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  1. Article ; Online: Speech-Language Pathologists' Endorsement of Speech, Language, and Literacy Myths Reveals Persistent Research-Practice Gap.

    McDaniel, Jena / Krimm, Hannah / Schuele, C Melanie

    Language, speech, and hearing services in schools

    2023  Volume 54, Issue 2, Page(s) 550–568

    Abstract: Purpose: We explore the extent to which speech-language pathologists (SLPs) are operating under assumptions about speech, language, and literacy that are not supported by evidence or are contradicted by evidence.: Method: SLPs (: Results: Based on ...

    Abstract Purpose: We explore the extent to which speech-language pathologists (SLPs) are operating under assumptions about speech, language, and literacy that are not supported by evidence or are contradicted by evidence.
    Method: SLPs (
    Results: Based on results of one-sample
    Conclusions: The findings indicate areas of relative strength for SLPs' knowledge of current evidence for augmentative and alternative communication, bilingualism, and language input that supports language development. Identified areas of relative weakness include knowledge of the expected grammatical and speech production skills of children with typical development and the influence of ear infections in childhood on language impairment. Additional research is needed to evaluate efforts to enhance SLPs' knowledge and use of evidence-based practices.
    MeSH term(s) Child ; Humans ; Speech ; Literacy ; Professional Practice Gaps ; Pathologists ; Communication Disorders ; Surveys and Questionnaires ; Speech-Language Pathology
    Language English
    Publishing date 2023-02-17
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2067619-0
    ISSN 1558-9129 ; 0161-1461
    ISSN (online) 1558-9129
    ISSN 0161-1461
    DOI 10.1044/2022_LSHSS-22-00087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Conceptions and Misconceptions: What Do School-Based Speech-Language Pathologists Think About Dyslexia?

    Krimm, Hannah / McDaniel, Jena / Schuele, C Melanie

    Language, speech, and hearing services in schools

    2023  Volume 54, Issue 4, Page(s) 1267–1281

    Abstract: Purpose: The purpose of this exploratory study was to evaluate speech-language pathologists' (SLPs') conceptions and misconceptions about dyslexia.: Method: Participants were 86 school-based SLPs. They completed an online survey on which they rated ... ...

    Abstract Purpose: The purpose of this exploratory study was to evaluate speech-language pathologists' (SLPs') conceptions and misconceptions about dyslexia.
    Method: Participants were 86 school-based SLPs. They completed an online survey on which they rated their agreement and disagreement with true and false statements related to the scientific evidence about the nature of dyslexia and interventions for dyslexia, as well as common misconceptions about dyslexia.
    Results: There was considerable variability among SLPs' agreement and disagreement with the statements. Critically, despite abundant contrary evidence in the literature, many SLPs believe that dyslexia involves a visual processing deficit.
    Conclusions: These findings suggest that many school-based SLPs hold misconceptions about dyslexia, especially those related to dyslexia being a visual disorder. The identified misconceptions may contribute to some SLPs' reluctance to incorporate reading and prereading skills into speech-language assessment and intervention. SLPs need greater knowledge of dyslexia to provide more effective evaluations and intervention services.
    MeSH term(s) Humans ; Speech ; Pathologists ; Dyslexia/diagnosis ; Dyslexia/therapy ; Communication Disorders ; Speech Therapy ; Surveys and Questionnaires ; Speech-Language Pathology
    Language English
    Publishing date 2023-09-06
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2067619-0
    ISSN 1558-9129 ; 0161-1461
    ISSN (online) 1558-9129
    ISSN 0161-1461
    DOI 10.1044/2023_LSHSS-22-00199
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: SLPs' perceptions of language learning myths about children who are DHH.

    McDaniel, Jena / Krimm, Hannah / Schuele, C Melanie

    Journal of deaf studies and deaf education

    2023  Volume 29, Issue 2, Page(s) 245–257

    Abstract: This article reports on speech-language pathologists' (SLPs') knowledge related to myths about spoken language learning of children who are deaf and hard of hearing (DHH). The broader study was designed as a step toward narrowing the research-practice ... ...

    Abstract This article reports on speech-language pathologists' (SLPs') knowledge related to myths about spoken language learning of children who are deaf and hard of hearing (DHH). The broader study was designed as a step toward narrowing the research-practice gap and providing effective, evidence-based language services to children. In the broader study, SLPs (n = 106) reported their agreement/disagreement with myth statements and true statements (n = 52) about 7 clinical topics related to speech and language development. For the current report, participant responses to 7 statements within the DHH topic were analyzed. Participants exhibited a relative strength in bilingualism knowledge for spoken languages and a relative weakness in audiovisual integration knowledge. Much individual variation was observed. Participants' responses were more likely to align with current evidence about bilingualism if the participants had less experience as an SLP. The findings provide guidance on prioritizing topics for speech-language pathology preservice and professional development.
    MeSH term(s) Child ; Humans ; Language Development ; Hearing Loss ; Speech ; Learning ; Communication Disorders ; Surveys and Questionnaires
    Language English
    Publishing date 2023-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1494621-X
    ISSN 1465-7325 ; 1081-4159
    ISSN (online) 1465-7325
    ISSN 1081-4159
    DOI 10.1093/deafed/enad043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A machine learning model to predict therapeutic inertia in type 2 diabetes using electronic health record data.

    McDaniel, C C / Lo-Ciganic, W-H / Huang, J / Chou, C

    Journal of endocrinological investigation

    2023  

    Abstract: ... the discriminative ability (represented by C-statistics) between models.: Results: The cohort included 31,087 ... The therapeutic inertia prevalence was 39.80% among the 68,445 records. GBM outperformed (C-statistic from testing ... sample = 0.84, 95% CI = 0.83-0.84) RF (C-statistic = 0.80, 95% CI = 0.79-0.80), EN (C-statistic = 0.80 ...

    Abstract Objective: To estimate the therapeutic inertia prevalence for patients with type 2 diabetes, develop and validate a machine learning model predicting therapeutic inertia, and determine the added predictive value of area-level social determinants of health (SDOH).
    Methods: This prognostic study with a retrospective cohort design used OneFlorida data (linked electronic health records (EHRs) from 1240 practices/clinics in Florida). The study cohort included adults (aged ≥ 18) with type 2 diabetes, HbA1C ≥ 7% (53 mmol/mol), ≥one ambulatory visit, and ≥one antihyperglycemic medication prescribed (excluded patients prescribed insulin before HbA1C). The outcome was therapeutic inertia, defined as absence of treatment intensification within six months after HbA1C ≥ 7% (53 mmol/mol). The predictors were patient, provider, and healthcare system factors. Machine learning methods included gradient boosting machines (GBM), random forests (RF), elastic net (EN), and least absolute shrinkage and selection operator (LASSO). The DeLong test compared the discriminative ability (represented by C-statistics) between models.
    Results: The cohort included 31,087 patients with type 2 diabetes (mean age = 58.89 (SD = 13.27) years, 50.50% male, 58.89% White). The therapeutic inertia prevalence was 39.80% among the 68,445 records. GBM outperformed (C-statistic from testing sample = 0.84, 95% CI = 0.83-0.84) RF (C-statistic = 0.80, 95% CI = 0.79-0.80), EN (C-statistic = 0.80, 95% CI = 0.80-0.81), and LASSO (C-statistic = 0.80, 95% CI = 0.80-0.81), p < 0.05. Area-level SDOH significantly increased the discriminative ability versus models without SDOH (C-statistic for GBM = 0.84, 95% CI = 0.84-0.85 vs. 0.84, 95% CI = 0.83-0.84), p < 0.05.
    Conclusions: Using EHRs of patients with type 2 diabetes from a large state, machine learning predicted therapeutic inertia (prevalence = 40%). The model's ability to predict patients at high risk of therapeutic inertia is clinically applicable to diabetes care.
    Language English
    Publishing date 2023-12-31
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 432272-1
    ISSN 1720-8386 ; 0391-4097 ; 1121-1369
    ISSN (online) 1720-8386
    ISSN 0391-4097 ; 1121-1369
    DOI 10.1007/s40618-023-02259-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The role of H-H interactions and impurities on the structure and energetics of H/Pd(111).

    Thürmer, K / Bartelt, N C / Whaley, J A / McDaniel, A H / El Gabaly, F

    The Journal of chemical physics

    2022  Volume 156, Issue 4, Page(s) 44707

    Abstract: ... that H-H and H-Pd interactions promote the formation of the well-known 3×3 phases but also favor ... an unreported (3 × 3) phase at high H coverages for which we present experimental evidence. We relate ... the stability of isolated H vacancies of the (3 × 3) phase to the need of H ...

    Abstract Understanding hydrogen incorporation into palladium requires detailed knowledge of surface and subsurface structure and atomic interactions as surface hydrogen is being embedded. Using density functional theory (DFT), we examine the energies of hydrogen layers of varying coverage adsorbed on Pd(111). We find that H-H and H-Pd interactions promote the formation of the well-known 3×3 phases but also favor an unreported (3 × 3) phase at high H coverages for which we present experimental evidence. We relate the stability of isolated H vacancies of the (3 × 3) phase to the need of H
    Language English
    Publishing date 2022-02-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0068291
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  6. Article ; Online: Effects of supplementing milk replacer with essential amino acids on blood metabolites, immune response, and nitrogen metabolism of Holstein calves exposed to an endotoxin.

    Zubia, K M / Akter, A / Carter, B H / McDaniel, M R / Duff, G C / Löest, C A

    Journal of dairy science

    2023  Volume 106, Issue 8, Page(s) 5402–5415

    Abstract: ... without LPS (+LPS vs. -LPS) at 3 h after the morning feeding on d 15 (4 µg LPS per kg of BW) and 17 (2 µg LPS ... at h 4, 8, 12, and 24 thereafter. From d 15 to 19, total fecal and urinary output were collected, and ... feed refusals were documented. Rectal temperature was greater in +LPS than -LPS calves at h 4, 8, and ...

    Abstract This study evaluated the effects of supplementing calf milk replacer with essential AA on immune responses, blood metabolites, and nitrogen metabolism of 32 Holstein bull calves [28 d of age, 44 ± 0.8 kg of body weight (BW)] exposed to lipopolysaccharide (LPS). Calves were bottle-fed a commercial milk replacer (20% crude protein and 20% fat, dry matter basis) twice daily along with a calf starter (19% crude protein, dry matter basis) for 45 d. The experiment was a randomized complete block design and treatments were a 2 × 2 factorial arrangement. Treatments were milk replacer (fed twice daily at 0.5 kg/d of powder) supplemented with or without 10 essential AA (+AA vs. -AA), and subcutaneous injection of sterile saline with or without LPS (+LPS vs. -LPS) at 3 h after the morning feeding on d 15 (4 µg LPS per kg of BW) and 17 (2 µg LPS per kg of BW). Calves also received a 2-mL subcutaneous injection of ovalbumin (6 mg of ovalbumin/mL) on d 16 and 30. Rectal temperature and blood samples were collected on d 15 before LPS injection and at h 4, 8, 12, and 24 thereafter. From d 15 to 19, total fecal and urinary output were collected, and feed refusals were documented. Rectal temperature was greater in +LPS than -LPS calves at h 4, 8, and 12 after LPS injection. Serum cortisol was greater for +LPS than -LPS at h 4 after LPS exposure. At d 28, serum antiovalbumin IgG level was greater in +LPS +AA calves compared with +LPS -AA. Serum glucose was lower for +LPS than -LPS at h 4 and 8. Serum insulin was greater in +LPS than -LPS calves. Plasma concentrations of Thr, Gly, Asn, Ser, and hydroxyproline were lower for +LPS versus -LPS calves. Plasma concentrations of Met, Leu, Phe, His, Ile, Trp, Thr, and Orn were greater in +AA calves than -AA calves. Plasma urea N and N retention were not different among LPS and AA treatments. The lower concentrations of AA in +LPS than -LPS calves indicate higher demand for AA in immuno-compromised calves fed milk replacer. Additionally, higher concentration of ovalbumin-specific IgG level in +LPS calves supplemented with +AA compared with +LPS calves with -AA suggests that supplementing AA to immune-compromised calves might improve immune status.
    MeSH term(s) Animals ; Cattle ; Male ; Diet/veterinary ; Milk/metabolism ; Amino Acids, Essential ; Endotoxins ; Lipopolysaccharides ; Ovalbumin ; Body Weight ; Immunity ; Immunoglobulin G ; Nitrogen/metabolism ; Animal Feed/analysis ; Weaning
    Chemical Substances Amino Acids, Essential ; Endotoxins ; Lipopolysaccharides ; Ovalbumin (9006-59-1) ; Immunoglobulin G ; Nitrogen (N762921K75)
    Language English
    Publishing date 2023-06-16
    Publishing country United States
    Document type Randomized Controlled Trial, Veterinary ; Journal Article
    ZDB-ID 242499-x
    ISSN 1525-3198 ; 0022-0302
    ISSN (online) 1525-3198
    ISSN 0022-0302
    DOI 10.3168/jds.2022-22708
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: "Glow ELISA": sensitive immunoassay with minimal equipment and stable reagents.

    Vu, Binh V / Brosamer, Kristen / McDaniel, Naiyah / Kourentzi, Katerina / Willson, Richard C / Fernando, Harshica

    The Analyst

    2023  Volume 148, Issue 22, Page(s) 5582–5587

    Abstract: Glow enzyme-linked immunosorbent assay (glow ELISA) uses inexpensive and shelf-stable glow stick reagents to chemically excite fluorescent reporters, obviating the need for excitation light sources, filters, and complex optics. It achieves excellent ... ...

    Abstract Glow enzyme-linked immunosorbent assay (glow ELISA) uses inexpensive and shelf-stable glow stick reagents to chemically excite fluorescent reporters, obviating the need for excitation light sources, filters, and complex optics. It achieves excellent limits of detection while offering portability and equipment cost comparable to lateral flow immunoassays.
    MeSH term(s) Indicators and Reagents ; Enzyme-Linked Immunosorbent Assay ; Immunoassay
    Chemical Substances Indicators and Reagents
    Language English
    Publishing date 2023-11-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 210747-8
    ISSN 1364-5528 ; 0003-2654
    ISSN (online) 1364-5528
    ISSN 0003-2654
    DOI 10.1039/d3an01623d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Rapid screening of high-priority N-nitrosamines in pharmaceutical, forensic, and environmental samples with paper spray ionization and filter cone spray ionization-mass spectrometry.

    McDaniel, Trevor J / Holtz, Jessica M / Bondzie, Ebenezer H / Overfelt, Makoy / Fedick, Patrick W / Mulligan, Christopher C

    Rapid communications in mass spectrometry : RCM

    2023  Volume 37 Suppl 1, Page(s) e9493

    Abstract: Rationale: The burgeoning concern of N-nitrosamine (NAM) contamination found in various pharmaceutical compositions has increased the demand for rapid and reliable screening methods to better assess the breadth of the problem. These carcinogenic ... ...

    Abstract Rationale: The burgeoning concern of N-nitrosamine (NAM) contamination found in various pharmaceutical compositions has increased the demand for rapid and reliable screening methods to better assess the breadth of the problem. These carcinogenic compounds are also found in food, water, and soil, and they have been used in poison-related homicides.
    Methods: A combination of complementary, ambient ionization methods, paper spray ionization (PSI) and filter cone spray ionization (FCSI)-mass spectrometry (MS), was characterized towards trace-level residue screening of select NAMs (e.g., N-nitrosodimethylamine, N-nitrosodiethylamine, N-nitrosodibutylamine) directly from complex and problematic matrices of interest, including prescription and over-the-counter tablets, drinking water, soil, and consumable goods. Spectral data for analyte confirmation and detection limit studies were collected using a Thermo LCQ Fleet ion trap mass spectrometer.
    Results: PSI-MS and FCSI-MS readily produced mass spectral data marked by their simplicity (e.g., predominantly protonated molecular ions observed) and congruence with traditional electrospray ionization mass spectra in under 2 min. per sample. Both methods proved robust to the complex matrices tested, yielding ion signatures for target NAMs, as well as active pharmaceutical ingredients for analyzed tablets, flavorants inherent to food products, etc. Low part-per-million detection limits were observed but were shown dependent on sample composition.
    Conclusions: PSI-MS and FCSI-MS were successful in detecting trace-level NAMS in complex liquid- and solid-phase matrices with little to no prior preparation. This work suggests that these methodologies can provide a means for assessing problematic pharmaceutical adulterants/degradants for expedited quality control, as well as enhancing environmental stewardship efforts and forensic investigations.
    MeSH term(s) Spectrometry, Mass, Electrospray Ionization/methods ; Forensic Medicine ; Nitrosamines/analysis ; Tablets
    Chemical Substances Nitrosamines ; Tablets
    Language English
    Publishing date 2023-03-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 58731-x
    ISSN 1097-0231 ; 0951-4198
    ISSN (online) 1097-0231
    ISSN 0951-4198
    DOI 10.1002/rcm.9493
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  9. Article ; Online: Storylines of family medicine III: core principles-primary care, systems and family.

    Ventres, William B / Stone, Leslie A / Joslin, Timothy A / Saultz, John W / Aldulaimi, Sommer / Gordon, Paul R / Lane, John C / Lee, Eric R / Prunuske, Jacob / Gildenblatt, Limor / Friedman, Michael H / Fogarty, Colleen T / McDaniel, Susan H / Rohrberg, Tessa / Odom, Amy

    Family medicine and community health

    2024  Volume 12, Issue Suppl 3

    Abstract: Storylines of Family ... ...

    Abstract Storylines of Family Medicine
    MeSH term(s) Humans ; Family Practice ; Physicians, Family ; Family ; Family Health ; Patient-Centered Care
    Language English
    Publishing date 2024-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2986753-8
    ISSN 2009-8774 ; 2305-6983
    ISSN (online) 2009-8774
    ISSN 2305-6983
    DOI 10.1136/fmch-2024-002790
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  10. Article ; Online: A physician communication coaching program: Developing a supportive culture of feedback to sustain and reinvigorate faculty physicians.

    McDaniel, Susan H / DeCaporale-Ryan, Lauren / Fogarty, Colleen

    Families, systems & health : the journal of collaborative family healthcare

    2020  Volume 38, Issue 2, Page(s) 184–189

    Abstract: ... measures: introductions (I), asking about concerns (C), and check for understanding (U), or ICU ... to physicians throughout our institution. (PsycInfo Database Record (c) 2020 APA, all rights reserved). ...

    Abstract Introduction: Physician-patient communication involves complex skills that affect quality, outcome, and satisfaction for patients, families, and health care teams. Yet, institutional, regulatory, and scientific demands compete for physicians' attention. A framework is needed to support physicians continued development of communication skills: Coaching is 1 such evidence-based practice, and we assessed the feasibility of implementing such a program.
    Method: Participants were 12 physicians, representing high and low scorers on the Hospital Consumer Assessment of Health Care Providers and Systems (HCAHPS) survey. We added items to capture empathy and family experience to the Calgary-Cambridge Observation Guide for the Medical Interview. Coaches observed communication associated with patient satisfaction and quality measures: introductions (I), asking about concerns (C), and check for understanding (U), or ICU. Participants received a report describing their communication behaviors, emphasizing strengths, and identifying areas for improvement.
    Results: Scores on the ICU significantly discriminated between low and high HCAHPS scorers, physicians from surgical and cognitive specialties, men and women. We collected anonymous feedback regarding the value of this training; participants recommended expanding the program.
    Discussion: Based on physician endorsement, experienced coaches are expanding the coaching program to physicians throughout our institution. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
    MeSH term(s) Adult ; Burnout, Professional/prevention & control ; Burnout, Professional/psychology ; Communication ; Faculty, Medical/psychology ; Feedback ; Female ; Humans ; Interprofessional Relations ; Male ; Mentoring/methods ; Mentoring/trends ; Social Support ; Surveys and Questionnaires
    Language English
    Publishing date 2020-06-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1326859-4
    ISSN 1939-0602 ; 1091-7527 ; 0736-1718
    ISSN (online) 1939-0602
    ISSN 1091-7527 ; 0736-1718
    DOI 10.1037/fsh0000491
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