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Article ; Online: The impact of dry eye disease on retinal image quality in children.

Song, Desheng / Zhou, Lu

Contact lens & anterior eye : the journal of the British Contact Lens Association

2024 , Page(s) 102168

Abstract: Background and objectives: Dry eye disease (DED) is increasingly prevalent, resultinginhigher morbidityamong children. This study evaluates the impact of DED severity on visual quality using double-pass technology, focusing on dynamic observation of the ...

Abstract	Background and objectives: Dry eye disease (DED) is increasingly prevalent, resultinginhigher morbidityamong children. This study evaluates the impact of DED severity on visual quality using double-pass technology, focusing on dynamic observation of the ocular light scatter in pediatric DED cases. Method: In this non-interventional, cross-sectional study, a mild DED group (37 cases, 37 eyes), a moderate DED group (40 cases, 40 eyes), and a control group of healthy children (35 cases, 35 eyes) were examined. Measurements included the Schirmer I test, tear film break-up time (BUT), and vision-related quality of life assessments using the Modified Ocular Surface Disease Index (OSDI) questionnaires. Participants underwent visual quality analysis using double-pass technology, which measured the modulation transfer function cut-off frequency value (MTF cutoff), Strehl ratio (SR), objective scatter index (OSI), and OQAS-II value (OQAS-II value OV100%, OQAS-II value OV 20%, and OQAS-II value OV 9%) under natural conditions. Additionally, dynamic changes in OSI post-blinking, Tear film mean-OSI (TFM-OSI), and the corresponding standard deviation OSI (SD-OSI) were recorded. Results: Statistically significant differences were observed among the groups in modulation transfer function cutoff, Strehl ratio, OSI, OQAS-II value OV 100 %, OQAs-II value OV 20 %, OQAs-II value OV 9 %, tear film mean OSI, and standard deviation OSI (P < 0.05). As DED severity increased, tear film mean OSI significantly rose, while modulation transfer function cutoff, strehl ratio, OQAS-II value OV 100 %, OQAS-II value OV 20 %, OQAS-II value OV 9 % notably declined. All optical quality parameters were correlated with BUT, with no association observed with age, sex, or Schirmer I test. Conclusion: Dual-channel technology objectively assesses visual quality in pediatric DED, demonstrating that tear film scattering significantly affects retinal imaging and visual quality in children with DED.
Language	English
Publishing date	2024-04-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2004847-6
ISSN	1476-5411 ; 1367-0484
ISSN (online)	1476-5411
ISSN	1367-0484
DOI	10.1016/j.clae.2024.102168
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Game analysis of enterprise safety investment and employee safety behavior strategy evolution in high-risk industries

Youcai Xie / Gang Lu / Desheng Lai / Meng Tao

Heliyon, Vol 9, Iss 4, Pp e15081- (2023)

2023

Abstract: This paper aims to explore the influential relationship between the decision-making of investment of enterprise safety and employee safety behavior strategy selection, thus improve the effectiveness of decision-making. Based on traditional game theory, ... ...

Abstract	This paper aims to explore the influential relationship between the decision-making of investment of enterprise safety and employee safety behavior strategy selection, thus improve the effectiveness of decision-making. Based on traditional game theory, this paper establishes an evolutionary game model of enterprise safety investment and employee safety behavior strategy selection, and conducts numerical simulation analysis. The result shows:when the security investment cost is greater than the security investment benefit, the employee's security behavior strategy choice is significant for the enterprise security investment strategy decision; when the security investment benefit is greater than the security investment cost, the enterprise security investment decision is not affected by the employee safety behavior strategy; the choice of employee safety behavior strategy is not affected by the choice of enterprise safety investment strategy. The conclusion can provide a reference basis for enterprise safety production decision-making, which has certain theoretical and practical significance.
Keywords	Security investment ; Safety behavior ; Evolutionary game ; Numerical simulation ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Game analysis of enterprise safety investment and employee safety behavior strategy evolution in high-risk industries.

Xie, Youcai / Lu, Gang / Lai, Desheng / Tao, Meng

Heliyon

2023 Volume 9, Issue 4, Page(s) e15081

Abstract	This paper aims to explore the influential relationship between the decision-making of investment of enterprise safety and employee safety behavior strategy selection, thus improve the effectiveness of decision-making. Based on traditional game theory, this paper establishes an evolutionary game model of enterprise safety investment and employee safety behavior strategy selection, and conducts numerical simulation analysis. The result shows:when the security investment cost is greater than the security investment benefit, the employee's security behavior strategy choice is significant for the enterprise security investment strategy decision; when the security investment benefit is greater than the security investment cost, the enterprise security investment decision is not affected by the employee safety behavior strategy; the choice of employee safety behavior strategy is not affected by the choice of enterprise safety investment strategy. The conclusion can provide a reference basis for enterprise safety production decision-making, which has certain theoretical and practical significance.
Language	English
Publishing date	2023-04-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e15081
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The efficacy and safety of hydrotherapy in patients with knee osteoarthritis: A protocol for systematic review and meta-analysis.

Zhang, Xu / Xue, Tianle / Hou, Desheng / Lu, Cheng

Medicine

2023 Volume 102, Issue 8, Page(s) e33027

Abstract: Background: Knee osteoarthritis (OA) is a common clinical degenerative disease of the joints, which is prone to occur in middle-aged and elderly people. At present, the disease cannot be cured, it is mostly treated with drugs to relieve symptoms, ... ...

Abstract	Background: Knee osteoarthritis (OA) is a common clinical degenerative disease of the joints, which is prone to occur in middle-aged and elderly people. At present, the disease cannot be cured, it is mostly treated with drugs to relieve symptoms, improve joint function, protect cartilage, such as glucosamine, anti-inflammatory and analgesic drugs, and but the efficacy is not lasting and the recurrence rate is high. Hydrotherapy has become a long-term alternative therapy in China and is receiving increasing attention. We perform a protocol for systematic review and meta-analysis to determine the efficacy and safety of a hydrotherapy program in individuals living with knee OA. Methods: This protocol will be designed in accordance with the preferred reporting items for systematic reviews and meta-analysis protocols. It is registered on the international prospective register of systematic reviews (No. CRD42022365564). We will search the following databases: The Cochrane Skin Group Trials Register, MEDLINE, EMBASE, The Cochrane central register of controlled trials, Chinese biomedical literature database, Chinese medical current content and China national knowledge infrastructure. The risk of bias of the included studies will be appraised using the Cochrane collaboration tool. Statistical analysis will be performed using IBM SPSS Statistics (Armonk, NY). Results: This systematic review will summarize the short- and long-term clinical outcomes of hydrotherapy for knee OA. Conclusion: The findings from this review will establish the quality of currently available evidence, which will determine the need for further studies to establish the true effect size of hydrotherapy in knee OA.
MeSH term(s)	Aged ; Middle Aged ; Humans ; Osteoarthritis, Knee/therapy ; Systematic Reviews as Topic ; Meta-Analysis as Topic ; Glucosamine/therapeutic use ; Hydrotherapy ; Review Literature as Topic
Chemical Substances	Glucosamine (N08U5BOQ1K)
Language	English
Publishing date	2023-02-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000033027
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: The Impact of Preoperative Adaptive Training on Postoperative Outcomes in Lumbar Spine Fusion Surgery for Lumbar Disc Herniation: A Retrospective Analysis.

Lu, Jiawei / Guo, Kai / Liu, Elaine Zhiqing / Braun, Corben / Huang, Yufeng / Wu, Desheng

Journal of pain research

2024 Volume 17, Page(s) 73–81

Abstract: Purpose: Lumbar disc herniation, often treated with surgical decompression when conservative measures fail, presents challenges due to prolonged prone positioning in surgeries. This retrospective study evaluates the benefits of preoperative adaptive ... ...

Abstract	Purpose: Lumbar disc herniation, often treated with surgical decompression when conservative measures fail, presents challenges due to prolonged prone positioning in surgeries. This retrospective study evaluates the benefits of preoperative adaptive training to mitigate post-surgical physiological changes. Patients and methods: A review of medical records from June 2021 to March 2023 identified 170 patients unresponsive to conservative treatments. Grouped into adaptive training and control groups based on historical data, the former had undergone exercises to prepare for surgery and postoperative changes. Vital signs and VAS scores were extracted from patient records to assess training impact. Results: The adaptive training group demonstrated stabilized vital signs intraoperatively, with a notable improvement in surgical exposure compared to the control group. However, there were no significant differences in operative time or blood loss between the groups. Additionally, postoperative VAS scores showed no significant improvement in the adaptive training group at follow-up intervals of 14 days, 1 month, and 3 months post-operation, compared to the control group. Conclusion: Our study reveals that preoperative adaptive training stabilizes intraoperative blood pressure fluctuations in lumbar disc herniation surgeries. However, this stabilization does not significantly impact long-term postoperative pain management. This highlights the need for further research to explore comprehensive strategies that effectively combine preoperative training with postoperative care.
Language	English
Publishing date	2024-01-05
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2495284-9
ISSN	1178-7090
ISSN	1178-7090
DOI	10.2147/JPR.S442239
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A PANoptosis pattern to predict prognosis and immunotherapy response in head and neck squamous cell carcinoma.

Gao, Feng / Zhang, Minghuan / Ying, Zhenguang / Li, Wanqiu / Lu, Desheng / Wang, Xia / Sha, Ou

Heliyon

2024 Volume 10, Issue 5, Page(s) e27162

Abstract: Individuals diagnosed with head and neck squamous cell carcinoma (HNSCC) experience a significant occurrence rate and are susceptible to premature spreading, resulting in a bleak outlook. Therapeutic approaches, such as chemotherapy, targeted therapy, ... ...

Abstract	Individuals diagnosed with head and neck squamous cell carcinoma (HNSCC) experience a significant occurrence rate and are susceptible to premature spreading, resulting in a bleak outlook. Therapeutic approaches, such as chemotherapy, targeted therapy, and immunotherapy, may exhibit primary and acquired resistance during the advanced phases of HNSCC. There is currently no viable solution to tackle this issue. PANoptosis-a type of non-apoptotic cell death-is a recently identified mechanism of cellular demise that entails communication and synchronization among thermal apoptosis, apoptosis, and necrosis mechanisms. However, the extent to which PANoptosis-associated genes (PRG) contribute to the forecast and immune reaction of HNSCC remains mostly undisclosed. The present study aimed to thoroughly analyze the potential importance of PRG in HNSCC and report our discoveries. We systematically analyzed 19 PRG from previous studies and clinical data from HNSCC patients to establish a PAN-related signature and assess its prognostic, predictive potential. Afterward, the patient information was separated into two gene patterns that corresponded to each other, and the analysis focused on the connection between patient prognosis, immune status, and cancer immunotherapy. The PAN score was found to correlate with survival rates, immune systems, and cancer-related pathways. We then validated the malignant role of CD27 among them in HNSCC. In summary, we demonstrated the effectiveness of PAN.Score-based molecular clustering and prognostic features in predicting the outcome of HNSCC. The discovery we made could enhance our comprehension of the significance of PAN.Score in HNSCC and facilitate the development of more effective treatment approaches.
Language	English
Publishing date	2024-02-27
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e27162
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Game analysis of enterprise safety investment and employee safety behavior strategy evolution in high-risk industries

Xie, Youcai / Lu, Gang / Lai, Desheng / Tao, Meng

Heliyon. 2023 Apr., v. 9, no. 4 p.e15081-

2023

Abstract	This paper aims to explore the influential relationship between the decision-making of investment of enterprise safety and employee safety behavior strategy selection, thus improve the effectiveness of decision-making. Based on traditional game theory, this paper establishes an evolutionary game model of enterprise safety investment and employee safety behavior strategy selection, and conducts numerical simulation analysis. The result shows:when the security investment cost is greater than the security investment benefit, the employee's security behavior strategy choice is significant for the enterprise security investment strategy decision; when the security investment benefit is greater than the security investment cost, the enterprise security investment decision is not affected by the employee safety behavior strategy; the choice of employee safety behavior strategy is not affected by the choice of enterprise safety investment strategy. The conclusion can provide a reference basis for enterprise safety production decision-making, which has certain theoretical and practical significance.
Keywords	business enterprises ; decision making ; evolution ; game theory ; simulation models ; Security investment ; Safety behavior ; Evolutionary game ; Numerical simulation
Language	English
Dates of publication	2023-04
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e15081
Database	NAL-Catalogue (AGRICOLA)

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Article: Gender, Socioeconomic Status, Cultural Differences, Education, Family Size and Procrastination: A Sociodemographic Meta-Analysis.

Lu, Desheng / He, Yiheng / Tan, Yu

Frontiers in psychology

2022 Volume 12, Page(s) 719425

Abstract: Procrastination describes a ubiquitous scenario in which individuals voluntarily postpone scheduled activities at the expense of adverse consequences. Steel (2007) pioneered a meta-analysis to explicitly reveal the nature of procrastination and sparked ... ...

Abstract	Procrastination describes a ubiquitous scenario in which individuals voluntarily postpone scheduled activities at the expense of adverse consequences. Steel (2007) pioneered a meta-analysis to explicitly reveal the nature of procrastination and sparked intensive research on its demographic characteristics. However, conflicting and heterogeneous findings reported in the existing literature make it difficult to draw reliable conclusions. In addition, there is still room to further investigate on more sociodemographic features that include socioeconomic status, cultural differences and procrastination education. To this end, we performed quantitative sociodemographic meta-analyses (
Language	English
Publishing date	2022-01-05
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2021.719425
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Mutation N856K in spike reduces fusogenicity and infectivity of Omicron BA.1.

Sun, Chunyun / Wang, Huiyu / Yang, Ji / Kong, Desheng / Chen, Yuning / Wang, Haiyue / Sun, Lingling / Lu, Jianbo / Teng, Min / Xie, Liangzhi

Signal transduction and targeted therapy

2023 Volume 8, Issue 1, Page(s) 75

Language	English
Publishing date	2023-02-22
Publishing country	England
Document type	Letter
ZDB-ID	2886872-9
ISSN	2059-3635 ; 2095-9907
ISSN (online)	2059-3635
ISSN	2095-9907
DOI	10.1038/s41392-022-01281-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Advances in Our Understanding of the Mechanism of Action of Drugs (including Traditional Chinese Medicines) for the Intervention and Treatment of Osteoporosis.

Lu, Junjie / Hu, Desheng / Ma, Chen / Shuai, Bo

Frontiers in pharmacology

2022 Volume 13, Page(s) 938447

Abstract: Osteoporosis (OP) is known as a silent disease in which the loss of bone mass and bone density does not cause obvious symptoms, resulting in insufficient treatment and preventive measures. The losses of bone mass and bone density become more severe over ... ...

Abstract	Osteoporosis (OP) is known as a silent disease in which the loss of bone mass and bone density does not cause obvious symptoms, resulting in insufficient treatment and preventive measures. The losses of bone mass and bone density become more severe over time and an only small percentage of patients are diagnosed when OP-related fractures occur. The high disability and mortality rates of OP-related fractures cause great psychological and physical damage and impose a heavy economic burden on individuals and society. Therefore, early intervention and treatment must be emphasized to achieve the overall goal of reducing the fracture risk. Anti-OP drugs are currently divided into three classes: antiresorptive agents, anabolic agents, and drugs with other mechanisms. In this review, research progress related to common anti-OP drugs in these three classes as well as targeted therapies is summarized to help researchers and clinicians understand their mechanisms of action and to promote pharmacological research and novel drug development.
Language	English
Publishing date	2022-06-14
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2022.938447
Database	MEDical Literature Analysis and Retrieval System OnLINE

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