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  1. Article ; Online: Climbing the STAIRs to SPAN the Clinical Translation Gap: Recent Advances in Multicenter Preclinical Stroke Trials.

    Turner, Renée J / Farr, Tracy D

    Stroke

    2024  

    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.124.045998
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Book ; Online ; E-Book: Pocket guide to quality improvement in healthcare

    Roberts-Turner, Reneè / Shah, Rahul K.

    2021  

    Author's details Reneè Roberts-Turner, Rahul K. Shah, editors
    Keywords Medical care/Quality control ; Assistència sanitària
    Subject code 362.10685
    Language English
    Size 1 online resource (337 pages)
    Publisher Springer
    Publishing place Cham, Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-70780-6 ; 3-030-70779-2 ; 978-3-030-70780-4 ; 978-3-030-70779-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Coming full circle: a critical review of the historical changes in governance, nutrition and food security of Labrador Inuit between 1500 and 2005

    Bowers, Renee / Turner, Gail / Graham, Ian D. / Furgal, Chris / Dubois, Lise

    Food, Culture & Society. 2023 May 27, v. 26, no. 3 p.545-570

    2023  

    Abstract: Labrador Inuit are an Indigenous People from northern Labrador, within the province of Newfoundland and Labrador, Canada. Prior to European contact, Labrador Inuit were self-reliant. However, historical relationships with Christian missionaries, the ... ...

    Abstract Labrador Inuit are an Indigenous People from northern Labrador, within the province of Newfoundland and Labrador, Canada. Prior to European contact, Labrador Inuit were self-reliant. However, historical relationships with Christian missionaries, the Government of Newfoundland and Labrador, and the Government of Canada impacted their relationship with food, access to food, and the physical and social health of Labrador Inuit. This review is based on the stages of colonization. It uses a critical dietetics lens to examine the extrinsic causes of nutrition and food security issues that resulted from colonization, and describes the interventions implemented to address them. Moreover, the review shows the resilience and adaptability of Labrador Inuit as they came full circle from self-sufficient Labrador Inuit in the 1500s, to sign the first Inuit land claim agreement in Canada and form the Nunatsiavut Government in 2005.
    Keywords Inuit ; dietetics ; food security ; governance ; Newfoundland and Labrador ; Labrador Inuit ; nutrition ; policy ; colonization
    Language English
    Dates of publication 2023-0527
    Size p. 545-570.
    Publishing place Routledge
    Document type Article ; Online
    ZDB-ID 2240542-2
    ISSN 1751-7443 ; 1552-8014
    ISSN (online) 1751-7443
    ISSN 1552-8014
    DOI 10.1080/15528014.2021.2025311
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 7677: Show issues

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  4. Article: Through a Different Lens: Occupational Health of Sex-Working Young Trans Women.

    Fisher, Marla Renee / Turner, Caitlin / McFarland, Willi / Breslow, Aaron Samuel / Wilson, Erin C / Arayasirikul, Sean

    Transgender health

    2023  Volume 8, Issue 2, Page(s) 200–206

    Abstract: Purpose: Sex work is a common form of work among young trans women (YTW).: Methods: Using an occupational health frame, we measured associations between demographics, sex work, and vocational outcomes in 18-month visit data from the SHINE study (: ... ...

    Abstract Purpose: Sex work is a common form of work among young trans women (YTW).
    Methods: Using an occupational health frame, we measured associations between demographics, sex work, and vocational outcomes in 18-month visit data from the SHINE study (
    Results: Overall, 41.8% reported lifetime sex work, primarily escorting/paid sex. Motivations included "better pay" and "can't get a job due to gender discrimination." Occupational injuries included anxiety (53.6%) and depression (50%), with significantly higher relative risk for YTW doing multiple types of sex work. Criminalization experiences (i.e., incarceration, arrests, and police interaction) were common.
    Conclusion: Results echo calls for sex worker-affirming mental health care for YTW.
    Language English
    Publishing date 2023-03-31
    Publishing country United States
    Document type Journal Article
    ISSN 2688-4887
    ISSN 2688-4887
    DOI 10.1089/trgh.2021.0109
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  5. Article ; Online: Understanding caregiver perspectives on challenges and solutions to pediatric asthma care for children with a previous hospital admission: a multi-site qualitative study.

    Jones, Renee / Turner, Brittany / Perera, Prescilla / Hiscock, Harriet / Chen, Katherine

    The Journal of asthma : official journal of the Association for the Care of Asthma

    2021  Volume 59, Issue 10, Page(s) 1973–1980

    Abstract: Objective: Pediatric hospital admissions for asthma provide an opportunity to trigger a review of the current management with an aim of preventing readmissions. However, caregiver voices on how best to improve care are missing.: Methods: As part of a ...

    Abstract Objective: Pediatric hospital admissions for asthma provide an opportunity to trigger a review of the current management with an aim of preventing readmissions. However, caregiver voices on how best to improve care are missing.
    Methods: As part of a larger, mixed methods cohort study, we identified caregivers of children aged 3-18 years who had an index hospital admission to a tertiary pediatric, mixed adult and pediatric, or regional hospital in Victoria, Australia, between 1st September 2017 and 31st August 2018 with a discharge diagnosis of "Asthma" or "Wheeze" based on International Classification of Disease-10 coding. We conducted qualitative semi-structured interviews with a purposive sample of 39 caregivers. We used content analysis to identify themes from the data.
    Results: Caregivers identified both challenges associated with asthma care for children with a previous hospital admission as well as solutions to improve care and potentially reduce readmissions. Key challenges included: unclear pathways for follow up care, inconsistent advice, lack of personalized management, delays in getting a diagnosis, delays in the prescription of a preventer medication, and difficulty accessing primary care during exacerbations. Follow up with an "asthma specialist", early access to a trial of preventer medication, personalized Written Asthma Action Plans and increased access to and quality of community-based asthma support services were identified as key solutions.
    Conclusions: Caregivers have identified several potential solutions that could be implemented to improve care and possibly reduce pediatric asthma hospital readmissions. The challenge now is to co-design, embed and evaluate these in healthcare systems.
    Supplemental data for this article can be accessed at publisher's website.
    MeSH term(s) Adult ; Asthma/drug therapy ; Caregivers ; Child ; Cohort Studies ; Hospitalization ; Hospitals, Pediatric ; Humans
    Language English
    Publishing date 2021-10-07
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 603816-5
    ISSN 1532-4303 ; 0277-0903
    ISSN (online) 1532-4303
    ISSN 0277-0903
    DOI 10.1080/02770903.2021.1984528
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 18: Show issues Location:
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  6. Article ; Online: Evaluating the effect of post-traumatic hypoxia on the development of axonal injury following traumatic brain injury in sheep.

    Sharkey, Jessica M / Quarrington, Ryan D / Krieg, Justin L / Kaukas, Lola / Turner, Renee J / Leonard, Anna / Jones, Claire F / Corrigan, Frances

    Brain research

    2023  Volume 1817, Page(s) 148475

    Abstract: Damage to the axonal white matter tracts within the brain is a key cause of neurological impairment and long-term disability following traumatic brain injury (TBI). Understanding how axonal injury develops following TBI requires gyrencephalic models that ...

    Abstract Damage to the axonal white matter tracts within the brain is a key cause of neurological impairment and long-term disability following traumatic brain injury (TBI). Understanding how axonal injury develops following TBI requires gyrencephalic models that undergo shear strain and tissue deformation similar to the clinical situation and investigation of the effects of post-injury insults like hypoxia. The aim of this study was to determine the effect of post-traumatic hypoxia on axonal injury and inflammation in a sheep model of TBI. Fourteen male Merino sheep were allocated to receive a single TBI via a modified humane captive bolt animal stunner, or sham surgery, followed by either a 15 min period of hypoxia or maintenance of normoxia. Head kinematics were measured in injured animals. Brains were assessed for axonal damage, microglia and astrocyte accumulation and inflammatory cytokine expression at 4 hrs following injury. Early axonal injury was characterised by calpain activation, with significantly increased SNTF immunoreactivity, a proteolytic fragment of alpha-II spectrin, but not with impaired axonal transport, as measured by amyloid precursor protein (APP) immunoreactivity. Early axonal injury was associated with an increase in GFAP levels within the CSF, but not with increases in IBA1 or GFAP+ve cells, nor in levels of TNFα, IL1β or IL6 within the cerebrospinal fluid or white matter. No additive effect of post-injury hypoxia was noted on axonal injury or inflammation. This study provides further support that axonal injury post-TBI is driven by different pathophysiological mechanisms, and detection requires specific markers targeting multiple injury mechanisms. Treatment may also need to be tailored for injury severity and timing post-injury to target the correct injury pathway.
    MeSH term(s) Male ; Animals ; Sheep ; Brain Injuries/metabolism ; Brain Injuries, Traumatic/complications ; Brain Injuries, Traumatic/metabolism ; Brain/metabolism ; Hypoxia/metabolism ; Inflammation/metabolism
    Language English
    Publishing date 2023-07-01
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1200-2
    ISSN 1872-6240 ; 0006-8993
    ISSN (online) 1872-6240
    ISSN 0006-8993
    DOI 10.1016/j.brainres.2023.148475
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    Zs.A 161: Show issues Location:
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  7. Article: Identifying the Phenotypes of Diffuse Axonal Injury Following Traumatic Brain Injury.

    Krieg, Justin L / Leonard, Anna V / Turner, Renée J / Corrigan, Frances

    Brain sciences

    2023  Volume 13, Issue 11

    Abstract: Diffuse axonal injury (DAI) is a significant feature of traumatic brain injury (TBI) across all injury severities and is driven by the primary mechanical insult and secondary biochemical injury phases. Axons comprise an outer cell membrane, the axolemma ... ...

    Abstract Diffuse axonal injury (DAI) is a significant feature of traumatic brain injury (TBI) across all injury severities and is driven by the primary mechanical insult and secondary biochemical injury phases. Axons comprise an outer cell membrane, the axolemma which is anchored to the cytoskeletal network with spectrin tetramers and actin rings. Neurofilaments act as space-filling structural polymers that surround the central core of microtubules, which facilitate axonal transport. TBI has differential effects on these cytoskeletal components, with axons in the same white matter tract showing a range of different cytoskeletal and axolemma alterations with different patterns of temporal evolution. These require different antibodies for detection in post-mortem tissue. Here, a comprehensive discussion of the evolution of axonal injury within different cytoskeletal elements is provided, alongside the most appropriate methods of detection and their temporal profiles. Accumulation of amyloid precursor protein (APP) as a result of disruption of axonal transport due to microtubule failure remains the most sensitive marker of axonal injury, both acutely and chronically. However, a subset of injured axons demonstrate different pathology, which cannot be detected via APP immunoreactivity, including degradation of spectrin and alterations in neurofilaments. Furthermore, recent work has highlighted the node of Ranvier and the axon initial segment as particularly vulnerable sites to axonal injury, with loss of sodium channels persisting beyond the acute phase post-injury in axons without APP pathology. Given the heterogenous response of axons to TBI, further characterization is required in the chronic phase to understand how axonal injury evolves temporally, which may help inform pharmacological interventions.
    Language English
    Publishing date 2023-11-20
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci13111607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Assessment of a Non-Invasive Brain Oximeter in a Sheep Model of Acute Brain Injury.

    Dixon, Barry / Turner, Renee / Christou, Chris

    Medical devices (Auckland, N.Z.)

    2019  Volume 12, Page(s) 479–487

    Abstract: Introduction: Evidence suggests treatments guided by brain oxygen levels improve patient outcomes following severe traumatic brain injury; however, brain oxygen levels are not routinely monitored as an effective non-invasive method has not been ... ...

    Abstract Introduction: Evidence suggests treatments guided by brain oxygen levels improve patient outcomes following severe traumatic brain injury; however, brain oxygen levels are not routinely monitored as an effective non-invasive method has not been established. We undertook a study, in a sheep model of acute brain injury, to assess a new non-invasive brain oximeter. The monitor uses the principles of pulse oximetry to record a pulse and oxygen levels.
    Methods: We studied 8 sheep. An acute increase in intracranial pressure was induced with an injection of blood into the cranial vault. The temporal changes in the brain oximeter, intracranial pressure and cerebral perfusion pressure were recorded. Simultaneous conventional skin pulse oximetry was also recorded to assess the possible influence of skin blood flow on the brain oximeter signal.
    Results: At baseline, a pulsatile waveform consistent with the brain circulation was obtained in 7 animals. The baseline brain pulse was quite distinct from the simultaneous conventional skin pulse and similar in shape to a central venous pressure waveform. Injection of blood into the cranial vault triggered an immediate increase in intracranial pressure and fall in cerebral perfusion pressure, by 60-s cerebral perfusion pressure recovered. The brain oximeter oxygen levels demonstrated similar changes with an immediate fall and recovery by 60 s. Periods of high intracranial pressure were also associated with high-frequency oscillations in the brain pulse waveform; there was, however, no change in the conventional skin pulse oximeter pulse waveform.
    Conclusion: The brain oximeter detected acute changes in both oxygen levels and the brain pulse waveform following an increase in intracranial pressure levels. The brain oximeter could assist clinicians in the management of acute brain injury.
    Keywords covid19
    Language English
    Publishing date 2019-12-03
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2520731-3
    ISSN 1179-1470
    ISSN 1179-1470
    DOI 10.2147/MDER.S235804
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  9. Article ; Online: Barriers and enablers to hepatitis C treatment among clients of Aboriginal Community Controlled Health Services in South East Queensland, Australia: a qualitative enquiry.

    Puljevic, Cheneal / Massi, Luciana / Brown, Renee / Mills, Richard / Turner, Lyle / Smirnov, Andrew / Selvey, Linda A

    Australian journal of primary health

    2022  Volume 28, Issue 3, Page(s) 239–246

    Abstract: Background: Aboriginal and Torres Strait Islander Australians have disproportionately high rates of hepatitis C infection. Aboriginal Community Controlled Health Services play an important role in promoting hepatitis C treatment, but uptake is variable. ...

    Abstract Background: Aboriginal and Torres Strait Islander Australians have disproportionately high rates of hepatitis C infection. Aboriginal Community Controlled Health Services play an important role in promoting hepatitis C treatment, but uptake is variable. This study explores the service-level barriers and enablers to hepatitis C screening and treatment among clients of Aboriginal Community Controlled Health Services in South East Queensland.
    Methods: This qualitative study involved yarns with 16 clients and 40 healthcare providers. Thematic analysis was used to identify common barriers and enablers to hepatitis C screening and treatment.
    Results: Common barriers included healthcare providers' knowledge deficits and inaccurate perceptions of clients' ability to complete treatment, whereas clients described stigma that resulted in distrust of health care, and experiences of poor relationships and connections with healthcare providers. Enablers included Aboriginal governance of Aboriginal Community Controlled Health Services and the ease of direct-acting antiviral treatment.
    Conclusions: This study's findings point to the need for healthcare worker training focussing on client autonomy, reduced hepatitis C-related stigma, and consideration of clinicians' roles in increasing service engagement. Addressing the barriers to hepatitis C treatment through client-focussed service improvement may promote increased hepatitis C screening and treatment among Aboriginal and Torres Strait Islander Australians.
    MeSH term(s) Antiviral Agents ; Australia ; Community Health Services ; Health Services, Indigenous ; Hepatitis C, Chronic ; Humans ; Native Hawaiian or Other Pacific Islander ; Queensland
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2022-02-03
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2566332-X
    ISSN 1836-7399 ; 1448-7527
    ISSN (online) 1836-7399
    ISSN 1448-7527
    DOI 10.1071/PY21055
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  10. Article ; Online: The Effect of Exercise on Pain in People with Cancer: A Systematic Review with Meta-analysis.

    Plinsinga, Melanie Louise / Singh, Ben / Rose, Grace Laura / Clifford, Briana / Bailey, Tom George / Spence, Rosalind Renee / Turner, Jemma / Coppieters, Michel Willem / McCarthy, Alexandra Leigh / Hayes, Sandra Christine

    Sports medicine (Auckland, N.Z.)

    2023  Volume 53, Issue 9, Page(s) 1737–1752

    Abstract: Introduction: Cancer-related pain is common and undertreated. Exercise is known to have a pain-relieving effect in non-cancer pain.: Objectives: This systematic review aimed to evaluate (1) the effect of exercise on cancer-related pain in all cancers, ...

    Abstract Introduction: Cancer-related pain is common and undertreated. Exercise is known to have a pain-relieving effect in non-cancer pain.
    Objectives: This systematic review aimed to evaluate (1) the effect of exercise on cancer-related pain in all cancers, and (2) whether the effect of exercise differed according to exercise mode, degree of supervision, intervention duration and timing (during or after cancer treatment), pain types, measurement tool and cancer type.
    Methods: Electronic searches were undertaken in six databases to identify exercise studies evaluating pain in people with cancer, published prior to 11 January 2023. All stages of screening and data extraction were conducted independently by two authors. The Cochrane risk of bias tool for randomised trials (RoB 2) was used and overall strength of evidence was assessed using the GRADE approach. Meta-analyses were performed overall and by study design, exercise intervention and pain characteristics.
    Results: In total, 71 studies reported in 74 papers were eligible for inclusion. The overall meta-analysis included 5877 participants and showed reductions in pain favouring exercise (standardised mean difference - 0.45; 95% confidence interval - 0.62, - 0.28). For most (> 82%) of the subgroup analyses, the direction of effect favoured exercise compared with usual care, with effect sizes ranging from small to large (median effect size - 0.35; range - 0.03 to - 1.17). The overall strength of evidence for the effect of exercise on cancer-related pain was very low.
    Conclusion: The findings provide support that exercise participation does not worsen cancer-related pain and that it may be beneficial. Better pain categorisation and inclusion of more diverse cancer populations in future research would improve understanding of the extent of benefit and to whom.
    Prospero registration number: CRD42021266826.
    MeSH term(s) Humans ; Cancer Pain/therapy ; Exercise ; Neoplasms/complications ; Neoplasms/therapy ; Exercise Therapy ; Pain/etiology
    Language English
    Publishing date 2023-05-22
    Publishing country New Zealand
    Document type Meta-Analysis ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 605911-9
    ISSN 1179-2035 ; 0112-1642
    ISSN (online) 1179-2035
    ISSN 0112-1642
    DOI 10.1007/s40279-023-01862-9
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