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  1. Article ; Online: More evidences on which biologic and which pathway is key in severe-critical COVID-19 pneumonia.

    Ferraccioli, Gianfranco

    Annals of the rheumatic diseases

    2020  

    Keywords covid19
    Language English
    Publishing date 2020-07-31
    Publishing country England
    Document type Letter
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/annrheumdis-2020-218523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Difficult to treat rheumatoid arthritis: Sequential therapy with different personalized biological targets could be an option.

    Gremese, Elisa / Bruno, Dario / Nagy, György / Ferraccioli, Gianfranco

    European journal of internal medicine

    2024  

    Language English
    Publishing date 2024-01-31
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2024.01.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Severe hand deformities in an undertreated condition.

    Gremese, Elisa / Bruno, Dario / Ferraccioli, Gianfranco

    European journal of internal medicine

    2023  Volume 119, Page(s) 125–126

    MeSH term(s) Humans ; Hand Deformities ; Arthritis, Rheumatoid ; Hand
    Language English
    Publishing date 2023-10-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1038679-8
    ISSN 1879-0828 ; 0953-6205
    ISSN (online) 1879-0828
    ISSN 0953-6205
    DOI 10.1016/j.ejim.2023.09.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: More evidences on which biologic and which pathway is key in severe-critical COVID-19 pneumonia

    Ferraccioli, Gianfranco

    Annals of the Rheumatic Diseases

    2020  , Page(s) annrheumdis–2020–218523

    Keywords Immunology ; General Biochemistry, Genetics and Molecular Biology ; Immunology and Allergy ; Rheumatology ; covid19
    Language English
    Publisher BMJ
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/annrheumdis-2020-218523
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Case report: crowned dens syndrome in a patient with seronegative rheumatoid arthritis.

    Ferraccioli, Gianfranco / Zanardi, Romeo / Gremese, Elisa

    RMD open

    2023  Volume 9, Issue 2

    Abstract: Chondrocalcinosis (CC) is the one of the most common crystal pyrophosphate disease associated arthritis in the elderly. It has been shown to coexist with seronegative and seropositive rheumatoid arthritis (RA), yet mostly with seronegative RA. Among the ... ...

    Abstract Chondrocalcinosis (CC) is the one of the most common crystal pyrophosphate disease associated arthritis in the elderly. It has been shown to coexist with seronegative and seropositive rheumatoid arthritis (RA), yet mostly with seronegative RA. Among the localisation of CC, the deposition in the ligaments surrounding the odontoid process may remain asymptomatic for years or may lead to and acute severe symptomatology, which may mimic several clinical illnesses among which meningitis (fever, severe pain, acute phase reactants). This is called the 'crowned dens syndrome (CDS)', which has been reported to represent an important percentage of acute neck pain needing hospital admission in neurosurgery units. In this case, the rapid demonstration of 'crowned dens' through CT scan may allow to avoid lumbar puncture and cerebrospinal fluid examination. The coexistence of RA and CDS is very rare, and rarely reported in the literature, yet it may represent a clinical challenge. We describe here one case that while on therapy with methotrexate (MTX) and naproxen (NPX) had an acute neck pain, and peripheral arthritis flare, that responded well to colchicine given along with MTX and NPX.
    MeSH term(s) Humans ; Aged ; Neck Pain/etiology ; Neck Pain/complications ; Chondrocalcinosis/complications ; Chondrocalcinosis/diagnosis ; Chondrocalcinosis/drug therapy ; Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/diagnosis ; Arthritis, Rheumatoid/drug therapy ; Syndrome ; Colchicine ; Naproxen ; Methotrexate/therapeutic use
    Chemical Substances Colchicine (SML2Y3J35T) ; Naproxen (57Y76R9ATQ) ; Methotrexate (YL5FZ2Y5U1)
    Language English
    Publishing date 2023-04-03
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2812592-7
    ISSN 2056-5933 ; 2056-5933
    ISSN (online) 2056-5933
    ISSN 2056-5933
    DOI 10.1136/rmdopen-2023-003017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Correspondence on "Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: results from the COVID-19 Global Rheumatology Alliance physician registry" by Sparks

    Gremese, Elisa / Ferraccioli, Gianfranco

    Annals of the rheumatic diseases

    2021  Volume 82, Issue 7, Page(s) e157

    MeSH term(s) Humans ; Rheumatology ; COVID-19 ; Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/drug therapy ; Biological Products/therapeutic use ; Registries
    Chemical Substances Antirheumatic Agents ; Biological Products
    Language English
    Publishing date 2021-08-23
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/annrheumdis-2021-220932
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Case report

    Gianfranco Ferraccioli / Elisa Gremese / Romeo Zanardi

    RMD Open, Vol 9, Iss

    crowned dens syndrome in a patient with seronegative rheumatoid arthritis

    2023  Volume 2

    Abstract: Chondrocalcinosis (CC) is the one of the most common crystal pyrophosphate disease associated arthritis in the elderly. It has been shown to coexist with seronegative and seropositive rheumatoid arthritis (RA), yet mostly with seronegative RA. Among the ... ...

    Abstract Chondrocalcinosis (CC) is the one of the most common crystal pyrophosphate disease associated arthritis in the elderly. It has been shown to coexist with seronegative and seropositive rheumatoid arthritis (RA), yet mostly with seronegative RA. Among the localisation of CC, the deposition in the ligaments surrounding the odontoid process may remain asymptomatic for years or may lead to and acute severe symptomatology, which may mimic several clinical illnesses among which meningitis (fever, severe pain, acute phase reactants). This is called the ‘crowned dens syndrome (CDS)’, which has been reported to represent an important percentage of acute neck pain needing hospital admission in neurosurgery units. In this case, the rapid demonstration of ‘crowned dens’ through CT scan may allow to avoid lumbar puncture and cerebrospinal fluid examination. The coexistence of RA and CDS is very rare, and rarely reported in the literature, yet it may represent a clinical challenge. We describe here one case that while on therapy with methotrexate (MTX) and naproxen (NPX) had an acute neck pain, and peripheral arthritis flare, that responded well to colchicine given along with MTX and NPX.
    Keywords Medicine ; R
    Subject code 610
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Morbidity and Mortality From COVID-19 Are Not Increased Among Children or Patients With Autoimmune Rheumatic Disease-Possible Immunologic Rationale: Comment on the Article by Henderson et al.

    Ferraccioli, Edoardo Sean / Gremese, Elisa / Ferraccioli, Gianfranco

    Arthritis & rheumatology (Hoboken, N.J.)

    2020  Volume 72, Issue 10, Page(s) 1772–1774

    MeSH term(s) COVID-19 ; Child ; Cytokine Release Syndrome ; Humans ; Morbidity ; Pandemics ; Rheumatic Diseases/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2756371-6
    ISSN 2326-5205 ; 2326-5191
    ISSN (online) 2326-5205
    ISSN 2326-5191
    DOI 10.1002/art.41399
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  9. Article: The forgotten key players in rheumatoid arthritis: IL-8 and IL-17 - Unmet needs and therapeutic perspectives.

    Gremese, Elisa / Tolusso, Barbara / Bruno, Dario / Perniola, Simone / Ferraccioli, Gianfranco / Alivernini, Stefano

    Frontiers in medicine

    2023  Volume 10, Page(s) 956127

    Abstract: Despite the relevant advances in our understanding of the pathogenetic mechanisms regulating inflammation in rheumatoid arthritis (RA) and the development of effective therapeutics, to date, there is still a proportion of patients with RA who do not ... ...

    Abstract Despite the relevant advances in our understanding of the pathogenetic mechanisms regulating inflammation in rheumatoid arthritis (RA) and the development of effective therapeutics, to date, there is still a proportion of patients with RA who do not respond to treatment and end up progressing toward the development of joint damage, extra-articular complications, and disability. This is mainly due to the inter-individual heterogeneity of the molecular and cellular taxonomy of the synovial membrane, which represents the target tissue of RA inflammation. Tumor necrosis factor alpha (TNFα) and interleukin-6 (IL-6) are crucial key players in RA pathogenesis fueling the inflammatory cascade, as supported by experimental evidence derived from
    Language English
    Publishing date 2023-03-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.956127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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