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  1. Article: An impression of Anna M. Baetjer.

    Corn, J K

    American Industrial Hygiene Association journal

    1992  Volume 53, Issue 9, Page(s) A441–4

    MeSH term(s) Baltimore ; Environmental Health/history ; History, 20th Century ; Humans ; Occupational Medicine/education ; Occupational Medicine/history ; Women's Rights/history
    Language English
    Publishing date 1992-09
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article ; Portrait
    ZDB-ID 210659-0
    ISSN 0002-8894 ; 0096-820X
    ISSN 0002-8894 ; 0096-820X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pituitary apoplexy during pregnancy with transsphenoidal resection and intraoperative fetal monitoring: A case report.

    Corn, Megan / Nickell, Austin / Lessard, Collette / Jackson, Adam

    Case reports in women's health

    2023  Volume 39, Page(s) e00543

    Abstract: Introduction: Prolactinomas resulting in pituitary apoplexy are an uncommon obstetrical complication. The hemorrhage can cause compression and necrosis of the pituitary gland as well as the optic chiasm, necessitating surgical intervention.: Case: A ... ...

    Abstract Introduction: Prolactinomas resulting in pituitary apoplexy are an uncommon obstetrical complication. The hemorrhage can cause compression and necrosis of the pituitary gland as well as the optic chiasm, necessitating surgical intervention.
    Case: A 35-year-old woman, G0, presented for an infertility consult with a prior diagnosis of polycystic ovarian syndrome. Evaluation for oligomenorrhea found an elevated prolactin level of 69.76 ng/mL, an elevated DHEA-S of 524, and HgbA1c of 5.7%. The patient denied visual or neurological symptoms. Infertility treatment was started, and magnetic resonance imaging (MRI) of the brain was recommended; however, the patient forewent imaging. Within a few months, she was pregnant. At 27 weeks of gestation, the patient developed sudden visual field loss to the right eye and presented to her optometrist. MRI of the pituitary identified a sellar mass with suprasellar extension, consistent with a recently hemorrhaged pituitary macroadenoma or pituitary apoplexy with displacement of the optic chiasm. Due to the risks of permanent optic nerve damage, the patient underwent endoscopic endonasal transsphenoidal hypophysectomy with intraoperative fetal monitoring at 30 weeks 1 day of gestation. At 39 weeks of gestation a cesarean section was performed due to the recent procedure. Her delivery and postpartum period were without complications.
    Discussion: Pituitary apoplexy presenting in pregnancy is a rare and potentially life-threatening disorder due to an acute ischemic infarction or hemorrhage of the pituitary gland. Surgical management of the pituitary gland in pregnancy is rarely recommended, except in cases of severe visual disturbance and uncontrolled Cushing's disease.
    Language English
    Publishing date 2023-09-17
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2800286-6
    ISSN 2214-9112 ; 2214-9112
    ISSN (online) 2214-9112
    ISSN 2214-9112
    DOI 10.1016/j.crwh.2023.e00543
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Coming of Age of Breast Radiotherapy.

    Corn, Benjamin W / Galper, Shira / Ben-David, Merav

    Current oncology (Toronto, Ont.)

    2023  Volume 30, Issue 5, Page(s) 5179–5181

    Abstract: Exactly 50 years ago, the investigators of the National Surgical Adjuvant Breast and Bowel Project began to design the B-06 trial [ ... ]. ...

    Abstract Exactly 50 years ago, the investigators of the National Surgical Adjuvant Breast and Bowel Project began to design the B-06 trial [...].
    Language English
    Publishing date 2023-05-19
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 1236972-x
    ISSN 1718-7729 ; 1198-0052
    ISSN (online) 1718-7729
    ISSN 1198-0052
    DOI 10.3390/curroncol30050392
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Adverse Fetal Outcomes and Histopathology of Placentas Affected by COVID-19: A Report of Four Cases.

    Corn, Megan / Pham, Truc / Kemp, Walter

    Cureus

    2023  Volume 15, Issue 8, Page(s) e44402

    Abstract: Coronavirus disease 2019 (COVID-19) has had significant impacts on mothers and neonates. In this report, we present four unique cases of COVID-19 infections in pregnancy and its effects on the mother, fetus, and placenta. Four mothers presented to the ... ...

    Abstract Coronavirus disease 2019 (COVID-19) has had significant impacts on mothers and neonates. In this report, we present four unique cases of COVID-19 infections in pregnancy and its effects on the mother, fetus, and placenta. Four mothers presented to the hospital during their pregnancy. Each had tested COVID-19-positive 1-29 days prior to admission. Gestational age ranged from 16 weeks six days to 36 weeks six days. Three of the four cases resulted in fetal demise or infant expiration. The common finding among all four cases was pathologic changes in the placenta. Most of the placentas were small for gestational age and had extensive villous infarction. There was also histiocytic intervillositis with villous necrosis and perivillous fibrin deposition. The placentas demonstrated positive staining of syncytiotrophoblasts for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike S1 subunit protein. SARS-CoV-2 RNA was detected in tissue samples of two of the fetuses demonstrating vertical transmission. A higher incidence of severe COVID-19 disease course has been observed in pregnant women. Prior to the SARS-CoV-2 pandemic, chorionic histiocytic intervillositis of the placenta was rarely seen, and mostly of unknown etiology. The increase in placental fibrin levels results in decreased maternal placenta blood flow ensuing hypoxic stress in the fetus. Intrauterine hypoxia has been associated with alterations in brain structure and function resulting in defects in motor skills, cerebral palsy, decreased brain weight, schizophrenia, and other forms of cognitive impairment.
    Language English
    Publishing date 2023-08-30
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.44402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Age-related differences in social media use, online social support, and depressive symptoms in adolescents and emerging adults.

    Politte-Corn, Madison / Nick, Elizabeth A / Kujawa, Autumn

    Child and adolescent mental health

    2023  Volume 28, Issue 4, Page(s) 497–503

    Abstract: Background: Despite growing concerns about the impact of social media use on the developing brain and associated mental health impacts, whether susceptibility to the benefits and harms of social media use changes across adolescence and young adulthood ... ...

    Abstract Background: Despite growing concerns about the impact of social media use on the developing brain and associated mental health impacts, whether susceptibility to the benefits and harms of social media use changes across adolescence and young adulthood has yet to be empirically tested.
    Method: Using a cross-sectional sample of participants aged 14-22 years (N = 254), we examined (a) linear and non-linear age-related changes in social media use and online social support and (b) age-related differences in the effects of social media use and online social support on depressive symptoms.
    Results: We found age differences in social media use, but not online social support, such that social media use increased across adolescence and peaked around age 20, followed by stable use into young adulthood. Age moderated the effect of online social support, but not overall social media use, on depressive symptoms, such that online social support was negatively associated with depressive symptoms for adolescents (age < 16.98), but the opposite pattern emerged for young adults (age > 19.04).
    Conclusions: Results suggest overall developmental changes in social media use and that adolescents may be more susceptible than emerging adults to the beneficial effects of positive online interactions on mental health.
    MeSH term(s) Young Adult ; Humans ; Adolescent ; Adult ; Depression ; Social Media ; Cross-Sectional Studies ; Social Support ; Mental Health
    Language English
    Publishing date 2023-02-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2073663-0
    ISSN 1475-3588 ; 1475-357X
    ISSN (online) 1475-3588
    ISSN 1475-357X
    DOI 10.1111/camh.12640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Scleredema in the Setting of Monoclonal Gammopathy of Unknown Significance With Progression to Multiple Myeloma: A Case Report.

    Nickell, Austin L / Corn, Megan / Mannuru, Devendranath / Hinze, Alicia M

    Cureus

    2023  Volume 15, Issue 9, Page(s) e44968

    Abstract: Type 2 scleredema on the background of monoclonal gammopathy of undetermined significance (MGUS) is a rare and progressive connective tissue disorder with very few cases reported to date. It is characterized by chronic and diffuse induration of the skin ... ...

    Abstract Type 2 scleredema on the background of monoclonal gammopathy of undetermined significance (MGUS) is a rare and progressive connective tissue disorder with very few cases reported to date. It is characterized by chronic and diffuse induration of the skin that begins in the upper back and neck and progresses proximally to distally, involving the shoulders, trunk, and arms; the hands are usually spared. Here, we present an unusual case of long-standing scleredema that progressed to involve the hands and fingers. This case was further complicated by new-onset Raynaud's phenomenon, splenomegaly, lymphadenopathy, the development of a plasmacytoma, and eventual progression to multiple myeloma. We highlight the differential diagnoses for his complex presentation, the workup that was completed, and current treatment options.
    Language English
    Publishing date 2023-09-09
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.44968
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Timely patient access affects appointment retention.

    Corn, Michelle

    MGMA connexion

    2016  Volume 16, Issue 4, Page(s) 45–47

    MeSH term(s) Appointments and Schedules ; Health Services Accessibility ; Humans
    Language English
    Publishing date 2016-07-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2073879-1
    ISSN 1537-0240 ; 0025-7257
    ISSN 1537-0240 ; 0025-7257
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effectiveness of low-density lipoprotein cholesterol reduction with lipid lowering therapy for secondary prevention amongst older individuals: a nationwide cohort study.

    Andersson, Niklas W / Corn, Giulia / Dohlmann, Tine L / Melbye, Mads / Wohlfahrt, Jan / Lund, Marie

    Age and ageing

    2024  Volume 53, Issue 1

    Abstract: Background: Data about the clinical benefit from initial low-density lipoprotein cholesterol (LDL-C) reduction with lipid lowering treatment for secondary prevention and risk of major vascular events amongst older as compared with younger individuals ... ...

    Abstract Background: Data about the clinical benefit from initial low-density lipoprotein cholesterol (LDL-C) reduction with lipid lowering treatment for secondary prevention and risk of major vascular events amongst older as compared with younger individuals treated during routine clinical care are limited. We investigated this in a nationwide cohort.
    Methods: Individuals aged ≥ 50 years with a first-time hospitalisation for a cardiovascular event (index event, including acute coronary syndrome, non-haemorrhagic stroke, transient ischaemic attack and coronary revascularisation), 1 January 2008 to 31 October 2018, who subsequently used lipid lowering treatment, and had an LDL-C measurement before and after the event were included. Hazard ratios (HRs) for major vascular events per 1 mmol/L reduction in LDL-C were estimated for the included 21,751 older and 22,681 younger individuals (≥/<70 years old) using Cox regression.
    Results: LDL-C lowering was associated with a 12% lower risk of major vascular events in older individuals per 1 mmol/L reduction in LDL-C (HR 0.88, 95% confidence interval [CI] 0.84-0.93), with no significant difference compared with the risk reduction amongst younger individuals (HR 0.88, 95% CI 0.83-0.93; P-value for difference between age groups: 0.86). The risk reduction was more pronounced when post hoc restricting, as a proxy for compliance, to new users with an LDL-C reduction above the lowest decile for both older (0.81, 95% CI 0.73-0.90) and younger (0.81, 95% CI 0.72-0.91) individuals.
    Conclusions: This study strongly supports a similar relative clinical benefit of LDL-C reduction with lipid lowering treatment for secondary prevention of major vascular events amongst individuals aged ≥70 and <70 years.
    MeSH term(s) Humans ; Aged ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Cholesterol, LDL ; Cohort Studies ; Secondary Prevention ; Risk Reduction Behavior
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Cholesterol, LDL
    Language English
    Publishing date 2024-01-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 186788-x
    ISSN 1468-2834 ; 0002-0729
    ISSN (online) 1468-2834
    ISSN 0002-0729
    DOI 10.1093/ageing/afad241
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Association of vaccination status and severity of SARS-CoV-2 infections in hospitalized patients.

    Guerrero, Dubert / Baker, Thomas / Corn, Megan / Keup, Sean / Nickell, Austin / Cao, Li

    Vaccine: X

    2024  Volume 18, Page(s) 100473

    Abstract: Vaccination is considered the most promising approach for addressing the COVID-19 pandemic. However, even vaccinated people remain at risk. In this study, we examined the association between levels of vaccination and clinical outcomes in hospitalized ... ...

    Abstract Vaccination is considered the most promising approach for addressing the COVID-19 pandemic. However, even vaccinated people remain at risk. In this study, we examined the association between levels of vaccination and clinical outcomes in hospitalized patients. We conducted a retrospective review of adults hospitalized with COVID-19 infection. Of 484 patients, fully vaccinated (OR = 0.49, p = 0.001) and updated patients (OR = 0.46, p = 0.004) had significantly lower probability of critical severity compared to unvaccinated. Vaccination status is significantly related with 30-day mortality (p = 0.005) but not significantly associated with need for respiratory support or ICU stay. Mean length of stay (LOS) of 6.6 days among boosted patients is significantly lower than patients with no vaccination status (10.7 d, p < 0.001). Our study findings provide real-world evidence of the benefit of booster vaccinations against critical infection and death as well as shortcomings in ICU stay, length of stay or need for ventilatory support.
    Language English
    Publishing date 2024-03-13
    Publishing country England
    Document type Journal Article
    ISSN 2590-1362
    ISSN (online) 2590-1362
    DOI 10.1016/j.jvacx.2024.100473
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Social Media Use as a Predictor of Positive and Negative Affect: An Ecological Momentary Assessment Study of Adolescents with and without Clinical Depression.

    Politte-Corn, Madison / Dickey, Lindsay / Abitante, George / Pegg, Samantha / Bean, Christian A L / Kujawa, Autumn

    Research on child and adolescent psychopathology

    2024  Volume 52, Issue 5, Page(s) 743–755

    Abstract: Social media use is common in adolescents, with implications for psychosocial development and the emergence of depression. Yet, little is known about the time-linked connections between social media use and adolescents' affective experiences and how they ...

    Abstract Social media use is common in adolescents, with implications for psychosocial development and the emergence of depression. Yet, little is known about the time-linked connections between social media use and adolescents' affective experiences and how they may differ between depressed and non-depressed youth. We leveraged ecological momentary assessment in adolescents oversampled for current depression to examine (1) associations between social media use and concurrent and later positive and negative affect and (2) sex and presence of a depressive disorder as moderators of these associations. Adolescents aged 14-17 with (n = 48) and without (n = 97) clinical depression, as indicated via clinical interview, reported momentary social media use and positive and negative affect seven times per day for one week. Multilevel modeling indicated that social media use was associated with reduced positive affect both concurrently and at the next assessment. Further, among clinically depressed youth only, social media use was associated with reduced negative affect at the next assessment. Results suggest that social media use may reduce both positive and negative affect, highlighting the nuanced relation between adolescent social media use and emotional health and laying the groundwork for future research to address several open questions.
    MeSH term(s) Humans ; Social Media/statistics & numerical data ; Adolescent ; Female ; Male ; Ecological Momentary Assessment ; Affect ; Depression/psychology ; Depressive Disorder/psychology ; Depressive Disorder/epidemiology ; Adolescent Behavior/psychology
    Language English
    Publishing date 2024-02-20
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 3041907-4
    ISSN 2730-7174 ; 2730-7166
    ISSN (online) 2730-7174
    ISSN 2730-7166
    DOI 10.1007/s10802-024-01177-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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