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  1. Book: Peptides in energy balance and obesity

    Frühbeck, Gema

    (Frontiers in nutritional science ; 4)

    2009  

    Author's details ed. by Gema Frühbeck
    Series title Frontiers in nutritional science ; 4
    Collection
    Language English
    Size XII, 398 S. : Ill., graph. Darst.
    Publisher CABI
    Publishing place Wallingford u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015550807
    ISBN 978-1-84593-407-1 ; 1-84593-407-5
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  2. Article ; Online: The obesity syndemic in the European community: towards a systems thinking approach for preventive policies.

    Frühbeck, Gema / Busetto, Luca / Carbone, Federico

    European heart journal

    2024  

    Language English
    Publishing date 2024-02-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehae066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Obesity

    Williams, Gareth / Frühbeck, Gema

    science to practice

    2009  

    Author's details Gareth Williams ; Gema Frühbeck
    Keywords Obesity ; Obesity/Prevention ; Obesity/Treatment
    Subject code 616.398
    Language English
    Size XVII, 585 S. : zahlr. Ill., graph. Darst.
    Publisher Wiley-Blackwell
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015900445
    ISBN 978-0-470-01911-5 ; 0-470-01911-5
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Peptide Polyagonists for the Treatment of Nonalcoholic Fatty Liver Disease.

    Polyzos, Stergios A / Frühbeck, Gema / Kiortsis, Dimitrios N

    Current pharmaceutical design

    2024  Volume 29, Issue 41, Page(s) 3263–3265

    MeSH term(s) Humans ; Non-alcoholic Fatty Liver Disease/drug therapy ; Glucagon-Like Peptide 1 ; Insulin ; Peptides/pharmacology ; Peptides/therapeutic use ; Diabetes Mellitus, Type 2 ; Glucagon-Like Peptide-1 Receptor ; Hypoglycemic Agents
    Chemical Substances Glucagon-Like Peptide 1 (89750-14-1) ; Insulin ; Peptides ; Glucagon-Like Peptide-1 Receptor ; Hypoglycemic Agents
    Language English
    Publishing date 2024-01-10
    Publishing country United Arab Emirates
    Document type Editorial
    ZDB-ID 1304236-1
    ISSN 1873-4286 ; 1381-6128
    ISSN (online) 1873-4286
    ISSN 1381-6128
    DOI 10.2174/0113816128279822231211101522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Phenotyping the obesities: reality or utopia?

    Portincasa, Piero / Frühbeck, Gema

    Reviews in endocrine & metabolic disorders

    2023  Volume 24, Issue 5, Page(s) 767–773

    Abstract: In this thematic issue on phenotyping the obesities, prominent international experts offer an insightful and comprehensive collection of articles covering the current knowledge in the field. In order to actually capture all the polyhedral determinants of ...

    Abstract In this thematic issue on phenotyping the obesities, prominent international experts offer an insightful and comprehensive collection of articles covering the current knowledge in the field. In order to actually capture all the polyhedral determinants of the diverse types of obesity, the granularity of the phenotypic information acquired must be expanded in the context of a personalized approach. Whilst the use of precision medicine has been successfully implemented in areas like cancer and other diseases, health care providers are more reluctant to embrace detailed phenotyping to guide diagnosis, treatment and prevention in obesity. Given its multiple complex layers, phenotyping necessarily needs to go beyond the multi-omics approach and incorporate all the diverse spheres that conform the reality of people living with obesity. Potential barriers, difficulties, roadblocks and opportunities together with their interaction in a syndemic context are analyzed. Plausible lacunae are also highlighted in addition to pointing to the need of redefining new conceptual frameworks. Therefore, this extraordinary collection of state-ofthe-art reviews provides useful information to both experienced clinicians and trainees as well as academics to steer clinical practice and research in the management of people living with obesity irrespective of practice setting or career stage.
    MeSH term(s) Humans ; Utopias ; Obesity/diagnosis
    Language English
    Publishing date 2023-08-04
    Publishing country Germany
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2185718-0
    ISSN 1573-2606 ; 1389-9155
    ISSN (online) 1573-2606
    ISSN 1389-9155
    DOI 10.1007/s11154-023-09829-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Cagrilintide plus semaglutide for obesity management.

    Becerril, Sara / Frühbeck, Gema

    Lancet (London, England)

    2021  Volume 397, Issue 10286, Page(s) 1687–1689

    MeSH term(s) Glucagon-Like Peptides ; Humans ; Islet Amyloid Polypeptide ; Obesity Management
    Chemical Substances Islet Amyloid Polypeptide ; semaglutide (53AXN4NNHX) ; Glucagon-Like Peptides (62340-29-8) ; cagrilintide (AO43BIF1U8)
    Language English
    Publishing date 2021-04-22
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(21)00944-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Relevance of body composition in phenotyping the obesities.

    Salmón-Gómez, Laura / Catalán, Victoria / Frühbeck, Gema / Gómez-Ambrosi, Javier

    Reviews in endocrine & metabolic disorders

    2023  Volume 24, Issue 5, Page(s) 809–823

    Abstract: Obesity is the most extended metabolic alteration worldwide increasing the risk for the development of cardiometabolic alterations such as type 2 diabetes, hypertension, and dyslipidemia. Body mass index (BMI) remains the most frequently used tool for ... ...

    Abstract Obesity is the most extended metabolic alteration worldwide increasing the risk for the development of cardiometabolic alterations such as type 2 diabetes, hypertension, and dyslipidemia. Body mass index (BMI) remains the most frequently used tool for classifying patients with obesity, but it does not accurately reflect body adiposity. In this document we review classical and new classification systems for phenotyping the obesities. Greater accuracy of and accessibility to body composition techniques at the same time as increased knowledge and use of cardiometabolic risk factors is leading to a more refined phenotyping of patients with obesity. It is time to incorporate these advances into routine clinical practice to better diagnose overweight and obesity, and to optimize the treatment of patients living with obesity.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/diagnosis ; Waist Circumference ; Obesity ; Body Mass Index ; Adiposity ; Body Composition ; Risk Factors
    Language English
    Publishing date 2023-03-17
    Publishing country Germany
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2185718-0
    ISSN 1573-2606 ; 1389-9155
    ISSN (online) 1573-2606
    ISSN 1389-9155
    DOI 10.1007/s11154-023-09796-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Towards an adiposity-related disease framework for the diagnosis and management of obesities.

    Perdomo, Carolina M / Avilés-Olmos, Icíar / Dicker, Dror / Frühbeck, Gema

    Reviews in endocrine & metabolic disorders

    2023  Volume 24, Issue 5, Page(s) 795–807

    Abstract: Obesity is a complex disease that relapses frequently and associates with multiple complications that comprise a worldwide health priority because of its rising prevalence and association with numerous complications, including metabolic disorders, ... ...

    Abstract Obesity is a complex disease that relapses frequently and associates with multiple complications that comprise a worldwide health priority because of its rising prevalence and association with numerous complications, including metabolic disorders, mechanic pathologies, and cancer, among others. Noteworthy, excess adiposity is accompanied by chronic inflammation, oxidative stress, insulin resistance, and subsequent organ dysfunction. This dysfunctional adipose tissue is initially stored in the visceral depot, overflowing subsequently to produce lipotoxicity in ectopic depots like liver, heart, muscle, and pancreas, among others. People living with obesity need a diagnostic approach that considers an exhaustive pathophysiology and complications assessment. Thus, it is essential to warrant a holistic diagnosis and management that guarantees an adequate health status, and quality of life. The present review summarizes the different complications associated with obesity, at the same time, we aim to fostering a novel framework that enhances a patient-centered approach to obesity management in the precision medicine era.
    MeSH term(s) Humans ; Adiposity ; Quality of Life ; Obesity/diagnosis ; Obesity/therapy ; Obesity/complications ; Adipose Tissue/metabolism ; Inflammation/metabolism ; Insulin Resistance/physiology
    Language English
    Publishing date 2023-05-10
    Publishing country Germany
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2185718-0
    ISSN 1573-2606 ; 1389-9155
    ISSN (online) 1573-2606
    ISSN 1389-9155
    DOI 10.1007/s11154-023-09797-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Benefits of Bariatric Surgery Prior to SARS-CoV-2 Infection in Modulating the Response to COVID-19.

    Landecho, Manuel F / Frühbeck, Gema

    Obesity (Silver Spring, Md.)

    2020  Volume 29, Issue 1, Page(s) 19

    MeSH term(s) Bariatric Surgery ; COVID-19 ; Humans ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-12-03
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2230457-5
    ISSN 1930-739X ; 1071-7323 ; 1930-7381
    ISSN (online) 1930-739X
    ISSN 1071-7323 ; 1930-7381
    DOI 10.1002/oby.23059
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Metrics: Reflections on the 2020s impact factors.

    Gómez-Ambrosi, Javier / Catalán, Victoria / Frühbeck, Gema

    European journal of clinical investigation

    2021  Volume 52, Issue 5, Page(s) e13723

    MeSH term(s) Benchmarking ; Humans
    Language English
    Publishing date 2021-12-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 186196-7
    ISSN 1365-2362 ; 0014-2972 ; 0960-135X
    ISSN (online) 1365-2362
    ISSN 0014-2972 ; 0960-135X
    DOI 10.1111/eci.13723
    Database MEDical Literature Analysis and Retrieval System OnLINE

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