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  1. Article ; Online: Letter to the Editor regarding Çelik et al: "Oral corticosteroids vs. exercises on treatment of frozen shoulder: a randomized, single-blinded study".

    Sinha, Pratik

    Journal of shoulder and elbow surgery

    2023  Volume 32, Issue 11, Page(s) e583

    MeSH term(s) Humans ; Exercise Therapy ; Bursitis/drug therapy ; Exercise ; Single-Blind Method ; Adrenal Cortex Hormones/therapeutic use
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2023-08-07
    Publishing country United States
    Document type Randomized Controlled Trial ; Letter
    ZDB-ID 1170782-3
    ISSN 1532-6500 ; 1058-2746
    ISSN (online) 1532-6500
    ISSN 1058-2746
    DOI 10.1016/j.jse.2023.06.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Are There Distinct Cardiovascular Subclasses in Acute Respiratory Distress Syndrome? Maybe.

    Sinha, Pratik / Lawler, Patrick R

    Critical care medicine

    2023  Volume 51, Issue 4, Page(s) 546–549

    MeSH term(s) Humans ; Lung ; Respiratory Distress Syndrome/therapy ; Heart
    Language English
    Publishing date 2023-03-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000005816
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Cutting the Gordian knot of heterogeneity: Can integrated systems biology modelling rescue critical care syndromes?

    Maddali, Manoj V / Sinha, Pratik

    EBioMedicine

    2022  Volume 77, Page(s) 103884

    MeSH term(s) Critical Care ; Humans ; Syndrome ; Systems Biology
    Language English
    Publishing date 2022-02-14
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2851331-9
    ISSN 2352-3964
    ISSN (online) 2352-3964
    DOI 10.1016/j.ebiom.2022.103884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Cutting the Gordian knot of heterogeneity

    Manoj V. Maddali / Pratik Sinha

    EBioMedicine, Vol 77, Iss , Pp 103884- (2022)

    Can integrated systems biology modelling rescue critical care syndromes?

    2022  

    Keywords Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Genome-wide association studies in ARDS: SNPing the tangled web of heterogeneity.

    Clohisey, Sara / Sinha, Pratik

    Intensive care medicine

    2021  Volume 47, Issue 7, Page(s) 782–785

    MeSH term(s) Genome-Wide Association Study ; Humans ; Respiratory Distress Syndrome/genetics
    Language English
    Publishing date 2021-06-26
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-021-06462-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Immunotherapy in COVID-19: why, who, and when?

    Sinha, Pratik / Calfee, Carolyn S

    The Lancet. Respiratory medicine

    2021  Volume 9, Issue 6, Page(s) 549–551

    MeSH term(s) COVID-19 ; Humans ; Immunologic Factors ; Immunotherapy ; Receptors, Interleukin-6 ; SARS-CoV-2
    Chemical Substances Immunologic Factors ; Receptors, Interleukin-6
    Language English
    Publishing date 2021-05-18
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S. ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(21)00232-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Contact tracing: Can 'Big tech' come to the rescue, and if so, at what cost?

    Sinha, Pratik / Paterson, Alastair E

    EClinicalMedicine

    2020  Volume 24, Page(s) 100412

    Keywords covid19
    Language English
    Publishing date 2020-06-15
    Publishing country England
    Document type Journal Article
    ISSN 2589-5370
    ISSN (online) 2589-5370
    DOI 10.1016/j.eclinm.2020.100412
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Pathophysiology of the Acute Respiratory Distress Syndrome: Insights from Clinical Studies.

    Sinha, Pratik / Bos, Lieuwe D

    Critical care clinics

    2021  Volume 37, Issue 4, Page(s) 795–815

    Abstract: Acute respiratory distress syndrome (ARDS) is a heterogeneous clinical syndrome that manifests secondary to numerous etiologic insults, and consequently it is associated with a multitude of pathophysiological abnormalities. Despite more than 50 years of ... ...

    Abstract Acute respiratory distress syndrome (ARDS) is a heterogeneous clinical syndrome that manifests secondary to numerous etiologic insults, and consequently it is associated with a multitude of pathophysiological abnormalities. Despite more than 50 years of experimental studies, translation of these benchside discoveries into effective biological therapies has been elusive. In this review, some of the key advances made in our knowledge of the pathophysiology of ARDS, based on histopathology, imaging, protein, and transcriptomic biomarkers, are presented. Finally, the role of such human studies in understanding the pathophysiology of coronavirus disease 2019-related ARDS is reviewed.
    MeSH term(s) Biomarkers ; COVID-19 ; Humans ; Respiratory Distress Syndrome/etiology ; Respiratory Distress Syndrome/therapy ; SARS-CoV-2
    Chemical Substances Biomarkers
    Language English
    Publishing date 2021-05-26
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1006423-0
    ISSN 1557-8232 ; 0749-0704
    ISSN (online) 1557-8232
    ISSN 0749-0704
    DOI 10.1016/j.ccc.2021.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Contact tracing

    Pratik Sinha / Alastair E Paterson

    EClinicalMedicine, Vol 24, Iss , Pp 100412- (2020)

    Can ‘Big tech’ come to the rescue, and if so, at what cost?

    2020  

    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Biological Phenotyping in Sepsis and Acute Respiratory Distress Syndrome.

    Sinha, Pratik / Meyer, Nuala J / Calfee, Carolyn S

    Annual review of medicine

    2022  Volume 74, Page(s) 457–471

    Abstract: Heterogeneity in sepsis and acute respiratory distress syndrome (ARDS) is increasingly being recognized as one of the principal barriers to finding efficacious targeted therapies. The advent of multiple high-throughput biological data ("omics"), coupled ... ...

    Abstract Heterogeneity in sepsis and acute respiratory distress syndrome (ARDS) is increasingly being recognized as one of the principal barriers to finding efficacious targeted therapies. The advent of multiple high-throughput biological data ("omics"), coupled with the widespread access to increased computational power, has led to the emergence of phenotyping in critical care. Phenotyping aims to use a multitude of data to identify homogenous subgroups within an otherwise heterogenous population. Increasingly, phenotyping schemas are being applied to sepsis and ARDS to increase understanding of these clinical conditions and identify potential therapies. Here we present a selective review of the biological phenotyping schemas applied to sepsis and ARDS. Further, we outline some of the challenges involved in translating these conceptual findings to bedside clinical decision-making tools.
    MeSH term(s) Humans ; Respiratory Distress Syndrome/therapy ; Sepsis
    Language English
    Publishing date 2022-12-05
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
    ZDB-ID 207930-6
    ISSN 1545-326X ; 0066-4219
    ISSN (online) 1545-326X
    ISSN 0066-4219
    DOI 10.1146/annurev-med-043021-014005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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