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Article ; Online: Secular trends in sleep and circadian problems among adolescents in Hong Kong: From 2011-2012 to 2017-2019.

Chen, Chris Xie / Zhang, Ji-Hui / Li, Shirley Xin / Chan, Kate Ching Ching / Li, Albert Martin / Kong, Alice Pik Shan / Chan, Joey Wing Yan / Wing, Yun Kwok / Chan, Ngan Yin

Sleep medicine

2024 Volume 117, Page(s) 62–70

Abstract: ... in Hong Kong Chinese adolescents.: Methods: This study analyzed cross-sectional data from two large-scale school ... boys]) were included in this 7-year study. The average time in bed of Hong Kong adolescents decreased ...

Abstract	Objective: The study aimed to investigate secular trends in sleep and circadian problems in Hong Kong Chinese adolescents. Methods: This study analyzed cross-sectional data from two large-scale school-based sleep surveys conducted in 2011-2012 and 2017-2019. Sleep and circadian problems, including sleep-wake pattern, insomnia, chronotype, social jetlag, daytime sleepiness, and other sleep-related factors, were compared between two survey years. Results: A total of 8082 adolescents (5639 students in 2011-2012 [Mean age: 14.4 years, 50.9% boys] and 2443 students in 2017-2019 [Mean age: 14.7 years, 54.0% boys]) were included in this 7-year study. The average time in bed of Hong Kong adolescents decreased from 8.38 hours to 8.08 hours from 2011-2012 to 2017-2019. There was a 0.28-hour delay in weekday bedtime, 0.54-hour advance in weekend wake-up time, and a 0.36-hour decline in average time in bed, resulting in increased trends of sleep loss (Time in bed <8h: OR = 2.06, 95%CI: 1.44-2.93, p < 0.01; Time in bed <7h: OR = 2.73, 95%CI: 1.92-3.89, p < 0.01), daytime sleepiness (OR = 1.70, 95%CI: 1.34-2.16, p < 0.01), and evening chronotype (OR = 1.26, 95%CI: 1.08-1.48, p < 0.01). The increased trend in insomnia disorder, however, was insignificant when covariates were adjusted. Conclusion: A secular trend of reduced time in bed, delay in weekday bedtime, advance in weekend wake-up time, increase in evening chronotype and daytime sleepiness from 2011-2012 to 2017-2019 were observed. There is a timely need for systematic intervention to promote sleep health in adolescents.
MeSH term(s)	Male ; Humans ; Adolescent ; Female ; Hong Kong/epidemiology ; Circadian Rhythm ; Cross-Sectional Studies ; Sleep ; Disorders of Excessive Somnolence/epidemiology ; Surveys and Questionnaires
Language	English
Publishing date	2024-03-11
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2012041-2
ISSN	1878-5506 ; 1389-9457
ISSN (online)	1878-5506
ISSN	1389-9457
DOI	10.1016/j.sleep.2024.03.003
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Article ; Online: Advance Care Planning in Hong Kong.

Chan, Carmen W H / Chen, Yong-Feng / Chan, Helen Y L

Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen

2023 Volume 180, Page(s) 90–93

Abstract: Hong Kong is a well-developed city with outstanding healthcare services, leading to the highest ...

Abstract	Hong Kong is a well-developed city with outstanding healthcare services, leading to the highest life expectancy in the world. Paradoxically, the quality of end-of-life care in this city lagged behind that of many other high-income regions. Possibly, the advances in medicine contribute to the death denial culture, hindering communication about end-of-life care. This paper discusses challenges arisen due to poor public awareness and professional training and local initiatives to promote advance care planning in the community.
MeSH term(s)	Humans ; Hong Kong ; Germany ; Advance Care Planning ; Medicine
Language	English
Publishing date	2023-07-01
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2412512-X
ISSN	2212-0289 ; 1865-9217
ISSN (online)	2212-0289
ISSN	1865-9217
DOI	10.1016/j.zefq.2023.05.015
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Article ; Online: Compound floods in Hong Kong

Yangchen Lai / Jianfeng Li / Yongqin David Chen / Faith Ka Shun Chan / Xihui Gu / Shengzhi Huang

Journal of Hydrology: Regional Studies, Vol 46, Iss , Pp 101321- (2023)

Hazards, triggers, and socio-economic consequences

2023

Abstract: Study region: Hong Kong is a megalopolis located on the southeast coast of China. Study focus ... Megalopolis located in low-lying coastal areas such as Hong Kong is especially vulnerable to compound flood ... socio-economic impacts of compound floods from precipitation and sea level in Hong Kong. New hydrological ...

Abstract	Study region: Hong Kong is a megalopolis located on the southeast coast of China. Study focus: Megalopolis located in low-lying coastal areas such as Hong Kong is especially vulnerable to compound flood risks from multiple flood drivers (e.g., heavy rainstorms and extreme sea levels). Using long-term hydrological observations and socio-economic data, this study aims to reveal the risks, causes and socio-economic impacts of compound floods from precipitation and sea level in Hong Kong. New hydrological insights for the region: We find that the most extreme sea levels are mostly accompanied by heavy precipitation and thus lead to compound floods, while the most extreme precipitation events are less likely to coincide with extreme sea levels. TCs are the major trigger of compound floods with fractional contributions ranging from 48.8% to 83.8% in the gauges. Typhoon Wanda (1962) triggered the most severe compound flood with a joint return period of 178 years which is much shorter than the return period (>10,000 years) without the consideration of the dependence between the extremes. During the past decades, Hong Kong has experienced an increase in compound flood hazards, which is mainly attributed to the mean sea level rise. Socio-economic data reveals that TCs associated with compound floods are more destructive than TCs that induced single-type floods, highlighting the urgent need to establish a multi-hazard flood risk management strategy.
Keywords	Compound floods ; Extreme sea levels ; Tropical cyclones ; Socio-economic damage ; Hong Kong ; Physical geography ; GB3-5030 ; Geology ; QE1-996.5
Subject code	910
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
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Article ; Online: Chinese Virtues and Resilience among Students in Hong Kong.

Kuang, Xiaoxue / Lee, John Chi-Kin / Chen, Junjun

International journal of environmental research and public health

2023 Volume 20, Issue 4

Abstract: ... between students' perceptions of virtues and resilience in Hong Kong, SAR, China. A total of 2468 pupils ... from primary and secondary schools in Hong Kong were recruited as the sample for this study. The results ...

Abstract	Character strengths and training have a great impact on students' whole-person development. This study examined the applicability of the Chinese virtues questionnaire (CVQ) and the relationships between students' perceptions of virtues and resilience in Hong Kong, SAR, China. A total of 2468 pupils from primary and secondary schools in Hong Kong were recruited as the sample for this study. The results of confirmatory factor analysis (CFA) supported a measurement model of Chinese virtues, and the results of structural equation modeling (SEM) suggested that Chinese virtues were positively related to positive resilience and succumbing. Significant relationships were found between gender and students' positive resilience, and school grade level showed a significant impact on the Chinese virtues, which in turn affect resilience. Student resilience could be enhanced by nurturing virtues and related character strengths, keeping in mind the role of gender and grade level.
MeSH term(s)	Humans ; Hong Kong ; Virtues ; East Asian People ; China ; Students ; Surveys and Questionnaires
Language	English
Publishing date	2023-02-20
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph20043769
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Article ; Online: Association of COVID-19 vaccination with duration of hospitalization in older adults in Hong Kong.

Chen, Dongxuan / Cowling, Benjamin J / Ainslie, Kylie E C / Lin, Yun / Wong, Jessica Y / Lau, Eric H Y / Wu, Peng / Nealon, Joshua

Vaccine

2024 Volume 42, Issue 9, Page(s) 2385–2393

Abstract: ... 19 patients during Omicron waves in Hong Kong, and explore potential predictors.: Methods ... infection in Hong Kong in 2022, from 1 February to 22 November, and with 28 days of follow-up ...

Abstract	Introduction: The association between COVID-19 vaccination and length of hospital stay may provide further insight into vaccination benefits, but few studies have investigated such associations in detail. We aimed to investigate the association between COVID-19 vaccination and length of hospital stay in COVID-19 patients during Omicron waves in Hong Kong, and explore potential predictors. Methods: This retrospective cohort study was conducted on local patients aged ≥60 years who were admitted due to COVID-19 infection in Hong Kong in 2022, from 1 February to 22 November, and with 28 days of follow-up since admission. The exposure was either not vaccinated; or having received 2/3/4 doses of CoronaVac (Sinovac); or 2/3/4 doses of BNT162b2 (BioNTech/Fosun Pharma/Pfizer). Length of stay in hospital was the main outcome. Accelerated failure time models were used to quantify variation in hospital stay for vaccinated compared with unvaccinated patients, accounting for age, sex, comorbidity, type of vaccine and number of doses received, care home residence and admission timing; stratified by age groups and epidemic waves. Results: This study included 32,398 patients aged 60 years and above for main analysis, their median (IQR) age was 79 (71-87) years, 53% were men, and 40% were unvaccinated. The patients were stratified by confirmation prior to or since 23 May 2022, resulting in a sample size of 15,803 and 16,595 in those two waves respectively. Vaccinated patients were found to have 13-39% shorter hospital stay compared to unvaccinated patients. More vaccine doses received were associated with shorter hospital stay, and BNT162b2 recipients had slightly shorter hospital stays than CoronaVac recipients. Conclusion: Vaccination was associated with reduced hospital stay in breakthrough infections. Increased vaccination uptake in older adults may improve hospital bed turnover and public health outcomes especially during large community epidemics.
MeSH term(s)	Male ; Humans ; Aged ; Female ; BNT162 Vaccine ; Hong Kong/epidemiology ; COVID-19 Vaccines ; Retrospective Studies ; COVID-19/epidemiology ; COVID-19/prevention & control ; Hospitalization ; Vaccination
Chemical Substances	BNT162 Vaccine ; COVID-19 Vaccines
Language	English
Publishing date	2024-03-05
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	605674-x
ISSN	1873-2518 ; 0264-410X
ISSN (online)	1873-2518
ISSN	0264-410X
DOI	10.1016/j.vaccine.2024.02.074
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Zs.A 1930: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: The Correlates of Academic Stress in Hong Kong.

Chyu, Esther Pui Yung / Chen, Ji-Kang

International journal of environmental research and public health

2022 Volume 19, Issue 7

Abstract: ... to predict academic stress in Hong Kong. One thousand eight hundred and four students from eight secondary ... schools in Hong Kong participated in this study. The results indicate that perfectionism, social-oriented ...

Abstract	Most previous studies have attempted to explore how different personal, familial, or school factors are linked to academic stress in Western countries. However, relatively less research has incorporated these different factors into one model to examine the most crucial correlate(s) that predict academic stress, particularly in the East Asian context, where the level of academic stress among adolescents is high. This study examined how perfectionism, social-oriented achievement motivation, parental aspiration for achievement, parent-child relationship, emphasis on academics in school, and school climate work together to predict academic stress in Hong Kong. One thousand eight hundred and four students from eight secondary schools in Hong Kong participated in this study. The results indicate that perfectionism, social-oriented achievement motivation, parent-child relationships, and emphasis on academics in school have significant associations with academic stress, while perfectionism and social-oriented achievement motivation, the two factors from the personal domain, are the dominant drivers of academic stress. In addition, these findings applied to both genders. As the significant correlates come from the personal, familial, and school domains, this study recommends multilevel interventions for decreasing the level of academic stress. In addition, this study also suggests further research directions to examine the psychosocial mechanism between the correlates and academic stress.
MeSH term(s)	Achievement ; Adolescent ; Female ; Hong Kong ; Humans ; Male ; Motivation ; Schools ; Students/psychology
Language	English
Publishing date	2022-03-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph19074009
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Article ; Online: Multimodal digital assessment of depression with actigraphy and app in Hong Kong Chinese.

Chen, Jie / Chan, Ngan Yin / Li, Chun-Tung / Chan, Joey W Y / Liu, Yaping / Li, Shirley Xin / Chau, Steven W H / Leung, Kwong Sak / Heng, Pheng-Ann / Lee, Tatia M C / Li, Tim M H / Wing, Yun-Kwok

Translational psychiatry

2024 Volume 14, Issue 1, Page(s) 150

Abstract: There is an emerging potential for digital assessment of depression. In this study, Chinese patients with major depressive disorder (MDD) and controls underwent a week of multimodal measurement including actigraphy and app-based measures (D-MOMO) to ... ...

Abstract	There is an emerging potential for digital assessment of depression. In this study, Chinese patients with major depressive disorder (MDD) and controls underwent a week of multimodal measurement including actigraphy and app-based measures (D-MOMO) to record rest-activity, facial expression, voice, and mood states. Seven machine-learning models (Random Forest [RF], Logistic regression [LR], Support vector machine [SVM], K-Nearest Neighbors [KNN], Decision tree [DT], Naive Bayes [NB], and Artificial Neural Networks [ANN]) with leave-one-out cross-validation were applied to detect lifetime diagnosis of MDD and non-remission status. Eighty MDD subjects and 76 age- and sex-matched controls completed the actigraphy, while 61 MDD subjects and 47 controls completed the app-based assessment. MDD subjects had lower mobile time (P = 0.006), later sleep midpoint (P = 0.047) and Acrophase (P = 0.024) than controls. For app measurement, MDD subjects had more frequent brow lowering (P = 0.023), less lip corner pulling (P = 0.007), higher pause variability (P = 0.046), more frequent self-reference (P = 0.024) and negative emotion words (P = 0.002), lower articulation rate (P < 0.001) and happiness level (P < 0.001) than controls. With the fusion of all digital modalities, the predictive performance (F1-score) of ANN for a lifetime diagnosis of MDD was 0.81 and 0.70 for non-remission status when combined with the HADS-D item score, respectively. Multimodal digital measurement is a feasible diagnostic tool for depression in Chinese. A combination of multimodal measurement and machine-learning approach has enhanced the performance of digital markers in phenotyping and diagnosis of MDD.
MeSH term(s)	Humans ; Depressive Disorder, Major/diagnosis ; Bayes Theorem ; Actigraphy ; Depression/diagnosis ; Hong Kong ; Mobile Applications
Language	English
Publishing date	2024-03-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2609311-X
ISSN	2158-3188 ; 2158-3188
ISSN (online)	2158-3188
ISSN	2158-3188
DOI	10.1038/s41398-024-02873-4
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Article ; Online: Clinical outcomes following discontinuation of metformin in patients with type 2 diabetes and advanced chronic kidney disease in Hong Kong: a territory-wide, retrospective cohort and target trial emulation study.

Yang, Aimin / Shi, Mai / Wu, Hongjiang / Lau, Eric Sh / Cheung, Johnny Tk / Zhang, Xinge / Fan, Baoqi / Chen, Tingting / Kong, Alice Ps / Luk, Andrea Oy / Ma, Ronald Cw / Chan, Juliana Cn / Chow, Elaine

EClinicalMedicine

2024 Volume 71, Page(s) 102568

Abstract: ... trial emulation study, we included Chinese patients attending the Hong Kong Hospital Authority (HA) and ...

Abstract	Background: Current labelling advises discontinuation of metformin when estimated glomerular filtration rate (eGFR) < 30 ml/min/1.73 m Methods: In this territory-wide, retrospective cohort and target trial emulation study, we included Chinese patients attending the Hong Kong Hospital Authority (HA) and enrolled in the Risk-Assessment-and-Management-Programme-for-Diabetes-Mellitus (RAMP-DM) from 2002 to 2019. Patients were stratified by discontinuation of metformin within six months after reaching eGFR < 30 ml/min/1.73 m Findings: A total of 33,586 metformin users with new-onset eGFR < 30 ml/min/1.73 m Interpretation: Our results suggest that discontinuation of metformin in patients with T2D and chronic kidney disease may be associated with increased risk of cardiovascular-renal events. Use of metformin below eGFR of 30 ml/min/1.73 m Funding: CUHK Impact Research Fellowship Scheme.
Language	English
Publishing date	2024-03-28
Publishing country	England
Document type	Journal Article
ISSN	2589-5370
ISSN (online)	2589-5370
DOI	10.1016/j.eclinm.2024.102568
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Article: Modernising postgraduate medical education: evolving roles of The Hong Kong Jockey Club Innovative Learning Centre for Medicine in the Hong Kong Academy of Medicine.

Chen, P P / So, H Y / Lo, J S T / Cheng, B C P

Hong Kong medical journal = Xianggang yi xue za zhi

2023 Volume 29, Issue 6, Page(s) 480–483

MeSH term(s)	Humans ; Hong Kong ; Education, Medical ; Learning
Language	English
Publishing date	2023-12-04
Publishing country	China
Document type	Editorial
ZDB-ID	1239255-8
ISSN	1024-2708
ISSN	1024-2708
DOI	10.12809/hkmj2311178
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Zs.A 4347: Show issues

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Article ; Online: Association of insomnia with incident chronic cognitive impairment in older adults with type 2 diabetes mellitus: A prospective study of the Hong Kong Diabetes Register.

O, Chun-Kwan / Siu, Brian Wai-Hei / Leung, Vanessa Wai-Shan / Lin, Yuan-Yuan / Ding, Chen-Zhao / Lau, Eric Siu-Him / Luk, Andrea On-Yan / Chow, Elaine Yee-Kwan / Ma, Ronald Ching-Wan / Chan, Juliana Chung-Ngor / Chan, Rachel Ngan-Yin / Wing, Yun Kwok / Kong, Alice Pik-Shan

Journal of diabetes and its complications

2023 Volume 37, Issue 10, Page(s) 108598

Abstract: ... with T2D aged ≥60 years enrolled in the Hong Kong Diabetes Register completed the Insomnia Severity Index ...

Abstract	Aims: To examine the risk association of insomnia with incident chronic cognitive impairment in older adults with type 2 diabetes mellitus (T2D). Methods: Between July 2010 and June 2015, patients with T2D aged ≥60 years enrolled in the Hong Kong Diabetes Register completed the Insomnia Severity Index (ISI) questionnaire. Patients were considered having insomnia if they had ISI score > 14. We prospectively followed up the cohort and censored outcome through reviewing diagnoses and clinical notes entered by attending physicians in electronic medical record to identify incident cases of mild cognitive impairment and dementia. Results: After excluding shift workers and those with established chronic cognitive impairment at baseline, we included 986 patients with T2D in this study (58.3 % men, mean age ± standard deviation: 62.5 ± 2.6 years, disease duration of diabetes: 10.7 ± 8.2 years, HbA1c: 7.4 ± 1.3 %, insulin users: 28.7 %, insomnia: 9.1 %). After a median follow-up of 7.6 (interquartile range = 2.0) years, 41 (4.2 %) developed chronic cognitive impairment. Using Cox regression analysis, insomnia (hazard ratio, HR 2.909, p = 0.012) and HbA1c ≥ 7 % (HR 2.300, p = 0.038) were positively associated with incident chronic cognitive impairment while insulin use (HR 0.309, p = 0.028) showed negative association. Conclusions: Insomnia, suboptimal glycemic control and non-insulin use are independent risk factors for incident chronic cognitive impairment in older adults with T2D.
MeSH term(s)	Male ; Humans ; Aged ; Female ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/epidemiology ; Prospective Studies ; Glycated Hemoglobin ; Hong Kong/epidemiology ; Sleep Initiation and Maintenance Disorders/complications ; Sleep Initiation and Maintenance Disorders/epidemiology ; Risk Factors ; Cognitive Dysfunction/complications ; Cognitive Dysfunction/epidemiology ; Insulin
Chemical Substances	Glycated Hemoglobin ; Insulin
Language	English
Publishing date	2023-09-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	1105840-7
ISSN	1873-460X ; 1056-8727
ISSN (online)	1873-460X
ISSN	1056-8727
DOI	10.1016/j.jdiacomp.2023.108598
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