Result 1 - 10 of total 979
Western journal of medicine and surgery
2024 Volume 4, Issue 5, Page(s) 398
| Language | English |
|---|---|
| Publishing date | 2024-01-11 |
| Publishing country | United States |
| Document type | Journal Article |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
The Medical journal of Australia
2023 Volume 220, Issue 2, Page(s) 64–66
| MeSH term(s) | Humans ; Urban Health ; Health Services Accessibility ; Healthcare Disparities ; Australia |
|---|---|
| Language | English |
| Publishing date | 2023-11-29 |
| Publishing country | Australia |
| Document type | Journal Article ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 186082-3 |
| ISSN | 1326-5377 ; 0025-729X |
| ISSN (online) | 1326-5377 |
| ISSN | 0025-729X |
| DOI | 10.5694/mja2.52181 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Ua VI Zs.398: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
American journal of physiology. Cell physiology
2022 Volume 323, Issue 2, Page(s) C378–C384
Abstract: Skeletal muscle atrophy and dysfunction contribute to morbidity and mortality in patients with cancer. Cachexia pathophysiology is highly complex, given that perturbations to the systemic cancer environment and the interaction with diverse tissues can ... ...
| Abstract | Skeletal muscle atrophy and dysfunction contribute to morbidity and mortality in patients with cancer. Cachexia pathophysiology is highly complex, given that perturbations to the systemic cancer environment and the interaction with diverse tissues can contribute to wasting processes. Systemic interleukin 6 (IL-6) and glycoprotein 130 (gp130) receptors signaling have established roles in some types of cancer-induced muscle wasting through disruptions to protein turnover and oxidative capacity. Although exercise has documented benefits for cancer prevention and patient survival, there are significant gaps in our understanding of muscle adaptation and plasticity during severe cachexia. Preclinical models have provided valuable insight into the adaptive potential of muscle contraction within the cancer environment. We summarize the current understanding of how resistance-type exercise impacts mechanisms involved in cancer-induced muscle atrophy and dysfunction. Specifically, the role of IL-6 and gp130 receptors in the pathophysiology of muscle wasting and the adaptive response to exercise is explained. The discussion includes current knowledge gaps and future research directions needed to improve preclinical research and accelerate clinical translation in human patients with cancer. |
|---|---|
| MeSH term(s) | Cachexia/etiology ; Cachexia/prevention & control ; Cytokine Receptor gp130/metabolism ; Humans ; Interleukin-6/metabolism ; Muscle Contraction ; Muscle, Skeletal/metabolism ; Muscular Atrophy/pathology ; Neoplasms/metabolism |
| Chemical Substances | Interleukin-6 ; Cytokine Receptor gp130 (133483-10-0) |
| Language | English |
| Publishing date | 2022-06-15 |
| Publishing country | United States |
| Document type | Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 392098-7 |
| ISSN | 1522-1563 ; 0363-6143 |
| ISSN (online) | 1522-1563 |
| ISSN | 0363-6143 |
| DOI | 10.1152/ajpcell.00021.2022 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Uc I Zs.89: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
2022 Volume 92, Issue 11, Page(s) 3114
| MeSH term(s) | Humans ; Indigenous Peoples ; Native Hawaiian or Other Pacific Islander ; Surgeons |
|---|---|
| Language | English |
| Publishing date | 2022-11-17 |
| Publishing country | Australia |
| Document type | Letter ; Comment |
| ZDB-ID | 2050749-5 |
| ISSN | 1445-2197 ; 1445-1433 ; 0004-8682 |
| ISSN (online) | 1445-2197 |
| ISSN | 1445-1433 ; 0004-8682 |
| DOI | 10.1111/ans.18102 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 180: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
ACS chemical biology
2024 Volume 19, Issue 4, Page(s) 981–991
Abstract: The development of new antimicrobial agents effective against Gram-negative bacteria remains a major challenge in drug discovery. The lasso peptide cloacaenodin has potent antimicrobial activity against multiple strains in ... ...
| Abstract | The development of new antimicrobial agents effective against Gram-negative bacteria remains a major challenge in drug discovery. The lasso peptide cloacaenodin has potent antimicrobial activity against multiple strains in the |
|---|---|
| MeSH term(s) | Antimicrobial Peptides ; Anti-Bacterial Agents/pharmacology ; Membrane Transport Proteins ; Anti-Infective Agents ; Peptides ; Bacteria |
| Chemical Substances | Antimicrobial Peptides ; Anti-Bacterial Agents ; Membrane Transport Proteins ; Anti-Infective Agents ; Peptides |
| Language | English |
| Publishing date | 2024-03-25 |
| Publishing country | United States |
| Document type | Journal Article |
| ISSN | 1554-8937 |
| ISSN (online) | 1554-8937 |
| DOI | 10.1021/acschembio.4c00009 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
International journal of epidemiology
1989 Volume 18, Issue 4, Page(s) 808–817
Abstract: A ten-year community survey was undertaken to investigate the high coronary heart disease (CHD) incidence among people of Indian (South Asian) descent in Trinidad, West Indies. Of 2491 individuals aged 35-69 years, 2215 (89%) were examined and 2069 (83%) ...
| Abstract | A ten-year community survey was undertaken to investigate the high coronary heart disease (CHD) incidence among people of Indian (South Asian) descent in Trinidad, West Indies. Of 2491 individuals aged 35-69 years, 2215 (89%) were examined and 2069 (83%) found to be clinically free of CHD at baseline. After exclusion of 71 of minority ethnic groups, 786 African, 598 Indian, 147 European and 467 adults of Mixed descent were followed for CHD morbidity and mortality. In both sexes, adults of Indian origin had higher prevalence rates of diabetes mellitus, a low concentration of high-density lipoprotein (HDL) cholesterol, and recent abstinence from alcohol than other ethnic groups. Indian men also had larger skinfold thicknesses than other men. In participants free of CHD at entry, the age-adjusted relative risk of a cardiac event believed due to CHD was at least twice as high in Indian men and women as in other ethnic groups. In men, blood pressure, diabetes mellitus and low-density lipoprotein (LDL) cholesterol concentration were positively and independently related to risk of CHD, whereas alcohol consumption and HDL cholesterol concentration were inversely associated with risk after allowing for age and ethnic group. The ethnic contrasts in CHD persisted when these characteristics were taken into account. In the smaller sample of women, only ethnic group was predictive of CHD as defined. The failure of point estimates of risk to explain the high CHD incidence in Indians calls for focus on age of onset of risk and examination of other potential risk factors such as insulin concentration. |
|---|---|
| MeSH term(s) | Adult ; Africa/ethnology ; Aged ; China/ethnology ; Cholesterol, HDL/blood ; Coronary Disease/blood ; Coronary Disease/epidemiology ; Coronary Disease/ethnology ; Developing Countries/statistics & numerical data ; Europe/ethnology ; Female ; Follow-Up Studies ; Humans ; India/ethnology ; Linear Models ; Male ; Middle Aged ; Middle East/ethnology ; Prognosis ; Proportional Hazards Models ; Risk Factors ; Trinidad and Tobago/epidemiology |
| Chemical Substances | Cholesterol, HDL |
| Language | English |
| Publishing date | 1989-12 |
| Publishing country | England |
| Document type | Journal Article ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 187909-1 |
| ISSN | 1464-3685 ; 0300-5771 |
| ISSN (online) | 1464-3685 |
| ISSN | 0300-5771 |
| DOI | 10.1093/ije/18.4.808 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 893: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
2023 Volume 14, Page(s) 1283674
Abstract: FOLFOX (5-fluorouracil, leucovorin, oxaliplatin) chemotherapy is a treatment for colorectal cancer that can induce persistent fatigue and metabolic dysfunction. Regular exercise after chemotherapy cessation is widely recommended for cancer patients and ... ...
| Abstract | FOLFOX (5-fluorouracil, leucovorin, oxaliplatin) chemotherapy is a treatment for colorectal cancer that can induce persistent fatigue and metabolic dysfunction. Regular exercise after chemotherapy cessation is widely recommended for cancer patients and has been shown to improve fatigue resistance in mice. However, gaps remain in understanding whether the early systemic and skeletal muscle adaptations to regular exercise are altered by prior FOLFOX chemotherapy treatment. Furthermore, the effects of exercise duration on early metabolic and skeletal muscle transcriptional adaptations are not fully established. |
|---|---|
| Language | English |
| Publishing date | 2023-11-01 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 2564217-0 |
| ISSN | 1664-042X |
| ISSN | 1664-042X |
| DOI | 10.3389/fphys.2023.1283674 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
Journal of affective disorders
2024 Volume 355, Page(s) 115–121
Abstract: Background: Posttraumatic stress disorder (PTSD) is a psychiatric condition characterized by a prolonged stress response to potentially life-threatening events long after the event has passed. Understanding factors related to recovery from traumatic ... ...
| Abstract | Background: Posttraumatic stress disorder (PTSD) is a psychiatric condition characterized by a prolonged stress response to potentially life-threatening events long after the event has passed. Understanding factors related to recovery from traumatic life events may inform novel targets for intervention. There is emerging preclinical evidence that creatine (Cr), a molecule critical to brain bioenergetics, may be a neurobiological marker of stress reactivity and recovery. Method: 25 US Veterans (8 female) completed the Life Events Checklist for DSM-5, which assessed different types of traumatic events. Veterans were also asked to rate the subjective stress of each traumatic event on a 1-10 scale currently (Current Stress) and at the time the event occurred (Past Stress). Stress recovery was quantified as the difference between Current and Past Stress. Current PTSD symptoms were also assessed using the PTSD Checklist for DSM-5. Cr concentrations in the anterior cingulate cortex (ACC) were measured in the anterior cingulate cortex using proton magnetic resonance spectroscopy (1H-MRS). Results: Higher levels of Cr were associated with self-reported stress recovery from participants' most traumatic life event. Cr was not related to number of different types of traumatic life events or current PTSD symptoms. Limitations: The sample size was relatively small. Stress recovery was measured via retrospective self-report. Future experimental work in humans should clarify the protective role of Cr in recovery from trauma. Conclusions: ACC concentrations of Cr may be an important neurochemical factor related to stress recovery. Future work should investigate Cr as a possible protective factor against the effects of traumatic stress. |
|---|---|
| MeSH term(s) | Humans ; Female ; Gyrus Cinguli/diagnostic imaging ; Creatine ; Veterans/psychology ; Retrospective Studies ; Stress Disorders, Post-Traumatic/diagnosis ; Stress Disorders, Post-Traumatic/psychology |
| Chemical Substances | Creatine (MU72812GK0) |
| Language | English |
| Publishing date | 2024-03-26 |
| Publishing country | Netherlands |
| Document type | Journal Article |
| ZDB-ID | 135449-8 |
| ISSN | 1573-2517 ; 0165-0327 |
| ISSN (online) | 1573-2517 |
| ISSN | 0165-0327 |
| DOI | 10.1016/j.jad.2024.03.152 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
| Zs.A 1485: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
Microbiology resource announcements
2023 Volume 12, Issue 12, Page(s) e0091023
Abstract: We report here the draft genome sequences ... ...
| Abstract | We report here the draft genome sequences of |
|---|---|
| Language | English |
| Publishing date | 2023-11-16 |
| Publishing country | United States |
| Document type | Journal Article |
| ISSN | 2576-098X |
| ISSN (online) | 2576-098X |
| DOI | 10.1128/MRA.00910-23 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
2023 Volume 25, Issue 2, Page(s) 1431–1447
Abstract: Combat exposure (CE) and military sexual trauma (MST) are among the most common types of traumatic experiences faced by veterans and active duty servicemembers and, as such, have both garnered increased research focus over the past decades. However, ... ...
| Abstract | Combat exposure (CE) and military sexual trauma (MST) are among the most common types of traumatic experiences faced by veterans and active duty servicemembers and, as such, have both garnered increased research focus over the past decades. However, there has not yet been a critical review of the literature to examine the distinct clinical presentations associated with different trauma types. This is particularly important, as understanding distinct clinical profiles could help researchers and clinicians refine treatment approaches based on trauma type. To address this question, we conducted a search of the available literature in PsycINFO and PubMed prior to October 2022. We identified 43 articles evaluating the distinct and overlapping clinical symptoms of CE and MST. Study findings were conceptually organized by psychiatric condition. In general, there was substantial variability in study methodology including sample size, composition, and operationalizations of CE and MST. Despite this variability, notable patterns emerged across studies. Specifically, MST and CE uniquely predicted posttraumatic stress disorder symptoms, MST was more related to depressive symptoms and suicidality than CE, and CE appeared to be more related to alcohol use and other externalizing behaviors. Gender also played a significant role in the relationship between CE, MST, and clinical variables across studies. This review suggests that individuals with a history of MST and CE likely have distinct clinical presentations and more research into these presentations could better inform assessment and treatment. Important methodological gaps in the literature are also discussed. |
|---|---|
| MeSH term(s) | Humans ; Veterans ; Military Personnel ; Sex Offenses/psychology ; Military Sexual Trauma ; Mental Health ; Stress Disorders, Post-Traumatic/psychology |
| Language | English |
| Publishing date | 2023-06-14 |
| Publishing country | United States |
| Document type | Journal Article ; Review |
| ZDB-ID | 2070884-1 |
| ISSN | 1552-8324 ; 1524-8380 |
| ISSN (online) | 1552-8324 |
| ISSN | 1524-8380 |
| DOI | 10.1177/15248380231178764 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.