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  1. AU=Lu Chen Chen
  2. AU="Shabsovich, David"
  3. AU="Foraker, Randi E"
  4. AU="Kolonko, Aureliusz"
  5. AU=Falagas M E
  6. AU="Dunstan, Melanie L"
  7. AU=Kacar Mark AU=Kacar Mark
  8. AU="Schaup, Rebecca Michaela"
  9. AU="Ye, Chaofu"
  10. AU="Tekin, Nur"
  11. AU="Martens, Dirk E"
  12. AU=Teos Leyla Y.
  13. AU="Sánchez-Garcia, Joaquín"
  14. AU="Schaller, Benoit"
  15. AU="Hernandez, A"
  16. AU="Nguyen, Thien H"
  17. AU="Park, Jung Wan"
  18. AU="Mahajan, Aman"
  19. AU="Hao, Yanling"
  20. AU="Eing, Lorenz"
  21. AU="Geoffroy, Pierre A"
  22. AU="Chapuis, J"
  23. AU="Berta, László"
  24. AU="Barzilay, Regina"
  25. AU="Schmidt, Michael Rahbek"
  26. AU=Tack J
  27. AU="Oh, Hye Min"
  28. AU=Gaffen Sarah L AU=Gaffen Sarah L
  29. AU="Schmitt, Christine"
  30. AU="McKay, Jackie"
  31. AU="Bellissimo, Catherine A"
  32. AU="Desai, Urja"
  33. AU="Chini, Maria Giovanna"
  34. AU="Xiao, Difei"
  35. AU="Ryan, Chris"
  36. AU="Omar Bazighifan"
  37. AU="Corominas Galbany, Jordi"
  38. AU=Fox Norma E
  39. AU="Hamilton, Shelia M"
  40. AU="Nichols, J Wylie"
  41. AU="Pesce R."
  42. AU="Gambitta, P"
  43. AU="Imran, Aqeel"
  44. AU="Sharma, Yashoda"
  45. AU="Kosai, Jordyn"
  46. AU="Aroca Ferri, María"
  47. AU="Laba, Stephanie"
  48. AU="Kim, Ye-Sel"

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  1. Artikel ; Online: Correction: Chen et al. Secondary Metabolites with Anti-Inflammatory from the Roots of

    Chen, Jih-Jung / Cheng, Ming-Jen / Lee, Tzong-Huei / Kuo, Yueh-Hsiung / Lu, Chao-Tsen

    Molecules (Basel, Switzerland)

    2022  Band 27, Heft 18

    Abstract: The authors wish to make the following changes to their paper [ ... ]. ...

    Abstract The authors wish to make the following changes to their paper [...].
    Sprache Englisch
    Erscheinungsdatum 2022-09-16
    Erscheinungsland Switzerland
    Dokumenttyp Published Erratum
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27186035
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  2. Artikel ; Online: Correction: Chen et al. Upconversion Fluorescence Nanoprobe-Based FRET for the Sensitive Determination of

    Chen, Min / Yan, Zhongyu / Han, Lu / Zhou, Dandan / Wang, Yan / Pan, Leiqing / Tu, Kang

    Biosensors

    2023  Band 13, Heft 7

    Abstract: In the original publication, there is a mistake in Figure 1: A duplication error between 1B and 1C, which occurred due to the similarity of the images of the three nanoparticles [ ... ]. ...

    Abstract In the original publication, there is a mistake in Figure 1: A duplication error between 1B and 1C, which occurred due to the similarity of the images of the three nanoparticles [...].
    Sprache Englisch
    Erscheinungsdatum 2023-07-07
    Erscheinungsland Switzerland
    Dokumenttyp Published Erratum
    ZDB-ID 2662125-3
    ISSN 2079-6374 ; 2079-6374
    ISSN (online) 2079-6374
    ISSN 2079-6374
    DOI 10.3390/bios13070713
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Professor Chen Xianhai's experience of herb pairs in the treatment of pulmonary diseases

    Jia-Lu Ma / Xian-Hai Chen

    Journal of Hainan Medical University, Vol 27, Iss 12, Pp 49-

    2021  Band 50

    Abstract: ... Chen combined with the theory of traditional Chinese medicine and constitution identification ...

    Abstract According to the theory of traditional Chinese medicine, based on the four properties and five flavors of traditional Chinese medicines, the lifting and lowering theory and channel tropism, Professor Chen combined with the theory of traditional Chinese medicine and constitution identification to prescribe for patients and used herb pairs to treat many kinds of pulmonary diseases. And he has achieved good clinical effect by "treatment methods selection according to syndromes". His experience in medication and compatibility mechanism are worthy of further exploration and promotion by scholars.
    Schlagwörter herb pairs ; pulmonary diseases ; syndrome differentiation and treatment ; experience ; chen xian-hai ; Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2021-06-01T00:00:00Z
    Verlag Editorial Board of Journal of Hainan Medical University
    Dokumenttyp Artikel ; Online
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  4. Artikel ; Online: Network pharmacology reveals the targets and mechanism for Panax notoginseng (Burk.) F. H. Chen against venous thromboembolism

    Weili Feng / Anqi Lu / Daoqiang Huang / Chunyu Jiang / Bingze Chen / Xiaoping Wang

    Pharmacological Research - Modern Chinese Medicine, Vol 2, Iss , Pp 100035- (2022)

    2022  

    Abstract: Background: Panax notoginseng (Burk.) F. H. Chen (PN) is an integral part ...

    Abstract Background: Panax notoginseng (Burk.) F. H. Chen (PN) is an integral part of traditional Chinese medicine (TCM) that has been extensively applied to prevent and treat blood stasis for hundreds of years, whereas the inhibitory mechanism of PN against venous thromboembolism (VTE) has remained a mystery. Objective: This study aimed to reveal the prophylactic effect and illuminate the possible mechanism of PN on venous thromboembolism. Methods: The Traditional Chinese Medicine Database and Analysis Platform (TCMSP) were utilized to search and screen for potent ingredients of PN as well as to analyze potential prophylactic and therapeutic targets against VTE. On the contrary, four disease databases were excavated to collect VTE-related genes. Common targets were obtained by integrating the gene expression profile of VTE and chemical-protein data of PN. A protein-protein interaction (PPI) network was constructed to demonstrate interactions among gene products. GO function, KEGG pathway, and topology analyses were performed to depict functional and dimensional characteristics of contributing targets. Results: Network pharmacology indicated that vascular smooth muscle contraction, platelet activation, and complement and coagulation cascades were the main pathways involved in the prophylactic and therapeutic effect of PN against VTE. MAPK1, SP1, RB1, and TP53 are the main genes related to the anticoagulation effect of PN. Injection, spray, or other preparations may be more suitable than direct oral administration of PN. Conclusion: PN can exert its anticoagulation effect to prevent and treat VTE, which is probably attributable to modulating coagulation cascades. This helps estimate the therapeutic effect of PN on VTE and leads to an increase in the numbers of PN-related researches.
    Schlagwörter Network pharmacology ; Panax notoginseng ; Venous thromboembolism ; Deep venous thrombosis ; Other systems of medicine ; RZ201-999 ; Therapeutics. Pharmacology ; RM1-950
    Sprache Englisch
    Erscheinungsdatum 2022-03-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: Anti-inflammatory flavonoid derivatives from the heartwood of Dalbergia odorifera T. Chen

    Zan, Ni-li / Lu, Zi-Han / Wang, Xin-Yu / Wang, Rong-Ye / Liang, Nai-Yun / Huo, Hui-Xia / Zhao, Yun-Fang / Song, Yue-Lin / Tu, Peng-Fei / Zheng, Jiao / Li, Jun

    Natural Product Research. 2023 Mar. 19, v. 37, no. 6 p.928-935

    2023  

    Abstract: ... isolated from the heartwood of Dalbergia odorifera T. Chen. Their structures were elucidated by extensive ...

    Abstract Two pairs of flavonoid enantiomers (1a/1b and 2a/2b) together with three known analogues (3–5) were isolated from the heartwood of Dalbergia odorifera T. Chen. Their structures were elucidated by extensive spectroscopic analysis (1 D and 2 D NMR, UV, IR, and HRMS) and experimental and calculated ECD data. Compound 2 features an unusual 2-methyl-3(2H)-furanone moiety forming the C-ring of flavonoid, and its putative biosynthetic pathway is also proposed. Compounds 3‒5 exhibited significant inhibition of nitric oxide production in lipopolysaccharide-stimulated RAW264.7 cells with IC₅₀ values of 14.7 ± 0.3 μM, 40.2 ± 1.1 μM, and 3.2 ± 0.1 μM, respectively.
    Schlagwörter Dalbergia odorifera ; biochemical pathways ; enantiomers ; flavonoids ; heartwood ; moieties ; nitric oxide ; research ; spectral analysis ; Dalbergia odorifera T. Chen ; flavonoid derivative ; GIAO NMR calculation ; anti-inflammation
    Sprache Englisch
    Erscheinungsverlauf 2023-0319
    Umfang p. 928-935.
    Erscheinungsort Taylor & Francis
    Dokumenttyp Artikel ; Online
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2022.2098494
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  6. Artikel ; Online: Predicting potential distribution of Ziziphus spinosa (Bunge) H.H. Hu ex F.H. Chen in China under climate change scenarios

    Qian Zhao / Ze‐Yuan Mi / Chan Lu / Xin‐Fei Zhang / Li‐Jun Chen / Shi‐Qiang Wang / Jun‐Feng Niu / Zhe‐Zhi Wang

    Ecology and Evolution, Vol 12, Iss 2, Pp n/a-n/a (2022)

    2022  

    Abstract: Abstract Ziziphus spinosa (Bunge) H.H. Hu ex F.H. Chen is a woody plant species of the family ...

    Abstract Abstract Ziziphus spinosa (Bunge) H.H. Hu ex F.H. Chen is a woody plant species of the family Rhamnaceae (order Rhamnales) that possesses high nutritional and medicinal value. Predicting the effects of climate change on the distribution of Z. spinosa is of great significance for the investigation, protection, and exploitation of this germplasm resource. For this study, optimized maximum entropy models were employed to predict the distribution patterns and changes of its present (1970–2000) and future (2050s, 2070s, and 2090s) potential suitable regions in China under multiple climate scenarios (SSP1‐2.6, SSP2‐4.5, SSP3‐7.0 & SSP5‐8.5). The results revealed that the total area of the present potential suitable region for Z. spinosa is 162.60 × 104 km2, which accounts for 16.94% of China's territory. Within this area, the regions having low, medium, and high suitability were 80.14 × 104 km2, 81.50 × 104 km2, and 0.96 × 104 km2, respectively, with the high suitability regions being distributed primarily in Shanxi, Hebei, and Beijing Provinces. Except for SSP‐1‐2.6‐2070s, SSP‐5‐8.5‐2070s, and SSP‐5‐8.5‐2090s, the suitable areas for Z. spinosa in the future increased to different degrees. Meanwhile, considering the distribution of Z. spinosa during different periods and under different climate scenarios, our study predicted that the low impact areas of Z. spinosa were mainly restricted to Shanxi, Shaanxi, Ningxia, Gansu, Liaoning, Inner Mongolia, and Jilin Provinces. The results of core distributional shifts showed that, except for SSP1‐2.6, the center of the potential suitable region of Z. spinosa exhibited a trend of gradually shifting to the northwest.
    Schlagwörter ecological niche modeling ; maximum entropy ; prediction of suitable region ; Ziziphus spinosa (Bunge) H.H. Hu ex F.H. Chen ; Ecology ; QH540-549.5
    Thema/Rubrik (Code) 550
    Sprache Englisch
    Erscheinungsdatum 2022-02-01T00:00:00Z
    Verlag Wiley
    Dokumenttyp Artikel ; Online
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  7. Artikel: Comparative transcriptome analysis of Locusta migratoria tibetensis Chen (Orthoptera: Oedipodidae) under high‐ and low‐temperature stress

    Ran, Lu‐yao / Jiang, Chun‐xian / Yang, Qun‐fang / Wang, Hai‐jian / Bai ma, Tun‐zhu / Chen, Li / Kuang, Jian‐kang / Huang, Ting‐ting / Li, Qing

    Journal of applied entomology. 2020 Apr., v. 144, no. 3

    2020  

    Abstract: The endemic locust species on the Tibetan plateau, Locusta migratoria tibetensis Chen can grow and ...

    Abstract The endemic locust species on the Tibetan plateau, Locusta migratoria tibetensis Chen can grow and breed successfully under the plateau temperature environment. This study explored the molecular response process of Tibetan locusts to high and low temperatures by comparing its transcriptome under different temperature conditions. A total of 66,256 unigenes were obtained through RNA‐Seq, among which 30,051 were successfully annotated. In detail, there were 778 differentially expressed genes (DEGs) at high temperatures and 1,787 DEGs at low temperatures. Under high temperatures, the metabolic pathways of saturated and unsaturated fatty acids and amino acids were up‐regulated, producing a significant amount of fatty acids and amino acids. However, under low temperatures, the chitinase activity was enhanced, causing chitin to decompose into small sugar molecules. Meanwhile, various sugar metabolism pathways were up‐regulated when a significant amount of small sugar molecules were produced. Then, large quantities of alpha‐linolenic acid and arachidonic acid were accumulated to maintain the normal physiological functions of cells. The analysis of annotated genes revealed that heat shock proteins (Hsp) were associated with the response to temperature stress, and mainly involved in the synthesis and transportation of proteins, preventing protein damage and the decomposition of damaged proteins. These results provide a basis for the further understanding of the adaptation mechanism of Tibetan locusts to high and low temperatures, laying a foundation for further understanding the adaptability of Tibetan locusts on Tibetan plateaus.
    Schlagwörter Locusta migratoria ; alpha-linolenic acid ; arachidonic acid ; chitin ; chitinase ; cold stress ; entomology ; gene expression regulation ; heat stress ; metabolism ; sequence analysis ; sugars ; temperature ; transcriptome ; transcriptomics ; transportation ; unigenes ; China
    Sprache Englisch
    Erscheinungsverlauf 2020-04
    Umfang p. 181-190.
    Erscheinungsort John Wiley & Sons, Ltd
    Dokumenttyp Artikel
    Anmerkung NAL-AP-2-clean ; JOURNAL ARTICLE
    ZDB-ID 631360-7
    ISSN 1439-0418 ; 0044-2240 ; 0931-2048
    ISSN (online) 1439-0418
    ISSN 0044-2240 ; 0931-2048
    DOI 10.1111/jen.12728
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  8. Artikel ; Online: Response by Lu and Chen to Letter Regarding Article, "Acupuncture Therapy and Incidence of Depression After Stroke".

    Lu, Chung-Yen / Chen, Pei-Chun

    Stroke

    2017  Band 48, Heft 8, Seite(n) e232

    Sprache Englisch
    Erscheinungsdatum 2017-08
    Erscheinungsland United States
    Dokumenttyp Letter
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.117.017925
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  9. Artikel: Production of allohexaploid Brassica hybrid between tuber mustard (Brassica juncea L. var. crassicaulis Chen &Yang) and Chinese kale (Brassica oleracea var. alboglabra Bailey)

    Chen, Fangfang / Zhu, Zhiyu / Tong, Lu / Guo, Xiaocan / Xu, Shenglong / Chen, Jiahong / Wu, Jianguo / Zhu, Zhujun

    Scientia horticulturae. 2020 Aug. 25, v. 270

    2020  

    Abstract: ... between inbred lines of tuber mustard (Brassica juncea var. crassicaulis Chen &Yang; AABB) and ...

    Abstract Brassica is a key agricultural genus, containing oilseed and vegetable crops, which includes three major genomes (A, B and C), distributed in diploid (genomes: AA, BB and CC) and allotetraploid species (genomes: AABB, AACC and BBCC). Interspecific hybridization between Brassica species is an important way to combine valuable characters from the different species. In the present study, distant hybridization between inbred lines of tuber mustard (Brassica juncea var. crassicaulis Chen &Yang; AABB) and Chinese kale (Brassica oleracea var. alboglabra Bailey; CC) was conducted and allotriploid interspecific hybrids were identified. The hybrid seed set was improved by gibberellin treatment of the stigmas prior to pollination. Eight hybrid seedlings were obtained by bud pollination and ovary culture, and all seedlings were confirmed to be true hybrids by phenotypic analysis, cytological observation (27 chromosomes) and the use of parent-specific randomly amplified polymorphic DNA (RAPD) molecular markers. After tissue culture and colchicine-induced chromosome-doubling treatment, allohexaploid hybrids (AABBCC) were isolated and identified from the eight hybrids. The chromosomes of five plants were completely doubled, with a doubling rate of 5.68 %, and the number of chimeric plants was 24, at a rate of 27.27 %, when roots were immersed in 0.1 % colchicine solution. In comparison with the allotriploid hybrid, the synthetic hexaploid hybrids showed unique phenotypes with normal anthers, well-developed pods, larger flowers and petals, thicker stems than either parent and other phenotype types intermediate between the two parents. In the present study, synthetic tri-genomic Brassica vegetable germplasm, combining the A, B and C genomes, was created for use in vegetable breeding, as well as for a basis for further investigation of the mechanisms of Brassica evolution and adaptation. The current study is of great significance for the use of these allohexaploid plants to explore the heterotic effects of distant hybridization and for genetic improvement.
    Schlagwörter Brassica juncea ; Brassica oleracea var. alboglabra ; DNA ; allotetraploidy ; colchicine ; diploidy ; evolution ; genetic improvement ; genome ; germplasm ; gibberellins ; heterosis ; hexaploidy ; hybrids ; interspecific hybridization ; oilseeds ; phenotype ; pollination ; seed set ; tissue culture ; vegetables
    Sprache Englisch
    Erscheinungsverlauf 2020-0825
    Erscheinungsort Elsevier B.V.
    Dokumenttyp Artikel
    Anmerkung NAL-AP-2-clean
    ZDB-ID 185557-8
    ISSN 0304-4238
    ISSN 0304-4238
    DOI 10.1016/j.scienta.2020.109412
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  10. Artikel: Reply to: Correspondence Regarding the Study by Chen-Lu Yang et al. Published in the Chinese Medical Journal, 129(18):2258-9.

    Yang, Chen-Lu / Shen, Kai / Xie, Qi-Bing / Yin, Geng

    Chinese medical journal

    2016  Band 129, Heft 23, Seite(n) 2898

    Mesh-Begriff(e) Asian Continental Ancestry Group ; Bibliometrics ; China ; Humans ; Medicine, Chinese Traditional ; Periodicals as Topic ; Publications
    Sprache Englisch
    Erscheinungsdatum 2016--05
    Erscheinungsland China
    Dokumenttyp Letter ; Comment
    ZDB-ID 127089-8
    ISSN 0366-6999 ; 1002-0187
    ISSN 0366-6999 ; 1002-0187
    DOI 10.4103/0366-6999.194652
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