LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 3362

Search options

  1. Article: MODELING STREAMFLOW AND WATER QUALITY SENSITIVITY TO CLIMATE CHANGE AND URBAN DEVELOPMENT IN 20 U.S. WATERSHEDS.

    Johnson, T / Butcher, J / Deb, D / Faizullabhoy, M / Hummel, P / Kittle, J / McGinnis, S / Mearns, L O / Nover, D / Parker, A / Sarkar, S / Srinivasan, R / Tuppad, P / Warren, M / Weaver, C / Witt, J

    Journal of the American Water Resources Association

    2022  Volume 51, Issue 5, Page(s) 1321–1341

    Abstract: Watershed modeling in 20 large, United States (U.S.) watersheds addresses gaps in our knowledge ... downscaled climate model output. Urban and residential development scenarios are from U.S ... of streamflow and water quality responses to mid-21st Century climate change across the U.S. Simulated changes ...

    Abstract Watershed modeling in 20 large, United States (U.S.) watersheds addresses gaps in our knowledge of streamflow, nutrient (nitrogen and phosphorus), and sediment loading sensitivity to mid-21st Century climate change and urban/residential development scenarios. Use of a consistent methodology facilitates regional scale comparisons across the study watersheds. Simulations use the Soil and Water Assessment Tool. Climate change scenarios are from the North American Regional Climate Change Assessment Program dynamically downscaled climate model output. Urban and residential development scenarios are from U.S. Environmental Protection Agency's Integrated Climate and Land Use Scenarios project. Simulations provide a plausible set of streamflow and water quality responses to mid-21st Century climate change across the U.S. Simulated changes show a general pattern of decreasing streamflow volume in the central Rockies and Southwest, and increases on the East Coast and Northern Plains. Changes in pollutant loads follow a similar pattern but with increased variability. Ensemble mean results suggest that by the mid-21st Century, statistically significant changes in streamflow and total suspended solids loads (relative to baseline conditions) are possible in roughly 30-40% of study watersheds. These proportions increase to around 60% for total phosphorus and total nitrogen loads. Projected urban/residential development, and watershed responses to development, are small at the large spatial scale of modeling in this study.
    Language English
    Publishing date 2022-01-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1380287-2
    ISSN 1093-474X
    ISSN 1093-474X
    DOI 10.1111/1752-1688.12308
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Children’s erythrocyte fatty acids are associated with the risk of islet autoimmunity

    Sari Niinistö / Iris Erlund / Hye-Seung Lee / Ulla Uusitalo / Irma Salminen / Carin Andrén Aronsson / Hemang M. Parikh / Xiang Liu / Sandra Hummel / Jorma Toppari / Jin-Xiong She / Åke Lernmark / Annette G. Ziegler / Marian Rewers / Beena Akolkar / Jeffrey P. Krischer / David Galas / Siba Das / Nikita Sakhanenko /
    Stephen S. Rich / William Hagopian / Jill M. Norris / Suvi M. Virtanen / the TEDDY Study Group

    Scientific Reports, Vol 11, Iss 1, Pp 1-

    2021  Volume 12

    Abstract: ... 2010 in the U.S., Finland, Sweden, and Germany. A nested case–control design comprised 398 cases ...

    Abstract Abstract Our aim was to investigate the associations between erythrocyte fatty acids and the risk of islet autoimmunity in children. The Environmental Determinants of Diabetes in the Young Study (TEDDY) is a longitudinal cohort study of children at high genetic risk for type 1 diabetes (n = 8676) born between 2004 and 2010 in the U.S., Finland, Sweden, and Germany. A nested case–control design comprised 398 cases with islet autoimmunity and 1178 sero-negative controls matched for clinical site, family history, and gender. Fatty acids composition was measured in erythrocytes collected at the age of 3, 6, and 12 months and then annually up to 6 years of age. Conditional logistic regression models were adjusted for HLA risk genotype, ancestry, and weight z-score. Higher eicosapentaenoic and docosapentaenoic acid (n − 3 polyunsaturated fatty acids) levels during infancy and conjugated linoleic acid after infancy were associated with a lower risk of islet autoimmunity. Furthermore, higher levels of some even-chain saturated (SFA) and monounsaturated fatty acids (MUFA) were associated with increased risk. Fatty acid status in early life may signal the risk for islet autoimmunity, especially n − 3 fatty acids may be protective, while increased levels of some SFAs and MUFAs may precede islet autoimmunity.
    Keywords Medicine ; R ; Science ; Q
    Subject code 571
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  3. Article ; Conference proceedings: Devil’s claw (Harpagophytum procumbens) – Pharmacokinetics of harpagoside in horses

    Axmann, S / Hummel, K / Nöbauer, K / Razzazi-Fazeli, E / Zitterl-Eglseer, K

    Planta Medica

    2019  Volume 85, Issue 18

    Event/congress 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP, Innsbruck, Austria, 2019-09-01
    Language German
    Publishing date 2019-12-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 123545-x
    ISSN 1439-0221 ; 0032-0943
    ISSN (online) 1439-0221
    ISSN 0032-0943
    DOI 10.1055/s-0039-3399645
    Database Thieme publisher's database

    More links

    Kategorien

  4. Article ; Online: Takayasu’s arteritis

    Klaus Empen / Astrid Hummel / Daniel Beug / Stephan B. Felix / Mathias C. Busch / Piotr M. Kaczmarek

    BMC Research Notes, Vol 10, Iss 1, Pp 1-

    a case with relapse after urgent coronary revascularization

    2017  Volume 3

    Abstract: ... myocardial ischemia. We report on a 24-year old patient with Takayasu’s arteritis who underwent urgent ... of Takayasu’s disease was made. The patient was treated with prednisolone and cyclophosphamide for 5 months ...

    Abstract Abstract Background Vasculitides are commonly unrecognized causes of coronary stenosis and myocardial ischemia. We report on a 24-year old patient with Takayasu’s arteritis who underwent urgent percutaneous coronary intervention, suffered from symptomatic restenosis of the left main coronary artery during standard immunosuppressive therapy. Case presentation A 24-year old woman was referred for coronary angiography because of typical progressive angina pectoris. On bicycle ergometry, there were both reproducible symptoms and deep ST segment depressions on precordial leads. Semi-selective angiography of the left coronary artery revealed high-grade ostial stenosis. Because of persistent angina pectoris and electrocardiographic signs of acute myocardial ischemia, immediate percutaneous coronary angioplasty with subsequent implantation of an everolimus-eluting stent was performed. This intervention was performed with excellent angiographic results. Because of several concomitant criteria including hypoechogenicity on postprocedural intravascular ultrasonography, the diagnosis of Takayasu’s disease was made. The patient was treated with prednisolone and cyclophosphamide for 5 months. Because of recurrent angina pectoris, another coronary angiography was performed, which revealed high-grade in-stent-restenosis. Immunomodulatory therapy was switched to high-dose prednisolone and the anti-IL-6 receptor antagonist tocilizumab. The high-grade in-stent-restenosis persisted, and aortocoronary bypass graft surgery was performed with two saphenous vein grafts to the left anterior descending and circumflex artery. Since then, the patient has been doing well for 2 years. Conclusion In cases of treatment refractoriness during standard immunosuppressive therapy, more recently developed biological compounds may offer an alternative strategy.
    Keywords Takayasu’s arteritis ; Vasculitis ; Immunosuppression ; Coronary intervention ; Case report ; Medicine ; R ; Biology (General) ; QH301-705.5 ; Science (General) ; Q1-390
    Subject code 610
    Language English
    Publishing date 2017-07-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  5. Article ; Online: Comment on: Minotti B, Blättler-Remund T, Sieber R, Tabakovic S. Nurse practitioners in emergency medicine: the Swiss experience.

    Grossmann, Florian F / Dreher-Hummel, Thomas / Allen, Deborah / Ulrich, Anja / Bingisser, Roland

    European journal of emergency medicine : official journal of the European Society for Emergency Medicine

    2020  Volume 27, Issue 5, Page(s) 389

    MeSH term(s) Emergency Medicine ; Humans ; Nurse Practitioners ; Switzerland
    Language English
    Publishing date 2020-08-27
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1233544-7
    ISSN 1473-5695 ; 0969-9546
    ISSN (online) 1473-5695
    ISSN 0969-9546
    DOI 10.1097/MEJ.0000000000000688
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Conference proceedings: MACC1 in esophageal and gastric adenocarcinomas (AGE/S): An aggressive but drugable oncogene

    Treese, C / Pahle, J / Winterfeld, M von / Berg, E / Hummel, M / Kobelt, D / Rau, B / Daberkow, O / Walther, W / Siegmund, B / Daum, S / Stein, U

    Zeitschrift für Gastroenterologie

    2018  Volume 56, Issue 08

    Event/congress Viszeralmedizin 2018 - 73. Jahrestagung der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten mit Sektion Endoskopie - 12. Herbsttagung der Deutschen Gesellschaft für Allgemein- und Viszeralchirurgie gemeinsam mit den Arbeitsgemeinschaften der DGAV, München, 2018-09-12
    Language English
    Publishing date 2018-08-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 201387-3
    ISSN 1439-7803 ; 0044-2771 ; 0172-8504
    ISSN (online) 1439-7803
    ISSN 0044-2771 ; 0172-8504
    DOI 10.1055/s-0038-1668918
    Database Thieme publisher's database

    More links

    Kategorien

  7. Book ; Thesis: Validierung eines Fragebogeninstrumentes zur Erfassung der Life-Space Mobilität bei hospitalisierten, geriatrischen Patient*innen mit und ohne kognitive Einschränkung

    Hummel, Saskia / Hauer, Klaus

    2023  

    Institution Universität Heidelberg
    Author's details vorgelegt von Saskia Elke Hummel ; Doktorvater: Prof. Dr. Klaus Hauer
    Language German
    Size 74 Blätter, Illustrationen
    Publishing place Heidelberg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Ruprecht-Karls-Universität Heidelberg, 2023
    HBZ-ID HT030643719
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  8. Book ; Online: Metagenomic Screening of ancient DNA from a Late Medieval mass burial site in Lübeck, Northern Germany, revealed occurence of S. Paratyphi C.

    Haller, Magdalena / Callan, Kimberly / Susat, Julian / Flux, Anna Lena / Immel, Alexander / Franke, Andre / Herbig, Alexander / Krause, Johannes / Kupczok, Anne / Fouquet, Gerhard / Hummel, Susanne / Rieger, Dirk / Nebel, Almut / Krause-Kyora, Ben

    2021  

    Abstract: In the Middle Ages, European settlements of all sizes were repeatedly affected by outbreaks of infectious diseases. A Late Medieval mass-burial site next to the Heiligen-Geist-Hospital (HGH) in Lübeck, a city of the Hanseatic League, contained the ... ...

    Abstract In the Middle Ages, European settlements of all sizes were repeatedly affected by outbreaks of infectious diseases. A Late Medieval mass-burial site next to the Heiligen-Geist-Hospital (HGH) in Lübeck, a city of the Hanseatic League, contained the skeletal remains of more than 800 individuals assumed to have died of an infectious disease, most probably of the plague. Metagenomic screening on ancient DNA extracts revealed evidence of an infection with Salmonella enterica subsp. enterica serovar Paratyphi C, suggesting an epidemic outbreak of enteric paratyphoid fever. Based on radiocarbon dates, we determined the enteric paratyphoid fever outbreak in Lübeck to have occurred between 1360 and 1400 CE, historical records indicating the year 1367 CE as the most probable date.

    Fifth major release of AncientMetagenomeDir Release v21.09 includes 9 new publications, representing 122 new ancient host-associated metagenome samples, 13 new ancient microbial genomes, and 12 new ancient environmental samples. This brings the repository to a total of 132 publications, 1038 new ancient host-associated metagenome samples, 368 ancient microbial genomes, and 375 new ancient environmental samples. Corrections were made to 3 publications. Thanks to the following contributors and reviewers: @Jesser11 @ivelsko @pheintzman @bbartholdy @MeriamOs Thanks to the following authors of added publications for answering queries: Jaelle Brealey, Miriam Bravo-López, and Barbara Moguel. The full changelog is below. Added Ancient Metagenome: Host Associated Ottoni 2021 10.1073/pnas.2102116118 Rampelli 2021b 10.1016/j.isci.2021.102816 Brealey 2021 10.1016/j.cub.2021.08.010 Ancient Single Genome: Host Associated Susat 2021 10.1016/j.celrep.2021.109278 Guzmán-Solis 2021 10.7554/eLife.68612 Ancient Metagenome: Environmental De Dios 2021 10.1016/j.isci.2021.103021 Campos 2021 10.1371/journal.ppat.1009714 Wu 2021 10.1371/journal.ppat.1009886 Ancient Metagenome: Environmental Moguel 2021 10.1038/s41598-021-92981-8 Ancient Metagenome: Anthropogenic Misc ...
    Keywords Homo sapiens
    Subject code 930
    Publisher Kiel University
    Publishing country nl
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  9. Book ; Thesis: Intestinaler Telomerverlust als Folge einer Transplant-gegen-Wirt-Reaktion nach allogener Stammzelltransplantation

    Hummel, Sebastian

    2018  

    Author's details vorgelegt von Sebastian Hummel
    Language German
    Size 105 Seiten, Illustrationen, Diagramme
    Publishing place Aachen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2018
    HBZ-ID HT019832460
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  10. Article: Geobotany in a fault in the world’s largest continuous wetland in central South America

    de Almeida, Teodoro Isnard Ribeiro / Cibele Hummel do Amaral / Moreno Botelho / Eduardo Francisco Ribeiro / Natasha Costa Penatti

    Wetlands ecology and management. 2019 Feb., v. 27, no. 1

    2019  

    Abstract: ... The entire dataset defines this geological structure as a driver of the Pantanal’s plant communities, being ...

    Abstract The Pantanal is located in the center of South America in a tectonically active sedimentary basin of Quaternary age. Even though the relief is flat and the diversity of the sediments is low, its vegetation cover has high variability resulting from seasonal fluctuations in water levels and the presence of four surrounding biomes. Changes in elevation of less than 1 m influence the length and intensity of floods, powerfully affecting the vegetation. Faults with small vertical displacement can generate abrupt vegetation changes and, consequently, expressive vegetation lineaments. This study characterizes a lineament in the northern Pantanal, considering Land Surface Phenology, estimates of precipitation, and floristic survey. The phenological metrics, obtained from a 15-year time series from the Moderate Resolution Imaging Spectroradiometer processed by TIMESAT software, discriminate evergreen forests in the NW of this lineament from savanna-like physiognomies in the SE region. Plant taxonomic identification shows two distinct regional strata with a clear separation between species adapted to prolonged floods in the NW and typical species of the Cerrado biome, mostly xeromorphic, in the SE. Data from the Tropical Rainfall Measuring Mission complemented the analysis, showing different dependence on local rains on different sides of the lineament. The entire dataset defines this geological structure as a driver of the Pantanal’s plant communities, being a boundary for the extensive establishment of propagules of the Amazon biome. This research, in addition to advancing knowledge of this singular region, which is essential for management studies, can be a stimulus to biological and forest investigations.
    Keywords basins ; cerrado ; computer software ; data collection ; ecosystems ; evergreen forests ; floods ; moderate resolution imaging spectroradiometer ; phenology ; phytogeography ; plant communities ; plant taxonomy ; rain ; seasonal variation ; sediments ; species identification ; surveys ; time series analysis ; vegetation cover ; wetlands ; Pantanal ; South America
    Language English
    Dates of publication 2019-02
    Size p. 171-185.
    Publishing place Springer Netherlands
    Document type Article
    ZDB-ID 20900-4
    ISSN 1572-9834 ; 0923-4861
    ISSN (online) 1572-9834
    ISSN 0923-4861
    DOI 10.1007/s11273-018-9650-7
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

To top