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  1. Article ; Online: Silencing Angiotensinogen in Hypertension.

    Touyz, Rhian M

    The New England journal of medicine

    2023  Volume 389, Issue 3, Page(s) 278–281

    MeSH term(s) Humans ; Angiotensinogen/biosynthesis ; Blood Pressure/drug effects ; Blood Pressure/physiology ; Hypertension/drug therapy ; Hypertension/metabolism
    Chemical Substances Angiotensinogen (11002-13-4)
    Language English
    Publishing date 2023-07-19
    Publishing country United States
    Document type Editorial
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMe2303534
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Hypertension

    Touyz, Rhian M. / Schiffrin, Ernesto L.

    methods and protocols

    (Methods in molecular biology ; 1527 ; Springer protocols)

    2017  

    Author's details edited by Rhian M. Touyz, Ernesto L. Schiffrin
    Series title Methods in molecular biology ; 1527
    Springer protocols
    Collection
    Keywords Renin-Angiotensin-Aldosterone System ; hypertension ; molecular mechanisms ; signal transduction ; vascular physiology ; vasoactive agents and hypertension
    Language English
    Size XV, 437 Seiten, Illustrationen, Diagramme, 25.4 cm x 17.8 cm, 0 g
    Publisher Humana Press
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT019151879
    ISBN 978-1-4939-6623-3 ; 1-4939-6623-5 ; 9781493966257 ; 1493966251
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    Zs A 7042 -1527- verfügbar in Königswinter Königswinter

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  3. Article ; Online: Hypertension

    Touyz, Rhian M

    Hypertension (Dallas, Tex. : 1979)

    2022  Volume 79, Issue 8, Page(s) 1559–1562

    MeSH term(s) Forecasting ; Humans ; Hypertension/diagnosis ; Hypertension/drug therapy
    Language English
    Publishing date 2022-07-13
    Publishing country United States
    Document type Editorial
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.122.19564
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: TRPV4 Channel-Regulated Microdomains Define a New Paradigm in Hypertension.

    Touyz, Rhian M

    Circulation

    2022  Volume 146, Issue 7, Page(s) 565–568

    MeSH term(s) Calcium/metabolism ; Humans ; Hypertension/diagnosis ; TRPV Cation Channels/genetics ; Vasodilation
    Chemical Substances TRPV Cation Channels ; TRPV4 protein, human ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2022-08-15
    Publishing country United States
    Document type Editorial
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.122.060980
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Gut Dysbiosis-Induced Hypertension Is Ameliorated by Intermittent Fasting.

    Touyz, Rhian M

    Circulation research

    2021  Volume 128, Issue 9, Page(s) 1255–1257

    MeSH term(s) Dysbiosis/therapy ; Fasting ; Gastrointestinal Microbiome ; Humans ; Hypertension/etiology ; Hypertension/therapy
    Language English
    Publishing date 2021-04-29
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.121.319147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Phenotype-Specific Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells to Model Vascular Disease: Implications of Differentiation Protocols.

    Camargo, Livia L / Touyz, Rhian M

    Hypertension (Dallas, Tex. : 1979)

    2023  Volume 80, Issue 4, Page(s) 754–756

    MeSH term(s) Humans ; Muscle, Smooth, Vascular ; Induced Pluripotent Stem Cells/physiology ; Cell Differentiation ; Phenotype ; Vascular Diseases ; Myocytes, Smooth Muscle/physiology
    Language English
    Publishing date 2023-03-15
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.123.20871
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Clinical Science: translating molecular bioscience and experimental research into medical insights.

    Touyz, Rhian M

    Clinical science (London, England : 1979)

    2020  Volume 134, Issue 4, Page(s) 435–437

    Abstract: In this Editorial, Rhian Touyz, Editor-in-Chief of Clinical Science, reflects on how the journal ...

    Abstract In this Editorial, Rhian Touyz, Editor-in-Chief of Clinical Science, reflects on how the journal has grown, highlights the journal's multidisciplinary scope and shares ambitions on exciting new aims and initiatives for the journal as we look forward.
    Language English
    Publishing date 2020-02-27
    Publishing country England
    Document type Editorial
    ZDB-ID 206835-7
    ISSN 1470-8736 ; 0301-0538 ; 0009-0360 ; 0143-5221
    ISSN (online) 1470-8736
    ISSN 0301-0538 ; 0009-0360 ; 0143-5221
    DOI 10.1042/CS20200182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A Message to the Hypertension Community Regarding the Ukraine Crisis.

    Touyz, Rhian M / Harrison, David G

    Hypertension (Dallas, Tex. : 1979)

    2022  Volume 79, Issue 6, Page(s) 1145–1146

    MeSH term(s) Humans ; Hypertension/diagnosis ; Hypertension/epidemiology ; Ukraine/epidemiology
    Language English
    Publishing date 2022-03-17
    Publishing country United States
    Document type Editorial
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.122.19357
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Clinical Science Editorial 2020 - a year gone by and the year ahead.

    Touyz, Rhian M

    Clinical science (London, England : 1979)

    2020  Volume 134, Issue 24, Page(s) 3233–3235

    Abstract: As this extraordinary year, blemished by COVID-19, comes to an end, I look back as Editor-in-Chief to the many great successes and new initiatives of Clinical Science. Despite the challenges we all faced during 2020, our journal has remained strong and ... ...

    Abstract As this extraordinary year, blemished by COVID-19, comes to an end, I look back as Editor-in-Chief to the many great successes and new initiatives of Clinical Science. Despite the challenges we all faced during 2020, our journal has remained strong and vibrant. While we have all adapted to new working conditions, with life very different to what it was pre-COVID-19, the one thing that remains intact and secure is the communication of scientific discoveries through peer-reviewed journals. I am delighted to share with you some of the many achievements of our journal over the past year and to highlight some exciting new activities planned for 2021.
    MeSH term(s) Biomedical Research/standards ; Biomedical Research/statistics & numerical data ; Biomedical Research/trends ; COVID-19/epidemiology ; COVID-19/immunology ; COVID-19/virology ; COVID-19 Vaccines/administration & dosage ; COVID-19 Vaccines/immunology ; Editorial Policies ; Forecasting ; Humans ; Pandemics/prevention & control ; Periodicals as Topic/standards ; Periodicals as Topic/statistics & numerical data ; Periodicals as Topic/trends ; SARS-CoV-2/immunology ; SARS-CoV-2/physiology
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2020-10-23
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 206835-7
    ISSN 1470-8736 ; 0301-0538 ; 0009-0360 ; 0143-5221
    ISSN (online) 1470-8736
    ISSN 0301-0538 ; 0009-0360 ; 0143-5221
    DOI 10.1042/CS20201502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Hypertension Guidelines: Effect of Blood Pressure Targets.

    Touyz, Rhian M

    The Canadian journal of cardiology

    2019  Volume 35, Issue 5, Page(s) 564–569

    Abstract: There has been an abundance of hypertension guidelines over the years. Their purpose is to convey evidence-based findings from clinical trials to clinicians so that best medical choices can be made for the diagnosis and treatment of patients with ... ...

    Abstract There has been an abundance of hypertension guidelines over the years. Their purpose is to convey evidence-based findings from clinical trials to clinicians so that best medical choices can be made for the diagnosis and treatment of patients with hypertension. Over the past 3 years new hypertension guidelines have been published in the United States, Canada, Europe, and elsewhere with new or refined recommendations made regarding diagnosis, therapy, and intensity of treatment. Previous national guidelines were generally well aligned. However, there are major differences in the current North American and European recommendations in terms of the classification of hypertension and treatment goals, with the diagnosis of hypertension starting at 140/90 mm Hg for the European guidelines and 130/80 mm Hg for the American and Canadian guidelines. An important controversial aspect in the updated guidelines relates to a lowered threshold (130/80 mm Hg) at which hypertension is diagnosed and treated, because growing evidence indicates that individuals at low cardiovascular risk might be exposed to incremental harm because of overtreatment with antihypertensive drugs. However, these concerns need to be weighed against the robust evidence from the landmark Systolic Blood Pressure Intervention Trial (SPRINT) study and numerous meta-analyses, which clearly showed that intensive blood pressure-lowering aimed at a systolic blood pressure of 120-130 mm Hg causes ̴a significant, > 25% reduction in cardiovascular morbidity and mortality. This review highlights some of the important discrepancies between the major current guidelines, with a focus on definitions and treatment goals of hypertension. The effect of lower blood pressure targets and intensive antihypertensive treatment on cardiovascular benefit and risk is also discussed.
    MeSH term(s) Antihypertensive Agents/administration & dosage ; Antihypertensive Agents/adverse effects ; Cardiovascular Diseases/prevention & control ; Cognitive Dysfunction ; Dementia ; Humans ; Hypertension/diagnosis ; Hypertension/drug therapy ; Practice Guidelines as Topic ; Randomized Controlled Trials as Topic ; Renal Insufficiency, Chronic/etiology
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2019-03-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2019.03.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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