LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 42940

Search options

  1. Article ; Online: Meet the authors: Yu Zhou, Ting Shan, and Feiyan Liu.

    Zhou, Yu / Shan, Ting / Liu, Feiyan

    Molecular cell

    2023  Volume 83, Issue 24, Page(s) 4439–4441

    Abstract: We talk to authors Yu Zhou, Ting Shan, and Feiyan Liu about their paper "m ...

    Abstract We talk to authors Yu Zhou, Ting Shan, and Feiyan Liu about their paper "m
    MeSH term(s) Tolnaftate
    Chemical Substances Tolnaftate (06KB629TKV)
    Language English
    Publishing date 2023-12-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1415236-8
    ISSN 1097-4164 ; 1097-2765
    ISSN (online) 1097-4164
    ISSN 1097-2765
    DOI 10.1016/j.molcel.2023.11.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Integrated Brain Metabolomics and Network Pharmacology Analysis to Reveal the Improvement Effect of Bai Chan Ting on Parkinson's Disease.

    Zhang, Na / Fu, Jiaqi / Gao, Xin / Lu, Fang / Lu, Yi / Liu, Shumin

    BioMed research international

    2022  Volume 2022, Page(s) 6113093

    Abstract: Background: Baichanting (BCT),a traditional Chinese medicine prescription, is a combination of : Materials and methods: By integrating network pharmacology with metabolomic research, the protective effect of BCT against PD was investigated using a ... ...

    Abstract Background: Baichanting (BCT),a traditional Chinese medicine prescription, is a combination of
    Materials and methods: By integrating network pharmacology with metabolomic research, the protective effect of BCT against PD was investigated using a transgenic mouse model for
    Results: 101 putative target genes were identified by the network pharmacology analysis in relation to the treatment of PD with BCT. According to the functional enrichment analysis, the proposed mechanism was primarily related to the transport of neurotransmitters, the metabolism of arachidonic acid, dopamine, and alpha-amino acids, as well as the transport of dopamine and the negative regulation of amino acid transport. 25 distinct endogenous metabolites were shown to be potential biomarkers for the BCT for treating PD based on metabolomics. These metabolites were mostly implicated in the important methionine and cysteine, tyrosine, histidine, and arginine and proline metabolic pathways. These results somewhat agreed with those of the network pharmacology analysis.
    Conclusions: In conclusion, this study showed that BCT could delay the occurrence and development of PD by improving the brain metabolic disorder of
    Language English
    Publishing date 2022-12-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2022/6113093
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: [Influence on orbicularis oculi muscle in the patients with facial neuritis treated with the penetra-ting needling at Cuanzhu (BL2) and Yuyao (EX-HN4) combined with the perpendicular needling at Shenmai (BL62)].

    Xu, Li-Wei / Quan, Xing-Miao / Song, Chun-Xia / Liu, Yu-Lan / Xu, Hong-Yan

    Zhen ci yan jiu = Acupuncture research

    2020  Volume 45, Issue 9, Page(s) 735–739

    Abstract: Objective: To explore the therapeutic effect on incomplete eyelid in the patients with facial neuritis treated with the penetrating needling at Cuanzhu (BL2) and Yuyao (EX-HN4) combined with the perpendicular needling at Shenmai (BL62).: Methods: A ... ...

    Abstract Objective: To explore the therapeutic effect on incomplete eyelid in the patients with facial neuritis treated with the penetrating needling at Cuanzhu (BL2) and Yuyao (EX-HN4) combined with the perpendicular needling at Shenmai (BL62).
    Methods: A total of 64 patients with facial neuritis, in compliance with the inclusion criteria, were randomized into a treatment group and a control group, with 32 cases in each. In the treatment group, the penetrating needling was applied to BL2 and EX-HN4 on the affected side, combined with the perpendicular needling at bilateral BL62. Besides, on the affected side, the penetrating needling was applied from Yangbai (GB14) toward four directions, named Shangxing (GV23), Touwei (ST8), Cuanzu (BL2) and Sizukong (TE23), the mutual penetrating needling was adopted between Dicang (ST4) and Jiache (ST6). Between Yingxiang (LI20) and Xiaguan (ST7), a row-arranged needling technique was applied. All of the needles were retained for 10 to 30 min in each treatment. The treatment was given once daily and the treatment for 10 days was as 1 course. A total of 2 courses of treatment were required. In the control group, prednisone acetate (30 mg/d), was administered consecutively for 5 days. Afterward, the dose was reduced to be 10 mg/d and the medication stopped after taking consecutively for 1 week. Muscular injection with vitamin B
    Results: The total effective rate of treatment group was 96.9 % (31/32), better than 84.4%(27/32) in the control group (
    Conclusion: The treatment with the penetrating needling at Cuanzhu (BL2) and Yuyao (EX-HN4) combined with the perpendicular needling at Shenmai (BL62) greatly promotes the recovery of orbicularis oculi muscle in the patients with facial neuritis, reduces the complications and presents the satisfactory clinical effect.
    MeSH term(s) Acupuncture Points ; Acupuncture Therapy ; Drug Combinations ; Drugs, Chinese Herbal ; Facial Paralysis/therapy ; Humans ; Tolnaftate
    Chemical Substances Drug Combinations ; Drugs, Chinese Herbal ; fructus schizandrae, radix ginseng, radix ophiopogonis drug combination ; Tolnaftate (06KB629TKV)
    Language Chinese
    Publishing date 2020-10-08
    Publishing country China
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1283179-7
    ISSN 1000-0607
    ISSN 1000-0607
    DOI 10.13702/j.1000-0607.190894
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Potential distribution of Notopterygium incisum Ting ex H. T. Chang and its predicted responses to climate change based on a comprehensive habitat suitability model

    Zefang Zhao / Yanlong Guo / Haiyan Wei / Qiao Ran / Jing Liu / Quanzhong Zhang / Wei Gu

    Ecology and Evolution, Vol 10, Iss 6, Pp 3004-

    2020  Volume 3016

    Abstract: Abstract Notopterygium incisum Ting ex H. T. Chang is a rare and endangered ...

    Abstract Abstract Notopterygium incisum Ting ex H. T. Chang is a rare and endangered traditional Chinese medicinal plant. In this research, we built a comprehensive habitat suitability (CHS) model to analyze the potential suitable habitat distribution of this species in the present and future in China. First, using nine different algorithms, we built an ensemble model to explore the possible impacts of climate change on the habitat distribution of this species. Then, based on this model, we built a CHS model to further identify the distribution characteristics of N. incisum‐suitable habitats in three time periods (current, 2050s, and 2070s) while considering the effects of soil and vegetation conditions. The results indicated that the current suitable habitat for N. incisum covers approximately 83.76 × 103 km2, and these locations were concentrated in the Tibet Autonomous Region, Gansu Province, Qinghai Province, and Sichuan Province. In the future, the areas of suitable habitat for N. incisum would significantly decrease and would be 69.53 × 103 km2 and 60.21 × 103 km2 in the 2050s and 2070s, respectively. However, the area of marginally suitable habitat would remain relatively stable. This study provides a more reliable and comprehensive method for modelling the current and future distributions of N. incisum, and it provides valuable insights for highlighting priority areas for medicinal plant conservation and resource utilization.
    Keywords climate change ; ensemble model ; Notopterygium incisum Ting ex H. T. Chang ; potential distribution ; species distribution models ; Ecology ; QH540-549.5
    Subject code 333
    Language English
    Publishing date 2020-03-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  5. Book: Ting ge xue han yu

    Liu, Delian

    = Learn Chinese through Music

    2007  

    Author's details Liu Delian
    Language Chinese
    Size 179 S., ill
    Publisher Shi jie tu shu chu ban gong si Beijing gong si
    Publishing place Beijing
    Document type Book
    Accompanying material 1 CD
    ISBN 9787506293006 ; 7506293005
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

  6. Book: Ting ge xue han yu

    Liu, Delian

    = Learn Chinese through Music

    2007  

    Author's details Liu Delian
    Language Chinese
    Size 141 S., ill
    Publisher Shi jie tu shu chu ban gong si Beijing gong si
    Publishing place Beijing
    Document type Book
    Accompanying material 1 CD
    ISBN 9787506286879 ; 7506286874
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

  7. Book: Ting ge xue han yu

    Liu, Delian

    Learn Chinese through Music

    2007  

    Author's details Liu Delian
    Language Chinese
    Publisher Shi jie tu shu chu ban gong si Beijing gong si
    Publishing place Beijing
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

  8. Book ; Audio / Video: Ma bei shang de fa ting

    Liu, Jie

    Courthouse on the horseback

    2006  

    Author's details [Regie: Liu Jie]
    Language Chinese
    Size 1 DVD (Region 1-8), 101 Min
    Publishing place China
    Document type Book ; Audio / Video
    Note Audiosprache: Chinesisch ; Untertitel: Chinesisch (Kurzzeichen), Englisch, Italienisch
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

  9. Book ; Audio / Video: Chen mo he mei ting

    Liu, Hao

    Chen Mo and Mei Ting

    2002  

    Author's details [Regie: Liu Hao]
    Language Chinese
    Size 1 DVD (Region 1-8), 75 Min
    Publishing place China
    Document type Book ; Audio / Video
    Note Audiosprache: Chinesisch ; Untertitel: Chinesisch (Kurzzeichen)
    Database Former special subject collection: coastal and deep sea fishing

    More links

    Kategorien

  10. Article ; Online: Exploring the mechanism of Tingli Pill in the treatment of HFpEF based on network pharmacology and molecular docking.

    Chi, Kuo / Yang, Saisai / Zhang, Yao / Zhao, Yongfa / Zhao, Jiahe / Chen, Qiuhan / Ge, Yuan / Liu, Jing

    Medicine

    2024  Volume 103, Issue 16, Page(s) e37727

    Abstract: To explore the mechanism of action of Tingli Pill (TLP) in the treatment of heart failure ...

    Abstract To explore the mechanism of action of Tingli Pill (TLP) in the treatment of heart failure with preserved ejection fraction (HFpEF) by using network pharmacology and molecular docking technology. The active components and targets of TLP were screened using the TCMSP and UniProt databases. HFpEF-related targets were identified using the OMIM and GeneCards databases. Drug-disease intersection targets were obtained via Venny 2.1.0, as well as establishing the "component-target" network and screening out the core active components. Construct a protein-protein interaction network of intersecting targets using the STRING database as well as Cytoscape software and filter the core targets. Gene ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analysis of core targets were performed using the Metascape database. The core active components of TLP for HFpEF were quercetin, kaempferol, β-sitosterol, isorhamnetin and hederagenin. The core targets of TLP for HFpEF were JUN, MAPK1, TP53, AKT1, RELA, TNF, MAPK14, and IL16. Gene ontology enrichment analysis obtained 1528 biological processes, 85 cell components, and 140 molecular functions. The Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis yielded 1940 signaling pathways, mainly involved in lipid and atherosclerosis, regulation of apoptotic signaling pathway, PI3K-Akt signaling pathway, HIF-1 signaling pathway, oxidative stress, TNF signaling pathway, and IL-17 signaling pathway. TLP has the characteristics of multi-component, multi-target, and multi-pathway in the treatment of HFpEF. This study lays the foundation for revealing the pharmacodynamic substances and mechanism of TLP in the treatment of HFpEF.
    MeSH term(s) Humans ; Molecular Docking Simulation ; Network Pharmacology ; Heart Failure/drug therapy ; Phosphatidylinositol 3-Kinases ; Stroke Volume ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use
    Chemical Substances Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Drugs, Chinese Herbal
    Language English
    Publishing date 2024-04-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000037727
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top