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  1. Article ; Online: Environmental Impact of Bronchoscopy: Analysis of Waste Mass and Recyclability of Bronchoscopic Equipment and Consumables.

    Patrucco, Filippo / Gavelli, Francesco / Balbo, Piero Emilio

    Respiration; international review of thoracic diseases

    2023  Volume 102, Issue 10, Page(s) 905–911

    Abstract: Background: Greenhouse gases (GHGs) are significant contributors to climate change, and CO2 equivalent (CO2-e) is measured to compare emissions from GHGs. The healthcare sector contributes 4.4% of global CO2-e emissions, mainly with energy consumption ... ...

    Abstract Background: Greenhouse gases (GHGs) are significant contributors to climate change, and CO2 equivalent (CO2-e) is measured to compare emissions from GHGs. The healthcare sector contributes 4.4% of global CO2-e emissions, mainly with energy consumption and, in lesser extent, waste production. In this regard, bronchoscopy procedures produce a large amount of waste and are responsible for a significant consumption of energy.
    Objective: We aimed at quantifying the impact on waste mass production, energy consumption, and recyclability of bronchoscopic procedures.
    Methods: We conducted a prospective single-centre observational study; for each type of procedure (performed with either reusable or single-use instruments), the number of items used, their weight, and recyclability were evaluated, as well as the material of which recyclable waste was made of. We then calculated the total amount of waste produced, its recyclability, energy consumption, and CO2-e produced over 10 days of activity in our Interventional Pulmonology Unit.
    Results: Sixty procedures generated 61,928 g of waste, of which only 15.8% was potentially recyclable. Single-use instruments generated nearly twofold more recyclable waste than reusable ones, 80% during the procedure phase. Reusable instruments generated 45% of waste during the reprocessing phase, of which 50% was recyclable. The recyclable material was totally composed of paper and plastic. During 10 days of activity, we consumed 64 kWh and produced more than 67 kg of CO2-e due to non-recyclable waste and energy consumption.
    Conclusions: Our results confirm the compelling need to recycle as many materials as possible, even if the amount of recyclable waste is limited. In this respect, official documents issued by international societies are urgently needed to align our activity with climate requirements and improve the sustainability of our work.
    MeSH term(s) Humans ; Carbon Dioxide ; Bronchoscopy ; Prospective Studies ; Environment
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2023-09-19
    Publishing country Switzerland
    Document type Observational Study ; Journal Article
    ZDB-ID 206674-9
    ISSN 1423-0356 ; 0025-7931
    ISSN (online) 1423-0356
    ISSN 0025-7931
    DOI 10.1159/000533706
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Central venous pressure in critically ill patients: do we still need it?

    Gavelli, Francesco / Patrucco, Filippo / DE Vita, Nello / Solidoro, Paolo / Avanzi, Gian C

    Panminerva medica

    2023  Volume 66, Issue 1, Page(s) 1–3

    MeSH term(s) Humans ; Central Venous Pressure ; Critical Illness ; Intensive Care Units
    Language English
    Publishing date 2023-12-12
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123572-2
    ISSN 1827-1898 ; 0031-0808
    ISSN (online) 1827-1898
    ISSN 0031-0808
    DOI 10.23736/S0031-0808.23.05082-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Could the Glycemic Gap Fill the Unfilled Gaps?

    Gavelli, Francesco / Patrucco, Filippo

    Indian journal of endocrinology and metabolism

    2019  Volume 23, Issue 1, Page(s) 171

    Language English
    Publishing date 2019-03-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2600211-5
    ISSN 2230-9500 ; 2230-8210
    ISSN (online) 2230-9500
    ISSN 2230-8210
    DOI 10.4103/ijem.IJEM_617_18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Idiopathic Pulmonary Fibrosis and Post-COVID-19 Lung Fibrosis: Links and Risks.

    Patrucco, Filippo / Solidoro, Paolo / Gavelli, Francesco / Apostolo, Daria / Bellan, Mattia

    Microorganisms

    2023  Volume 11, Issue 4

    Abstract: Idiopathic pulmonary fibrosis (IPF) is considered the paradigmatic example of chronic progressive fibrosing disease; IPF does not result from a primary immunopathogenic mechanism, but immune cells play a complex role in orchestrating the fibrosing ... ...

    Abstract Idiopathic pulmonary fibrosis (IPF) is considered the paradigmatic example of chronic progressive fibrosing disease; IPF does not result from a primary immunopathogenic mechanism, but immune cells play a complex role in orchestrating the fibrosing response. These cells are activated by pathogen-associated or danger-associated molecular patterns generating pro-fibrotic pathways or downregulating anti-fibrotic agents. Post-COVID pulmonary fibrosis (PCPF) is an emerging clinical entity, following SARS-CoV-2 infection; it shares many clinical, pathological, and immune features with IPF. Similarities between IPF and PCPF can be found in intra- and extracellular physiopathological pro-fibrotic processes, genetic signatures, as well as in the response to antifibrotic treatments. Moreover, SARS-CoV-2 infection can be a cause of acute exacerbation of IPF (AE-IPF), which can negatively impact on IPF patients' prognosis. In this narrative review, we explore the pathophysiological aspects of IPF, with particular attention given to the intracellular signaling involved in the generation of fibrosis in IPF and during the SARS-CoV-2 infection, and the similarities between IPF and PCPF. Finally, we focus on COVID-19 and IPF in clinical practice.
    Language English
    Publishing date 2023-03-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11040895
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Comment on: Endobronchial biopsy in the final diagnosis of chronic obstructive pulmonary disease and asthma: a clinicopathological study.

    Gavelli, Francesco / Patrucco, Filippo

    Annals of Saudi medicine

    2019  Volume 39, Issue 3, Page(s) 209

    MeSH term(s) Asthma ; Biopsy ; Humans ; Pulmonary Disease, Chronic Obstructive
    Language English
    Publishing date 2019-05-30
    Publishing country Saudi Arabia
    Document type Letter ; Comment
    ZDB-ID 639014-6
    ISSN 0975-4466 ; 0256-4947
    ISSN (online) 0975-4466
    ISSN 0256-4947
    DOI 10.5144/0256-4947.2019.209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Diabetes and tuberculosis: A closer and closer relationship.

    Gavelli, Francesco / Patrucco, Filippo

    The clinical respiratory journal

    2018  Volume 12, Issue 11, Page(s) 2622–2623

    MeSH term(s) Diabetes Mellitus/epidemiology ; Humans ; Prevalence ; Tuberculosis/epidemiology
    Language English
    Publishing date 2018-10-24
    Publishing country England
    Document type Letter
    ZDB-ID 2442214-9
    ISSN 1752-699X ; 1752-6981
    ISSN (online) 1752-699X
    ISSN 1752-6981
    DOI 10.1111/crj.12962
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Management of sepsis and septic shock in the emergency department.

    Gavelli, Francesco / Castello, Luigi Mario / Avanzi, Gian Carlo

    Internal and emergency medicine

    2021  Volume 16, Issue 6, Page(s) 1649–1661

    Abstract: Early management of sepsis and septic shock is crucial for patients' prognosis. As the Emergency Department (ED) is the place where the first medical contact for septic patients is likely to occur, emergency physicians play an essential role in the early ...

    Abstract Early management of sepsis and septic shock is crucial for patients' prognosis. As the Emergency Department (ED) is the place where the first medical contact for septic patients is likely to occur, emergency physicians play an essential role in the early phases of patient management, which consists of accurate initial diagnosis, resuscitation, and early antibiotic treatment. Since the issuing of the Surviving Sepsis Campaign guidelines in 2016, several studies have been published on different aspects of sepsis management, adding a substantial amount of new information on the pathophysiology and treatment of sepsis and septic shock. In light of this emerging evidence, the present narrative review provides a comprehensive account of the recent advances in septic patient management in the ED.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Disease Management ; Emergency Service, Hospital/organization & administration ; Emergency Service, Hospital/statistics & numerical data ; Fluid Therapy/methods ; Fluid Therapy/trends ; Humans ; Monitoring, Physiologic/methods ; Resuscitation/methods ; Resuscitation/trends ; Sepsis/physiopathology ; Sepsis/therapy ; Shock, Septic/physiopathology ; Shock, Septic/therapy ; Vasoconstrictor Agents/pharmacology ; Vasoconstrictor Agents/therapeutic use
    Chemical Substances Anti-Bacterial Agents ; Vasoconstrictor Agents
    Language English
    Publishing date 2021-04-22
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-021-02735-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Diabetes and acute respiratory failure. Is the lung finally safe?

    Gavelli, Francesco / Patrucco, Filippo / Bellan, Mattia

    International journal of critical illness and injury science

    2019  Volume 9, Issue 1, Page(s) 49–50

    Language English
    Publishing date 2019-03-27
    Publishing country India
    Document type Journal Article
    ZDB-ID 2638865-0
    ISSN 2231-5004 ; 2229-5151
    ISSN (online) 2231-5004
    ISSN 2229-5151
    DOI 10.4103/IJCIIS.IJCIIS_73_18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Comment on

    Francesco Gavelli / Filippo Patrucco

    Annals of Saudi Medicine, Vol 39, Iss 3, Pp 209-

    Endobronchial biopsy in the final diagnosis of chronic obstructive pulmonary disease and asthma: a clinicopathological study

    2019  Volume 209

    Keywords Medicine ; R
    Language English
    Publishing date 2019-05-01T00:00:00Z
    Publisher King Faisal Specialist Hospital and Research Centre
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: How can CO

    Gavelli, Francesco / Teboul, Jean-Louis / Monnet, Xavier

    Journal of thoracic disease

    2019  Volume 11, Issue Suppl 11, Page(s) S1528–S1537

    Abstract: Assessing the adequacy of oxygen delivery with oxygen requirements is one of the key-goal of haemodynamic resuscitation. Clinical examination, lactate and central or mixed venous oxygen saturation ( ... ...

    Abstract Assessing the adequacy of oxygen delivery with oxygen requirements is one of the key-goal of haemodynamic resuscitation. Clinical examination, lactate and central or mixed venous oxygen saturation (S
    Language English
    Publishing date 2019-08-01
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd.2019.07.10
    Database MEDical Literature Analysis and Retrieval System OnLINE

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