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  1. Article ; Online: In Memoriam:Steven LeRoy Linder,MD(1945–2015).

    Elterman, Roy D

    Seminars in pediatric neurology

    2016  Volume 23, Issue 1, Page(s) 4–5

    MeSH term(s) History, 20th Century ; History, 21st Century ; Humans ; Neurology/history ; Pediatrics/history ; United States
    Language English
    Publishing date 2016-01-04
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article ; Portrait
    ZDB-ID 1290000-x
    ISSN 1558-0776 ; 1071-9091
    ISSN (online) 1558-0776
    ISSN 1071-9091
    DOI 10.1016/j.spen.2016.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Metformin-Induced Hemolysis in a Patient With Glucose-6-Phosphate Dehydrogenase Deficiency Presenting With Concurrent Idiopathic Steven-Johnson Syndrome/Toxic Epidermal Necrolysis.

    Roy Choudhury, Avijoy / Gadaga, Cecilia / Moodley, Layuren / Moodley, Aru

    Cureus

    2021  Volume 13, Issue 10, Page(s) e18506

    Abstract: ... presented with idiopathic Steven-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). Metformin causing ...

    Abstract Metformin is one of the most widely prescribed medications for type 2 diabetes. While extremely rare, metformin has been reported to cause hemolysis in patients with glucose-6-phosphate dehydrogenase deficiency. In this paper, we present a case of a patient with previously undiagnosed glucose-6-phosphate dehydrogenase deficiency who presented with hemolysis likely induced by metformin. The patient concurrently presented with idiopathic Steven-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). Metformin causing hemolysis is extremely rare but considering the severe outcomes, it is something that medical practitioners need to be aware of.
    Language English
    Publishing date 2021-10-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.18506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: In Memoriam: Steven LeRoy Linder, MD: May 8, 1945-June 10, 2015.

    Elterman, Roy D

    Pediatric neurology

    2015  Volume 53, Issue 6, Page(s) 471–472

    MeSH term(s) Headache/history ; History, 20th Century ; History, 21st Century ; Humans ; Neurology/history ; Pediatrics/history
    Language English
    Publishing date 2015-12
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 639164-3
    ISSN 1873-5150 ; 0887-8994
    ISSN (online) 1873-5150
    ISSN 0887-8994
    DOI 10.1016/j.pediatrneurol.2015.09.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Rezension] Kates, Steven, Say's law and the Keynesian revolution

    Rotheim, Roy J / Kates, Steven

    Journal of economic literature Vol. 37, No. 3 , p. 1178-1179

    Cheltenham [u.a.], Elgar, 1998

    1999  Volume 37, Issue 3, Page(s) 1178–1179

    Author's details [rezensiert von:] Roy J. Rotheim
    Keywords 40;49
    Language English
    Publisher Assoc.
    Publishing place Nashville, Tenn.
    Document type Article
    ZDB-ID 3076-4
    Database ECONomics Information System

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  5. Book ; Online: Age determination of hornblende in ODP Site 188-1165 and DSDP Hole 28-268, supplementary data to: Williams, Trevor; van de Flierdt, Tina; Hemming, Sidney R; Chung, Elena; Roy, Martin; Goldstein, Steven L (2010): Evidence for iceberg armadas from East Antarctica in the Southern Ocean during the late Miocene and early Pliocene. Earth and Planetary Science Letters, 290(3-4), 351-361

    Williams, Trevor / Chung, Elena / Goldstein, Steven L / Hemming, Sidney R / Roy, Martin / van de Flierdt, Tina

    2010  

    Abstract: Sediments from Ocean Drilling Program Site 1165 in the Indian Ocean sector of the Southern Ocean (off Prydz Bay) contain a series of layers that are rich in ice-rafted debris (IRD). Here we present evidence that IRD-rich layers at Site 1165 at 7, 4.8, ... ...

    Abstract Sediments from Ocean Drilling Program Site 1165 in the Indian Ocean sector of the Southern Ocean (off Prydz Bay) contain a series of layers that are rich in ice-rafted debris (IRD). Here we present evidence that IRD-rich layers at Site 1165 at 7, 4.8, and 3.5 Ma record short-lived, massive discharges of icebergs from Wilkes Land and Adélie Land, more than 1500 kilometers to the east of the depositional site. This distant source of icebergs is clearly defined by the presence of IRD hornblende grains with 40Ar/39Ar ages of 1200-1100 Ma and 1550-1500 Ma, ages that are not found on the East Antarctic continent in locations closer to Site 1165. This observation requires enormous amounts of detritus-carrying drifting icebergs, most likely in the form of large icebergs. These events probably reflect destabilization, surge, and break-up of ice streams on the Wilkes Land and Adélie Land margins of the East Antarctic Ice Sheet, in the vicinity of the low-lying Aurora and Wilkes Basins. They occurred under warming conditions, but each coast seems to have produced ice-rafting events independently, at different times. The data presented here constitute the first evidence of far-traveled icebergs from specific source areas around the East Antarctic perimeter. Launch of these icebergs may have happened during quite dramatic events, perhaps analogous to "Heinrich Events" in the North Atlantic.
    Language English
    Dates of publication 2010-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1016/j.epsl.2009.12.031
    DOI 10.1594/PANGAEA.786664
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  6. Article ; Online: Paroxysmal 2/1 atrioventricular block: do not pace! Why and what is the mechanism?

    Wansa, Nader / Vercauteren, Steven / De Roy, Luc

    Acta cardiologica

    2023  Volume 78, Issue 6, Page(s) 728–732

    MeSH term(s) Humans ; Atrioventricular Block/diagnosis ; Atrioventricular Block/etiology ; Atrioventricular Block/therapy ; Atrioventricular Node ; Electrocardiography ; Pacemaker, Artificial
    Language English
    Publishing date 2023-05-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 390197-x
    ISSN 1784-973X ; 0001-5385
    ISSN (online) 1784-973X
    ISSN 0001-5385
    DOI 10.1080/00015385.2023.2206293
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [SURGICAL TREATMENT VERSUS ENDOSCOPIC TREATMENT FOR ACHALASIA IN THE MODERN ERA].

    Apel, Roy / Amir-Barak, Hadar / Shamah, Steven / Wiesel, Ory

    Harefuah

    2024  Volume 163, Issue 1, Page(s) 43–49

    Abstract: Introduction: Achalasia is a disorder of esophageal motility characterized by absent relaxation of the lower esophageal sphincter and abnormal peristalsis of the esophagus during swallowing. The etiology is divided into primary idiopathic achalasia and ... ...

    Abstract Introduction: Achalasia is a disorder of esophageal motility characterized by absent relaxation of the lower esophageal sphincter and abnormal peristalsis of the esophagus during swallowing. The etiology is divided into primary idiopathic achalasia and secondary achalasia and classified into 3 subtypes based on manometric evaluation, according to the Chicago 4.0 classification. The goal of the therapy is symptomatic improvement and prevention of late complications. While there are several endoscopic therapies, the gold standard therapy is laparoscopic Heller myotomy. Since its debut in 2008, per-oral-endoscopic-myotomy (POEM) became an accepted treatment for achalasia with non-inferior short term outcomes compared to Heller myotomy. In the following review, we will explore the indications, guidelines, and controversies in the modern treatment of achalsia, focusing on the Heller myotomy versus POEM.
    MeSH term(s) Humans ; Esophageal Achalasia/surgery ; Treatment Outcome ; Endoscopy ; Esophageal Sphincter, Lower/surgery ; Manometry
    Language Hebrew
    Publishing date 2024-01-31
    Publishing country Israel
    Document type English Abstract ; Journal Article
    ZDB-ID 953872-0
    ISSN 0017-7768
    ISSN 0017-7768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: COVID related tracheostomy tube supply shortage and mitigation strategies for safe tracheotomy care in children.

    Rickert, Scott / Chi, David / Gerber, Mark / Roy, Soham / Sidell, Doug / Sobol, Steven E / Wei, Julie

    International journal of pediatric otorhinolaryngology

    2024  Volume 180, Page(s) 111943

    Language English
    Publishing date 2024-04-06
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 754501-0
    ISSN 1872-8464 ; 0165-5876
    ISSN (online) 1872-8464
    ISSN 0165-5876
    DOI 10.1016/j.ijporl.2024.111943
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Teaching Clinical Reasoning in the Preclinical Period.

    Mallory, Renee / Maciuba, Joseph M / Roy, Michael / Durning, Steven J

    Military medicine

    2023  

    Abstract: Introduction: Developing the clinical reasoning skills necessary to becoming an astute diagnostician is essential for medical students. While some medical schools offer longitudinal opportunities for students to practice clinical reasoning during the ... ...

    Abstract Introduction: Developing the clinical reasoning skills necessary to becoming an astute diagnostician is essential for medical students. While some medical schools offer longitudinal opportunities for students to practice clinical reasoning during the preclinical curriculum, there remains a paucity of literature fully describing what that curriculum looks like. As a result, medical educators struggle to know what an effective clinical reasoning curriculum should look like, how it should be delivered, how it should be assessed, or what faculty development is necessary to be successful. We present our Introduction to Clinical Reasoning course that is offered throughout the preclinical curriculum of the Uniformed Services University of the Health Sciences. The course introduces clinical reasoning through interactive lectures and 28 case-based small group activities over 15 months.The curriculum is grounded in script theory with a focus on diagnostic reasoning. Specific emphasis is placed on building the student's semantic competence, constructing problem lists, comparing and contrasting similar diagnoses, constructing a summary statement, and formulating a prioritized differential diagnosis the student can defend. Several complementary methods of assessment are utilized across the curriculum. These include assessments of participation, knowledge, and application. The course leverages clinical faculty, graduate medical education trainees, and senior medical students as small group facilitators. Feedback from students and faculty consistently identifies the course as a highly effective and engaging way to teach clinical reasoning.
    Conclusion: Our Introduction to Clinical Reasoning course offers students repeated exposure to well-selected cases to promote their development of clinical reasoning. The course is an example of how clinical reasoning can be taught across the preclinical curriculum without extensive faculty training in medical education or clinical reasoning theory. The course can be adapted into different instructional formats to cover a variety of topics to provide the early learner with sequential exposure and practice in diagnostic reasoning.
    Language English
    Publishing date 2023-09-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 391061-1
    ISSN 1930-613X ; 0026-4075
    ISSN (online) 1930-613X
    ISSN 0026-4075
    DOI 10.1093/milmed/usad370
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Selective binding of oxalate by a tris-ureido calix[6]tube in a protic environment.

    Lavendomme, Roy / Moerkerke, Steven / Mariaule, Gaëlle / Jabin, Ivan

    Organic & biomolecular chemistry

    2023  Volume 21, Issue 33, Page(s) 6730–6737

    Abstract: Due to their significant role in industry and biological systems, the interest in selectively recognizing and detecting small dicarboxylates has grown in recent years. In this study, we report on the binding properties of a family of tubular-shaped ... ...

    Abstract Due to their significant role in industry and biological systems, the interest in selectively recognizing and detecting small dicarboxylates has grown in recent years. In this study, we report on the binding properties of a family of tubular-shaped heterotritopic receptors based on bis-calix[6]arenes, which contain three (thio)urea bridges (C3U and C3TU) or six urea bridges (C6U), toward dicarboxylates. While poor binding properties were observed by NMR for the newly synthesized C6U, receptors C3U and C3TU exhibited a unique ability to cooperatively complex a dicarboxylate anion sandwiched between two ammonium ions. The three ions are complexed in contact and aligned within the tubular shape of the receptor, forming cascade complexes that are stable even in a competitive environment. The different binding properties between the receptors were rationalized in terms of size, flexibility, H-bond donor ability, and intramolecular H-bonding within the anion binding pocket between the calixarene cavities. With C3U, a rare selectivity for oxalate over other small dicarboxylates and various bicharged anions was observed. Molecular modeling of the cascade complex indicated that the oxalate anion is stabilized by an array of hydrogen bonds with the urea bridges of the receptor and both propylammonium cations nested within the calixarene cavities.
    Language English
    Publishing date 2023-08-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d3ob00947e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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