Article: Three new 2-(2-phenylethyl)chromones from ‘Chong-lou’ agarwood of Aquilaria sinensis
Phytochemical Society of Europe Phytochemistry letters. 2022 Oct., v. 51
2022
Abstract: ... isolated from ‘Chong-lou’ agarwood originating from Aquilaria sinensis for the first time. Their new ...
Abstract | Three new 2-(2-phenylethyl)chromones (1, 2 and 3), together with four known analogues 4~7 were isolated from ‘Chong-lou’ agarwood originating from Aquilaria sinensis for the first time. Their new structures were elucidated on the basis of spectroscopic techniques (UV, IR, MS, 1D and 2D NMR), as well as by comparison with the literature data. Compounds 6 and 7 exhibited significant cytotoxicity against human cancer cell line K562 with IC₅₀ values of 19.79 ± 0.03 and 21.39 ± 0.05 μM, respectively. |
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Keywords | Aquilaria sinensis ; cytotoxicity ; humans ; neoplasm cells ; plant biochemistry |
Language | English |
Dates of publication | 2022-10 |
Size | p. 86-90. |
Publishing place | Elsevier Ltd |
Document type | Article |
ISSN | 1874-3900 |
DOI | 10.1016/j.phytol.2022.07.009 |
Database | NAL-Catalogue (AGRICOLA) |
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