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  1. Book ; Online: Temperature and salinity profiles at 10 m depth resolution from time series station E1 in the western English Channel from 1903 to 2010, supplementary data to: Smyth, Timothy J; Fishwick, James R; Al-Moosawi, Lisa; Cummings, Denise G; Harris, Carolyn; Kitidis, Vasillis; Rees, Andrew; Martinez-Vicente, Victor; Woodward, E Malcolm S (2010): A broad spatio-temporal view of the Western English Channel observatory. Journal of Plankton Research, 32(5), 585-601

    Smyth, Timothy J / Al-Moosawi, Lisa / Cummings, Denise G / Fishwick, James R / Harris, Carolyn / Kitidis, Vasillis / Martinez-Vicente, Victor / Rees, Andrew / Woodward, E Malcolm S

    2010  

    Abstract: The marine laboratories in Plymouth have sampled at two principle sites in the Western English Channel for over a century in open-shelf (station E1; 50? 02'N, 4? 22'W) and coastal (station L4; 50? 15'N, 4? 13'W) waters. These stations are seasonally ... ...

    Abstract The marine laboratories in Plymouth have sampled at two principle sites in the Western English Channel for over a century in open-shelf (station E1; 50? 02'N, 4? 22'W) and coastal (station L4; 50? 15'N, 4? 13'W) waters. These stations are seasonally stratified from late-April until September, and the variable biological response is regulated by subtle variations in temperature, light, nutrients and meteorology. Station L4 is characterized by summer nutrient depletion, although intense summer precipitation, increasing riverine input to the system, results in pulses of increased nitrate concentration and surface freshening. The winter nutrient concentrations at E1 are consistent with an open-shelf site. Both stations have a spring and autumn phytoplankton bloom; at station E1, the autumn bloom tends to dominate in terms of chlorophyll concentration. The last two decades have seen a warming of around 0.6?C per decade, and this is superimposed on several periods of warming and cooling over the past century. In general, over the Western English Channel domain, the end of the 20th century was around 0.5?C warmer than the first half of the century. The warming magnitude and trend is consistent with other stations across the north-west European Shelf and occurred during a period of reduced wind stress and increased levels of insolation (+20%); these are both correlated with the larger scale climatic forcing of the North Atlantic Oscillation.
    Language English
    Dates of publication 2010-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1093/plankt/fbp128
    DOI 10.1594/PANGAEA.742659
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  2. Article ; Online: Editorial

    Andrew P. Rees / Timothy J. Smyth / Vanda Brotas

    Frontiers in Marine Science, Vol

    The Atlantic Meridional Transect programme (1995-2023)

    2024  Volume 11

    Keywords AMT ; Atlantic Meridional Transect ; sustained observations ; biodiversity ; biogeochemistry ; environmental change ; Science ; Q ; General. Including nature conservation ; geographical distribution ; QH1-199.5
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Distinct proliferative and middle ear skeletal-patterning functions for SHH-expressing epithelia in the chick hyoid arch.

    Rees, Jenaid M / Gillis, J Andrew

    Developmental biology

    2022  Volume 489, Page(s) 98–108

    Abstract: During chick craniofacial development, the second (hyoid) pharyngeal arch expands to close the neck and gives rise to skeletal elements, including the columella of the middle ear (a homologue of the mammalian stapes). Sonic hedgehog (SHH) signalling has ... ...

    Abstract During chick craniofacial development, the second (hyoid) pharyngeal arch expands to close the neck and gives rise to skeletal elements, including the columella of the middle ear (a homologue of the mammalian stapes). Sonic hedgehog (SHH) signalling has been implicated in hyoid arch expansion and columella formation, but spatial and temporal aspects of these signalling interactions within the hyoid arch remain poorly understood. Here, we show that SHH is initially expressed in the posterior endoderm of the hyoid arch, and that this domain subsequently splits into a distal domain at the site of arch expansion (the posterior epithelial margin, PEM), and a proximal domain that lines the foregut (the proximal hyoid epithelium, PHE). Pharmacological manipulations and heterotopic grafting experiments demonstrate that SHH signalling is required for hyoid arch expansion and skeletogenesis, and reveal distinct roles for the PEM and PHE in these processes. The PEM promotes mesenchymal cell proliferation during arch expansion but is not sufficient to repattern the columella. Conversely, the PHE promotes mesenchymal cell survival, and PHE grafts induce partial duplication of the columella. This work demonstrates crucial and distinct roles for endodermal SHH signalling in hyoid arch morphogenesis and patterning of the middle ear skeleton.
    MeSH term(s) Animals ; Body Patterning ; Branchial Region/metabolism ; Ear, Middle ; Endoderm/metabolism ; Epithelium/metabolism ; Gene Expression Regulation, Developmental ; Hedgehog Proteins/metabolism ; Mammals/metabolism
    Chemical Substances Hedgehog Proteins
    Language English
    Publishing date 2022-06-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1114-9
    ISSN 1095-564X ; 0012-1606
    ISSN (online) 1095-564X
    ISSN 0012-1606
    DOI 10.1016/j.ydbio.2022.06.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Case Report-Traumatic L5-S1 Instability: Are Upright Radiographs Potentially Dangerous?

    Rees, Andrew B / Croft, Andrew J / Varas-Rodrguez, Emil / Stephens, Byron F / Abtahi, Amir M

    International journal of spine surgery

    2023  Volume 17, Issue 2, Page(s) 324–332

    Language English
    Publishing date 2023-04-13
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2211-4599
    ISSN 2211-4599
    DOI 10.14444/8432
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Fgf signalling is required for gill slit formation in the skate, Leucoraja erinacea.

    Rees, Jenaid M / Palmer, Michael A / Gillis, J Andrew

    Developmental biology

    2023  Volume 506, Page(s) 85–94

    Abstract: The gill slits of fishes develop from an iterative series of pharyngeal endodermal pouches that contact and fuse with surface ectoderm on either side of the embryonic head. We find in the skate (Leucoraja erinacea) that all gill slits form via a ... ...

    Abstract The gill slits of fishes develop from an iterative series of pharyngeal endodermal pouches that contact and fuse with surface ectoderm on either side of the embryonic head. We find in the skate (Leucoraja erinacea) that all gill slits form via a stereotypical sequence of epithelial interactions: 1) endodermal pouches approach overlying surface ectoderm, with 2) focal degradation of ectodermal basement membranes preceding endoderm-ectoderm contact; 3) endodermal pouches contact and intercalate with overlying surface ectoderm, and finally 4) perforation of a gill slit occurs by epithelial remodelling, without programmed cell death, at the site of endoderm-ectoderm intercalation. Skate embryos express Fgf8 and Fgf3 within developing pharyngeal epithelia during gill slit formation. When we inhibit Fgf signalling by treating skate embryos with the Fgf receptor inhibitor SU5402 we find that endodermal pouch formation, basement membrane degradation and endodermal-ectodermal intercalation are unaffected, but that epithelial remodelling and gill slit perforation fail to occur. These findings point to a role for Fgf signalling in epithelial remodelling during gill slit formation in the skate and, more broadly, to an ancestral role for Fgf signalling during pharyngeal pouch epithelial morphogenesis in vertebrate embryos.
    MeSH term(s) Animals ; Gills ; Ectoderm ; Endoderm ; Vertebrates ; Morphogenesis
    Language English
    Publishing date 2023-11-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1114-9
    ISSN 1095-564X ; 0012-1606
    ISSN (online) 1095-564X
    ISSN 0012-1606
    DOI 10.1016/j.ydbio.2023.11.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Ectodermal Wnt signaling, cell fate determination, and polarity of the skate gill arch skeleton.

    Rees, Jenaid M / Sleight, Victoria A / Clark, Stephen J / Nakamura, Tetsuya / Gillis, J Andrew

    eLife

    2023  Volume 12

    Abstract: The gill skeleton of cartilaginous fishes (sharks, skates, rays, and holocephalans) exhibits a striking anterior-posterior polarity, with a series of fine appendages called branchial rays projecting from the posterior margin of the gill arch cartilages. ... ...

    Abstract The gill skeleton of cartilaginous fishes (sharks, skates, rays, and holocephalans) exhibits a striking anterior-posterior polarity, with a series of fine appendages called branchial rays projecting from the posterior margin of the gill arch cartilages. We previously demonstrated in the skate (
    MeSH term(s) Animals ; Branchial Region ; Wnt Signaling Pathway ; Hedgehog Proteins/genetics ; Ectoderm ; Gills ; Skates, Fish ; Skeleton
    Chemical Substances Hedgehog Proteins
    Language English
    Publishing date 2023-03-20
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.79964
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  7. Article: Distinct proliferative and middle ear skeletal-patterning functions for SHH-expressing epithelia in the chick hyoid arch

    Rees, Jenaid M. / Gillis, J. Andrew

    Developmental biology. 2022 Sept., v. 489

    2022  

    Abstract: During chick craniofacial development, the second (hyoid) pharyngeal arch expands to close the neck and gives rise to skeletal elements, including the columella of the middle ear (a homologue of the mammalian stapes). Sonic hedgehog (SHH) signalling has ... ...

    Abstract During chick craniofacial development, the second (hyoid) pharyngeal arch expands to close the neck and gives rise to skeletal elements, including the columella of the middle ear (a homologue of the mammalian stapes). Sonic hedgehog (SHH) signalling has been implicated in hyoid arch expansion and columella formation, but spatial and temporal aspects of these signalling interactions within the hyoid arch remain poorly understood. Here, we show that SHH is initially expressed in the posterior endoderm of the hyoid arch, and that this domain subsequently splits into a distal domain at the site of arch expansion (the posterior epithelial margin, PEM), and a proximal domain that lines the foregut (the proximal hyoid epithelium, PHE). Pharmacological manipulations and heterotopic grafting experiments demonstrate that SHH signalling is required for hyoid arch expansion and skeletogenesis, and reveal distinct roles for the PEM and PHE in these processes. The PEM promotes mesenchymal cell proliferation during arch expansion but is not sufficient to repattern the columella. Conversely, the PHE promotes mesenchymal cell survival, and PHE grafts induce partial duplication of the columella. This work demonstrates crucial and distinct roles for endodermal SHH signalling in hyoid arch morphogenesis and patterning of the middle ear skeleton.
    Keywords cell proliferation ; cell viability ; chicks ; endoderm ; epithelium ; foregut ; mammals ; middle ear ; morphogenesis ; neck ; pharynx ; skeleton
    Language English
    Dates of publication 2022-09
    Size p. 98-108.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 1114-9
    ISSN 1095-564X ; 0012-1606
    ISSN (online) 1095-564X
    ISSN 0012-1606
    DOI 10.1016/j.ydbio.2022.06.004
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Decoupling of omicron variant infections and severe COVID-19.

    Madhi, Shabir A / Ihekweazu, Chikwe / Rees, Helen / Pollard, Andrew J

    Lancet (London, England)

    2022  Volume 399, Issue 10329, Page(s) 1047–1048

    MeSH term(s) COVID-19/prevention & control ; COVID-19 Vaccines/immunology ; Humans ; Patient Acuity ; SARS-CoV-2/immunology ; Vaccine Efficacy
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-02-18
    Publishing country England
    Document type Letter
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(22)00109-X
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  9. Article ; Online: The Starfish Procedure for Independent Digital Control of a Myoelectric Prosthesis.

    Denduluri, Sahitya K / Rees, Andrew / Nord, Keith M / Loeffler, Bryan J / Gaston, R Glenn

    Techniques in hand & upper extremity surgery

    2023  Volume 27, Issue 1, Page(s) 61–67

    Abstract: Management of partial hand amputations is a notable clinical challenge. Historically, myoelectric prostheses have not allowed for independent digital control, resulting in unsatisfactory function and high rejection rates among upper extremity amputees. ... ...

    Abstract Management of partial hand amputations is a notable clinical challenge. Historically, myoelectric prostheses have not allowed for independent digital control, resulting in unsatisfactory function and high rejection rates among upper extremity amputees. The Starfish Procedure was developed for patients who sustained loss of multiple digits through the level of the base of the proximal phalanx or distal metacarpal. The procedure involves the pedicled transfer of 1 or more dorsal interosseous muscles to a subcutaneous location. This allows for a myoelectric sensor to capture the signals generated by these transferred muscles, thereby enabling intuitive, independent, digital prosthetic flexion and extension. In this article, we detail the relevant anatomy, indications, and technique for performing the Starfish Procedure. Given our patients' promising outcomes to date, we hope this technique paper will encourage upper extremity surgeons of all training backgrounds to perform this relatively straightforward procedure, thereby allowing patients with life-altering finger amputations to regain meaningful function by enhancing control of digital prostheses.
    MeSH term(s) Humans ; Prosthesis Design ; Artificial Limbs ; Hand ; Fingers/surgery ; Upper Extremity
    Language English
    Publishing date 2023-03-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2075789-X
    ISSN 1531-6572 ; 1089-3393
    ISSN (online) 1531-6572
    ISSN 1089-3393
    DOI 10.1097/BTH.0000000000000412
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  10. Article: Purulent pneumococcal pericarditis, a vaccine-preventable illness.

    Rees, Matthew J / Wilson, Andrew

    Oxford medical case reports

    2019  Volume 2019, Issue 8, Page(s) omz078

    Abstract: A 74-year-old gentleman presented to hospital with a 1-day history of acute onset pleuritic chest pain and fever. He was found to have widespread ST segment elevation on electrocardiogram, and blood cultures taken were positive ... ...

    Abstract A 74-year-old gentleman presented to hospital with a 1-day history of acute onset pleuritic chest pain and fever. He was found to have widespread ST segment elevation on electrocardiogram, and blood cultures taken were positive for
    Language English
    Publishing date 2019-08-29
    Publishing country England
    Document type Case Reports
    ZDB-ID 2766251-2
    ISSN 2053-8855
    ISSN 2053-8855
    DOI 10.1093/omcr/omz078
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