LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 23

Search options

  1. Article ; Online: Pediatric Cavernous Sinus Thrombosis and COVID-19 Infection: Case Report.

    Oragui, Chika / Gonzalez, Lisandra / Agha, Rabia

    Clinical pediatrics

    2023  Volume 62, Issue 12, Page(s) 1461–1464

    MeSH term(s) Humans ; Child ; Cavernous Sinus Thrombosis/diagnostic imaging ; Cavernous Sinus Thrombosis/therapy ; COVID-19/complications ; Anti-Bacterial Agents/therapeutic use ; Tomography, X-Ray Computed ; Sinus Thrombosis, Intracranial/diagnostic imaging ; Sinus Thrombosis, Intracranial/drug therapy
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-03-15
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207678-0
    ISSN 1938-2707 ; 0009-9228
    ISSN (online) 1938-2707
    ISSN 0009-9228
    DOI 10.1177/00099228231161024
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Delayed Seasonal RSV Surge Observed During the COVID-19 Pandemic.

    Agha, Rabia / Avner, Jeffrey R

    Pediatrics

    2021  Volume 148, Issue 3

    MeSH term(s) COVID-19 ; Humans ; Pandemics ; SARS-CoV-2 ; Seasons
    Language English
    Publishing date 2021-06-09
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 207677-9
    ISSN 1098-4275 ; 0031-4005
    ISSN (online) 1098-4275
    ISSN 0031-4005
    DOI 10.1542/peds.2021-052089
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: Intravenous immunoglobulin treatment of congenital parvovirus B19 induced anemia - a case report.

    Aronson, Stephanie T / Celiker, Mahmut Y / Guarini, Ludovico / Agha, Rabia

    Maternal health, neonatology and perinatology

    2023  Volume 9, Issue 1, Page(s) 10

    Abstract: Background: Parvovirus is a common childhood infection that could be very dangerous to the fetus, if pregnant women become infected. The spectrum of effects range from pure red blood cell aplasia with hydrops fetalis to meningoencephalitis, with many ... ...

    Abstract Background: Parvovirus is a common childhood infection that could be very dangerous to the fetus, if pregnant women become infected. The spectrum of effects range from pure red blood cell aplasia with hydrops fetalis to meningoencephalitis, with many symptoms in between. Severe anemia in the setting of pure red blood cell aplasia is one of the more common effects that neonatal experience (if infected intrapartum), with the current gold standard treatment being intrauterine or postnatal packed red blood cell (PRBC) transfusions, yet intravenous immunoglobulin (IVIG) may be a superior treatment option.
    Case presentation: A preterm infant was born at 26th week of gestational age via emergency Cesarean section due to hydrops fetalis, with parvovirus B19 exposure one month prior. The infant tested positive for IgM antibodies against parvovirus B19. Among many other serious complications of both hydrops fetalis and premature delivery, the infant had severe unremitting anemia, and received many PRBC transfusion over the course of his 71-day-long neonatal intensive care unit stay. During a follow up appointments as outpatient, his blood tests showed persistent high copies of parvovirus B19. He was then supported with PRBC transfusions and treated with IVIG. After three doses of IVIG, the infant's parvovirus B19 viral copy numbers have dramatically reduced and the infant did not require any more PRBC transfusions.
    Conclusions: IVIG infusion effectively treated the parvovirus B19 infection and restored erythropoiesis making the child transfusion independent. Furthermore, since IVIG is safe and readily crosses the placenta, further studies are needed to determine if IVIG should be considered as an alternative prenatal treatment for congenital parvovirus B19 infection.
    Language English
    Publishing date 2023-08-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2809925-4
    ISSN 2054-958X
    ISSN 2054-958X
    DOI 10.1186/s40748-023-00164-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Streptococcus pneumoniae meningitis in a child with idiopathic nephrotic syndrome: a case report.

    Guernsey, David / Arun, Aparna / Agha, Rabia / Kupferman, Juan C

    Journal of medical case reports

    2022  Volume 16, Issue 1, Page(s) 403

    Abstract: Background: Children with nephrotic syndrome are at increased risk of infections, including bacterial peritonitis, pneumonia, and cellulitis. However, bacterial meningitis, a potentially life-threatening complication, has not been highlighted as an ... ...

    Abstract Background: Children with nephrotic syndrome are at increased risk of infections, including bacterial peritonitis, pneumonia, and cellulitis. However, bacterial meningitis, a potentially life-threatening complication, has not been highlighted as an infectious complication of nephrotic syndrome in recent reviews. We report a very subtle and unusual presentation of bacterial meningitis in a child with nephrotic syndrome, which without a high index of suspicion, would have been missed.
    Case presentation: A 9-year-old African-American male with a history of steroid-dependent nephrotic syndrome presented to the nephrology clinic for routine follow-up. His medications included mycophenolate mofetil and alternate-day steroids. His only complaint was neck pain and stiffness that the mother attributed to muscle tightness relieved by massage. There was no history of fever, vomiting, headache, photophobia, or altered mental status. On physical examination, he was afebrile (99 °F), but had mild periorbital swelling and edema on lower extremities. He appeared ill and exhibited neck rigidity, and demonstrated reflex knee flexion when the neck was bent. Laboratory evaluation revealed leukocytosis, elevated C-reactive protein, hypoalbuminemia, and proteinuria. Cerebrospinal fluid suggested bacterial meningitis. The patient was treated with ceftriaxone and vancomycin. Both cerebrospinal and blood cultures grew Streptococcus pneumoniae; vancomycin was discontinued. The child completed a 2-week course of ceftriaxone and was discharged home.
    Conclusions: A high index of suspicion is necessary in children with nephrotic syndrome treated with corticosteroids, as symptoms may be masked, and thus, a life-threatening disease be missed. Bacterial meningitis should be highlighted as a serious infection complication in children with nephrotic syndrome.
    MeSH term(s) Child ; Male ; Humans ; Meningitis, Pneumococcal/complications ; Nephrotic Syndrome/complications ; Nephrotic Syndrome/drug therapy ; Ceftriaxone/therapeutic use ; Vancomycin/therapeutic use ; Meningitis, Bacterial/complications ; Meningitis, Bacterial/diagnosis ; Meningitis, Bacterial/drug therapy
    Chemical Substances Ceftriaxone (75J73V1629) ; Vancomycin (6Q205EH1VU)
    Language English
    Publishing date 2022-11-07
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-022-03648-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Streptococcus pneumoniae meningitis in a child with idiopathic nephrotic syndrome

    David Guernsey / Aparna Arun / Rabia Agha / Juan C. Kupferman

    Journal of Medical Case Reports, Vol 16, Iss 1, Pp 1-

    a case report

    2022  Volume 5

    Abstract: Abstract Background Children with nephrotic syndrome are at increased risk of infections, including bacterial peritonitis, pneumonia, and cellulitis. However, bacterial meningitis, a potentially life-threatening complication, has not been highlighted as ... ...

    Abstract Abstract Background Children with nephrotic syndrome are at increased risk of infections, including bacterial peritonitis, pneumonia, and cellulitis. However, bacterial meningitis, a potentially life-threatening complication, has not been highlighted as an infectious complication of nephrotic syndrome in recent reviews. We report a very subtle and unusual presentation of bacterial meningitis in a child with nephrotic syndrome, which without a high index of suspicion, would have been missed. Case presentation A 9-year-old African-American male with a history of steroid-dependent nephrotic syndrome presented to the nephrology clinic for routine follow-up. His medications included mycophenolate mofetil and alternate-day steroids. His only complaint was neck pain and stiffness that the mother attributed to muscle tightness relieved by massage. There was no history of fever, vomiting, headache, photophobia, or altered mental status. On physical examination, he was afebrile (99 °F), but had mild periorbital swelling and edema on lower extremities. He appeared ill and exhibited neck rigidity, and demonstrated reflex knee flexion when the neck was bent. Laboratory evaluation revealed leukocytosis, elevated C-reactive protein, hypoalbuminemia, and proteinuria. Cerebrospinal fluid suggested bacterial meningitis. The patient was treated with ceftriaxone and vancomycin. Both cerebrospinal and blood cultures grew Streptococcus pneumoniae; vancomycin was discontinued. The child completed a 2-week course of ceftriaxone and was discharged home. Conclusions A high index of suspicion is necessary in children with nephrotic syndrome treated with corticosteroids, as symptoms may be masked, and thus, a life-threatening disease be missed. Bacterial meningitis should be highlighted as a serious infection complication in children with nephrotic syndrome.
    Keywords Infection ; Central nervous system ; Kidney ; Pediatric ; Meningeal ; Medicine ; R
    Subject code 572
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  6. Article ; Online: Acute Oral Mucositis During Hypo-Fractionated Radiation in Squamous Cell Carcinoma of Oral Cavity.

    Hammad, Agha Muhammad / Abrar, Sehrish / Tahseen, Rabia / Qureshi, Bilal Mazhar / Hafiz, Asim / Abbasi, Ahmed Nadeem

    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

    2023  Volume 33, Issue 12, Page(s) 1460–1462

    Abstract: Oral mucositis remains a concern in the treatment of head and neck malignancies. This small study included 11 patients treated by hypo-fractionated radiotherapy and assessed for oral mucositis. All patients received a radiation dose of 55 Gy in 20 ... ...

    Abstract Oral mucositis remains a concern in the treatment of head and neck malignancies. This small study included 11 patients treated by hypo-fractionated radiotherapy and assessed for oral mucositis. All patients received a radiation dose of 55 Gy in 20 fractions (2.75 Gy/fraction). At the end of the first week of radiation, three patients had Grade I oral mucositis. During the last week of radiation, most of the patients developed Grade II and III mucositis, 7 (64%) and 4 (36%), respectively. At one month follow-up, 5 (46%) of them had Grade I, while 2 (18%) had developed Grade II mucositis. At three months, 2 (18%) had Grade I mucositis, and none of the patients showed Grade II/III oral mucositis. Grade II oral mucositis was the most common grade found mainly in the last week of radiation therapy. None had Grade IV oral mucositis. Key Words: Acute oral mucositis, Hypo-fractioned radiation, Oral carcinoma.
    MeSH term(s) Humans ; Mucositis/etiology ; Carcinoma, Squamous Cell/radiotherapy ; Carcinoma, Squamous Cell/pathology ; Head and Neck Neoplasms/radiotherapy ; Stomatitis/etiology ; Stomatitis/drug therapy
    Language English
    Publishing date 2023-12-01
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 2276646-7
    ISSN 1681-7168 ; 1022-386X
    ISSN (online) 1681-7168
    ISSN 1022-386X
    DOI 10.29271/jcpsp.2023.12.1460
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Apnea, Cyanosis, and Septic Shock in a Term Neonate.

    Lee, Gloria / Swaney, Nicole / Avner, Jeffrey R / Agha, Rabia

    Global pediatric health

    2019  Volume 6, Page(s) 2333794X19851416

    Language English
    Publishing date 2019-06-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2785531-4
    ISSN 2333-794X ; 2333-794X
    ISSN (online) 2333-794X
    ISSN 2333-794X
    DOI 10.1177/2333794X19851416
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Initial Observations of COVID-19 in US Children.

    Agha, Rabia / Kojaoghlanian, Tsoline / Avner, Jeffrey R

    Hospital pediatrics

    2020  Volume 10, Issue 10, Page(s) 902–905

    Abstract: Coronavirus disease (COVID-19) has affected children differently from adults worldwide. Data on the clinical presentation of the infection in children are limited. We present a detailed account of pediatric inpatients infected with severe acute ... ...

    Abstract Coronavirus disease (COVID-19) has affected children differently from adults worldwide. Data on the clinical presentation of the infection in children are limited. We present a detailed account of pediatric inpatients infected with severe acute respiratory syndrome coronavirus 2 virus at our institution during widespread local transmission, aiming to understand disease presentation and outcomes. A retrospective chart review was performed of children, ages 0 to 18 years, with a positive polymerase chain reaction test for severe acute respiratory syndrome coronavirus 2 on nasopharyngeal specimens admitted to our hospital over a 4-week period. We present clinical data from 22 patients and highlight the variability of the presentation. In our study, most children presented without respiratory illness or symptoms suggestive of COVID-19; many were identified only because of universal testing. Because children may have variable signs and symptoms of COVID-19 infection, targeted testing may miss some cases.
    MeSH term(s) Adolescent ; Age Distribution ; Alanine Transaminase/metabolism ; Aspartate Aminotransferases/metabolism ; Betacoronavirus ; C-Reactive Protein/metabolism ; COVID-19 ; COVID-19 Testing ; Child ; Child, Preschool ; Chronic Disease ; Clinical Laboratory Techniques ; Comorbidity ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/metabolism ; Coronavirus Infections/physiopathology ; Coronavirus Infections/therapy ; Cough/physiopathology ; Dyspnea/physiopathology ; Fatigue/physiopathology ; Female ; Fever/physiopathology ; Heart Diseases/epidemiology ; Hospitalization ; Hospitals, Pediatric ; Humans ; Infant ; Infant, Newborn ; Lung Diseases/epidemiology ; Lymphopenia/epidemiology ; Male ; Mass Screening ; Neoplasms/epidemiology ; New York City/epidemiology ; Noninvasive Ventilation ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/therapy ; Procalcitonin/metabolism ; Respiration, Artificial ; Retrospective Studies ; SARS-CoV-2 ; Seizures/physiopathology ; Sex Distribution ; United States
    Chemical Substances Procalcitonin ; C-Reactive Protein (9007-41-4) ; Aspartate Aminotransferases (EC 2.6.1.1) ; Alanine Transaminase (EC 2.6.1.2)
    Keywords covid19
    Language English
    Publishing date 2020-07-07
    Publishing country United States
    Document type Journal Article
    ISSN 2154-1671
    ISSN (online) 2154-1671
    DOI 10.1542/hpeds.2020-000257
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Abscopal Effect: An Old Concept with a New Horizon.

    Abbasi, Ahmed Nadeem / Hammad Khan, Agha Muhammad / Mansha, Muhammad Atif / Shaukat, Fatima / Tahseen, Rabia

    The Gulf journal of oncology

    2022  Volume 1, Issue 36, Page(s) 60–66

    Abstract: Abscopal effect is defined as a phenomenon where radiation delivery at one site induces shrinkage of disease at a distant site, outside the radiation field. Although it is an old concept but with recent advancements in the fields of diagnostic and ... ...

    Abstract Abscopal effect is defined as a phenomenon where radiation delivery at one site induces shrinkage of disease at a distant site, outside the radiation field. Although it is an old concept but with recent advancements in the fields of diagnostic and therapeutic oncology, this effect has gained popularity and nowadays has become an area of interest for the researchers.With the current success of immunotherapy, there is robust and interesting data looming to evaluate potential synergistic effect of radiation coupled with immunotherapy to attain abscopal effect. Our article highlights background, mechanism and a brief literature review for abscopal response in conjunction with immunotherapy. Keywords: Abscopal Effect, Radiation, Immunotherapy, Personalized Medicine.
    MeSH term(s) Humans ; Immunotherapy ; Radiotherapy
    Language English
    Publishing date 2022-01-10
    Publishing country Kuwait
    Document type Journal Article
    ISSN 2078-2101
    ISSN 2078-2101
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Encephalitis Associated with COVID-19 Infection in an 11-Year-Old Child.

    McAbee, Gary N / Brosgol, Yuri / Pavlakis, Steven / Agha, Rabia / Gaffoor, Mohamed

    Pediatric neurology

    2020  Volume 109, Page(s) 94

    MeSH term(s) COVID-19 ; Child ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Encephalitis, Viral/diagnosis ; Encephalitis, Viral/etiology ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Status Epilepticus/diagnosis ; Status Epilepticus/etiology
    Keywords covid19
    Language English
    Publishing date 2020-04-24
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 639164-3
    ISSN 1873-5150 ; 0887-8994
    ISSN (online) 1873-5150
    ISSN 0887-8994
    DOI 10.1016/j.pediatrneurol.2020.04.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top