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Article ; Online: Structure of PD1 and its mechanism in the treatment of autoimmune diseases.

Rezayi, Mahdi / Hosseini, Arezoo

2023 Volume 41, Issue 7, Page(s) 726–737

Abstract: PD-1 and CTLA-4 can play an important role in addressing the issue of autoimmune diseases. PD-1 is a transmembrane glycoprotein expressed on T, B, and Dentric cells. This molecule functions as a checkpoint in T cell proliferation. Ligation of PD-1 with ... ...

Abstract	PD-1 and CTLA-4 can play an important role in addressing the issue of autoimmune diseases. PD-1 is a transmembrane glycoprotein expressed on T, B, and Dentric cells. This molecule functions as a checkpoint in T cell proliferation. Ligation of PD-1 with its ligands inhibits the production of IL-2, IL-7, IL-10, and IL-12 as well as other cytokines by macrophages, natural killer (NK) cells, and T cells, which can suppress cell proliferation and inflammation. Today, scientists attempt to protect against autoimmune diseases by PD-1 inhibitory signals. In this review, we discuss the structure, expression, and signaling pathway of PD-1. In addition, we discuss the importance of PD-1 in regulating several autoimmune diseases, reflecting how manipulating this molecule can be an effective method in the immunotherapy of some autoimmune diseases.
MeSH term(s)	Humans ; Autoimmune Diseases/therapy ; Cytokines/metabolism ; Inflammation ; Programmed Cell Death 1 Receptor/metabolism
Chemical Substances	Cytokines ; Programmed Cell Death 1 Receptor ; PDCD1 protein, human
Language	English
Publishing date	2023-07-20
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	283643-9
ISSN	1099-0844 ; 0263-6484
ISSN (online)	1099-0844
ISSN	0263-6484
DOI	10.1002/cbf.3827
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Article ; Online: Evaluation of Three Methods for the Treatment of Dentin Hypersensitivity: A Randomised Clinical Trial.

Naghsh, Narges / Hosseini, Arezoo / Bazmara, Azin / Birang, Reza

International dental journal

2024

Abstract: Objectives: In this study, we aimed to compare the effectiveness of Gluma and high-power 980-nm diode laser, alone or in combination, in the treatment of cervical dentin hypersensitivity.: Methods: A total of 20 patients (5 men and 15 women), aged 25 ...

Abstract	Objectives: In this study, we aimed to compare the effectiveness of Gluma and high-power 980-nm diode laser, alone or in combination, in the treatment of cervical dentin hypersensitivity. Methods: A total of 20 patients (5 men and 15 women), aged 25 to 60 years, who met the inclusion criteria, were enrolled in this study. A total of 60 teeth were randomly divided into 4 groups: G1, 980 nm diode laser (in 2 sessions within a 1-week interval); G2, Gluma (in 2 sessions within a 1-week interval); G3, 980 nm diode laser plus Gluma; and G4: control. Thermal (cold spray) and air blast (air syringe of dental unit) stimuli were used to evaluate cervical dentin hypersensitivity in the patients. Their pain response was assessed using a visual analogue scale (VAS) before treatment (baseline), in the first treatment session (15 minutes after treatment), in the second treatment session (after 1 week), and in 2-week, 1-month, and 3-month follow-up sessions. The obtained data were analysed using non-parametric tests, including Kruskal-Wallis test, Friedman test, Mann-Whitney test, and Wilcoxon test, in SPSS Version 22 at a significance level of P < .05. Results: Based on the results, there was a significant difference in the average VAS scores for cold and air blast stimuli between the 4 groups 1 month after the intervention (P < .05). Meanwhile, the laser group had the lowest VAS score for cold and air stimuli. On the contrary, no significant difference was found between the 4 groups 3 months after the intervention (P ˃ .05). Conclusion: The present results showed that 980-nm diode laser alone was more effective than the other 2 intervention methods for 1 month. Trial registration: The study was registered in the Iranian Registry of Clinical Trials (IRCT20120901010703N5).
Language	English
Publishing date	2024-04-12
Publishing country	England
Document type	Journal Article
ZDB-ID	218262-2
ISSN	1875-595X ; 0020-6539
ISSN (online)	1875-595X
ISSN	0020-6539
DOI	10.1016/j.identj.2024.03.013
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Article ; Online: Effects of Propolis-Based Herbal Toothpaste on Dentine Hypersensitivity.

Naghsh, Narges / Mazrooei, Fatemeh / Hosseini, Arezoo / Kiani, Sima / Sahebkar, Amirhossein

International dental journal

2024

Abstract: Introduction: The objective of this in vitro study was to compare the effectiveness of a propolis-based herbal toothpaste with 5% sodium fluoride varnishin obstructing human dentinal tubules; Scanning electron microscopy was utilised to obtain ... ...

Abstract	Introduction: The objective of this in vitro study was to compare the effectiveness of a propolis-based herbal toothpaste with 5% sodium fluoride varnishin obstructing human dentinal tubules; Scanning electron microscopy was utilised to obtain quantitative and qulitative data on tubular obstruction. Methods: Thirty-nine extracted human premolar teeth were collected. The cementum layer was removed using a water-cooled diamond bur and the smear layer using ethylenediaminetetraacetic acid (EDTA) 17%. Then, the samples were randomly divided into 3 groups (n = 13 each), as follows: group 1: dentin discs exposed to the propolis-based herbal toothpaste (Herbex); group 2: dentin discs exposed to 5% sodium fluoride varnish; and group 3: control. Then, all discs were observed and imaged in 4 non-overlapping fields by an electron microscope at 2000× magnification. The topography and number of open, closed, and semi-closed tubules were counted in all images. The data were analysed using Kruskal-Wallis test, Mann-Whitney U test, and Friedman test. The statistical analysis was performed with SPSS statistic 22.0 software, with a significance level of α = 0.05. Results: In pairwise comparisons of the groups considering the percentage of open, closed, and semi-closed tubules, the difference was not statistically significant between the 5% sodium fluoride varnish and propolis groups in the closed and semi-closed tubules, but it was statistically significant with the control group. Additionally, the percentage of open tubules in the propolis-based herbal toothpaste group was significantly lower than in the 5% sodium fluoride varnish and control group. Conclusions: Both propolis-based herbal toothpaste and 5% sodium fluoride varnish is effective in blocking human dentin tubules to various extents.
Language	English
Publishing date	2024-01-05
Publishing country	England
Document type	Journal Article
ZDB-ID	218262-2
ISSN	1875-595X ; 0020-6539
ISSN (online)	1875-595X
ISSN	0020-6539
DOI	10.1016/j.identj.2023.11.014
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Article: Corrigendum: Cardioprotective effect of

Hosseini, Azar / Ghorbani, Atieh / Sadat Alavi, Mohaddeseh / Forouhi, Nima / Rajabian, Arezoo / Boroumand-Noughabi, Samaneh / Sahebkar, Amirhossein / Eid, Ali H

Frontiers in pharmacology

2024 Volume 15, Page(s) 1374595

Abstract: This corrects the article DOI: 10.3389/fphar.2023.1305816.]. ...

Abstract	[This corrects the article DOI: 10.3389/fphar.2023.1305816.].
Language	English
Publishing date	2024-02-21
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2024.1374595
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Article ; Online: Theoretical definition of nurse-conscious mechanically ventilated patient communication: a scoping review with qualitative content analysis.

Ghiasvand, Arezoo Mohamadkhani / Hosseini, Meimanat / Atashzadeh-Shoorideh, Foroozan

Acute and critical care

2023 Volume 38, Issue 1, Page(s) 8–20

Abstract: Providing critical nursing care for conscious mechanically ventilated patients is mediated via effective communication. This study aimed to identify and map the antecedents, attributes, consequences, and definition of nurse-conscious mechanically ... ...

Abstract	Providing critical nursing care for conscious mechanically ventilated patients is mediated via effective communication. This study aimed to identify and map the antecedents, attributes, consequences, and definition of nurse-conscious mechanically ventilated patient communication (N-CMVPC). This scoping review was conducted by searching the Cochrane Library and the CINAHL, EMBASE, PubMed, Web of Science, and Scopus databases, between 2001 and 2021. The keywords queried included "nurses," "mechanically ventilated patients," "mechanical ventilation," "intubated patients," "communication," "interaction," "relationships," "nurse-patient communication," "nurse-patient relations," "intensive care units," and "critical care." Studies related to communication with healthcare personnel or family members were excluded. The results indicated that N-CMVPC manifests as a set of attributes in communication experiences, emotions, methods, and behaviors of the nurse and the patient and is classified into three main themes, nurse communication, patient communication, and quantitative-qualitative aspects. N-CMVPC is a complex, multidimensional, and multi-factor concept. It is often nurse-controlled and can express itself as questions, sentences, or commands in the context of experiences, feelings, and positive or negative behaviors involving the nurse and the patient.
Language	English
Publishing date	2023-02-27
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	3003021-3
ISSN	2586-6060 ; 2586-6052
ISSN (online)	2586-6060
ISSN	2586-6052
DOI	10.4266/acc.2022.01039
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Article: The effect of laparoscopic ovarian drilling on pregnancy outcomes in polycystic ovary syndrome women with more than 2 in-vitro fertilization cycle failures: A pilot RCT.

Moini, Ashraf / Esfidani, Tayebeh / Arabipoor, Arezoo / Hosseini, Reihaneh / Mohiti, Shima / Noor Mohammadi, Sakineh

International journal of reproductive biomedicine

2023 Volume 21, Issue 11, Page(s) 901–908

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2023-12-19
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2898387-7
ISSN	2476-3772 ; 2476-4108
ISSN (online)	2476-3772
ISSN	2476-4108
DOI	10.18502/ijrm.v21i11.14653
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Article: Effect of nifedipine with and without sildenafil citrate for the management of preterm labor in pregnant women: A randomized clinical trial.

Nasrolahei, Shahla / Arezoo Hoseini, Seyedeh / Azadeh Hosseini, Seyedeh / Narjes Khatoon Hosseini, Seyedeh / Sahar Hosseini, Seyedeh / Moradian Lotfi, Parsa

International journal of reproductive biomedicine

2023 Volume 21, Issue 5, Page(s) 379–386

Abstract: Background: Preterm labor is one of the main causes of neonatal mortality and its treatment is still challenging.: Objective: The study aimed to compare the effectiveness of nifedipine (Nif) with and without sildenafil citrate (SC) for the treatment ... ...

Abstract	Background: Preterm labor is one of the main causes of neonatal mortality and its treatment is still challenging. Objective: The study aimed to compare the effectiveness of nifedipine (Nif) with and without sildenafil citrate (SC) for the treatment of preterm labor in pregnant women. Materials and methods: In this clinical trial study, 126 pregnant women referred to the Fatemieh hospital, Hamadan, Iran with a complaint of preterm labor were evaluated. Participants were randomly divided into 2 groups of Nif 20 mg orally (single dose), then 10 mg every 6-hr, and at the same time vaginal SC 25 mg every 8 hr (Nif + SC) or Nif alone. Treatment was continued for 48-72 hr if uterine contractions did not resolve in both groups. Delivery rates at the time of hospitalization and neonatal outcome were compared between the 2 groups. Results: No statistically significant difference was observed between the 2 study groups in terms of mean age, gestational age, body mass index, and parity. 76.2% of Nif + SC participants in the first 72 hr of hospitalization and 57.2% of Nif participants remained without delivery (p = 0.02). The neonatal hospitalization rate of the Nif + SC group in the neonatal intensive care unit was 25.4% and in the Nif group was 42.9% (p = 0.03). Conclusion: Nif with SC is superior to Nif alone in women at risk of preterm labor due to increasing gestational age and better neonatal outcomes.
Language	English
Publishing date	2023-05-12
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2898387-7
ISSN	2476-3772 ; 2476-4108
ISSN (online)	2476-3772
ISSN	2476-4108
DOI	10.18502/ijrm.v21i5.13471
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Article ; Online: The Effects of Curcumin Plus Piperine Co-administration on Inflammation and Oxidative Stress: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Hosseini, Hossein / Ghavidel, Farideh / Rajabian, Arezoo / Homayouni-Tabrizi, Masoud / Majeed, Muhammed / Sahebkar, Amirhossein

Current medicinal chemistry

2024

Abstract: Background: The beneficial effects of curcumin against various chronic disorders have been shown in the last few decades. However, due to its low bioavailability, therapeutic effects are less than expected. Piperine has been used in scientific ... ...

Abstract	Background: The beneficial effects of curcumin against various chronic disorders have been shown in the last few decades. However, due to its low bioavailability, therapeutic effects are less than expected. Piperine has been used in scientific evaluations as an effective compound to increase the bioavailability of curcumin. The present review investigated the impact of curcumin plus piperine intake on oxidative stress and inflammatory markers of Randomized Clinical Trials (RCTs). Methods: Using relevant keywords, we searched Cochrane Library, Scopus, PubMed, and Web of Science between January 1st, 1970, and September 30th, 2022. A comprehensive search for RCTs was performed. Continuous data were pooled by Standard Mean Difference (SMD) and 95% confidence interval. All related statistical analyses were performed using Comprehensive Meta-Analysis (CMA) software. Results: A total of 13 articles were incorporated into the final meta-analysis. According to the current meta-analysis, curcumin plus piperine administration showed a significantly increased SOD activity and GSH levels while significantly decreased MDA concentrations. In addition, our study revealed that curcumin plus piperine significantly decreased TNF-α and IL-6 concentrations. Conclusion: These results indicated that curcumin plus piperine administration could effectively reduce oxidative stress and inflammation.
Language	English
Publishing date	2024-03-29
Publishing country	United Arab Emirates
Document type	Meta-Analysis
ZDB-ID	1319315-6
ISSN	1875-533X ; 0929-8673
ISSN (online)	1875-533X
ISSN	0929-8673
DOI	10.2174/0109298673260515240322074849
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Article: Cardioprotective effect of

Hosseini, Azar / Ghorbani, Atieh / Alavi, Mohaddeseh Sadat / Forouhi, Nima / Rajabian, Arezoo / Boroumand-Noughabi, Samaneh / Sahebkar, Amirhossein / Eid, Ali H

Frontiers in pharmacology

2023 Volume 14, Page(s) 1305816

Abstract: Introduction: ...

Abstract	Introduction:
Language	English
Publishing date	2023-12-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2587355-6
ISSN	1663-9812
ISSN	1663-9812
DOI	10.3389/fphar.2023.1305816
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Article ; Online: Tele-Urology in the Era of COVID-19: an Experience of the Reconstructive Urology Department in Iran.

Hosseini, Jalil / Eslami, Amir Hossein / Nematollahi, Shahrzad / Sharifian, Rayka / Sheikh Milani, Arezoo / Fatemi, Alireza

Urology journal

2024

Abstract: Introduction: The outbreak of coronavirus has put additional pressure on the health care systems of many countries; but telemedicine can be an important way to deal with it, especially for people whose health has been affected by the virus. The present ... ...

Abstract	Introduction: The outbreak of coronavirus has put additional pressure on the health care systems of many countries; but telemedicine can be an important way to deal with it, especially for people whose health has been affected by the virus. The present study aims to investigate the Implementation of a Tele-urology Program for Reconstructive Urologic Referrals: Initial Results and Patient Satisfaction. Material and methods: All patients with a history of a urethral reconstructive surgery during last year was entered to our study and two nurses collected data of demographic and past medical history of patients by existed. Telephone visits:Fellowship of reconstructive urology was connected to patients during a phone call and filled the USS-PROM and COVID-19 questionnaires. Face to face visits: All patients were asked to answer the questionnaire about recent exposure and infection by corona virus, recent travel and other risk factors of COVID-19. Results: Mean of USSPROM scale was calculated as 1.65 (+2.91) with a range of 0-15. Based on categorization for USSPROM scale, 74 patients (94.8%) had mild symptoms while 4 patients (5.1%) had moderate symptoms and needed further medical attention. Four patients with moderate USSPROM score were required to cystoscopic evaluation, which one patient with moderate USSPROM score had severe stricture and candidate for redo urethroplasty. Two other patients need for urethral stricture dilatation. Cost was calculated based on taxi-service fee. Accordingly, the average (+SD) cost for in-person visits to the physician was estimated as 4.80 + 4.32 million Rials. In terms of distance, the average distance for receiving medical services according to the patient`s residence area was 373.2 +348.79 kilometres.In terms of the patient`s opinion regarding virtual examination, inappropriateness of virtual visits for physical examination, and patient`s inability to explain the problem correctly, patient`s condition at the time of the virtual visit were the main challenges reported by the respondent. Conclusion: Considering that the present COVID-19 emergency will likely last for months, telehealth could be the safest way to deliver urological care for a large percentage of the patients, such as those who are more at risk of unfavorable outcomes of COVID-19.
Language	English
Publishing date	2024-03-17
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2251940-3
ISSN	1735-546X ; 1735-1308
ISSN (online)	1735-546X
ISSN	1735-1308
DOI	10.22037/uj.v20i.8096
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