Article: Interspecies Communication between Pathogens and Immune Cells via Bacterial Membrane Vesicles.
Frontiers in cell and developmental biology
2016 Volume 4, Page(s) 125
Abstract: The production of extracellular vesicles is a universal mechanism for intercellular communication that is conserved across kingdoms. Prokaryotes secrete 50-250 nm membrane vesicles (MVs) in a manner that is regulated by environmental stress and is ... ...
| Abstract | The production of extracellular vesicles is a universal mechanism for intercellular communication that is conserved across kingdoms. Prokaryotes secrete 50-250 nm membrane vesicles (MVs) in a manner that is regulated by environmental stress and is thought to promote survival. Since many types of host-derived stress are encountered during infection, this implies an important role for MV secretion in bacterial pathogenesis. Accordingly, MVs produced by gram-positive and gram-negative pathogens contain toxins, virulence factors, and other molecules that promote survival in the host. However, recent studies have also shown that bacterial MVs are enriched for molecules that stimulate innate and adaptive immune responses. As an example, MVs may serve multiple, important roles in regulating the host response to |
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| Language | English |
| Publishing date | 2016-11-11 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 2737824-X |
| ISSN | 2296-634X |
| ISSN | 2296-634X |
| DOI | 10.3389/fcell.2016.00125 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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