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Article ; Online: Case 297: Mucinous Adenocarcinoma of the Prostate.

Kanas, Alexandre Fligelman / Fenelon, Sandro Santos / Santos, João Manoel Miranda Magalhães / Coelho, Rafael Ferreira / Guglielmetti, Giuliano Betoni / Nahas, William Carlos / Viana, Publio Cesar Cavalcante

Radiology

2021 Volume 302, Issue 1, Page(s) 238–242

Abstract: History A 70-year-old man was referred to our institution with chronic obstructive urinary symptoms and constipation for 2 years before admission. His medical history was unremarkable. Outside laboratory tests revealed an elevated serum prostate-specific ...

Abstract	History A 70-year-old man was referred to our institution with chronic obstructive urinary symptoms and constipation for 2 years before admission. His medical history was unremarkable. Outside laboratory tests revealed an elevated serum prostate-specific antigen level (21.7 ng/mL [normal range, 0.00-4.00 ng/mL]), and urinalysis results were negative. He was admitted for evaluation of possible prostate cancer. The patient reported no specific symptoms of infection and denied fever, dysuria, hematuria, and abdominal pain. He had no family history of prostate cancer. On physical examination, he was afebrile, and the digital rectal examination was not painful. These findings were evidence of an enlarged prostate and a hard multilobulated mass, which was palpable bilaterally. The urologic team performed MRI of the prostate.
MeSH term(s)	Adenocarcinoma, Mucinous/diagnostic imaging ; Aged ; Diagnosis, Differential ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Prostate/diagnostic imaging ; Prostatic Neoplasms/diagnostic imaging
Language	English
Publishing date	2021-12-20
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	80324-8
ISSN	1527-1315 ; 0033-8419
ISSN (online)	1527-1315
ISSN	0033-8419
DOI	10.1148/radiol.202949
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Article ; Online: Case 297.

Radiology

2021 Volume 300, Issue 3, Page(s) 725–729

Abstract	History A 70-year-old man was referred to our institution with chronic obstructive urinary symptoms and constipation for 2 years before admission. His medical history was unremarkable. Outside laboratory tests revealed an elevated serum prostate-specific antigen level (21.7 ng/mL [normal range, 0.00-4.00 ng/mL]), and urinalysis results were negative. He was admitted for evaluation of possible prostate cancer. The patient reported no specific symptoms of infection and denied fever, dysuria, hematuria, and abdominal pain. He had no family history of prostate cancer. On physical examination, he was afebrile, and the digital rectal examination was not painful. These findings were evidence of an enlarged prostate and a hard multilobulated mass, which was palpable bilaterally. The urologic team performed MRI of the prostate (Figs 1-4).
Language	English
Publishing date	2021-08-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	80324-8
ISSN	1527-1315 ; 0033-8419
ISSN (online)	1527-1315
ISSN	0033-8419
DOI	10.1148/radiol.2021202948
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Article ; Online: Intimointimal Intussusception in Acute Aortic Dissection.

Gomes de Farias, Lucas de Pádua / Santos, João Manoel Miranda Magalhães / Teles, Gustavo Borges da Silva / Baptista, Luciana de Pádua Silva

Radiology. Cardiothoracic imaging

2020 Volume 2, Issue 4, Page(s) e200023

Language	English
Publishing date	2020-08-27
Publishing country	United States
Document type	Journal Article
ISSN	2638-6135
ISSN (online)	2638-6135
DOI	10.1148/ryct.2020200023
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Initial Results of the Use of a Standardized Diagnostic Criteria for Chest Computed Tomography Findings in Coronavirus Disease 2019.

Miranda Magalhães Santos, João Manoel / Paula Alves Fonseca, Ana / Pinheiro Zarattini Anastacio, Eduardo / Formagio Minenelli, Fernanda / Furtado de Albuquerque Cavalcanti, Conrado / Borges da Silva Teles, Gustavo

Journal of computer assisted tomography

2020 Volume 44, Issue 5, Page(s) 647–651

Abstract: Objective: The objective of this study was to assess the initial results of chest computed tomography (CT) standardized diagnostic criteria proposed by the Radiological Society of North America in coronavirus disease 2019 (COVID-19) compared with ... ...

Abstract	Objective: The objective of this study was to assess the initial results of chest computed tomography (CT) standardized diagnostic criteria proposed by the Radiological Society of North America in coronavirus disease 2019 (COVID-19) compared with reverse transcription-polymerase chain reaction (RT-PCR). Methods: Seventy-one patients who underwent RT-PCR test for COVID-19 and chest CT within an interval of 4 days or less were included. Seventy-five CTs were reviewed and classified as typical, indeterminate, or atypical appearance or negative for pneumonia by 2 radiologists. With RT-PCR as reference standard, the performance of the CT diagnostic criteria in diagnosing COVID-19 was assessed. Results: The prevalence of positive RT-PCR was 45.1%. It was obtained a sensitivity of 83% (95% confidence interval [CI], 78%-89%), a specificity of 97% (95% CI, 92%-99%), an accuracy of 91% (95% CI, 85%-96%), a positive predictive value of 97% (95% CI, 91%-99%), and a negative predictive value of 86% (95% CI, 80%-92%). The diagnostic performance was excellent, considering the area under the curve of 0.92 (95% CI, 0.84-0.99). Conclusions: Chest CT standardized diagnostic criteria had high specificity and positive predictive value for the diagnosis of COVID-19 when presenting a typical appearance.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Child ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Female ; Humans ; Lung/diagnostic imaging ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/diagnosis ; Radiography, Thoracic/methods ; Retrospective Studies ; SARS-CoV-2 ; Sensitivity and Specificity ; Tomography, X-Ray Computed/methods ; Young Adult
Keywords	covid19
Language	English
Publishing date	2020-07-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	80392-3
ISSN	1532-3145 ; 0363-8715
ISSN (online)	1532-3145
ISSN	0363-8715
DOI	10.1097/RCT.0000000000001054
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Article ; Online: State-of-the-art in radiomics of hepatocellular carcinoma: a review of basic principles, applications, and limitations.

Miranda Magalhaes Santos, Joao Manoel / Clemente Oliveira, Brunna / Araujo-Filho, Jose de Arimateia Batista / Assuncao-Jr, Antonildes N / de M Machado, Felipe Augusto / Carlos Tavares Rocha, Camila / Horvat, Joao Vicente / Menezes, Marcos Roberto / Horvat, Natally

Abdominal radiology (New York)

2019 Volume 45, Issue 2, Page(s) 342–353

Abstract: Radiomics is a new field in medical imaging with the potential of changing medical practice. Radiomics is characterized by the extraction of several quantitative imaging features which are not visible to the naked eye from conventional imaging modalities, ...

Abstract	Radiomics is a new field in medical imaging with the potential of changing medical practice. Radiomics is characterized by the extraction of several quantitative imaging features which are not visible to the naked eye from conventional imaging modalities, and its correlation with specific relevant clinical endpoints, such as pathology, therapeutic response, and survival. Several studies have evaluated the use of radiomics in patients with hepatocellular carcinoma (HCC) with encouraging results, particularly in the pretreatment prediction of tumor biological characteristics, risk of recurrence, and survival. In spite of this, there are limitations and challenges to be overcome before the implementation of radiomics into clinical routine. In this article, we will review the concepts of radiomics and their current potential applications in patients with HCC. It is important that the multidisciplinary team involved in the treatment of patients with HCC be aware of the basic principles, benefits, and limitations of radiomics in order to achieve a balanced interpretation of the results toward a personalized medicine.
MeSH term(s)	Biomarkers, Tumor/analysis ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/pathology ; Humans ; Image Interpretation, Computer-Assisted/methods ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/pathology
Chemical Substances	Biomarkers, Tumor
Language	English
Publishing date	2019-11-07
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2839786-1
ISSN	2366-0058 ; 2366-004X
ISSN (online)	2366-0058
ISSN	2366-004X
DOI	10.1007/s00261-019-02299-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Abdominal gastrointestinal imaging findings on computed tomography in patients with COVID-19 and correlation with clinical outcomes.

Horvat, Natally / Pinto, Paulo Victor Alves / Araujo-Filho, Jose de Arimateia Batista / Santos, João Manoel Miranda Magalhaes / Dias, Adriano Basso / Miranda, Júlia Azevedo / de Oliveira, Camila Vilela / Barbosa, Camila Silva / Morais, Thamara Carvalho / N Assuncao-Jr, Antonildes / Nomura, César Higa / Viana, Publio Cesar Cavalcante

European journal of radiology open

2021 Volume 8, Page(s) 100326

Abstract: Purpose: Pulmonary imaging finding of Coronavirus disease 2019 (COVID-19) has been widely described, but until now few studies have been published about abdominal radiological presentation. The aim of this study was to provide an overview of abdominal ... ...

Abstract	Purpose: Pulmonary imaging finding of Coronavirus disease 2019 (COVID-19) has been widely described, but until now few studies have been published about abdominal radiological presentation. The aim of this study was to provide an overview of abdominal imaging findings in patients with COVID-19 in a multicenter study and correlate them with worse clinical outcomes. Materials and methods: This retrospective study included adult COVID-positive patients with abdominal CT performed from 4/1/2020 to 5/1/2020 from two institutions. Demographic, laboratory and clinical data were recorded, including clinical outcomes. Results: Of 81 COVID-positive patients, the average age was 61 years, 42 (52%) women and 45 (55%) had positive abdominopelvic findings. The most common abdominal imaging features were intestinal imaging findings (20/81, 24%), including colorectal (4/81, 5%) and small bowel thickening (10/81, 12%), intestinal distension (15/81, 18%), pneumatosis (1/81, 1%) and intestinal perforation (1/81, 1%). On multivariate analysis, intestinal imaging findings were associated with higher risk of worse outcome (death or invasive mechanical ventilation) (RR = 2.6, p = 0.04) and higher risk of invasive mechanical ventilation alone (RR = 6.2, p = 0.05). Conclusion: Intestinal abnormalities were common findings in COVID-19 patients who underwent abdominal CT and were significantly correlated to worse outcomes in the clinical follow-up.
Language	English
Publishing date	2021-01-18
Publishing country	England
Document type	Journal Article
ZDB-ID	2810314-2
ISSN	2352-0477
ISSN	2352-0477
DOI	10.1016/j.ejro.2021.100326
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Article: Anatomical variations and congenital anomalies of the ribs revisited by multidetector computed tomography.

de Farias, Lucas de Pádua Gomes / Menezes, Daniel Cunha / Faé, Igor Schneider / de Arruda, Pedro Henrique Coelho / Santos, João Manoel Miranda Magalhães / Teles, Gustavo Borges da Silva

Radiologia brasileira

2020 Volume 53, Issue 6, Page(s) 413–418

Abstract: As they are asymptomatic or have a nonspecific, anatomical variations of the ribs are usually detected as incidental findings on imaging studies. They may be isolated changes or can be related to anomalies or clinical syndromes. Such variations are ... ...

Abstract	As they are asymptomatic or have a nonspecific, anatomical variations of the ribs are usually detected as incidental findings on imaging studies. They may be isolated changes or can be related to anomalies or clinical syndromes. Such variations are easily overlooked on conventional radiography and computed tomography if they are not actively investigated, mainly because most indications for a chest X-ray studies aim to evaluate the lung parenchyma and mediastinal structures. The objective of this pictorial essay was to use multislice computed tomography images to illustrate the imaging aspects of the main anatomical variations and congenital anomalies of the ribs.
Language	English
Publishing date	2020-02-26
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2078806-X
ISSN	1678-7099 ; 0100-3984
ISSN (online)	1678-7099
ISSN	0100-3984
DOI	10.1590/0100-3984.2019.0131
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Anatomical variations and congenital anomalies of the ribs revisited by multidetector computed tomography

Lucas de Pádua Gomes de Farias / Daniel Cunha Menezes / Igor Schneider Faé / Pedro Henrique Coelho de Arruda / João Manoel Miranda Magalhães Santos / Gustavo Borges da Silva Teles

Radiologia Brasileira, Vol 53, Iss 6, Pp 413-

2020 Volume 418

Abstract: Abstract As they are asymptomatic or have a nonspecific, anatomical variations of the ribs are usually detected as incidental findings on imaging studies. They may be isolated changes or can be related to anomalies or clinical syndromes. Such variations ... ...

Abstract	Abstract As they are asymptomatic or have a nonspecific, anatomical variations of the ribs are usually detected as incidental findings on imaging studies. They may be isolated changes or can be related to anomalies or clinical syndromes. Such variations are easily overlooked on conventional radiography and computed tomography if they are not actively investigated, mainly because most indications for a chest X-ray studies aim to evaluate the lung parenchyma and mediastinal structures. The objective of this pictorial essay was to use multislice computed tomography images to illustrate the imaging aspects of the main anatomical variations and congenital anomalies of the ribs.
Keywords	Ribs ; Anatomical variation ; Multislice computed tomography ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Language	English
Publishing date	2020-11-01T00:00:00Z
Publisher	Colégio Brasileiro de Radiologia e Diagnóstico por Imagem
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Abdominal gastrointestinal imaging findings on computed tomography in patients with COVID-19 and correlation with clinical outcomes

Natally Horvat / Paulo Victor Alves Pinto / Jose de Arimateia Batista Araujo-Filho / João Manoel Miranda Magalhaes Santos / Adriano Basso Dias / Júlia Azevedo Miranda / Camila Vilela de Oliveira / Camila Silva Barbosa / Thamara Carvalho Morais / Antonildes N Assuncao-Jr / César Higa Nomura / Publio Cesar Cavalcante Viana

European Journal of Radiology Open, Vol 8, Iss , Pp 100326- (2021)

2021

Abstract	Purpose: Pulmonary imaging finding of Coronavirus disease 2019 (COVID-19) has been widely described, but until now few studies have been published about abdominal radiological presentation. The aim of this study was to provide an overview of abdominal imaging findings in patients with COVID-19 in a multicenter study and correlate them with worse clinical outcomes. Materials and methods: This retrospective study included adult COVID-positive patients with abdominal CT performed from 4/1/2020 to 5/1/2020 from two institutions. Demographic, laboratory and clinical data were recorded, including clinical outcomes. Results: Of 81 COVID-positive patients, the average age was 61 years, 42 (52%) women and 45 (55%) had positive abdominopelvic findings. The most common abdominal imaging features were intestinal imaging findings (20/81, 24%), including colorectal (4/81, 5%) and small bowel thickening (10/81, 12%), intestinal distension (15/81, 18%), pneumatosis (1/81, 1%) and intestinal perforation (1/81, 1%). On multivariate analysis, intestinal imaging findings were associated with higher risk of worse outcome (death or invasive mechanical ventilation) (RR = 2.6, p = 0.04) and higher risk of invasive mechanical ventilation alone (RR = 6.2, p = 0.05). Conclusion: Intestinal abnormalities were common findings in COVID-19 patients who underwent abdominal CT and were significantly correlated to worse outcomes in the clinical follow-up.
Keywords	Coronavirus ; Computed tomography ; Patient-relevant outcome ; Radiology ; Infections ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	610
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Initial Results of the Use of a Standardized Diagnostic Criteria for Chest Computed Tomography Findings in Coronavirus Disease 2019

J Comput Assist Tomogr

Abstract: OBJECTIVE: The objective of this study was to assess the initial results of chest computed tomography (CT) standardized diagnostic criteria proposed by the Radiological Society of North America in coronavirus disease 2019 (COVID-19) compared with reverse ...

Abstract	OBJECTIVE: The objective of this study was to assess the initial results of chest computed tomography (CT) standardized diagnostic criteria proposed by the Radiological Society of North America in coronavirus disease 2019 (COVID-19) compared with reverse transcription-polymerase chain reaction (RT-PCR). METHODS: Seventy-one patients who underwent RT-PCR test for COVID-19 and chest CT within an interval of 4 days or less were included. Seventy-five CTs were reviewed and classified as typical, indeterminate, or atypical appearance or negative for pneumonia by 2 radiologists. With RT-PCR as reference standard, the performance of the CT diagnostic criteria in diagnosing COVID-19 was assessed. RESULTS: The prevalence of positive RT-PCR was 45.1%. It was obtained a sensitivity of 83% (95% confidence interval [CI], 78%-89%), a specificity of 97% (95% CI, 92%-99%), an accuracy of 91% (95% CI, 85%-96%), a positive predictive value of 97% (95% CI, 91%-99%), and a negative predictive value of 86% (95% CI, 80%-92%). The diagnostic performance was excellent, considering the area under the curve of 0.92 (95% CI, 0.84-0.99). CONCLUSIONS: Chest CT standardized diagnostic criteria had high specificity and positive predictive value for the diagnosis of COVID-19 when presenting a typical appearance.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #639451
Database	COVID19

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