
    Size 130 p. :, ill. ;, 19 cm.
    Edition Di 1 ban.
    Publisher Sichuan ke xue ji shu chu ban she
    Publishing place Chengdu
    Document type Book
    ISBN 7536450478 ; 9787536450479
    Database NAL-Catalogue (AGRICOLA)

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  10. Book: Tu jie shu cai bing chong hai fang zhi

    Wang, Jiuxing

    2002  

    Title variant Shu cai bing chong hai fang zhi
    Author's details Wang Jiuxing bian zhu
    Keywords Vegetables/Diseases and pests/Control.
    Language Chinese
    Dates of publication 2002-9999
    Size v. :, col. ill. ;, 26 cm.
    Edition Di 1 ban.
    Publisher Tianjin ke xue ji shu chu ban she ; Xin hua shu dian Tianjin fa xing suo fa xing
    Publishing place Tianjin Shi
    Document type Book
    ISBN 7530831437 ; 9787530831434
    Database NAL-Catalogue (AGRICOLA)

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