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  1. Article ; Online: Hydrolytic degradation and biodegradation of polylactic acid electrospun fibers.

    Soo, Xiang Yun Debbie / Jia, Linran / Lim, Qi Feng / Chua, Ming Hui / Wang, Suxi / Hui, Hui Kim / See, Jia Min Regine / Chen, Yunjie / Li, Jiuwei / Wei, Fengxia / Tomczak, Nikodem / Kong, Junhua / Loh, Xian Jun / Fei, Xunchang / Zhu, Qiang

    Chemosphere

    2024  Volume 350, Page(s) 141186

    Abstract: Increased use of bioplastics, such as polylactic acid (PLA), helps in reducing greenhouse gas emissions, decreases energy consumption and lowers pollution, but its degradation efficiency has much room for improvement. The degradation rate of electrospun ... ...

    Abstract Increased use of bioplastics, such as polylactic acid (PLA), helps in reducing greenhouse gas emissions, decreases energy consumption and lowers pollution, but its degradation efficiency has much room for improvement. The degradation rate of electrospun PLA fibers of varying diameters ranging from 0.15 to 1.33 μm is measured during hydrolytic degradation under different pH from 5.5 to 10, and during aerobic biodegradation in seawater supplemented with activated sewage sludge. In hydrolytic conditions, varying PLA fiber diameter had significant influence over percentage weight loss (W
    MeSH term(s) Polyesters/chemistry ; Hydrolysis ; Microscopy, Electron, Scanning
    Chemical Substances poly(lactide) (459TN2L5F5) ; Polyesters
    Language English
    Publishing date 2024-01-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2024.141186
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  2. Article: Innovative Face Shields Help Frontliners Face-off COVID-19 Pandemic.

    Chua, Jia Xiang / Ong, Lynette / Tan, Cher Heng

    Annals of the Academy of Medicine, Singapore

    2020  Volume 49, Issue 12, Page(s) 1044–1047

    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/transmission ; Equipment Design ; Health Personnel ; Humans ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Inventions ; Occupational Diseases/prevention & control ; Pandemics ; Personal Protective Equipment ; Singapore/epidemiology
    Language English
    Publishing date 2020-09-28
    Publishing country Singapore
    Document type Letter
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    DOI 10.47102/annals-acadmedsg.2020309
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  3. Article ; Online: Singapore radiographers' perceptions and expectations of artificial intelligence - A qualitative study.

    Ng, Chloe Theresia / Roslan, Sri Nur Aidah / Chng, Yi Hong / Choong, Denise Ai Wen / Chong, Ai Jia Letty / Tay, Yi Xiang / Lança, Luis / Chua, Eric Chern-Pin

    Journal of medical imaging and radiation sciences

    2022  Volume 53, Issue 4, Page(s) 554–563

    Abstract: Introduction: With the emergence of artificial intelligence (AI) in medical imaging, radiographers are likely to be at the forefront of this technological advancement. Studies have therefore been conducted recently to understand radiographers' opinions ... ...

    Abstract Introduction: With the emergence of artificial intelligence (AI) in medical imaging, radiographers are likely to be at the forefront of this technological advancement. Studies have therefore been conducted recently to understand radiographers' opinions on AI adoption. This study extends that work by using a qualitative approach to further explore radiographers' knowledge, perceptions, and expectations of AI.
    Method: Six online focus groups were conducted with 22 radiographers from the three public healthcare clusters in Singapore. They were purposively sampled, and participants were recruited from a broad demographic background with varying years of working experience and designations. The focus group sessions were transcribed verbatim and thematic analysis was performed on their responses.
    Results: Participants demonstrated limited knowledge of AI. Their perceptions of AI were mixed, recognising its benefits in increasing efficiency and improving patient care, but also aware of its limitations in accuracy and bias. On how patients may perceive AI, participants felt that patients would accept AI if they felt it improves their care but may reject it once they lose trust in it. Expectations wise, participants envisioned several applications in pre-, peri‑, and post-procedural workflows including order vetting, patient positioning, language translation, and artefact removal. On radiographers' role and career opportunities, some participants see an opportunity for radiographers to specialise in AI, becoming involved in algorithm development and its clinical implementation.
    Discussion: Our findings suggest that widespread implementation of AI would require limited knowledge amongst radiographers and current AI limitations to be addressed. While radiographers are positively anticipating the integration of AI into their practices, they should also become actively involved in the development of AI tools such that those they envisioned. This would help align optimal use of AI tools and radiographer role changes. Patients' acceptance and reactions to AI also warrant further research.
    MeSH term(s) Humans ; Artificial Intelligence ; Motivation ; Singapore ; Allied Health Personnel ; Radiography
    Language English
    Publishing date 2022-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2426513-5
    ISSN 1876-7982 ; 1939-8654
    ISSN (online) 1876-7982
    ISSN 1939-8654
    DOI 10.1016/j.jmir.2022.08.005
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  4. Article ; Online: Ethanol extract of mulberry leaves partially restores the composition of intestinal microbiota and strengthens liver glycogen fragility in type 2 diabetic rats.

    Liu, Zhan-Zhong / Liu, Qing-Hua / Liu, Zhao / Tang, Jia-Wei / Chua, Eng-Guan / Li, Fen / Xiong, Xue-Song / Wang, Meng-Meng / Wen, Peng-Bo / Shi, Xin-Yi / Xi, Xiang-Yu / Zhang, Xiao / Wang, Liang

    BMC complementary medicine and therapies

    2021  Volume 21, Issue 1, Page(s) 172

    Abstract: Background: Mulberry leaf as a traditional Chinese medicine is able to treat obesity, diabetes, and dyslipidemia. It is well known that diabetes leads to intestinal microbiota dysbiosis. It is also recently discovered that liver glycogen structure is ... ...

    Abstract Background: Mulberry leaf as a traditional Chinese medicine is able to treat obesity, diabetes, and dyslipidemia. It is well known that diabetes leads to intestinal microbiota dysbiosis. It is also recently discovered that liver glycogen structure is impaired in diabetic animals. Since mulberry leaves are able to improve the diabetic conditions through reducing blood glucose level, it would be interesting to investigate whether they have any positive effects on intestinal microbiota and liver glycogen structure.
    Methods: In this study, we first determined the bioactive components of ethanol extract of mulberry leaves via high-performance liquid chromatography (HPLC) and liquid chromatography/mass spectrometry (LC/MS). Murine animal models were divided into three groups, normal Sprague-Dawley (SD) rats, high-fat diet (HFD) and streptozotocin (STZ) induced type 2 diabetic rats, and HFD/STZ-induced rats administered with ethanol extract of mulberry leaves (200 mg/kg/day). Composition of intestinal microbiota was analyzed via metagenomics by sequencing the V3-V4 region of 16S rDNAs. Liver glycogen structure was characterized through size exclusion chromatography (SEC). Both Student's t-test and Tukey's test were used for statistical analysis.
    Results: A group of type 2 diabetic rat models were successfully established. Intestinal microbiota analysis showed that ethanol extract of mulberry leaves could partially change intestinal microbiota back to normal conditions. In addition, liver glycogen was restored from fragile state to stable state through administration of ethanol extract of mulberry leaves.
    Conclusions: This study confirms that the ethanol extract of mulberry leaves (MLE) ameliorates intestinal microbiota dysbiosis and strengthens liver glycogen fragility in diabetic rats. These finding can be helpful in discovering the novel therapeutic targets with the help of further investigations.
    MeSH term(s) Animals ; Diabetes Mellitus, Experimental/drug therapy ; Diabetes Mellitus, Type 2/drug therapy ; Dysbiosis/prevention & control ; Ethanol/chemistry ; Gastrointestinal Microbiome/drug effects ; Liver Glycogen/analysis ; Morus/chemistry ; Plant Extracts/pharmacology ; Plant Leaves/chemistry ; Rats, Sprague-Dawley ; Rats
    Chemical Substances Liver Glycogen ; Plant Extracts ; Ethanol (3K9958V90M)
    Language English
    Publishing date 2021-06-14
    Publishing country England
    Document type Journal Article
    ISSN 2662-7671
    ISSN (online) 2662-7671
    DOI 10.1186/s12906-021-03342-x
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  5. Article: Ethanol extract of mulberry leaves partially restores the composition of intestinal microbiota and strengthens liver glycogen fragility in type 2 diabetic rats

    Liu, Zhan-Zhong / Liu, Qing-Hua / Liu, Zhao / Tang, Jia-Wei / Chua, Eng-Guan / Li, Fen / Xiong, Xue-Song / Wang, Meng-Meng / Wen, Peng-Bo / Shi, Xin-Yi / Xi, Xiang-Yu / Zhang, Xiao / Wang, Liang

    BMC complementary medicine and therapies. 2021 Dec., v. 21, no. 1

    2021  

    Abstract: BACKGROUND: Mulberry leaf as a traditional Chinese medicine is able to treat obesity, diabetes, and dyslipidemia. It is well known that diabetes leads to intestinal microbiota dysbiosis. It is also recently discovered that liver glycogen structure is ... ...

    Abstract BACKGROUND: Mulberry leaf as a traditional Chinese medicine is able to treat obesity, diabetes, and dyslipidemia. It is well known that diabetes leads to intestinal microbiota dysbiosis. It is also recently discovered that liver glycogen structure is impaired in diabetic animals. Since mulberry leaves are able to improve the diabetic conditions through reducing blood glucose level, it would be interesting to investigate whether they have any positive effects on intestinal microbiota and liver glycogen structure. METHODS: In this study, we first determined the bioactive components of ethanol extract of mulberry leaves via high-performance liquid chromatography (HPLC) and liquid chromatography/mass spectrometry (LC/MS). Murine animal models were divided into three groups, normal Sprague-Dawley (SD) rats, high-fat diet (HFD) and streptozotocin (STZ) induced type 2 diabetic rats, and HFD/STZ-induced rats administered with ethanol extract of mulberry leaves (200 mg/kg/day). Composition of intestinal microbiota was analyzed via metagenomics by sequencing the V3-V4 region of 16S rDNAs. Liver glycogen structure was characterized through size exclusion chromatography (SEC). Both Student’s t-test and Tukey’s test were used for statistical analysis. RESULTS: A group of type 2 diabetic rat models were successfully established. Intestinal microbiota analysis showed that ethanol extract of mulberry leaves could partially change intestinal microbiota back to normal conditions. In addition, liver glycogen was restored from fragile state to stable state through administration of ethanol extract of mulberry leaves. CONCLUSIONS: This study confirms that the ethanol extract of mulberry leaves (MLE) ameliorates intestinal microbiota dysbiosis and strengthens liver glycogen fragility in diabetic rats. These finding can be helpful in discovering the novel therapeutic targets with the help of further investigations.
    Keywords Oriental traditional medicine ; alternative medicine ; blood glucose ; dysbiosis ; ethanol ; gel chromatography ; glycogen ; high fat diet ; high performance liquid chromatography ; hyperlipidemia ; intestinal microorganisms ; leaves ; liver ; mass spectrometry ; metagenomics ; mice ; mulberries ; noninsulin-dependent diabetes mellitus ; obesity ; rats ; streptozotocin ; t-test
    Language English
    Dates of publication 2021-12
    Size p. 172.
    Publishing place BioMed Central
    Document type Article
    ISSN 2662-7671
    DOI 10.1186/s12906-021-03342-x
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Ethanol extract of mulberry leaves partially restores the composition of intestinal microbiota and strengthens liver glycogen fragility in type 2 diabetic rats

    Zhan-Zhong Liu / Qing-Hua Liu / Zhao Liu / Jia-Wei Tang / Eng-Guan Chua / Fen Li / Xue-Song Xiong / Meng-Meng Wang / Peng-Bo Wen / Xin-Yi Shi / Xiang-Yu Xi / Xiao Zhang / Liang Wang

    BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-

    2021  Volume 15

    Abstract: Abstract Background Mulberry leaf as a traditional Chinese medicine is able to treat obesity, diabetes, and dyslipidemia. It is well known that diabetes leads to intestinal microbiota dysbiosis. It is also recently discovered that liver glycogen ... ...

    Abstract Abstract Background Mulberry leaf as a traditional Chinese medicine is able to treat obesity, diabetes, and dyslipidemia. It is well known that diabetes leads to intestinal microbiota dysbiosis. It is also recently discovered that liver glycogen structure is impaired in diabetic animals. Since mulberry leaves are able to improve the diabetic conditions through reducing blood glucose level, it would be interesting to investigate whether they have any positive effects on intestinal microbiota and liver glycogen structure. Methods In this study, we first determined the bioactive components of ethanol extract of mulberry leaves via high-performance liquid chromatography (HPLC) and liquid chromatography/mass spectrometry (LC/MS). Murine animal models were divided into three groups, normal Sprague-Dawley (SD) rats, high-fat diet (HFD) and streptozotocin (STZ) induced type 2 diabetic rats, and HFD/STZ-induced rats administered with ethanol extract of mulberry leaves (200 mg/kg/day). Composition of intestinal microbiota was analyzed via metagenomics by sequencing the V3-V4 region of 16S rDNAs. Liver glycogen structure was characterized through size exclusion chromatography (SEC). Both Student’s t-test and Tukey’s test were used for statistical analysis. Results A group of type 2 diabetic rat models were successfully established. Intestinal microbiota analysis showed that ethanol extract of mulberry leaves could partially change intestinal microbiota back to normal conditions. In addition, liver glycogen was restored from fragile state to stable state through administration of ethanol extract of mulberry leaves. Conclusions This study confirms that the ethanol extract of mulberry leaves (MLE) ameliorates intestinal microbiota dysbiosis and strengthens liver glycogen fragility in diabetic rats. These finding can be helpful in discovering the novel therapeutic targets with the help of further investigations.
    Keywords Type 2 diabetes mellitus ; Ethanol extract of mulberry leaves ; Intestinal microbiota ; 16 s rDNA ; HFD/STZ treatment ; Other systems of medicine ; RZ201-999
    Subject code 610
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Comprehensive molecular phenotyping of

    Xu, Chang / Huang, Kie Kyon / Law, Jia Hao / Chua, Joy Shijia / Sheng, Taotao / Flores, Natasha M / Pizzi, Melissa Pool / Okabe, Atsushi / Tan, Angie Lay Keng / Zhu, Feng / Kumar, Vikrant / Lu, Xiaoyin / Benitez, Ana Morales / Lian, Benedict Shi Xiang / Ma, Haoran / Ho, Shamaine Wei Ting / Ramnarayanan, Kalpana / Anene-Nzelu, Chukwuemeka George / Razavi-Mohseni, Milad /
    Abdul Ghani, Siti Aishah Binte / Tay, Su Ting / Ong, Xuewen / Lee, Ming Hui / Guo, Yu Amanda / Ashktorab, Hassan / Smoot, Duane / Li, Shang / Skanderup, Anders Jacobsen / Beer, Michael A / Foo, Roger Sik Yin / Wong, Joel Shi Hao / Sanghvi, Kaushal / Yong, Wei Peng / Sundar, Raghav / Kaneda, Atsushi / Prabhakar, Shyam / Mazur, Pawel Karol / Ajani, Jaffer A / Yeoh, Khay Guan / So, Jimmy Bok-Yan / Tan, Patrick

    Gut

    2023  Volume 72, Issue 9, Page(s) 1651–1663

    Abstract: Objective: Gastric cancer (GC) is a leading cause of cancer mortality, with : Design: Genomic profiling of GC patients including a Singapore cohort (>200 patients) was performed to derive mutational signatures of : Results: We observed prevalent !# ...

    Abstract Objective: Gastric cancer (GC) is a leading cause of cancer mortality, with
    Design: Genomic profiling of GC patients including a Singapore cohort (>200 patients) was performed to derive mutational signatures of
    Results: We observed prevalent
    Conclusion: Our results suggest a therapeutic strategy for
    MeSH term(s) Humans ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Stomach Neoplasms/genetics ; Stomach Neoplasms/therapy ; Stomach Neoplasms/pathology ; Nuclear Proteins/genetics ; Epigenomics ; Mutation ; Tumor Microenvironment/genetics ; DNA-Binding Proteins/genetics ; Cell Cycle Proteins/genetics
    Chemical Substances Transcription Factors ; Nuclear Proteins ; ARID1A protein, human ; DNA-Binding Proteins ; BRD4 protein, human ; Cell Cycle Proteins
    Language English
    Publishing date 2023-03-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80128-8
    ISSN 1468-3288 ; 0017-5749
    ISSN (online) 1468-3288
    ISSN 0017-5749
    DOI 10.1136/gutjnl-2022-328332
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  8. Article ; Online: Containment of COVID-19 cases among healthcare workers: The role of surveillance, early detection, and outbreak management.

    Wee, Liang En / Sim, Xiang Ying Jean / Conceicao, Edwin Philip / Aung, May Kyawt / Goh, Jia Qing / Yeo, Dennis Wu Ting / Gan, Wee Hoe / Chua, Ying Ying / Wijaya, Limin / Tan, Thuan Tong / Tan, Ban Hock / Ling, Moi Lin / Venkatachalam, Indumathi

    Infection control and hospital epidemiology

    2020  Volume 41, Issue 7, Page(s) 765–771

    Abstract: Objective: Staff surveillance is crucial during the containment phase of a pandemic to help reduce potential healthcare-associated transmission and sustain good staff morale. During an outbreak of SARS-COV-2 with community transmission, our institution ... ...

    Abstract Objective: Staff surveillance is crucial during the containment phase of a pandemic to help reduce potential healthcare-associated transmission and sustain good staff morale. During an outbreak of SARS-COV-2 with community transmission, our institution used an integrated strategy for early detection and containment of COVID-19 cases among healthcare workers (HCWs).
    Methods: Our strategy comprised 3 key components: (1) enforcing reporting of HCWs with acute respiratory illness (ARI) to our institution's staff clinic for monitoring; (2) conducting ongoing syndromic surveillance to obtain early warning of potential clusters of COVID-19; and (3) outbreak investigation and management.
    Results: Over a 16-week surveillance period, we detected 14 cases of COVID-19 among HCWs with ARI symptoms. Two of the cases were linked epidemiologically and thus constituted a COVID-19 cluster with intrahospital HCW-HCW transmission; we also detected 1 family cluster and 2 clusters among HCWs who shared accommodation. No transmission to HCWs or patients was detected after containment measures were instituted. Early detection minimized the number of HCWs requiring quarantine, hence preserving continuity of service during an ongoing pandemic.
    Conclusions: An integrated surveillance strategy, outbreak management, and encouraging individual responsibility were successful in early detection of clusters of COVID-19 among HCWs. With ongoing local transmission, vigilance must be maintained for intrahospital spread in nonclinical areas where social mingling of HCWs occurs. Because most individuals with COVID-19 have mild symptoms, addressing presenteeism is crucial to minimize potential staff and patient exposure.
    MeSH term(s) Adult ; COVID-19 ; Cluster Analysis ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Early Diagnosis ; Female ; Hospitals, General ; Humans ; Infection Control/methods ; Male ; Middle Aged ; Pandemics/prevention & control ; Personnel, Hospital ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Population Surveillance ; Singapore/epidemiology ; Symptom Assessment ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-05-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2020.219
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  9. Article: Containment of COVID-19 cases among healthcare workers: The role of surveillance, early detection, and outbreak management

    Wee, Liang En / Sim, Xiang Ying Jean / Conceicao, Edwin Philip / Aung, May Kyawt / Goh, Jia Qing / Yeo, Dennis Wu Ting / Gan, Wee Hoe / Chua, Ying Ying / Wijaya, Limin / Tan, Thuan Tong / Tan, Ban Hock / Ling, Moi Lin / Venkatachalam, Indumathi

    Infect Control Hosp Epidemiol

    Abstract: OBJECTIVE: Staff surveillance is crucial during the containment phase of a pandemic to help reduce potential healthcare-associated transmission and sustain good staff morale. During an outbreak of SARS-COV-2 with community transmission, our institution ... ...

    Abstract OBJECTIVE: Staff surveillance is crucial during the containment phase of a pandemic to help reduce potential healthcare-associated transmission and sustain good staff morale. During an outbreak of SARS-COV-2 with community transmission, our institution used an integrated strategy for early detection and containment of COVID-19 cases among healthcare workers (HCWs). METHODS: Our strategy comprised 3 key components: (1) enforcing reporting of HCWs with acute respiratory illness (ARI) to our institution's staff clinic for monitoring; (2) conducting ongoing syndromic surveillance to obtain early warning of potential clusters of COVID-19; and (3) outbreak investigation and management. RESULTS: Over a 16-week surveillance period, we detected 14 cases of COVID-19 among HCWs with ARI symptoms. Two of the cases were linked epidemiologically and thus constituted a COVID-19 cluster with intrahospital HCW-HCW transmission; we also detected 1 family cluster and 2 clusters among HCWs who shared accommodation. No transmission to HCWs or patients was detected after containment measures were instituted. Early detection minimized the number of HCWs requiring quarantine, hence preserving continuity of service during an ongoing pandemic. CONCLUSIONS: An integrated surveillance strategy, outbreak management, and encouraging individual responsibility were successful in early detection of clusters of COVID-19 among HCWs. With ongoing local transmission, vigilance must be maintained for intrahospital spread in nonclinical areas where social mingling of HCWs occurs. Because most individuals with COVID-19 have mild symptoms, addressing presenteeism is crucial to minimize potential staff and patient exposure.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #622776
    Database COVID19

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  10. Article ; Online: Containment of COVID-19 cases among healthcare workers

    Wee, Liang En / Sim, Xiang Ying Jean / Conceicao, Edwin Philip / Aung, May Kyawt / Goh, Jia Qing / Yeo, Dennis Wu Ting / Gan, Wee Hoe / Chua, Ying Ying / Wijaya, Limin / Tan, Thuan Tong / Tan, Ban Hock / Ling, Moi Lin / Venkatachalam, Indumathi

    Infection Control & Hospital Epidemiology

    The role of surveillance, early detection, and outbreak management

    2020  Volume 41, Issue 7, Page(s) 765–771

    Abstract: Abstract Objective: Staff surveillance is crucial during the containment phase of a pandemic to help reduce potential healthcare-associated transmission and sustain good staff morale. During an outbreak of SARS-COV-2 with community transmission, our ... ...

    Abstract Abstract Objective: Staff surveillance is crucial during the containment phase of a pandemic to help reduce potential healthcare-associated transmission and sustain good staff morale. During an outbreak of SARS-COV-2 with community transmission, our institution used an integrated strategy for early detection and containment of COVID-19 cases among healthcare workers (HCWs). Methods: Our strategy comprised 3 key components: (1) enforcing reporting of HCWs with acute respiratory illness (ARI) to our institution’s staff clinic for monitoring; (2) conducting ongoing syndromic surveillance to obtain early warning of potential clusters of COVID-19; and (3) outbreak investigation and management. Results: Over a 16-week surveillance period, we detected 14 cases of COVID-19 among HCWs with ARI symptoms. Two of the cases were linked epidemiologically and thus constituted a COVID-19 cluster with intrahospital HCW–HCW transmission; we also detected 1 family cluster and 2 clusters among HCWs who shared accommodation. No transmission to HCWs or patients was detected after containment measures were instituted. Early detection minimized the number of HCWs requiring quarantine, hence preserving continuity of service during an ongoing pandemic. Conclusions: An integrated surveillance strategy, outbreak management, and encouraging individual responsibility were successful in early detection of clusters of COVID-19 among HCWs. With ongoing local transmission, vigilance must be maintained for intrahospital spread in nonclinical areas where social mingling of HCWs occurs. Because most individuals with COVID-19 have mild symptoms, addressing presenteeism is crucial to minimize potential staff and patient exposure.
    Keywords Microbiology (medical) ; Epidemiology ; Infectious Diseases ; covid19
    Language English
    Publisher Cambridge University Press (CUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2020.219
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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