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  1. Article: Exploring User Perspectives of and Ethical Experiences With Teletherapy Apps: Qualitative Analysis of User Reviews.

    Jo, Eunkyung / Kouaho, Whitney-Jocelyn / Schueller, Stephen M / Epstein, Daniel A

    JMIR mental health

    2023  Volume 10, Page(s) e49684

    Abstract: Background: Teletherapy apps have emerged as a promising alternative to traditional in-person therapy, especially after the COVID-19 pandemic, as they help overcome a range of geographical and emotional barriers to accessing care. However, the rapid ... ...

    Abstract Background: Teletherapy apps have emerged as a promising alternative to traditional in-person therapy, especially after the COVID-19 pandemic, as they help overcome a range of geographical and emotional barriers to accessing care. However, the rapid proliferation of teletherapy apps has occurred in an environment in which development has outpaced the various regulatory and ethical considerations of this space. Thus, researchers have raised concerns about the ethical implications and potential risks of teletherapy apps given the lack of regulation and oversight. Teletherapy apps have distinct aims to more directly replicate practices of traditional care, as opposed to mental health apps, which primarily provide supplemental support, suggesting a need to examine the ethical considerations of teletherapy apps from the lens of existing ethical guidelines for providing therapy.
    Objective: In this study, we examined user reviews of commercial teletherapy apps to understand user perceptions of whether and how ethical principles are followed and incorporated.
    Methods: We identified 8 mobile apps that (1) provided teletherapy on 2 dominant mobile app stores (Google Play and Apple App Store) and (2) had received >5000 app reviews on both app stores. We wrote Python scripts (Python Software Foundation) to scrape user reviews from the 8 apps, collecting 3268 user reviews combined across 2 app stores. We used thematic analysis to qualitatively analyze user reviews, developing a codebook drawing from the ethical codes of conduct for psychologists, psychiatrists, and social workers.
    Results: The qualitative analysis of user reviews revealed the ethical concerns and opportunities of teletherapy app users. Users frequently perceived unprofessionalism in their teletherapists, mentioning that their therapists did not listen to them, were distracted during therapy sessions, and did not keep their appointments. Users also noted technical glitches and therapist unavailability on teletherapy apps that might affect their ability to provide continuity of care. Users held varied opinions on the affordability of those apps, with some perceiving them as affordable and others not. Users further brought up that the subscription model resulted in unfair pricing and expressed concerns about the lack of cost transparency. Users perceived that these apps could help promote access to care by overcoming geographical and social constraints.
    Conclusions: Our study suggests that users perceive commercial teletherapy apps as adhering to many ethical principles pertaining to therapy but falling short in key areas regarding professionalism, continuity of care, cost fairness, and cost transparency. Our findings suggest that, to provide high-quality care, teletherapy apps should prioritize fair compensation for therapists, develop more flexible and transparent payment models, and invest in measures to ensure app stability and therapist availability. Future work is needed to develop standards for teletherapy and improve the quality and accessibility of those services.
    Language English
    Publishing date 2023-09-22
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2798262-2
    ISSN 2368-7959
    ISSN 2368-7959
    DOI 10.2196/49684
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Persistent Inflammation, Stem Cell-Induced Systemic Anti-Inflammatory Effects, and Need for Repeated Stem Cell Injections: Critical Concepts Influencing Optimal Stem Cell Strategies for Treating Acute Myocardial Infarction and Heart Failure.

    Epstein, Stephen E / Lipinski, Michael J / Luger, Dror

    Journal of the American Heart Association

    2018  Volume 7, Issue 4

    MeSH term(s) Anti-Inflammatory Agents ; Heart Failure ; Humans ; Inflammation ; Myocardial Infarction ; Stem Cells
    Chemical Substances Anti-Inflammatory Agents
    Language English
    Publishing date 2018-02-13
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.118.008524
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The inaugural United States World Hospice and Palliative Care Day Celebration: A virtual coming together.

    Rosa, William E / Pandey, Shila / Epstein, Andrew S / Connor, Stephen R / Nelson, Judith E

    Palliative & supportive care

    2021  Volume 19, Issue 2, Page(s) 182–186

    Abstract: Objective: On October 10, 2020, the Memorial Sloan Kettering Cancer Center Supportive Care Service hosted their first-ever United States (US) World Hospice and Palliative Care Day (WHPCD) Celebration. The purpose of this article is to describe the US ... ...

    Abstract Objective: On October 10, 2020, the Memorial Sloan Kettering Cancer Center Supportive Care Service hosted their first-ever United States (US) World Hospice and Palliative Care Day (WHPCD) Celebration. The purpose of this article is to describe the US inaugural event in alignment with the broader goals of WHPCD and provide lessons learned in anticipation of the second annual conference to be held on October 5-6, 2021.
    Methods: Description of the inaugural event in the context of COVID-19 and WHPCD, co-planning conference team reflection, and attendee survey responses.
    Results: The Worldwide Hospice Palliative Care Alliance initially launched WHPCD in 2005 as an annual unified day of action to celebrate and support hospice and palliative care around the world. The US-based innovative virtual conference featured 23 interprofessional hospice and palliative care specialists and patient and family caregiver speakers across nine diverse sessions addressing priorities at the intersection of COVID-19, social injustice, and the global burden of serious health-related suffering. Two primary aims guided the event: community building and wisdom sharing. Nearly 270 registrants from at least 16 countries and one dozen states across the US joined the free program focused on both personal and professional development.
    Significance of results: Unlike many other academic conferences and professional gatherings that were relegated to online forums due to pandemic-related restrictions, the US WHPCD Celebration was intentionally established to create a virtual coming together for collective reflection on the barriers and facilitators of palliative care delivery amid vast societal change. The goal to ensure a globally relevant and culturally inclusive agenda will continue to draw increased participation at an international level during future annual events. Finally, the transparent and respectful sharing of palliative care team experiences in the year preceding the conference established a safe environment for both individual expression and scholarly discussion.
    MeSH term(s) Anniversaries and Special Events ; COVID-19/epidemiology ; Hospice Care/organization & administration ; Hospice and Palliative Care Nursing/organization & administration ; Hospices/organization & administration ; Humans ; Palliative Care/organization & administration ; United States
    Language English
    Publishing date 2021-02-10
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2454009-2
    ISSN 1478-9523 ; 1478-9515
    ISSN (online) 1478-9523
    ISSN 1478-9515
    DOI 10.1017/S1478951521000237
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Calcium channel blockers

    Epstein, Stephen E.

    present status and future directions ; symp. held Nov. 17-19, 1983, in Carlsbad, Calif

    (The American journal of cardiology ; 55,3)

    1985  

    Title variant Calcium-channel blockers
    Author's details ed.: Stephen E. Epstein
    Series title The American journal of cardiology ; 55,3
    Keywords Calcium Channel Blockers / therapeutic use / congresses
    Size S. 1B - 221B
    Publisher Dun-Donnelley
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT004677776
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: "My mom calls it Annaland": A Qualitative Study of Phenomenology, Daily Life Impacts, and Treatment Considerations of Sluggish Cognitive Tempo.

    Becker, Stephen P / Fredrick, Joseph W / Foster, Josalyn A / Yeaman, Kiley M / Epstein, Jeffery N / Froehlich, Tanya E / Mitchell, John T

    Journal of attention disorders

    2021  Volume 26, Issue 6, Page(s) 915–931

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adolescent ; Attention Deficit Disorder with Hyperactivity/psychology ; Child ; Cognition ; Humans ; Parents ; Qualitative Research ; Sluggish Cognitive Tempo
    Language English
    Publishing date 2021-10-08
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2004350-8
    ISSN 1557-1246 ; 1087-0547
    ISSN (online) 1557-1246
    ISSN 1087-0547
    DOI 10.1177/10870547211050946
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Third Annual US Celebration of World Hospice and Palliative Care Day: A virtual coming together to unify the global palliative care community.

    Rosa, William E / Pandey, Shila / Epstein, Andrew S / Connor, Stephen R / Andersen, Laurie J / Blackler, Liz / Desai, Anjali V / Koranteng, Lauren Akua / Breitbart, William S / Nelson, Judith E

    Palliative & supportive care

    2023  Volume 21, Issue 3, Page(s) 378–384

    Abstract: Objectives: On 3-4 October 2022, the Memorial Sloan Kettering Cancer Center Supportive Care Service and Department of Psychiatry and Behavioral Sciences hosted the Third Annual United States (US) Celebration of World Hospice and Palliative Care Day ( ... ...

    Abstract Objectives: On 3-4 October 2022, the Memorial Sloan Kettering Cancer Center Supportive Care Service and Department of Psychiatry and Behavioral Sciences hosted the Third Annual United States (US) Celebration of World Hospice and Palliative Care Day (WHPCD). The purpose of this article is to reflect on the event within the broader context of the international WHPCD theme: "healing hearts and communities." We describe lessons learned in anticipation of the fourth annual conference to be held on 3-4 October 2023.
    Methods: Description of the third annual event, conference planning team reflection, and attendee evaluation responses.
    Results: The Worldwide Hospice Palliative Care Alliance launched WHPCD in 2005 as an annual unified day of action to celebrate and support hospice and palliative care globally. Since 2020, the conference has attracted an increasing number of attendees from around the world. Two primary aims continue to guide the event: community building and wisdom sharing. Fifty-two interprofessional palliative care experts, advocates, patients, and caregivers provided 13 unique interactive sessions. Four hundred and fifty-eight multidisciplinary registrants from at least 17 countries joined the program. Free registration for colleagues in low- and middle-income countries, students and trainees, and individuals experiencing financial hardship remains a cornerstone of inclusion and equitable access to the event.
    Significance of results: The US WHPCD celebration provides a virtual platform that offers opportunities for scientific dissemination and collective reflection on hospice and palliative care delivery amid significant local and global changes in clinical practice, research, policy and advocacy, and population health. We remain committed to ensuring an internationally relevant, culturally diverse, and multidisciplinary agenda that will continue to draw increased participation worldwide during future annual events.
    MeSH term(s) Humans ; United States ; Palliative Care ; Hospices ; Hospice Care ; Delivery of Health Care ; Hospice and Palliative Care Nursing
    Language English
    Publishing date 2023-04-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2454009-2
    ISSN 1478-9523 ; 1478-9515
    ISSN (online) 1478-9523
    ISSN 1478-9515
    DOI 10.1017/S1478951523000391
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Parents, but not their children, demonstrate greater delay discounting with resource scarcity.

    Button, Alyssa M / Paluch, Rocco A / Schechtman, Kenneth B / Wilfley, Denise E / Geller, Nancy / Quattrin, Teresa / Cook, Stephen R / Eneli, Ihouma U / Epstein, Leonard H

    BMC public health

    2023  Volume 23, Issue 1, Page(s) 1983

    Abstract: ... on immediate gratification. Delay discounting is reliably related to indicators of economic scarcity (i.e ...

    Abstract Background: Individuals with obesity tend to discount the future (delay discounting), focusing on immediate gratification. Delay discounting is reliably related to indicators of economic scarcity (i.e., insufficient resources), including lower income and decreased educational attainment in adults. It is unclear whether the impact of these factors experienced by parents also influence child delay discounting between the ages of 8 and 12-years in families with obesity.
    Methods: The relationship between indices of family income and delay discounting was studied in 452 families with parents and 6-12-year-old children with obesity. Differences in the relationships between parent economic, educational and Medicaid status, and parent and child delay discounting were tested.
    Results: Results showed lower parent income (p = 0.019) and Medicaid status (p = 0.021) were differentially related to greater parent but not child delay discounting among systematic responders.
    Conclusions: These data suggest differences in how indicators of scarcity influence delay discounting for parents and children, indicating that adults with scarce resources may be shaped to focus on immediate needs instead of long-term goals. It is possible that parents can reduce the impact of economic scarcity on their children during preadolescent years. These findings suggest a need for policy change to alleviate the burden of scarce conditions and intervention to modify delay discounting rate and to improve health-related choices and to address weight disparities.
    MeSH term(s) Adult ; Humans ; Child ; Delay Discounting ; Obesity ; Parents ; Income
    Language English
    Publishing date 2023-10-12
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-16832-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Large Animal Model Efficacy Testing Is Needed Prior to Launch of a Stem Cell Clinical Trial: An Evidence-Lacking Conclusion Based on Conjecture.

    Epstein, Stephen E / Luger, Dror / Lipinski, Michael J

    Circulation research

    2017  Volume 121, Issue 5, Page(s) 496–498

    MeSH term(s) Animals ; Clinical Trials as Topic/methods ; Disease Models, Animal ; Evidence-Based Medicine/methods ; Humans ; Mesenchymal Stem Cell Transplantation/methods ; Stem Cells/physiology ; Swine ; Treatment Outcome
    Language English
    Publishing date 2017-08-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.117.311562
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Paracrine-Mediated Systemic Anti-Inflammatory Activity of Intravenously Administered Mesenchymal Stem Cells: A Transformative Strategy for Cardiac Stem Cell Therapeutics.

    Epstein, Stephen E / Luger, Dror / Lipinski, Michael J

    Circulation research

    2017  Volume 121, Issue 9, Page(s) 1044–1046

    MeSH term(s) Animals ; Cardiovascular Diseases/immunology ; Cardiovascular Diseases/therapy ; Humans ; Inflammation/prevention & control ; Injections, Intravenous/methods ; Mesenchymal Stem Cell Transplantation/methods ; Mesenchymal Stem Cells/immunology ; Myocardium/immunology ; Paracrine Communication
    Language English
    Publishing date 2017-10-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.117.311925
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Trends in Costs of Care for Medicare Beneficiaries Treated in the Emergency Department From 2011 to 2016.

    Burke, Laura G / Burke, Ryan C / Epstein, Stephen K / Orav, E John / Jha, Ashish K

    JAMA network open

    2020  Volume 3, Issue 8, Page(s) e208229

    Abstract: Importance: There is little evidence regarding how total costs of care associated with an emergency department (ED) visit have changed, despite increasing policy focus on the value of acute care.: Objective: To examine trends in total standardized 30- ...

    Abstract Importance: There is little evidence regarding how total costs of care associated with an emergency department (ED) visit have changed, despite increasing policy focus on the value of acute care.
    Objective: To examine trends in total standardized 30-day costs of care associated with an ED visit.
    Design, setting, and participants: This cross-sectional study of 14 113 088 ED visits at 4730 EDs from 2011 to 2016 included a 20% national sample of traditional Medicare beneficiaries aged 65 years and older. Data analysis was conducted from August 2018 to April 2020.
    Exposures: Time (year) as a continuous variable.
    Main outcomes and measures: Trends in disposition from the ED and 30-day total standardized costs for all ED visits as well as the following spending components: index visit cost, physician costs, subsequent ED visit costs, subsequent inpatient costs, subsequent observation costs, non-ED outpatient care, postacute care, and aggregated total spending after the index ED visit.
    Results: The analytic sample consisted of 14 113 088 ED visits at 4730 EDs. The mean (SD) beneficiary age was 78.6 (8.6) years, 8 573 652 visits (60.7%) were among women, and 11 908 691 visits (84.7%) were among white patients. The proportion of patients discharged from the ED rose from 1 233 701 of 2 309 563 visits (53.4%) in 2011 to 1 279 701 of 2 268 363 visits (56.4%) in 2016. Total adjusted 30-day standardized costs of care declined from a mean (SE) of $8851 ($35.3) in 2011 to a mean (SE) of $8143 ($35.4) in 2016 (-$126/y; 95% CI, -$130 to -$121; P < .001) for all ED visits. This decrease was primarily associated with a decline in total spending on the index ED visit (-$48/y; 95% CI, -$50 to -$47; P < .001) as well as lower spending on postacute care (-$42/y; 95% CI, -$44 to -$41; P < .001) and subsequent inpatient care (-$34/y; 95% CI, -$36 to -$32; P < .001). There was an increase in spending after the index visit on downstream observation care ($3.6/y; 95% CI, $3.5 to $3.7; P < .001), outpatient ED care ($4.6/y; 95% CI, $4.4 to $4.8; P < .001), and other outpatient care ($15/y; 95% CI, $12 to $18; P < .001).
    Conclusions and relevance: In this study, total 30-day standardized costs of ED care for Medicare beneficiaries decreased in recent years. It may be that more intensive ED spending up front is associated with reductions in total costs of an acute episode.
    MeSH term(s) Aged ; Aged, 80 and over ; Cross-Sectional Studies ; Emergency Service, Hospital/economics ; Female ; Health Care Costs/statistics & numerical data ; Hospitalization/economics ; Hospitalization/statistics & numerical data ; Humans ; Male ; Medicare/economics ; Medicare/statistics & numerical data ; Patient Discharge ; United States/epidemiology
    Language English
    Publishing date 2020-08-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2020.8229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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