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  1. Article ; Online: "Nationwide fever″ vs "Nationwide fear″ after optimizing the COVID-19 response in China.

    Chen, Hongguang / Zhang, Konglai

    Asian journal of psychiatry

    2023  Volume 82, Page(s) 103499

    MeSH term(s) Humans ; COVID-19 ; Fear ; SARS-CoV-2 ; China/epidemiology
    Language English
    Publishing date 2023-02-01
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2023.103499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: [No title information]

    Wang, Lifang / Chen, Wenhu / Li, Xiaoyan / Zhao, Hongguang

    Current cancer drug targets

    2022  

    Language English
    Publishing date 2022-04-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2064824-8
    ISSN 1873-5576 ; 1568-0096
    ISSN (online) 1873-5576
    ISSN 1568-0096
    DOI 10.2174/1568009622666220407102725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Observation of the Effects of Different Enzyme Digestion Time and Enzyme Digestion Methods on the Extraction of Primary Renal Tubular Epithelial Cells from Sprague-Dawley Suckling Mice.

    Sun, Tian / Chen, Hongguang / Zhang, Zhenwang

    Biochemical genetics

    2024  

    Abstract: Renal tubular epithelial cells are one of the essential functional cells in the kidney. Optimizing the isolation and culture method of primary renal tubular epithelial cells from SD mammary rats provides better experimental materials for renal tubule- ... ...

    Abstract Renal tubular epithelial cells are one of the essential functional cells in the kidney. Optimizing the isolation and culture method of primary renal tubular epithelial cells from SD mammary rats provides better experimental materials for renal tubule-related studies, which is essential for studying the pathogenesis of renal diseases, especially diabetic nephropathy and drug screening. SD rat renal tubular epithelial cells were isolated and purified by 2.5-mg/ml collagenase II or 2 mg/ml trypsin + 2.5 mg/ml collagenase II enzymatic digestion. The isolation and purification were observed at different time points (15 min, 30 min, 45 min, and 60 min) to determine the optimal extraction time for the enzymatic digestion method. After comparing the two enzymatic methods, it was determined that the trypsin + collagenase II enzymatic method was more effective. The primary renal tubular epithelial cells extracted by the trypsin + collagenase II digestion method were identified by the marker Cytokeratin 18 of renal tubular epithelial cells at 45 min of digestion with high purity. We established a simple, efficient, and reproducible method for isolation and culture of renal tubular epithelial cells in SD mammary gland rats.
    Language English
    Publishing date 2024-03-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2168-4
    ISSN 1573-4927 ; 0006-2928
    ISSN (online) 1573-4927
    ISSN 0006-2928
    DOI 10.1007/s10528-024-10729-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A capillary-induced negative pressure is able to initiate heterogeneous cavitation.

    Chen, Shan / Zhang, Hongguang / Guo, Zhenjiang / Pagonabarraga, Ignacio / Zhang, Xianren

    Soft matter

    2024  Volume 20, Issue 12, Page(s) 2863–2870

    Abstract: A capillarity-induced negative pressure is of general importance for understanding the phase behaviors of liquids in small pores and cracks. A unique example is the embolism in the xylem of plants and the cavitation at the limiting negative pressure ... ...

    Abstract A capillarity-induced negative pressure is of general importance for understanding the phase behaviors of liquids in small pores and cracks. A unique example is the embolism in the xylem of plants and the cavitation at the limiting negative pressure generated by evaporation of water from nanocapillaries in the cell walls of leaves. In this work, by combining the effect of a capillary and cavitation together, we demonstrate with molecular dynamics (MD) simulations that capillarity is able to induce spontaneous cavitation in the presence of hydrophobic heterogeneities. Our simulation results reveal separately how the capillary generates a negative pressure and how the generated negative pressure affects the onset of cavitation. We then interpret the cavitation mechanism and determine the occurrence of cavitation as a function of the hydrophobicity of the nucleating substrates where the cavitation initiates and as a function of the hydrophilicity of the capillary tube from which the negative pressure generates. Our results reveal that the capillary-induced cavitation can be described well with a heterogeneous nucleation mechanism, within the framework of classical nucleation theory.
    Language English
    Publishing date 2024-03-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2191476-X
    ISSN 1744-6848 ; 1744-683X
    ISSN (online) 1744-6848
    ISSN 1744-683X
    DOI 10.1039/d4sm00143e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Dynamic Changes and Effects of H

    Zhang, Zhen / Wu, Xin / Kong, Yang / Zou, Peng / Wang, Yanbin / Zhang, Hongtao / Cui, Guangqiang / Zhu, Wei / Chen, Hongguang

    Biochemical genetics

    2024  

    Abstract: The aim of this study was to examine the expression changes of ... ...

    Abstract The aim of this study was to examine the expression changes of H
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2168-4
    ISSN 1573-4927 ; 0006-2928
    ISSN (online) 1573-4927
    ISSN 0006-2928
    DOI 10.1007/s10528-023-10557-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Self-assembly of fullerene C

    Li, Jinrui / Chen, Mengjun / Zhou, Shengju / Li, Hongguang / Hao, Jingcheng

    Chemical Society reviews

    2022  Volume 51, Issue 8, Page(s) 3226–3242

    Abstract: Fullerene ... ...

    Abstract Fullerene C
    Language English
    Publishing date 2022-04-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1472875-8
    ISSN 1460-4744 ; 0306-0012
    ISSN (online) 1460-4744
    ISSN 0306-0012
    DOI 10.1039/d1cs00958c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Thrombocytopenia in

    Chen, Lulu / Wang, Hongguang / Wang, Hairui / Guo, Yawen / Chang, Zhihui

    Frontiers in cellular and infection microbiology

    2024  Volume 14, Page(s) 1351607

    Abstract: Objective: Thrombocytopenia is commonly associated with infectious diseases and serves as an indicator of disease severity. However, reports on its manifestation in conjunction with : Materials and methods: A retrospective analysis of the clinical ... ...

    Abstract Objective: Thrombocytopenia is commonly associated with infectious diseases and serves as an indicator of disease severity. However, reports on its manifestation in conjunction with
    Materials and methods: A retrospective analysis of the clinical data from patients with KPLA admitted between June 2012 and June 2023 was performed. Baseline characteristics, biochemical assessments, therapeutic interventions, complications, and clinical outcomes were compared between patients with and without thrombocytopenia. To investigate the potential etiologies underlying thrombocytopenia, the association between platelet count reduction and thrombophlebitis was examined, with a particular focus on platelet consumption. Furthermore, bone marrow aspiration results were evaluated to assess platelet production anomalies.
    Results: A total of 361 KPLA patients were included in the study, among whom 60 (17%) had concurrent thrombocytopenia. Those in the thrombocytopenia group exhibited significantly higher rates of thrombophlebitis (p = 0.042), extrahepatic metastatic infection (p = 0.01), septic shock (p = 0.024), admissions to the intensive care unit (p = 0.002), and in-hospital mortality (p = 0.045). Multivariate analysis revealed that thrombocytopenia (odds ratio, 2.125; 95% confidence interval, 1.114-4.056; p = 0.022) was independently associated with thrombophlebitis. Among the thrombocytopenic patients, eight underwent bone marrow aspiration, and six (75%) had impaired medullar platelet production. After treatment, 88.6% of thrombocytopenic patients (n = 47) demonstrated recovery in their platelet counts with a median recovery time of five days (interquartile range, 3-6 days).
    Conclusions: Thrombocytopenia in patients with KPLA is indicative of increased disease severity. The underlying etiologies for thrombocytopenia may include impaired platelet production within the bone marrow and augmented peripheral platelet consumption as evidenced by the presence of thrombophlebitis.
    MeSH term(s) Humans ; Retrospective Studies ; Klebsiella pneumoniae ; Klebsiella Infections/complications ; Klebsiella Infections/epidemiology ; Liver Abscess/epidemiology ; Thrombocytopenia/complications ; Patient Acuity ; Thrombophlebitis/complications
    Language English
    Publishing date 2024-03-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2619676-1
    ISSN 2235-2988 ; 2235-2988
    ISSN (online) 2235-2988
    ISSN 2235-2988
    DOI 10.3389/fcimb.2024.1351607
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Synergism of Surfactant Mixture in Lowering Vapor-Liquid Interfacial Tension.

    Chen, Changsheng / Zhang, Hongguang / Zhang, Xianren

    Langmuir : the ACS journal of surfaces and colloids

    2023  Volume 39, Issue 33, Page(s) 11828–11838

    Abstract: Through employing molecular dynamics, in this work, we study how a two-component surfactant mixture cooperatively reduces the interfacial tension of a flat vapor-liquid interface. Our simulation results show that in the presence of a given insoluble ... ...

    Abstract Through employing molecular dynamics, in this work, we study how a two-component surfactant mixture cooperatively reduces the interfacial tension of a flat vapor-liquid interface. Our simulation results show that in the presence of a given insoluble surfactant, adding a secondary surfactant would either further reduce interfacial tension, indicating a positive synergistic effect, or increase the interfacial tension instead, indicating a negative synergistic effect. The synergism of the surfactant mixture in lowering surface tension is found to depend strongly on the structure complementary effect between different surfactant components. The synergistic mechanisms are then interpreted with minimization of the bending free energy of the composite surfactant monolayer via cooperatively changing the monolayer spontaneous curvature. By roughly describing the monolayer spontaneous curvature with the balanced distribution of surfactant heads and tails, we confirm that the positive synergistic effect in lowering surface tension is featured with the increasingly symmetric head-tail distributions, while the negative synergistic effect is featured with the increasingly asymmetric head-tail distributions. Furthermore, our simulation results indicate that minimal interfacial tension can only be observed when the spontaneous curvature is nearly zero.
    Language English
    Publishing date 2023-08-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2005937-1
    ISSN 1520-5827 ; 0743-7463
    ISSN (online) 1520-5827
    ISSN 0743-7463
    DOI 10.1021/acs.langmuir.3c01565
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Craniotomy hematoma was removed from the bone flap and multiple holes were drilled on the bone flap: A case report.

    Zhu, Wei / Ma, Lei / Li, Tuo / Chen, Hongguang

    Medicine

    2023  Volume 102, Issue 21, Page(s) e33781

    Abstract: Background: Chronic subdural hematoma (CSDH) is a common disease in neurosurgery department. Burr-hole drainage is the main surgical treatment. And the recurrence rate is as high as 25%.: Case report: In this case, a male patient with CSDH in the ... ...

    Abstract Background: Chronic subdural hematoma (CSDH) is a common disease in neurosurgery department. Burr-hole drainage is the main surgical treatment. And the recurrence rate is as high as 25%.
    Case report: In this case, a male patient with CSDH in the left frontotemporal parietal region underwent 2 drilling and drainage operations in the local hospital, but the hematoma recurred after operations. Being unable to bearing the repeated and progressive aggravation of headache, he came to our hospital for treatment. After considering the comprehensive situation, we use a new surgical method, removal of hematoma by drilling multiple holes in the lateral skull, to cure the patient.
    Conclusions: We get inspirations from the treatment of moyamoya disease surgery, through the bone holes the scalp forms many "meat column" like structures which have powerful capability in absorption, so the scalp could deep into the hematoma, then the CSDH could be cured. Provide a new surgical method for the treatment of refractory CSDH.
    MeSH term(s) Humans ; Male ; Craniotomy/adverse effects ; Craniotomy/methods ; Trephining/adverse effects ; Drainage/methods ; Headache ; Skull/surgery ; Hematoma, Subdural, Chronic/surgery ; Recurrence ; Treatment Outcome
    Language English
    Publishing date 2023-05-24
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000033781
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Experimental Investigation on Hover Performance of a Ducted Coaxial-Rotor UAV.

    Li, Hai / Chen, Zaibin / Jia, Hongguang

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 14

    Abstract: This paper presents experimental investigations on aerodynamic performance of a ducted coaxial-rotor system to evaluate its potential application as a small unmanned aerial vehicle (SUAV). Aimed at determining the influence of design parameters (rotor ... ...

    Abstract This paper presents experimental investigations on aerodynamic performance of a ducted coaxial-rotor system to evaluate its potential application as a small unmanned aerial vehicle (SUAV). Aimed at determining the influence of design parameters (rotor spacing, tip clearance and rotor position within the duct) on hover performance, a variety of systematic measurements for several correlative configurations (single/coaxial rotor with or without a duct) in terms of thrust and torque, as well as power, were conducted in an attempt to identify a better aerodynamic configuration. The experimental results for the coaxial-rotor system indicated that varying rotor spacing affected the thrust-sharing proportion between the two rotors, but this had no significant effect on the propulsive efficiency. The optimal H/R ratio was identified as being 0.40, due to a larger thrust and stronger stability in the case of identical rotation speeds. As for the ducted single-rotor configuration, the tip clearance played a dominant role in improving its thrust performance, especially for smaller gaps (δ≤0.015R), while the rotor position made subordinate contributions. The maximum performance was obtained with the rotor located at the P
    Language English
    Publishing date 2023-07-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23146413
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