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  1. Article ; Online: Reply to "Re-sedation after a large dose of flumazenil".

    Masui, Kenichi

    Journal of anesthesia

    2022  Volume 37, Issue 1, Page(s) 162–163

    MeSH term(s) Flumazenil ; Midazolam ; Anesthesia
    Chemical Substances Flumazenil (40P7XK9392) ; Midazolam (R60L0SM5BC)
    Language English
    Publishing date 2022-10-17
    Publishing country Japan
    Document type Letter
    ZDB-ID 1107821-2
    ISSN 1438-8359 ; 0913-8668
    ISSN (online) 1438-8359
    ISSN 0913-8668
    DOI 10.1007/s00540-022-03123-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Caution!! Reappearance of remimazolam effect after a flumazenil bolus: a larger bolus of flumazenil and a lower total remimazolam clearance are higher risks.

    Masui, Kenichi

    Journal of anesthesia

    2022  Volume 37, Issue 1, Page(s) 1–5

    MeSH term(s) Flumazenil ; Benzodiazepines ; Hypnotics and Sedatives
    Chemical Substances remimazolam (7V4A8U16MB) ; Flumazenil (40P7XK9392) ; Benzodiazepines (12794-10-4) ; Hypnotics and Sedatives
    Language English
    Publishing date 2022-09-16
    Publishing country Japan
    Document type Editorial
    ZDB-ID 1107821-2
    ISSN 1438-8359 ; 0913-8668
    ISSN (online) 1438-8359
    ISSN 0913-8668
    DOI 10.1007/s00540-022-03107-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Remimazolam besilate, a benzodiazepine, has been approved for general anesthesia!!

    Masui, Kenichi

    Journal of anesthesia

    2020  Volume 34, Issue 4, Page(s) 479–482

    Language English
    Publishing date 2020-03-10
    Publishing country Japan
    Document type Editorial
    ZDB-ID 1107821-2
    ISSN 1438-8359 ; 0913-8668
    ISSN (online) 1438-8359
    ISSN 0913-8668
    DOI 10.1007/s00540-020-02755-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Monitored Anesthesia Care Under a Combination of Low-Dose Remimazolam Infusion and Flumazenil Antagonism: A Case Report.

    Kamata, Kotoe / Masui, Kenichi

    Cureus

    2023  Volume 15, Issue 10, Page(s) e46728

    Abstract: Remimazolam is a novel benzodiazepine known for its short-acting properties. The safe use of flumazenil antagonism following remimazolam infusion remains a subject of debate. We present a case of monitored anesthesia care managed to be safe through low- ... ...

    Abstract Remimazolam is a novel benzodiazepine known for its short-acting properties. The safe use of flumazenil antagonism following remimazolam infusion remains a subject of debate. We present a case of monitored anesthesia care managed to be safe through low-dose remimazolam infusion and flumazenil antagonism. Pharmacokinetic simulations revealed that low-dose remimazolam was practically useful as one of the components of multimodal sedation/analgesia. Subsequent sedation with the readministration of remimazolam after a dose of flumazenil could also be attained.
    Language English
    Publishing date 2023-10-09
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.46728
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Interpretation of laboratory tests for prevention of the SARS-CoV-2 transmission.

    Masui, Kenichi

    Journal of anesthesia

    2020  Volume 35, Issue 3, Page(s) 374–377

    Abstract: With the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), medical providers should take care to prevent the transmission of SARS-CoV-2 in hospitals including super-spreading. Understanding super-spreading would be useful to reduce ... ...

    Abstract With the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), medical providers should take care to prevent the transmission of SARS-CoV-2 in hospitals including super-spreading. Understanding super-spreading would be useful to reduce future transmission. Some publications have shown clusters of SARS-CoV-2 such as at choir practice and in hospitals. Aerosol can be considered as a primary transmission route. As SARS-CoV-2 stability in aerosol is similar to SARS-CoV-1 with the higher reproductive number of SARS-CoV-2 than SARS-CoV-1, another factor causes rapidly spread-out, e.g. a higher discharge ratio from infected people or a higher viral intake ratio to human body. A basic research suggests higher infectivity of SARS-CoV-2 in the nose than the peripheral lung. Universal masking would be important to prevent the exposure of SARS-CoV-2 droplet to uninfected people. To detect SARS-CoV-2 infection, laboratory tests such as reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assays are applied. Although sensitivity and specificity are provided for the ability of the test, positive or negative prediction values are useful to indicate the possiblity of infection or non-infection in clinical practice. We have to realize that the positive and negative prediction values depend on the sensitivity, specificity, and infection probability of the patient.
    MeSH term(s) Aerosols ; COVID-19 ; Humans ; SARS-CoV-2 ; Sensitivity and Specificity
    Chemical Substances Aerosols
    Keywords covid19
    Language English
    Publishing date 2020-11-07
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1107821-2
    ISSN 1438-8359 ; 0913-8668
    ISSN (online) 1438-8359
    ISSN 0913-8668
    DOI 10.1007/s00540-020-02872-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Correction: Equilibration rate constant, k

    Masui, Kenichi / Hagihira, Satoshi

    Journal of anesthesia

    2022  Volume 36, Issue 6, Page(s) 763

    Language English
    Publishing date 2022-08-19
    Publishing country Japan
    Document type Published Erratum
    ZDB-ID 1107821-2
    ISSN 1438-8359 ; 0913-8668
    ISSN (online) 1438-8359
    ISSN 0913-8668
    DOI 10.1007/s00540-022-03104-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Anesthesia management for thoracoscopic resection of a huge intrathoracic meningocele: a case report.

    Nakazawa, Ryosuke / Masui, Kenichi / Goto, Takahisa

    JA clinical reports

    2024  Volume 10, Issue 1, Page(s) 14

    Abstract: Background: Diagnosed intrathoracic meningocele is an uncommon complication of neurofibromatosis type 1. We report an anesthesia management for a rare case undergoing thoracoscopic resection of a huge intrathoracic meningocele.: Case presentation: A ... ...

    Abstract Background: Diagnosed intrathoracic meningocele is an uncommon complication of neurofibromatosis type 1. We report an anesthesia management for a rare case undergoing thoracoscopic resection of a huge intrathoracic meningocele.
    Case presentation: A 51-year-old woman was scheduled for thoracoscopic meningectomy under general anesthesia. We monitored intrathecal pressure during anesthesia to prevent a decrease in intrathecal pressure. During surgery, the intrathecal pressure occasionally increased by around 5 cmH
    Conclusions: The CSF pressure was fluctuated by procedures during thoracoscopic resection of a huge meningocele. A CSF pressure monitoring was useful to detect the sudden change of CSF pressure immediately, which can cause intracranial hemorrhage.
    Language English
    Publishing date 2024-02-19
    Publishing country Germany
    Document type Journal Article
    ISSN 2363-9024
    ISSN (online) 2363-9024
    DOI 10.1186/s40981-024-00697-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Equilibration rate constant, k

    Masui, Kenichi / Hagihira, Satoshi

    Journal of anesthesia

    2022  Volume 36, Issue 6, Page(s) 757–762

    Abstract: Effect-site concentration is widely used to determine drug dosage in anesthesia practice. To obtain effect-site concentration, a pharmacokinetic model with a corresponding equilibration rate constant between plasma and effect-site, ... ...

    Abstract Effect-site concentration is widely used to determine drug dosage in anesthesia practice. To obtain effect-site concentration, a pharmacokinetic model with a corresponding equilibration rate constant between plasma and effect-site, k
    MeSH term(s) Male ; Female ; Humans ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Models, Biological ; Benzodiazepines ; Hypnotics and Sedatives ; Anesthesia, General
    Chemical Substances remimazolam (7V4A8U16MB) ; Benzodiazepines (12794-10-4) ; Hypnotics and Sedatives
    Language English
    Publishing date 2022-08-26
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1107821-2
    ISSN 1438-8359 ; 0913-8668
    ISSN (online) 1438-8359
    ISSN 0913-8668
    DOI 10.1007/s00540-022-03099-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Interpretation of laboratory tests for prevention of the SARS-CoV-2 transmission

    Masui, Kenichi

    J. anesth

    Abstract: With the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), medical providers should take care to prevent the transmission of SARS-CoV-2 in hospitals including super-spreading. Understanding super-spreading would be useful to reduce ... ...

    Abstract With the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), medical providers should take care to prevent the transmission of SARS-CoV-2 in hospitals including super-spreading. Understanding super-spreading would be useful to reduce future transmission. Some publications have shown clusters of SARS-CoV-2 such as at choir practice and in hospitals. Aerosol can be considered as a primary transmission route. As SARS-CoV-2 stability in aerosol is similar to SARS-CoV-1 with the higher reproductive number of SARS-CoV-2 than SARS-CoV-1, another factor causes rapidly spread-out, e.g. a higher discharge ratio from infected people or a higher viral intake ratio to human body. A basic research suggests higher infectivity of SARS-CoV-2 in the nose than the peripheral lung. Universal masking would be important to prevent the exposure of SARS-CoV-2 droplet to uninfected people. To detect SARS-CoV-2 infection, laboratory tests such as reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assays are applied. Although sensitivity and specificity are provided for the ability of the test, positive or negative prediction values are useful to indicate the possiblity of infection or non-infection in clinical practice. We have to realize that the positive and negative prediction values depend on the sensitivity, specificity, and infection probability of the patient.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #915218
    Database COVID19

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  10. Article ; Online: Lateral position for difficult intubation in a patient with history of hemiglossectomy and flap reconstruction: a case report.

    Yokogawa, Fumiko / Oe, Katsunori / Hosokawa, Maiko / Masui, Kenichi

    JA clinical reports

    2022  Volume 8, Issue 1, Page(s) 16

    Abstract: Background: Reconstructive head and neck surgery can alter upper airway anatomy. We report a difficult intubation in a patient with a history of hemiglossectomy and reconstruction.: Case presentation: A 65-year-old female patient, who had undergone ... ...

    Abstract Background: Reconstructive head and neck surgery can alter upper airway anatomy. We report a difficult intubation in a patient with a history of hemiglossectomy and reconstruction.
    Case presentation: A 65-year-old female patient, who had undergone hemiglossectomy with the flap reconstruction, underwent video-assisted thoracoscopic esophagectomy for esophageal cancer. After the loss of consciousness during anesthesia induction, we failed to perform direct and oral fiberoptic intubation using a video laryngoscope and nasal fiberoptic intubation without or with video laryngoscope assistance in the supine position. Finally, shifting the patient to the left-lateral position allowed successful nasal fiberoptic intubation. Postoperatively, we were informed that she was unable to sleep in the supine position because of airway obstruction and therefore always slept on her side.
    Conclusion: Preanesthetic evaluation of the influence of body position on the airway patency during sleep or sedation may aid in airway management.
    Language English
    Publishing date 2022-03-03
    Publishing country Germany
    Document type Journal Article
    ISSN 2363-9024
    ISSN (online) 2363-9024
    DOI 10.1186/s40981-022-00509-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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