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Article ; Online: Psicotrópicos e Atenção Primária à Saúde

Bárbara Vukomanovic Molck / Guilherme Correa Barbosa / Thiago da Silva Domingos

Interface: Comunicação, Saúde, Educação, Vol

a subordinação da produção de cuidado à medicalização no contexto da Saúde da Família

2021 Volume 25

Abstract: Este estudo teve como objetivo compreender o fenômeno da medicalização e do uso de psicotrópicos em longo prazo com base na percepção dos usuários de uma Unidade de Saúde da Família (USF). Trata-se de um estudo qualitativo, fundamentado no método ... ...

Abstract	Este estudo teve como objetivo compreender o fenômeno da medicalização e do uso de psicotrópicos em longo prazo com base na percepção dos usuários de uma Unidade de Saúde da Família (USF). Trata-se de um estudo qualitativo, fundamentado no método autobiográfico e na narrativa do sujeito. Utilizou-se um roteiro para conduzir entrevistas semiestruturadas, realizadas com usuários intencionalmente selecionados. A análise temática possibilitou vislumbrar a incorporação da medicamentalização nas concepções de vida e de sofrimento dos usuários no contexto da Saúde da Família (SF), perspectiva que vai ao encontro da medicalização social e tem subsídio no modelo biomédico que subordina o processo de trabalho da Atenção Primária à Saúde (APS).
Keywords	Psicotrópicos ; Medicalização ; Atenção primária à saúde ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2021-02-01T00:00:00Z
Publisher	Faculdade de Medicina de Botucatu (Unesp)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Análise estrutural e funcional da rede social de usuários do Centro de Atenção Psicossocial

Giovanna Natal Amadei / Guilherme Correa Barbosa / Paula Hayasi Pinho / Márcia Aparecida Ferreira de Oliveira / Thiago da Silva Domingos

Interface: Comunicação, Saúde, Educação, Vol

caminhos para a Atenção Psicossocial

2023 Volume 27

Abstract: Resumo Objetivou-se analisar as características estruturais, as funções e os atributos dos vínculos, nas redes sociais, de usuários de um Centro de Atenção Psicossocial (Caps). Para isso, desenvolveu-se um estudo qualitativo em que participaram 16 ... ...

Abstract	Resumo Objetivou-se analisar as características estruturais, as funções e os atributos dos vínculos, nas redes sociais, de usuários de um Centro de Atenção Psicossocial (Caps). Para isso, desenvolveu-se um estudo qualitativo em que participaram 16 usuários de um Caps. Foram realizadas entrevistas em profundidade e semiestruturadas com base no diagrama do Mapa de Redes. Identificaram-se redes sociais extensas e com concentração de relações íntimas, circunscritas aos familiares e aos serviços de saúde. Após o adoecimento, os participantes relataram relações familiares fragilizadas. A apropriação dos espaços na comunidade e nas relações de amizade favoreceu a estruturação das redes. A análise do Mapa de Redes compreende uma ferramenta analisadora indicando, à produção do cuidado em Saúde Mental, os rumos para a Atenção Psicossocial.
Keywords	Atenção psicossocial ; Saúde mental ; Serviços comunitários de saúde mental ; Rede social ; Análise de rede social ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	Faculdade de Medicina de Botucatu (Unesp)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Trends in perioperative practices of high-risk surgical patients over a 10-year interval.

Gomes, Brenno Cardoso / Lobo, Suzana Margareth Ajeje / Sá Malbouisson, Luiz Marcelo / de Freitas Chaves, Renato Carneiro / Domingos Corrêa, Thiago / Prata Amendola, Cristina / Silva Júnior, João Manoel

PloS one

2023 Volume 18, Issue 9, Page(s) e0286385

Abstract: Introduction: In Brazil, data show an important decrease in morbi-mortality of high-risk surgical patients over a 10-year high. The objective of this post-hoc study was to evaluate the mechanism explaining this trend in high-risk surgical patients ... ...

Abstract	Introduction: In Brazil, data show an important decrease in morbi-mortality of high-risk surgical patients over a 10-year high. The objective of this post-hoc study was to evaluate the mechanism explaining this trend in high-risk surgical patients admitted to Brazilian ICUs in two large Brazilian multicenter cohort studies performed 10 years apart. Methods: The patients included in the 2 cohorts studies published in 2008 and 2018 were compared after a (1:1) propensity score matching. Patients included were adults who underwent surgeries and admitted to the ICU afterwards. Results: After matching, 704 patients were analyzed. Compared to the 2018 cohort, 2008 cohort had more postoperative infections (OR 13.4; 95%CI 6.1-29.3) and cardiovascular complications (OR 1.5; 95%CI 1.0-2.2), as well as a lower survival ICU stay (HR = 2.39, 95% CI: 1.36-4.20) and hospital stay (HR = 1.64, 95% CI: 1.03-2.62). In addition, by verifying factors strongly associated with hospital mortality, it was found that the risk of death correlated with higher intraoperative fluid balance (OR = 1.03, 95% CI 1.01-1.06), higher creatinine (OR = 1.31, 95% CI 1.1-1.56), and intraoperative blood transfusion (OR = 2.32, 95% CI 1.35-4.0). By increasing the mean arterial pressure, according to the limits of sample values from 43 mmHg to 118 mmHg, the risk of death decreased (OR = 0.97, 95% CI 0.95-0.98). The 2008 cohort had higher fluid balance, postoperative creatinine, and volume of intraoperative blood transfused and lower mean blood pressure at ICU admission and temperature at the end of surgery. Conclusion: In this sample of ICUs in Brazil, high-risk surgical patients still have a high rate of complications, but with improvement over a period of 10 years. There were changes in the management of these patients over time.
MeSH term(s)	Adult ; Humans ; Creatinine ; Brazil/epidemiology ; Hospital Mortality ; Hospitalization ; Hypotension
Chemical Substances	Creatinine (AYI8EX34EU)
Language	English
Publishing date	2023-09-19
Publishing country	United States
Document type	Multicenter Study ; Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0286385
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Regional venous-arterial CO

Corrêa, Thiago Domingos / Pereira, Adriano José / Takala, Jukka / Jakob, Stephan Mathias

Intensive care medicine experimental

2020 Volume 8, Issue 1, Page(s) 64

Abstract: Background: Venous-arterial carbon dioxide (CO: Objectives: To address determinants of systemic and renal, spleen, gut and liver Cv-aCO: Methods: Post hoc analysis of original data from published experimental studies aimed to address effects of ... ...

Abstract	Background: Venous-arterial carbon dioxide (CO Objectives: To address determinants of systemic and renal, spleen, gut and liver Cv-aCO Methods: Post hoc analysis of original data from published experimental studies aimed to address effects of different fluid resuscitation strategies on oxygen transport, lactate metabolism and organ dysfunction in fecal peritonitis and endotoxin infusion, and from animals in cardiac tamponade or hypoxic hypoxia. Systemic and regional hemodynamics, blood flow, lactate uptake, carbon dioxide and oxygen-derived variables were determined. Generalized estimating equations (GEE) were fit to assess contributors to systemic and regional Cv-aCO Results: Median (range) of pooled systemic Cv-aCO Conclusion: In a mixed set of animals in different shock forms or during hypoxic injury, hepatosplanchnic Cv-aCO
Language	English
Publishing date	2020-10-29
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2740385-3
ISSN	2197-425X
ISSN	2197-425X
DOI	10.1186/s40635-020-00353-9
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Article: Antimicrobial Stewardship Programs: A Review of Strategies to Avoid Polymyxins and Carbapenems Misuse in Low Middle-Income Countries.

de Carvalho, Fabrício Rodrigues Torres / Telles, João Paulo / Tuon, Felipe Francisco Bodan / Rabello Filho, Roberto / Caruso, Pedro / Correa, Thiago Domingos

Antibiotics (Basel, Switzerland)

2022 Volume 11, Issue 3

Abstract: Antibiotics misuse and overuse are concerning issues worldwide, especially in low middle-income countries. These practices contribute to the increasing rates of antimicrobial resistance. One efficient strategy to avoid them is antimicrobial stewardship ... ...

Abstract	Antibiotics misuse and overuse are concerning issues worldwide, especially in low middle-income countries. These practices contribute to the increasing rates of antimicrobial resistance. One efficient strategy to avoid them is antimicrobial stewardship programs. In this review, we focus on the possible approaches to spare the prescription of polymyxins and carbapenems for the treatment of
Language	English
Publishing date	2022-03-12
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2681345-2
ISSN	2079-6382
ISSN	2079-6382
DOI	10.3390/antibiotics11030378
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Article ; Online: A nationwide survey on health resources and clinical practices during the early COVID-19 pandemic in Brazil.

Campos, Pedro Paulo Zanella do Amaral / Souza, Guilherme Martins de / Midega, Thais / Guimarães, Hélio Penna / Corrêa, Thiago Domingos / Cordioli, Ricardo Luiz

Revista Brasileira de terapia intensiva

2022 Volume 34, Issue 1, Page(s) 107–115

Abstract: Objective: To evaluate clinical practices and hospital resource organization during the early COVID-19 pandemic in Brazil.: Methods: This was a multicenter, cross-sectional survey. An electronic questionnaire was provided to emergency department and ... ...

Title translation	Estudo nacional sobre recursos da saúde e práticas clínicas durante o início da pandemia da COVID-19 no Brasil.
Abstract	Objective: To evaluate clinical practices and hospital resource organization during the early COVID-19 pandemic in Brazil. Methods: This was a multicenter, cross-sectional survey. An electronic questionnaire was provided to emergency department and intensive care unit physicians attending COVID-19 patients. The survey comprised four domains: characteristics of the participants, clinical practices, COVID-19 treatment protocols and hospital resource organization. Results: Between May and June 2020, 284 participants [median (interquartile ranges) age 39 (33 - 47) years, 56.3% men] responded to the survey; 33% were intensivists, and 9% were emergency medicine specialists. Half of the respondents worked in public hospitals. Noninvasive ventilation (89% versus 73%; p = 0.001) and highflow nasal cannula (49% versus 32%; p = 0.005) were reported to be more commonly available in private hospitals than in public hospitals. Mechanical ventilation was more commonly used in public hospitals than private hospitals (70% versus 50%; p = 0,024). In the Emergency Departments, positive endexpiratory pressure was most commonly adjusted according to SpO2, while in the intensive care units, positive end-expiratory pressure was adjusted according to the best lung compliance. In the Emergency Departments, 25% of the respondents did not know how to set positive end-expiratory pressure. Compared to private hospitals, public hospitals had a lower availability of protocols for personal protection equipment during tracheal intubation (82% versus 94%; p = 0.005), managing mechanical ventilation [64% versus 75%; p = 0.006] and weaning patients from mechanical ventilation [34% versus 54%; p = 0.002]. Finally, patients spent less time in the emergency department before being transferred to the intensive care unit in private hospitals than in public hospitals [2 (1 - 3) versus 5 (2 - 24) hours; p < 0.001]. Conclusion: This survey revealed significant heterogeneity in the organization of hospital resources, clinical practices and treatments among physicians during the early COVID-19 pandemic in Brazil.
MeSH term(s)	Adult ; Brazil/epidemiology ; COVID-19/drug therapy ; COVID-19/therapy ; Cross-Sectional Studies ; Female ; Health Resources ; Humans ; Male ; Pandemics ; Surveys and Questionnaires
Language	English
Publishing date	2022-06-24
Publishing country	Brazil
Document type	Journal Article ; Multicenter Study
ZDB-ID	2732162-9
ISSN	1982-4335 ; 1982-4335
ISSN (online)	1982-4335
ISSN	1982-4335
DOI	10.5935/0103-507X.20220005-pt
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Article ; Online: Characteristics, risk factors, and outcomes of bloodstream

Hohmann, Fábio Barlem / Chaves, Renato Carneiro de Freitas / Olivato, Guilherme Benfatti / Souza, Guilherme Martins de / Galindo, Vinicius Barbosa / Silva, Moacyr / Martino, Marines Dalla Valle / Menezes, Fernando Gatti de / Corrêa, Thiago Domingos

The Journal of international medical research

2023 Volume 51, Issue 1, Page(s) 3000605221131122

Abstract: Objective: The main objective was to assess the clinical characteristics, associated factors, and outcomes of patients admitted to the ICU for candidemia. The secondary objective was to examine the relationship of candidemia with the length of stay and ... ...

Abstract	Objective: The main objective was to assess the clinical characteristics, associated factors, and outcomes of patients admitted to the ICU for candidemia. The secondary objective was to examine the relationship of candidemia with the length of stay and mortality. Methods: The analysis was a retrospective single-center cohort study addressing the effect of invasive candidemia on outcomes. This study was performed in a medical-surgical ICU located in a tertiary private hospital in São Paulo, Brazil. Data was collected through the review of the hospital database. Results: In total, 18,442 patients were included in our study, including 22 patients with candidemia. The median age was similar in patients with and without candidemia [67 (56-84) vs. 67 (51-80)]. Most patients were male, and the proportion of men was higher among patients with candidemia (77% vs. 55.3%). The rates of renal replacement therapy (40.9% vs. 3.3%), mechanical ventilation (63.6% vs. 29.6%), and parenteral nutrition (40.9% vs. 4.8%) were higher in patients with candidemia than in those without candidemia. The mortality rate (77.3% vs. 11.9%) and length of hospital stay [42 days (23.0-78.8) vs. 8 days (5.0-17.0)] were significantly higher in patients with candidemia. Conclusions: Patients with candidemia are prone to longer hospital stay and mortality. In addition, we found associations of candidemia with the use of invasive mechanical ventilation, renal replacement therapy, and parenteral nutrition.
MeSH term(s)	Humans ; Male ; Female ; Candida ; Candidemia/epidemiology ; Candidemia/drug therapy ; Retrospective Studies ; Cohort Studies ; Brazil/epidemiology ; Candidiasis/epidemiology ; Candidiasis/drug therapy ; Risk Factors ; Intensive Care Units ; Tertiary Care Centers ; Antifungal Agents/therapeutic use
Chemical Substances	Antifungal Agents
Language	English
Publishing date	2023-01-20
Publishing country	England
Document type	Journal Article
ZDB-ID	184023-x
ISSN	1473-2300 ; 0300-0605 ; 0142-2596
ISSN (online)	1473-2300
ISSN	0300-0605 ; 0142-2596
DOI	10.1177/03000605221131122
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Article ; Online: Characteristics, risk factors, and outcomes of bloodstream infections in the intensive care unit

Fábio Barlem Hohmann / Renato Carneiro de Freitas Chaves / Guilherme Benfatti Olivato / Guilherme Martins de Souza / Vinicius Barbosa Galindo / Moacyr Silva Jr / Marines Dalla Valle Martino / Fernando Gatti de Menezes / Thiago Domingos Corrêa

Journal of International Medical Research, Vol

a retrospective cohort study

2023 Volume 51

Abstract: Objective The main objective was to assess the clinical characteristics, associated factors, and outcomes of patients admitted to the ICU for candidemia. The secondary objective was to examine the relationship of candidemia with the length of stay and ... ...

Abstract	Objective The main objective was to assess the clinical characteristics, associated factors, and outcomes of patients admitted to the ICU for candidemia. The secondary objective was to examine the relationship of candidemia with the length of stay and mortality. Methods The analysis was a retrospective single-center cohort study addressing the effect of invasive candidemia on outcomes. This study was performed in a medical-surgical ICU located in a tertiary private hospital in São Paulo, Brazil. Data was collected through the review of the hospital database. Results In total, 18,442 patients were included in our study, including 22 patients with candidemia. The median age was similar in patients with and without candidemia [67 (56–84) vs. 67 (51–80)]. Most patients were male, and the proportion of men was higher among patients with candidemia (77% vs. 55.3%). The rates of renal replacement therapy (40.9% vs. 3.3%), mechanical ventilation (63.6% vs. 29.6%), and parenteral nutrition (40.9% vs. 4.8%) were higher in patients with candidemia than in those without candidemia. The mortality rate (77.3% vs. 11.9%) and length of hospital stay [42 days (23.0–78.8) vs. 8 days (5.0–17.0)] were significantly higher in patients with candidemia. Conclusions Patients with candidemia are prone to longer hospital stay and mortality. In addition, we found associations of candidemia with the use of invasive mechanical ventilation, renal replacement therapy, and parenteral nutrition.
Keywords	Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
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Article ; Online: In Response.

Zampieri, Fernando G / Kawano-Dourado, Leticia / Azevedo, Luciano Cesar Pontes / Corrêa, Thiago Domingos / Cavalcanti, Alexandre Biasi

Anesthesia and analgesia

2018 Volume 127, Issue 1, Page(s) 313–314

MeSH term(s)	Chlorides ; Critical Illness ; Humans
Chemical Substances	Chlorides
Language	English
Publishing date	2018-04-23
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	80032-6
ISSN	1526-7598 ; 0003-2999
ISSN (online)	1526-7598
ISSN	0003-2999
DOI	10.1213/ANE.0000000000003381
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Article ; Online: Impact of intensive care unit admission during handover on mortality: propensity matched cohort study.

Midega, Thais Dias / Leite Filho, Newton Carlos Viana / Nassar, Antonio Paulo / Alencar, Roger Monteiro / Capone Neto, Antonio / Ferraz, Leonardo José Rolim / Corrêa, Thiago Domingos

Einstein (Sao Paulo, Brazil)

2021 Volume 19, Page(s) eAO5748

Abstract: Objective: To investigate the impact of intensive care unit admission during medical handover on mortality.: Methods: Post-hoc analysis of data extracted from a prior study aimed at addressing the impacts of intensive care unit readmission on ... ...

Abstract	Objective: To investigate the impact of intensive care unit admission during medical handover on mortality. Methods: Post-hoc analysis of data extracted from a prior study aimed at addressing the impacts of intensive care unit readmission on clinical outcomes. This retrospective, single-center, propensity-matched cohort study was conducted in a 41-bed general open-model intensive care unit. Patients were assigned to one of two cohorts according to time of intensive care unit admission: Handover Group (intensive care unit admission between 6:30 am and 7:30 am or 6:30 pm and 7:30 pm) or Control Group (intensive care unit admission between 7:31 am and 6:29 pm or 7:31 pm and 6:29 am). Patients in the Handover Group were propensity-matched to patients in the Control Group at a 1:2 ratio. Results: A total of 6,650 adult patients were admitted to the intensive care unit between June 1st 2013 and May 31st 2015. Following exclusion of non-eligible participants, 5,779 patients (389; 6.7% and 5,390; 93.3%, Handover and Control Group) were deemed eligible for propensity score matching. Of these, 1,166 were successfully matched (389; 33.4% and 777; 66.6%, Handover and Control Group). Following propensity-score matching, intensive care unit admission during handover was not associated with increased risk of intensive care unit (OR: 1.40; 95%CI: 0.92-2.11; p=0.113) or in-hospital (OR: 1.23; 95%CI: 0.85-1.75; p=0.265) mortality. Conclusion: Intensive care unit admission during medical handover did not affect in-hospital mortality in this propensity-matched, single-center cohort study.
MeSH term(s)	Adult ; Cohort Studies ; Hospital Mortality ; Humans ; Intensive Care Units ; Patient Handoff ; Retrospective Studies
Language	Portuguese
Publishing date	2021-06-18
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2418293-X
ISSN	2317-6385 ; 1679-4508
ISSN (online)	2317-6385
ISSN	1679-4508
DOI	10.31744/einstein_journal/2021AO5748
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