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  1. Article ; Online: Assessment of severity and prognosis in COPD: moving beyond percent of predicted.

    Culver, Bruce H

    The European respiratory journal

    2018  Volume 52, Issue 2

    MeSH term(s) Forced Expiratory Volume ; Humans ; Prognosis ; Pulmonary Disease, Chronic Obstructive
    Language English
    Publishing date 2018-08-02
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.01005-2018
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  2. Article ; Online: Quality Standards in Pulmonary Function Testing: Past, Present, Future.

    Wanger, Jack S / Culver, Bruce H

    Annals of the American Thoracic Society

    2016  Volume 13, Issue 9, Page(s) 1435–1436

    MeSH term(s) Forecasting ; Humans ; Reference Standards ; Respiratory Function Tests/standards
    Language English
    Publishing date 2016-09-13
    Publishing country United States
    Document type Editorial
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.201604-300ED
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  3. Article ; Online: Obstructive? Restrictive? Or a ventilatory impairment?

    Culver, Bruce H

    Chest

    2011  Volume 140, Issue 3, Page(s) 568–569

    MeSH term(s) Female ; Forced Expiratory Volume ; Humans ; Lung Diseases, Obstructive/physiopathology ; Male ; Severity of Illness Index
    Language English
    Publishing date 2011-09
    Publishing country United States
    Document type Comment ; Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1378/chest.11-0935
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  4. Article: How should the lower limit of the normal range be defined?

    Culver, Bruce H

    Respiratory care

    2012  Volume 57, Issue 1, Page(s) 136–45; discussion 143–5

    Abstract: Lung function parameters vary considerably with age and body size, so that, unlike many laboratory tests, the normal range of expected values must be individualized. For spirometry, only low values are considered to be abnormal, so the lower limit of ... ...

    Abstract Lung function parameters vary considerably with age and body size, so that, unlike many laboratory tests, the normal range of expected values must be individualized. For spirometry, only low values are considered to be abnormal, so the lower limit of normal (LLN) is taken to be equal to the 5th percentile of a healthy, non-smoking population. Simple and commonly used "rules of thumb," such as an FEV(1)/FVC < 0.70 to indicate air-flow obstruction, or assuming values < 80% of predicted to be abnormal, are inaccurate and will cause misclassification, specifically under-diagnosis of abnormalities in younger, taller individuals and over-diagnosis in those older or shorter. A much more accurate LLN for the FEV(1)/FVC ratio, which recognizes the change with age of this measurement, can be easily determined by subtracting 10 (10% or 0.10) from the age specific FEV(1)/FVC predicted for any individual. The analysis and mathematical descriptions of reference data have become increasingly sophisticated in recent years, but the interpretation of values near the LLN continues to carry uncertainty, due to an overlap in values between low normal values and those reflecting early disease. Among patients referred to a pulmonary function laboratory, the pre-test probability of disease may be relatively high, so that even individuals with values above the LLN may be more likely than not to have respiratory disease. A future goal for the pulmonary community would be the development of risk stratified outcome data that would allow an estimation of the probability of disease with progressive decrements in lung function. While interpreting spirometry results near the LLN will continue to be problematic, a more important task for the pulmonary community is to focus on finding the pool of individuals with clear-cut, but undiagnosed, COPD. And for this, good quality spirometry remains the best tool and must be widely available.
    MeSH term(s) Humans ; Lung Volume Measurements ; Nutrition Surveys ; Pulmonary Diffusing Capacity/standards ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Reference Values ; Risk Assessment ; Spirometry/standards
    Language English
    Publishing date 2012-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 603252-7
    ISSN 0020-1324 ; 0098-9142
    ISSN 0020-1324 ; 0098-9142
    DOI 10.4187/respcare.01427
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  5. Article: Interpretation of spirometry: we can do better than the GOLD standard.

    Culver, Bruce H

    Respiratory care

    2006  Volume 51, Issue 7, Page(s) 719–721

    MeSH term(s) Humans ; Predictive Value of Tests ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Respiratory Function Tests ; Sensitivity and Specificity ; Spirometry/standards
    Language English
    Publishing date 2006-07
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 603252-7
    ISSN 0020-1324 ; 0098-9142
    ISSN 0020-1324 ; 0098-9142
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  6. Article: International consensus on lung function testing during the COVID-19 pandemic and beyond.

    McGowan, Aisling / Laveneziana, Pierantonio / Bayat, Sam / Beydon, Nicole / Boros, P W / Burgos, Felip / Fležar, Matjaž / Franczuk, Monika / Galarza, Maria-Alejandra / Kendrick, Adrian H / Lombardi, Enrico / Makonga-Braaksma, Jellien / McCormack, Meredith C / Plantier, Laurent / Stanojevic, Sanja / Steenbruggen, Irene / Thompson, Bruce / Coates, Allan L / Wanger, Jack /
    Cockcroft, Donald W / Culver, Bruce / Sylvester, Karl / De Jongh, Frans

    ERJ open research

    2022  Volume 8, Issue 1

    Abstract: Coronavirus disease 2019 (COVID-19) has negatively affected the delivery of respiratory diagnostic services across the world due to the potential risk of disease transmission during lung function testing. Community prevalence, reoccurrence of COVID-19 ... ...

    Abstract Coronavirus disease 2019 (COVID-19) has negatively affected the delivery of respiratory diagnostic services across the world due to the potential risk of disease transmission during lung function testing. Community prevalence, reoccurrence of COVID-19 surges and the emergence of different variants of SARS-CoV-2 have impeded attempts to restore services. Finding consensus on how to deliver safe lung function services for both patients attending and for staff performing the tests are of paramount importance. This international statement presents the consensus opinion of 23 experts in the field of lung function and respiratory physiology balanced with evidence from the reviewed literature. It describes a robust roadmap for restoration and continuity of lung function testing services during the COVID-19 pandemic and beyond. Important strategies presented in this consensus statement relate to the patient journey when attending for lung function tests. We discuss appointment preparation, operational and environmental issues, testing room requirements including mitigation strategies for transmission risk, requirement for improved ventilation, maintaining physical distance and use of personal protection equipment. We also provide consensus opinion on precautions relating to specific tests, filters, management of special patient groups and alternative options to testing in hospitals. The pandemic has highlighted how vulnerable lung function services are and forces us to re-think how long-term mitigation strategies can protect our services during this and any possible future pandemic. This statement aspires to address the safety concerns that exist and provide strategies to make lung function tests and the testing environment safer when tests are required.
    Language English
    Publishing date 2022-03-07
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2827830-6
    ISSN 2312-0541
    ISSN 2312-0541
    DOI 10.1183/23120541.00602-2021
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  7. Article ; Online: Defining airflow obstruction.

    Quanjer, Philip H / Cooper, Brendan / Ruppel, Gregg L / Swanney, Maureen P / Stocks, Janet / Culver, Bruce H / Thompson, Bruce R

    The European respiratory journal

    2015  Volume 45, Issue 2, Page(s) 561–562

    MeSH term(s) Asthma/diagnosis ; Asthma/epidemiology ; Female ; Humans ; Male ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/epidemiology
    Language English
    Publishing date 2015-02
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/09031936.00126014
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    Zs.A 2322: Show issues Location:
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  8. Article ; Online: International consensus on lung function testing during the COVID-19 pandemic and beyond

    Aisling McGowan / Pierantonio Laveneziana / Sam Bayat / Nicole Beydon / P.W. Boros / Felip Burgos / Matjaž Fležar / Monika Franczuk / Maria-Alejandra Galarza / Adrian H. Kendrick / Enrico Lombardi / Jellien Makonga-Braaksma / Meredith C. McCormack / Laurent Plantier / Sanja Stanojevic / Irene Steenbruggen / Bruce Thompson / Allan L. Coates / Jack Wanger /
    Donald W. Cockcroft / Bruce Culver / Karl Sylvester / Frans De Jongh

    ERJ Open Research, Vol 8, Iss

    2022  Volume 1

    Abstract: Coronavirus disease 2019 (COVID-19) has negatively affected the delivery of respiratory diagnostic services across the world due to the potential risk of disease transmission during lung function testing. Community prevalence, reoccurrence of COVID-19 ... ...

    Abstract Coronavirus disease 2019 (COVID-19) has negatively affected the delivery of respiratory diagnostic services across the world due to the potential risk of disease transmission during lung function testing. Community prevalence, reoccurrence of COVID-19 surges and the emergence of different variants of SARS-CoV-2 have impeded attempts to restore services. Finding consensus on how to deliver safe lung function services for both patients attending and for staff performing the tests are of paramount importance. This international statement presents the consensus opinion of 23 experts in the field of lung function and respiratory physiology balanced with evidence from the reviewed literature. It describes a robust roadmap for restoration and continuity of lung function testing services during the COVID-19 pandemic and beyond. Important strategies presented in this consensus statement relate to the patient journey when attending for lung function tests. We discuss appointment preparation, operational and environmental issues, testing room requirements including mitigation strategies for transmission risk, requirement for improved ventilation, maintaining physical distance and use of personal protection equipment. We also provide consensus opinion on precautions relating to specific tests, filters, management of special patient groups and alternative options to testing in hospitals. The pandemic has highlighted how vulnerable lung function services are and forces us to re-think how long-term mitigation strategies can protect our services during this and any possible future pandemic. This statement aspires to address the safety concerns that exist and provide strategies to make lung function tests and the testing environment safer when tests are required.
    Keywords Medicine ; R
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher European Respiratory Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Reply to Johnson: Improve Pulmonary Function Test Reporting.

    Culver, Bruce H / Graham, Brian L / MacIntyre, Neil R / McCormack, Meredith / Kaminsky, David A / Coates, Allan L / Weiner, Daniel J / Rosenfeld, Margaret / Wanger, Jack

    American journal of respiratory and critical care medicine

    2018  Volume 198, Issue 1, Page(s) 138–139

    MeSH term(s) Respiratory Function Tests ; Societies ; United States
    Language English
    Publishing date 2018-03-12
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.201802-0280LE
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  10. Article ; Online: Degradation Mechanisms at the Li

    Zhang, Wenbo / Richter, Felix H / Culver, Sean P / Leichtweiss, Thomas / Lozano, Juan G / Dietrich, Christian / Bruce, Peter G / Zeier, Wolfgang G / Janek, Jürgen

    ACS applied materials & interfaces

    2018  Volume 10, Issue 26, Page(s) 22226–22236

    Abstract: All-solid-state batteries (ASSBs) show great potential for providing high power and energy densities with enhanced battery safety. While new solid electrolytes (SEs) have been developed with high enough ionic conductivities, SSBs with long operational ... ...

    Abstract All-solid-state batteries (ASSBs) show great potential for providing high power and energy densities with enhanced battery safety. While new solid electrolytes (SEs) have been developed with high enough ionic conductivities, SSBs with long operational life are still rarely reported. Therefore, on the way to high-performance and long-life ASSBs, a better understanding of the complex degradation mechanisms, occurring at the electrode/electrolyte interfaces is pivotal. While the lithium metal/solid electrolyte interface is receiving considerable attention due to the quest for high energy density, the interface between the active material and solid electrolyte particles within the composite cathode is arguably the most difficult to solve and study. In this work, multiple characterization methods are combined to better understand the processes that occur at the LiCoO
    Language English
    Publishing date 2018-07-05
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.8b05132
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