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  1. Article ; Online: SMAD4 gene mutation and risk of aortic dilation: Lessons from hereditary hemorrhagic telangiectasia.

    Cavalli, Giulio

    International journal of cardiology

    2017  Volume 245, Page(s) 145–146

    Language English
    Publishing date 2017-10-15
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2017.07.046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1673: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  2. Article ; Online: The course of action for effective anti-cytokine treatment in COVID-19.

    Cavalli, Giulio / Dagna, Lorenzo

    The Lancet. Respiratory medicine

    2021  Volume 9, Issue 12, Page(s) 1353–1354

    MeSH term(s) COVID-19 ; Cytokines ; Humans ; SARS-CoV-2 ; Treatment Outcome
    Chemical Substances Cytokines
    Language English
    Publishing date 2021-10-29
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(21)00405-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7041: Show issues Location:
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  3. Article ; Online: The right place for IL-1 inhibition in COVID-19.

    Cavalli, Giulio / Dagna, Lorenzo

    The Lancet. Respiratory medicine

    2021  Volume 9, Issue 3, Page(s) 223–224

    MeSH term(s) Adult ; COVID-19 ; Hospitals ; Humans ; Interleukin 1 Receptor Antagonist Protein ; Interleukin-1 ; Pneumonia ; SARS-CoV-2
    Chemical Substances Interleukin 1 Receptor Antagonist Protein ; Interleukin-1
    Language English
    Publishing date 2021-01-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(21)00035-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7041: Show issues Location:
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  4. Article ; Online: Biologic discontinuation strategies and outcomes in patients with rheumatoid arthritis.

    Cavalli, Giulio / Favalli, Ennio Giulio

    Expert review of clinical immunology

    2019  Volume 15, Issue 12, Page(s) 1313–1322

    Abstract: ... ...

    Abstract Introduction
    MeSH term(s) Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/drug therapy ; Arthritis, Rheumatoid/immunology ; Arthritis, Rheumatoid/pathology ; Biological Products/therapeutic use ; Humans ; Observational Studies as Topic ; Randomized Controlled Trials as Topic ; Remission Induction
    Chemical Substances Antirheumatic Agents ; Biological Products
    Language English
    Publishing date 2019-11-10
    Publishing country England
    Document type Journal Article ; Review ; Video-Audio Media
    ZDB-ID 2274260-8
    ISSN 1744-8409 ; 1744-666X
    ISSN (online) 1744-8409
    ISSN 1744-666X
    DOI 10.1080/1744666X.2020.1686976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6661: Show issues Location:
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  5. Article ; Online: Anakinra in COVID-19-How to Interpret Elevations of Serum Liver Enzymes: Comment on the Article by Navarro-Millán et al.

    Cavalli, Giulio / Dagna, Lorenzo

    Arthritis & rheumatology (Hoboken, N.J.)

    2021  Volume 73, Issue 3, Page(s) 549

    MeSH term(s) COVID-19 ; Humans ; Interleukin 1 Receptor Antagonist Protein ; Liver ; Respiration, Artificial ; SARS-CoV-2
    Chemical Substances Interleukin 1 Receptor Antagonist Protein
    Keywords covid19
    Language English
    Publishing date 2021-01-29
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2756371-6
    ISSN 2326-5205 ; 2326-5191
    ISSN (online) 2326-5205
    ISSN 2326-5191
    DOI 10.1002/art.41525
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    Zs.A 24: Show issues Location:
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  6. Article ; Online: Effect of anakinra in COVID-19 - Authors' reply.

    Cavalli, Giulio / Dagna, Lorenzo

    The Lancet Rheumatology

    2020  Volume 2, Issue 9, Page(s) e524–e525

    Keywords covid19
    Language English
    Publishing date 2020-07-24
    Publishing country England
    Document type Journal Article
    ISSN 2665-9913
    ISSN (online) 2665-9913
    DOI 10.1016/S2665-9913(20)30236-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Large-scale use of hydroxychloroquine for COVID-19 confirms safety, if not effectiveness.

    Cavalli, Giulio / Dagna, Lorenzo

    European journal of internal medicine

    2020  Volume 82, Page(s) 23–24

    MeSH term(s) Antiviral Agents/therapeutic use ; COVID-19 ; Humans ; Hydroxychloroquine/adverse effects ; Italy ; SARS-CoV-2
    Chemical Substances Antiviral Agents ; Hydroxychloroquine (4QWG6N8QKH)
    Keywords covid19
    Language English
    Publishing date 2020-10-28
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2020.10.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2608: Show issues Location:
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  8. Article: Cardiovascular disease in patients with rheumatoid arthritis: impact of classic and disease-specific risk factors.

    Cavalli, Giulio / Favalli, Ennio Giulio

    Annals of translational medicine

    2017  Volume 6, Issue Suppl 1, Page(s) S82

    Language English
    Publishing date 2017-11-21
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2893931-1
    ISSN 2305-5847 ; 2305-5839
    ISSN (online) 2305-5847
    ISSN 2305-5839
    DOI 10.21037/atm.2018.10.72
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Interleukin-1 and interleukin-6 inhibition in patients with COVID-19 and hyperinflammation - Authors' reply.

    Cavalli, Giulio / Larcher, Alessandro / Tomelleri, Alessandro / Dagna, Lorenzo

    The Lancet. Rheumatology

    2021  Volume 3, Issue 4, Page(s) e248–e249

    Language English
    Publishing date 2021-03-08
    Publishing country England
    Document type Journal Article
    ISSN 2665-9913
    ISSN (online) 2665-9913
    DOI 10.1016/S2665-9913(21)00066-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Autophagy and Protein Secretion.

    Cavalli, Giulio / Cenci, Simone

    Journal of molecular biology

    2020  Volume 432, Issue 8, Page(s) 2525–2545

    Abstract: Autophagy - conventional for macroautophagy - is a major recycling strategy that ensures cellular homeostasis through the selective engulfment of cytoplasmic supramolecular cargos in double membrane vesicles and their rapid dispatch to the lysosome for ... ...

    Abstract Autophagy - conventional for macroautophagy - is a major recycling strategy that ensures cellular homeostasis through the selective engulfment of cytoplasmic supramolecular cargos in double membrane vesicles and their rapid dispatch to the lysosome for digestion. As autophagy operates in the cytoplasm, its interference with secretory proteins, that is, proteins destined to the plasma membrane or the extracellular space, generally synthesized and routed within the endoplasmic reticulum (ER), has been relatively overlooked in the past. However, mounting evidence reveals that autophagy in fact heavily regulates protein secretion through diverse mechanisms. First, autophagy is closely involved in the unconventional secretion of leaderless proteins, a pool of proteins destined extracellularly, but lacking an ER-targeted leader sequence, and thus manufactured in the cytosol. Autophagy-related (ATG) genes now appear instrumental to the underlying pathways, hence the recently coined concept of secretory autophagy, or better ATG gene-dependent secretion. Indeed, ATG genes regulate unconventional protein secretion at multiple levels, ranging from intracellular inflammatory signaling, for example, through the control of mitochondrial health and inflammasome activity, to trafficking of leaderless proteins. Moreover, perhaps less expectedly, autophagy also participates in the control of conventional secretion, intersecting the secretory apparatus at multiple points, though with surprising differences among professional secretory cell types that disclose remarkable and unpredicted specificity. This review synopsizes the multiple mechanisms whereby autophagy interfaces with conventional and unconventional protein secretory pathways and discusses the relative teleology. Altogether, the diverse controls exerted on protein secretion broaden and deepen the homeostatic significance of autophagy within the cell.
    MeSH term(s) Animals ; Autophagy ; Cell Membrane/metabolism ; Endoplasmic Reticulum/metabolism ; Humans ; Lysosomes/metabolism ; Neurodegenerative Diseases/metabolism ; Neurodegenerative Diseases/pathology ; Protein Transport ; Proteins/metabolism ; Secretory Pathway ; Signal Transduction
    Chemical Substances Proteins
    Language English
    Publishing date 2020-01-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 80229-3
    ISSN 1089-8638 ; 0022-2836
    ISSN (online) 1089-8638
    ISSN 0022-2836
    DOI 10.1016/j.jmb.2020.01.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 867: Show issues Location:
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